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WO2007049264A3 - Essais biologiques contenant des particules - Google Patents

Essais biologiques contenant des particules Download PDF

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Publication number
WO2007049264A3
WO2007049264A3 PCT/IE2006/000123 IE2006000123W WO2007049264A3 WO 2007049264 A3 WO2007049264 A3 WO 2007049264A3 IE 2006000123 W IE2006000123 W IE 2006000123W WO 2007049264 A3 WO2007049264 A3 WO 2007049264A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
buffered
assays
test sample
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IE2006/000123
Other languages
English (en)
Other versions
WO2007049264A2 (fr
Inventor
Yuri Volkov
Yury Rakovich
Iouri Kuzmich Gounko
John Dongegan
Dermot Kelleher
Siobhan Mitchell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Original Assignee
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin filed Critical College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Priority to US12/084,239 priority Critical patent/US20090197291A1/en
Publication of WO2007049264A2 publication Critical patent/WO2007049264A2/fr
Publication of WO2007049264A3 publication Critical patent/WO2007049264A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

L'invention concerne un procédé pour déterminer de manière quantitative et qualitative la présence d'une macromolécule comprenant la création de nanoparticules dans une solution tamponnée, l'ajout d'un échantillon test à la solution de nanoparticules tamponnées, et la mesure de la différence entre les nanoparticules tamponnées en présence ou en l'absence de l'échantillon test. Les nanoparticules présentent une taille inférieure à 100 nm.
PCT/IE2006/000123 2005-10-27 2006-10-27 Essais biologiques contenant des particules Ceased WO2007049264A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/084,239 US20090197291A1 (en) 2005-10-27 2006-10-27 Assays Using Nanoparticles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73036505P 2005-10-27 2005-10-27
US60/730,365 2005-10-27

Publications (2)

Publication Number Publication Date
WO2007049264A2 WO2007049264A2 (fr) 2007-05-03
WO2007049264A3 true WO2007049264A3 (fr) 2007-07-19

Family

ID=37714424

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IE2006/000123 Ceased WO2007049264A2 (fr) 2005-10-27 2006-10-27 Essais biologiques contenant des particules

Country Status (1)

Country Link
WO (1) WO2007049264A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6114038A (en) * 1998-11-10 2000-09-05 Biocrystal Ltd. Functionalized nanocrystals and their use in detection systems
US6306610B1 (en) * 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
US6468808B1 (en) * 1998-09-24 2002-10-22 Advanced Research And Technology Institute, Inc. Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306610B1 (en) * 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
US6468808B1 (en) * 1998-09-24 2002-10-22 Advanced Research And Technology Institute, Inc. Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use
US6114038A (en) * 1998-11-10 2000-09-05 Biocrystal Ltd. Functionalized nanocrystals and their use in detection systems

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LI ET AL: "Application of L-cysteine-capped ZnS nanoparticles in the determination of nucleic acid using teh resonance light scattering method", MICROCHIMICA ACTA, vol. 146, 8 March 2004 (2004-03-08), pages 13 - 19, XP002419963 *
ZHU CHANG QING ET AL: "Application of L-cysteine-capped nano-ZnS as a fluorescence probe for the determination of proteins.", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 378, no. 3, February 2004 (2004-02-01), pages 811 - 815, XP002419964, ISSN: 1618-2642 *

Also Published As

Publication number Publication date
WO2007049264A2 (fr) 2007-05-03

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