[go: up one dir, main page]

WO2007049089A8 - Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues - Google Patents

Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues

Info

Publication number
WO2007049089A8
WO2007049089A8 PCT/IB2005/003202 IB2005003202W WO2007049089A8 WO 2007049089 A8 WO2007049089 A8 WO 2007049089A8 IB 2005003202 W IB2005003202 W IB 2005003202W WO 2007049089 A8 WO2007049089 A8 WO 2007049089A8
Authority
WO
WIPO (PCT)
Prior art keywords
myocardium
regeneration
blood vessels
damaged tissues
stimulating growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2005/003202
Other languages
French (fr)
Other versions
WO2007049089A1 (en
Inventor
Ming Li
Lei Cheng
Xin-Sheng Yao
Hong-Wei Liu
John Elsby Sanderson
Xue-Mei Gu
Leonard Wing-Hong Cheung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lead Billion Ltd
Original Assignee
Lead Billion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Billion Ltd filed Critical Lead Billion Ltd
Priority to PCT/IB2005/003202 priority Critical patent/WO2007049089A1/en
Priority to CN2006800018615A priority patent/CN101137387B/en
Priority to AU2006308337A priority patent/AU2006308337B2/en
Priority to CA2593161A priority patent/CA2593161C/en
Priority to CN2006800018634A priority patent/CN101141965B/en
Priority to ES06805090T priority patent/ES2427354T3/en
Priority to EP06805090.5A priority patent/EP1848440B1/en
Priority to HK08105212.3A priority patent/HK1110784B/en
Priority to DK06805090.5T priority patent/DK1848440T3/en
Priority to JP2008529456A priority patent/JP4950996B2/en
Priority to PCT/CN2006/002886 priority patent/WO2007048353A1/en
Priority to ES06805091.3T priority patent/ES2540912T3/en
Priority to PCT/CN2006/002885 priority patent/WO2007048352A1/en
Priority to AU2006308338A priority patent/AU2006308338B2/en
Priority to EP06805091.3A priority patent/EP1848445B1/en
Priority to US11/722,911 priority patent/US20080124388A1/en
Priority to CA2593171A priority patent/CA2593171C/en
Priority to JP2008529455A priority patent/JP5117386B2/en
Priority to HK08108022.7A priority patent/HK1112848B/en
Priority to US11/722,915 priority patent/US9155744B2/en
Priority to DK06805091.3T priority patent/DK1848445T3/en
Publication of WO2007049089A1 publication Critical patent/WO2007049089A1/en
Publication of WO2007049089A8 publication Critical patent/WO2007049089A8/en
Anticipated expiration legal-status Critical
Priority to US13/517,600 priority patent/US20120252744A1/en
Priority to US14/843,898 priority patent/US20160058797A1/en
Priority to US15/380,659 priority patent/US20170095495A1/en
Priority to US15/462,626 priority patent/US20170189432A1/en
Priority to US16/398,026 priority patent/US20190358251A1/en
Priority to US16/409,511 priority patent/US20200101096A1/en
Priority to US17/070,881 priority patent/US20210268010A1/en
Priority to US17/456,763 priority patent/US20220152070A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Use of the effective constituents from an extract of Geum Japonicum for the manufacture of a medicament for stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues. The effective constituents from an extract of Geum Japonicum are Gemin A and Niga-ichigoside F1.
PCT/IB2005/003202 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues Ceased WO2007049089A1 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
PCT/IB2005/003202 WO2007049089A1 (en) 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues
CA2593171A CA2593171C (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
US11/722,911 US20080124388A1 (en) 2005-10-27 2006-10-27 Pharmaceutical Composition And Method For Neoangiogenesis/Revascularization Useful In Treating Ischemic Heart Diseases
CA2593161A CA2593161C (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
CN2006800018634A CN101141965B (en) 2005-10-27 2006-10-27 Pharmaceutical composition for regenerating muscle fibers in the treatment of muscle damage
ES06805090T ES2427354T3 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method to regenerate myofibers in the treatment of muscle injuries
EP06805090.5A EP1848440B1 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
HK08105212.3A HK1110784B (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
DK06805090.5T DK1848440T3 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibres in the treatment of muscle injuries
JP2008529455A JP5117386B2 (en) 2005-10-27 2006-10-27 Pharmaceutical compositions and methods for regeneration of muscle fibers in the treatment of muscle injury
PCT/CN2006/002886 WO2007048353A1 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
ES06805091.3T ES2540912T3 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and neoangiogenesis / revascularization method useful in the treatment of ischemic heart disease
PCT/CN2006/002885 WO2007048352A1 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
AU2006308338A AU2006308338B2 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
EP06805091.3A EP1848445B1 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
CN2006800018615A CN101137387B (en) 2005-10-27 2006-10-27 Pharmaceutical compositions and methods for neovascularization/revascularization useful for treating ischemic heart disease
HK08108022.7A HK1112848B (en) 2005-10-27 2006-10-27 Pharmaceutical composition for regenerating myofibers in the treatment of muscle injuries
JP2008529456A JP4950996B2 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for angiogenesis / revascularization useful for the treatment of ischemic heart disease
AU2006308337A AU2006308337B2 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
US11/722,915 US9155744B2 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
DK06805091.3T DK1848445T3 (en) 2005-10-27 2006-10-27 Pharmaceutical composition and method of neoangiogenesis / revascularization useful in the treatment of ischemic heart disease
US13/517,600 US20120252744A1 (en) 2005-10-27 2012-06-14 Pharmaceutical Composition and Method for Neoangiogenesis/Revascularization Useful in Treating Ischemic Heart Disease
US14/843,898 US20160058797A1 (en) 2005-10-27 2015-09-02 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
US15/380,659 US20170095495A1 (en) 2005-10-27 2016-12-15 Pharmaceutical Composition and Method for Neoangiogenesis/Revascularization Useful in Treating Ischemic Heart Disease
US15/462,626 US20170189432A1 (en) 2005-10-27 2017-03-17 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
US16/398,026 US20190358251A1 (en) 2005-10-27 2019-04-29 Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
US16/409,511 US20200101096A1 (en) 2005-10-27 2019-05-10 Pharmaceutical Composition and Method for Neoangiogenesis/Revascularization Useful in Treating Ischemic Heart Disease
US17/070,881 US20210268010A1 (en) 2005-10-27 2020-10-14 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart disease
US17/456,763 US20220152070A1 (en) 2005-10-27 2021-11-29 Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2005/003202 WO2007049089A1 (en) 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues

Publications (2)

Publication Number Publication Date
WO2007049089A1 WO2007049089A1 (en) 2007-05-03
WO2007049089A8 true WO2007049089A8 (en) 2007-09-13

Family

ID=36218724

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/003202 Ceased WO2007049089A1 (en) 2005-10-27 2005-10-27 Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues

Country Status (2)

Country Link
CN (1) CN101141965B (en)
WO (1) WO2007049089A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1848445B1 (en) 2005-10-27 2015-04-01 Lead Billion Limited Pharmaceutical composition and method for neoangiogenesis/revascularization useful in treating ischemic heart diseases
CN102573865B (en) * 2009-06-12 2016-08-24 基因雷克斯制药有限公司 Composition for prevention and treatment of erythrocyte aggregation
EP2655390B1 (en) * 2010-12-23 2019-03-27 Huya Bioscience International LLC Purified cardiogenin isomer and related methods
CN102499932B (en) * 2011-11-04 2013-03-06 中国人民武装警察部队后勤学院 Application of multinoside to preparing anti-hypoxia medicament
CN103193855B (en) * 2013-04-02 2015-07-29 沈阳化工大学 A kind of preparation method of cherokee rose fruit saponin monomer
EP3612193A4 (en) * 2017-04-20 2020-12-30 North Carolina State University THROMBOCYTE VESICLE-MANIPULATED CELLS AND EXTRACELLULAR VESICLE FOR TARGETED TISSUE REPAIR
CN114028459A (en) * 2021-11-11 2022-02-11 杭州科贝生物制药有限公司 Medicine for preventing and treating mammal ischemic heart disease, preparation method and application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916919A (en) * 1997-06-27 1999-06-29 Dalhousie University Retrovirus protease inhibitors
DE60143132D1 (en) * 2001-11-21 2010-11-04 Univ Hong Kong Chinese COMPOSITIONS OF ORGANIC EXTRACTS OF GEUM JAPONICUM THUNB VAR. AND YOUR USE
AU2002350380B2 (en) * 2002-12-10 2006-11-16 Lead Billion Limited An organic extract of Geum Japonicum thumb variant and use thereof

Also Published As

Publication number Publication date
CN101141965B (en) 2011-01-26
CN101141965A (en) 2008-03-12
WO2007049089A1 (en) 2007-05-03

Similar Documents

Publication Publication Date Title
WO2005067660A3 (en) Prosthesis systems and methods sized and configured for the receipt and retention of fasteners
CY2018026I1 (en) USE OF STRATUM STEM CELLS DERIVED FROM FATTY TISSUE IN THE TREATMENT OF FISTULA
WO2007134126A3 (en) After-loader devices and kits and methods for their use
WO2007035843A3 (en) Methods and compositions for organ and tissue functionality
WO2006044467A3 (en) Method and device for percutaneous left ventricular reconstruction
WO2005094553A3 (en) Compositions for promoting bone growth and methods thereof
WO2007016097A3 (en) Implantable prosthetic vascular valve
WO2008019116A3 (en) Implantable medical device with particulate coating
EP2197270B8 (en) Placental tissue grafts and improved methods of preparing and using the same
IL190565A (en) Implantable device for endovascularly clipping and repairing lumen and tissue defects
WO2006118801A3 (en) Multi-purpose medical implant devices
WO2005065418A3 (en) Compositions and methods of use of targeting peptides for diagnosis and therapy
WO2009022907A3 (en) A method for identifying, expanding, and removing adult stem cells and cancer stem cells
WO2008005888A3 (en) Atherectomy devices and methods
EP1933715A4 (en) System and method for characterizing vascular tissue
WO2006026730A3 (en) Cultured three dimensional tissues and uses thereof
WO2007046989A3 (en) Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy
WO2009117435A3 (en) Devices and methods for percutaneous access, hemostasis, and closure
WO2008103781A3 (en) Devices for treating the spine
GB0504988D0 (en) Device and method for the treatment of diseased tissue such as tumors
WO2006096793A3 (en) Medical implants
EP2061548A4 (en) Apparatus and methods for delivering stem cells and other agents into cardiac tissue
WO2007089508A3 (en) Medical tools for facilitating deep lamellar endothelial keratoplasty and related methods
WO2007008983A3 (en) Systems and methods for providing prostheses
WO2007049089A8 (en) Method of stimulating growth of functional blood vessels and/or regeneration of myocardium in damaged tissues

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 05801768

Country of ref document: EP

Kind code of ref document: A1