[go: up one dir, main page]

WO2007044751A3 - Polynucleotides encoding phenylpropanoid pathway enzymes in coffee - Google Patents

Polynucleotides encoding phenylpropanoid pathway enzymes in coffee Download PDF

Info

Publication number
WO2007044751A3
WO2007044751A3 PCT/US2006/039618 US2006039618W WO2007044751A3 WO 2007044751 A3 WO2007044751 A3 WO 2007044751A3 US 2006039618 W US2006039618 W US 2006039618W WO 2007044751 A3 WO2007044751 A3 WO 2007044751A3
Authority
WO
WIPO (PCT)
Prior art keywords
coffee
polynucleotides encoding
pathway enzymes
phenylpropanoid pathway
polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/039618
Other languages
French (fr)
Other versions
WO2007044751A2 (en
Inventor
Maud Lepelley
Gerald Cheminade
James Gerard Mccarthy
Vincent Petiard
Chenwei Lin
Steven D Tanksley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nestec SA
Cornell Research Foundation Inc
Original Assignee
Nestec SA
Cornell Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec SA, Cornell Research Foundation Inc filed Critical Nestec SA
Priority to AP2008004413A priority Critical patent/AP2008004413A0/en
Priority to AU2006302107A priority patent/AU2006302107A1/en
Priority to BRPI0616979-1A priority patent/BRPI0616979A2/en
Priority to US12/083,041 priority patent/US8362328B2/en
Priority to EP06816655A priority patent/EP1940868A2/en
Priority to CA002625350A priority patent/CA2625350A1/en
Publication of WO2007044751A2 publication Critical patent/WO2007044751A2/en
Publication of WO2007044751A3 publication Critical patent/WO2007044751A3/en
Priority to EC2008008355A priority patent/ECSP088355A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Tea And Coffee (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Polynucleotides and polypeptides involved in the biosynthetic pathway of chlorogenic acids in the coffee plant are disclosed. Also disclosed are methods for using these polynucleotides and polypeptides for the manipulation of flavor, aroma, and other features of coffee beans, as well as for the protection of coffee plants against diseases or oxidative stress.
PCT/US2006/039618 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee Ceased WO2007044751A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AP2008004413A AP2008004413A0 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee
AU2006302107A AU2006302107A1 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee
BRPI0616979-1A BRPI0616979A2 (en) 2005-10-07 2006-10-10 isolated coffee nucleic acid molecule (coffea spp), mrna and cdna molecules, oligonucleotide, vector, host cell, fertile plant and method of modulating flavor or aroma of coffee beans
US12/083,041 US8362328B2 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee
EP06816655A EP1940868A2 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee
CA002625350A CA2625350A1 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee
EC2008008355A ECSP088355A (en) 2005-10-07 2008-04-07 POLYUCLEOTID CODING FOR ENZYMES OF THE PHENYLPROPANOID ROAD IN COFFEE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72467305P 2005-10-07 2005-10-07
US60/724,673 2005-10-07

Publications (2)

Publication Number Publication Date
WO2007044751A2 WO2007044751A2 (en) 2007-04-19
WO2007044751A3 true WO2007044751A3 (en) 2007-11-15

Family

ID=37943484

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/039618 Ceased WO2007044751A2 (en) 2005-10-07 2006-10-10 Polynucleotides encoding phenylpropanoid pathway enzymes in coffee

Country Status (9)

Country Link
US (1) US8362328B2 (en)
EP (1) EP1940868A2 (en)
CN (1) CN101326194A (en)
AP (1) AP2008004413A0 (en)
AU (1) AU2006302107A1 (en)
BR (1) BRPI0616979A2 (en)
CA (1) CA2625350A1 (en)
EC (1) ECSP088355A (en)
WO (1) WO2007044751A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105087592A (en) * 2015-09-23 2015-11-25 山东大学 Honeysuckle HQT gene cold inducible promoter

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102061301B (en) * 2010-08-04 2012-12-05 陕西师范大学 Hydroxyl cinnamon acyl transfer enzyme gene sequence of salvia miltiorrhiza bunge as well as coded amino acid sequence and application thereof
CN102465135A (en) * 2010-11-05 2012-05-23 中国中医科学院中药研究所 Scutellaria baicalensis Georgi caffeoyl-coenzyme A-3-O-methyltransferase (SbCCOMT2) gene and coding product and application thereof
WO2012126789A1 (en) * 2011-03-18 2012-09-27 Nestec S.A. Production of chlorogenic and dactylifric acid species
JP6316810B2 (en) * 2012-07-26 2018-04-25 カサルカ ソシエダ アノニマCasaLuker S.A. Method for increasing the production of phenolic compounds from cocoa (Theobromacacao)
CN106834246B (en) * 2016-12-30 2020-10-23 江苏省中国科学院植物研究所 Cytochrome P450 reductase 2 of Amaryllidaceae plant and its encoding gene and application
CN108795899B (en) * 2018-06-25 2021-06-04 黄冈师范学院 Application of NtCCoAOMT gene in improving chlorogenic acid production of tobacco
CN110904067B (en) * 2019-12-20 2022-08-26 中国烟草总公司郑州烟草研究院 Tobacco chlorogenic acid synthetic gene NtHQT and application thereof
CN115704004A (en) * 2021-08-05 2023-02-17 杭州唯铂莱生物科技有限公司 Method for synthesizing phenylpropanol derivative by using immobilized enzyme
CN114317304B (en) * 2021-12-21 2024-03-15 浙江工业大学 Construction method and application of chlorogenic acid-producing engineering strain of Saccharomyces cerevisiae
CN116240225B (en) * 2023-01-12 2025-05-02 中国烟草总公司郑州烟草研究院 Series tobacco NtHQT gene and application thereof
CN119060967A (en) * 2024-09-25 2024-12-03 河北省科学院生物研究所 An enzyme product and method for synthesizing chlorogenic acid

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004001028A1 (en) * 2002-06-21 2003-12-31 Plant Bioscience Limited Plant-derived transferase genes
WO2004035745A2 (en) * 2002-10-16 2004-04-29 U.S. Smokeless Tobacco Company Cloning of cytochrome p450 genes from nicotiana

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ552941A (en) * 2004-07-24 2011-02-25 Samuel Roberts Noble Found Inc Modification of the lignin biosynthesis gene hydroxycinnamoyl transferase (HCT)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004001028A1 (en) * 2002-06-21 2003-12-31 Plant Bioscience Limited Plant-derived transferase genes
WO2004035745A2 (en) * 2002-10-16 2004-04-29 U.S. Smokeless Tobacco Company Cloning of cytochrome p450 genes from nicotiana

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BUSAM GUNTHER ET AL: "Isolation of tobacco cDNA encoding caffeoyl-CoA 3-O-methyltransferase (Accession Nos. Z56282 and Z82982)", PLANT PHYSIOLOGY (ROCKVILLE), vol. 113, no. 3, 1997, pages 1003, XP009087942, ISSN: 0032-0889 *
CAMPA C ET AL: "Genetic mapping of a caffeoyl-coenzyme A 3-O-methyltransferase gene in coffee trees. Impact on chlorogenic acid content.", THEORETICAL AND APPLIED GENETICS, vol. 107, no. 4, August 2003 (2003-08-01), pages 751 - 756, XP009083044, ISSN: 0040-5752 *
DATABASE EMBL [online] 4 December 1995 (1995-12-04), BUSAM ET AL.: "N.tabacum mRNA for caffeoyl-CoA O-methyltransferase", XP002445875, retrieved from EBI accession no. EMBL:Z56282 Database accession no. Z56282 *
DATABASE UniProt [online] 1 July 1997 (1997-07-01), BUSAM ET AL.: "Caffeoyl-CoA O-methyltransferase 5 (EC 2.1.1.104) (Trans-caffeoyl-CoA 3-O-methyltransferase 5 (CCoAMT-5) (CCoAOMT-5). G", XP002445965, retrieved from EBI Database accession no. O04899 *
DATABASE UniProt [online] 1 November 1996 (1996-11-01), BUSAM ET AL.: "Caffeoyl-CoA O-methyltransferase 6 (EC 2.1.1.104) (Trans-caffeoyl-CoA 3-O-methyltransferase 6) (CCoAMT-6) (CCoAOMT-6).", XP002445964, retrieved from EBI Database accession no. Q42945 *
HOFFMANN LAURENT ET AL: "Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, no. 1, 3 January 2003 (2003-01-03), pages 95 - 103, XP009083239, ISSN: 0021-9258 *
HOFFMANN LAURENT ET AL: "Silencing of hydroxycinnamoy-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis", PLANT CELL, vol. 16, no. 6, June 2004 (2004-06-01), pages 1446 - 1465, XP009083263, ISSN: 1040-4651 *
LEPELLEY, MAUD ET AL: "Chlorogenic acid synthesis in coffee : An analysis of CGA content and real-time RT-PCR expression of HCT, HQT , C3H1, and CCoAOMT1 genes during grain development in C. canephora", PLANT SCIENCE (AMSTERDAM, NETHERLANDS) , 172(5), 978-996 CODEN: PLSCE4; ISSN: 0168-9452, 2007, XP009083025 *
NIGGEWEG RICARDA ET AL: "Engineering plants with increased levels of the antioxidant chlorogenic acid", NATURE BIOTECHNOLOGY, vol. 22, no. 6, June 2004 (2004-06-01), pages 746 - 754, XP009087941, ISSN: 1087-0156 *
SCHOCH G ET AL: "CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 276, no. 39, 28 September 2001 (2001-09-28), pages 36566 - 36574, XP002223727, ISSN: 0021-9258 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105087592A (en) * 2015-09-23 2015-11-25 山东大学 Honeysuckle HQT gene cold inducible promoter

Also Published As

Publication number Publication date
ECSP088355A (en) 2008-06-30
US20090158456A1 (en) 2009-06-18
CA2625350A1 (en) 2007-04-19
CN101326194A (en) 2008-12-17
BRPI0616979A2 (en) 2011-07-05
WO2007044751A2 (en) 2007-04-19
AP2008004413A0 (en) 2008-04-30
EP1940868A2 (en) 2008-07-09
AU2006302107A1 (en) 2007-04-19
US8362328B2 (en) 2013-01-29

Similar Documents

Publication Publication Date Title
ECSP088355A (en) POLYUCLEOTID CODING FOR ENZYMES OF THE PHENYLPROPANOID ROAD IN COFFEE
WO2007109802A3 (en) Extracts and methods comprising green tea species
ZA200804460B (en) Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
WO2005094235A3 (en) Toasted soybean flakes and method of making same
SI2436269T1 (en) Coffee composition consisting of soluble, freeze-dried and finely ground natural roasted coffee which has the taste and aroma of freshly roasted natural coffee, and method for producing said composition
MY156443A (en) Tea extract, tea beverage, and method of making the same
WO2007109804A3 (en) Extracts and methods comprising cinnamon species
TW200612841A (en) Method of preparing tea extract and tea flavor
WO2007098205A3 (en) Cocoa products and methods of treating cardiovascular conditions with sugar-free cocoa
UA95906C2 (en) Coffee product
WO2003101216A3 (en) Coffee aroma having an improved stability
TW200518681A (en) Preparation process of tea extract
WO2007022318A3 (en) Nucleic acids and proteins associated with sucrose accumulation in coffee
WO2006119510A3 (en) Isoforms of receptor for advanced glycation end products (rage) and methods of identifying and using same
EP1841404A4 (en) Skin-condition improving composition comprising vaccinium uliginosum extract and method for preparation thereof
WO2002030941A3 (en) Topoisomerase inhibitors
WO2007038566A3 (en) Invertase and inhibitors from coffee
WO2005028610A3 (en) The use of labiatae herb preparations for foam enchancement of beverages
WO2007033066A3 (en) Sweetener and aroma compositions
PL1631151T3 (en) Pulverulent composition containing roast coffee
WO2005070183A3 (en) Ice cream and ice cream formulations containing maltitol
WO2007028115A3 (en) Polynucleotides encoding carotenoid and apocarotenoid biosynthetic pathway
WO2006078699A3 (en) Oral care compositions derived from the labiatae family
WO2009050905A1 (en) Taste-improving composition, food and drink containing the same and methods of producing them
WO2005115131A3 (en) Compositions containing a nopal cactus isolate and method for making same

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680045889.9

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006816655

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2006302107

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2625350

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: MX/a/2008/004640

Country of ref document: MX

Ref document number: 2871/DELNP/2008

Country of ref document: IN

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006302107

Country of ref document: AU

Date of ref document: 20061010

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 08042078

Country of ref document: CO

WWE Wipo information: entry into national phase

Ref document number: 12083041

Country of ref document: US

ENP Entry into the national phase

Ref document number: PI0616979

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20080407