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WO2006131679A3 - Dispositif planaire avec adressage de puits automatise par electromouillage dynamique - Google Patents

Dispositif planaire avec adressage de puits automatise par electromouillage dynamique Download PDF

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Publication number
WO2006131679A3
WO2006131679A3 PCT/FR2006/050534 FR2006050534W WO2006131679A3 WO 2006131679 A3 WO2006131679 A3 WO 2006131679A3 FR 2006050534 W FR2006050534 W FR 2006050534W WO 2006131679 A3 WO2006131679 A3 WO 2006131679A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrowetting
dynamic
planar device
automated
well addressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2006/050534
Other languages
English (en)
Other versions
WO2006131679A2 (fr
Inventor
Fabien Sauter-Starace
Yves Fouillet
Hahan Nathalie Picollet-D
Francois Chatelain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to US11/916,751 priority Critical patent/US20080185296A1/en
Priority to EP06764854A priority patent/EP1889053A2/fr
Publication of WO2006131679A2 publication Critical patent/WO2006131679A2/fr
Publication of WO2006131679A3 publication Critical patent/WO2006131679A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1022—Measurement of deformation of individual particles by non-optical means

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

L'invention concerne un procédé d'analyse d'un liquide d'une goutte (2) comportant : la mise en contact d'une goutte de ce liquide avec une surface hydrophobe (8), le déplacement de la goutte sur cette surface par électromouillage, afin de l'amener en un site (24, 26, 28) de mesure d'activité électrique, dans lequel est disposée une solution conductrice (42), la mesure de ladite activité électrique.
PCT/FR2006/050534 2005-06-09 2006-06-07 Dispositif planaire avec adressage de puits automatise par electromouillage dynamique Ceased WO2006131679A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/916,751 US20080185296A1 (en) 2005-06-09 2006-06-07 Planar Device With Well Addressing Automated By Dynamic Electrowetting
EP06764854A EP1889053A2 (fr) 2005-06-09 2006-06-07 Dispositif planaire avec adressage de puits automatise par electromouillage dynamique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0551557A FR2887030B1 (fr) 2005-06-09 2005-06-09 Dispositif planaire avec adressage de puits automatise par electromouillage dynamique
FR0551557 2005-06-09

Publications (2)

Publication Number Publication Date
WO2006131679A2 WO2006131679A2 (fr) 2006-12-14
WO2006131679A3 true WO2006131679A3 (fr) 2007-02-01

Family

ID=35709166

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2006/050534 Ceased WO2006131679A2 (fr) 2005-06-09 2006-06-07 Dispositif planaire avec adressage de puits automatise par electromouillage dynamique

Country Status (4)

Country Link
US (1) US20080185296A1 (fr)
EP (1) EP1889053A2 (fr)
FR (1) FR2887030B1 (fr)
WO (1) WO2006131679A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2887305B1 (fr) 2005-06-17 2011-05-27 Commissariat Energie Atomique Dispositif de pompage par electromouillage et application aux mesures d'activite electrique
US9631244B2 (en) 2007-10-17 2017-04-25 Advanced Liquid Logic, Inc. Reagent storage on a droplet actuator
US8460528B2 (en) * 2007-10-17 2013-06-11 Advanced Liquid Logic Inc. Reagent storage and reconstitution for a droplet actuator
FR2930457B1 (fr) * 2008-04-24 2010-06-25 Commissariat Energie Atomique Procede de fabrication de microcanaux reconfigurables
FR2933713B1 (fr) * 2008-07-11 2011-03-25 Commissariat Energie Atomique Procede et dispositif de manipulation et d'observation de gouttes de liquide
US8877512B2 (en) * 2009-01-23 2014-11-04 Advanced Liquid Logic, Inc. Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator
CN103170383B (zh) * 2013-03-10 2015-05-13 复旦大学 基于纳米材料电极修饰的电化学集成数字微流控芯片
CN103406161A (zh) * 2013-07-05 2013-11-27 复旦大学 一种能产生精确液滴的数字微流芯片
CN108885379B (zh) * 2016-03-24 2021-10-12 夏普株式会社 电润湿装置以及电润湿装置的制造方法
US11040345B2 (en) 2016-03-30 2021-06-22 Sharp Life Science (Eu) Limited Microfluidic device
CN113090785B (zh) * 2021-03-29 2022-12-09 广州大学 一种基于介电润湿控制的四通道微阀

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002003058A2 (fr) * 2000-07-05 2002-01-10 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Dispositif et procede pour mettre en contact electrique des cellules biologiques en suspension dans un liquide
FR2841063A1 (fr) * 2002-06-18 2003-12-19 Commissariat Energie Atomique Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
US20040055536A1 (en) * 2002-09-24 2004-03-25 Pramod Kolar Method and apparatus for non-contact electrostatic actuation of droplets

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
DE60228685D1 (de) * 2002-05-16 2008-10-16 Micronit Microfluidics Bv Verfahren zur Herstellung eines mikrofluidischen Bauteiles
FR2844052B1 (fr) * 2002-08-28 2005-07-01 Commissariat Energie Atomique Dispositif de mesure de l'activite electrique d'elements biologiques et ses applications
FR2866493B1 (fr) * 2004-02-16 2010-08-20 Commissariat Energie Atomique Dispositif de controle du deplacement d'une goutte entre deux ou plusieurs substrats solides
DE602005024418D1 (de) * 2004-08-26 2010-12-09 Life Technologies Corp Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002003058A2 (fr) * 2000-07-05 2002-01-10 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Dispositif et procede pour mettre en contact electrique des cellules biologiques en suspension dans un liquide
FR2841063A1 (fr) * 2002-06-18 2003-12-19 Commissariat Energie Atomique Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
US20040055536A1 (en) * 2002-09-24 2004-03-25 Pramod Kolar Method and apparatus for non-contact electrostatic actuation of droplets

Also Published As

Publication number Publication date
US20080185296A1 (en) 2008-08-07
FR2887030B1 (fr) 2008-06-13
EP1889053A2 (fr) 2008-02-20
WO2006131679A2 (fr) 2006-12-14
FR2887030A1 (fr) 2006-12-15

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