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WO2006129056A3 - Process and novel salt - Google Patents

Process and novel salt Download PDF

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Publication number
WO2006129056A3
WO2006129056A3 PCT/GB2006/001830 GB2006001830W WO2006129056A3 WO 2006129056 A3 WO2006129056 A3 WO 2006129056A3 GB 2006001830 W GB2006001830 W GB 2006001830W WO 2006129056 A3 WO2006129056 A3 WO 2006129056A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel salt
novel
salts
compositions
novels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2006/001830
Other languages
French (fr)
Other versions
WO2006129056A2 (en
Inventor
Kreso Mihaljevic
Blazenko Bajic
Drazen Cavuzic
Ruzica Oreskovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Hrvatska doo
Original Assignee
Pliva Hrvatska doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0511000A external-priority patent/GB0511000D0/en
Priority claimed from GB0515775A external-priority patent/GB0515775D0/en
Application filed by Pliva Hrvatska doo filed Critical Pliva Hrvatska doo
Priority to EP06727135A priority Critical patent/EP1888606A2/en
Publication of WO2006129056A2 publication Critical patent/WO2006129056A2/en
Publication of WO2006129056A3 publication Critical patent/WO2006129056A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to a process of preparing risedronic acid, or a pharmaceutically acceptable salt thereof, novel risedronate ammonium salts and pharmaceutical compositions thereof, and the use of such novels salts and compositions in human therapy.
PCT/GB2006/001830 2005-05-28 2006-05-18 Process and novel salt Ceased WO2006129056A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06727135A EP1888606A2 (en) 2005-05-28 2006-05-18 Process and novel salt

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0511000A GB0511000D0 (en) 2005-05-28 2005-05-28 Novel salt
GB0511000.2 2005-05-28
GB0515775A GB0515775D0 (en) 2005-07-30 2005-07-30 Process
GB0515775.5 2005-07-30

Publications (2)

Publication Number Publication Date
WO2006129056A2 WO2006129056A2 (en) 2006-12-07
WO2006129056A3 true WO2006129056A3 (en) 2007-03-29

Family

ID=36932950

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/001830 Ceased WO2006129056A2 (en) 2005-05-28 2006-05-18 Process and novel salt

Country Status (2)

Country Link
EP (1) EP1888606A2 (en)
WO (1) WO2006129056A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2016084A2 (en) 2006-05-11 2009-01-21 Ind-Swift Laboratories Limited Process for the preparation of pure risedronic acid or salts
KR100775440B1 (en) 2006-12-20 2007-11-12 동우신테크 주식회사 Method for preparing risedronate sodium hemipentahydrate
EP2470549B1 (en) * 2009-08-28 2014-07-16 Synthon B.V. Process for making 1-hydroxyalkylidene-1,1-biphosphonic acids

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT47948A (en) * 1986-09-17 1989-04-28 Mta Koezponti Kemiai Kutato In Process for producing poly-(hydroxyphosphonic acids) and their derivatives
WO2001057052A1 (en) * 2000-02-01 2001-08-09 The Procter & Gamble Company Process for making geminal bisphosphonates
EP1243592A2 (en) * 2001-03-19 2002-09-25 Adamed SP. Z O.O. A process for the preparation of risedronic acid
WO2003086355A1 (en) * 2002-04-11 2003-10-23 Teva Pharmaceutical Indudstries, Ltd. Novel polymorphs and pseudopolymorphs of risedronate sodium
US6638920B2 (en) * 2000-07-21 2003-10-28 Merck & Co., Inc. Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses
US20040192655A1 (en) * 2003-01-17 2004-09-30 Revital Lifshitz-Liron Risedronate sodium having a very low content of iron
WO2005066190A1 (en) * 2004-01-02 2005-07-21 Hexal A/S New risedronate salts

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT47948A (en) * 1986-09-17 1989-04-28 Mta Koezponti Kemiai Kutato In Process for producing poly-(hydroxyphosphonic acids) and their derivatives
WO2001057052A1 (en) * 2000-02-01 2001-08-09 The Procter & Gamble Company Process for making geminal bisphosphonates
US6638920B2 (en) * 2000-07-21 2003-10-28 Merck & Co., Inc. Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses
EP1243592A2 (en) * 2001-03-19 2002-09-25 Adamed SP. Z O.O. A process for the preparation of risedronic acid
WO2003086355A1 (en) * 2002-04-11 2003-10-23 Teva Pharmaceutical Indudstries, Ltd. Novel polymorphs and pseudopolymorphs of risedronate sodium
US20040192655A1 (en) * 2003-01-17 2004-09-30 Revital Lifshitz-Liron Risedronate sodium having a very low content of iron
WO2005066190A1 (en) * 2004-01-02 2005-07-21 Hexal A/S New risedronate salts

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Actonel", PACKAGE INSERT TEXT, 1 May 2002 (2002-05-01), XP002314021 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TELEGDI, LASZLO, MRS. ET AL: "Producing poly(hydroxyphosphonic acids) and their derivatives as corrosion inhibitors", XP002398055, retrieved from STN Database accession no. 112:77536 *
STAHL KENNY ET AL: "Ammonium 1-hydroxy-2-(2-pyridinio)ethane-1,1-diyldiphosphonate dihydrate and potassium 1-hydroxy-2-(2-pyridinio)ethane-1,1-diyldipho sphonate dihydrate.", ACTA CRYSTALLOGRAPHICA. SECTION C, CRYSTAL STRUCTURE COMMUNICATIONS. MAR 2006, vol. 62, no. Pt 3, March 2006 (2006-03-01), pages m112 - m115, XP002398012, ISSN: 0108-2701 *

Also Published As

Publication number Publication date
EP1888606A2 (en) 2008-02-20
WO2006129056A2 (en) 2006-12-07

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