[go: up one dir, main page]

WO2006021709A3 - Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules - Google Patents

Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules Download PDF

Info

Publication number
WO2006021709A3
WO2006021709A3 PCT/FR2005/050599 FR2005050599W WO2006021709A3 WO 2006021709 A3 WO2006021709 A3 WO 2006021709A3 FR 2005050599 W FR2005050599 W FR 2005050599W WO 2006021709 A3 WO2006021709 A3 WO 2006021709A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles
solid particle
lipid composition
pharmaceutical composition
anhydrous solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2005/050599
Other languages
English (en)
Other versions
WO2006021709A2 (fr
Inventor
Delphine Marchaud
Pascale Blachez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gattefosse Holding
Original Assignee
Gattefosse Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gattefosse Holding filed Critical Gattefosse Holding
Publication of WO2006021709A2 publication Critical patent/WO2006021709A2/fr
Publication of WO2006021709A3 publication Critical patent/WO2006021709A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Particule anhydre constituée d'un support sur lequel est appliqué un mélange constitué d'au moins un principe actif et d'une composition lipidique auto-émulsionnable, caractérisée en ce que la composition lipidique contient du macrogolglycéride caprylocaprique.
PCT/FR2005/050599 2004-08-05 2005-07-20 Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules Ceased WO2006021709A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0451792 2004-08-05
FR0451792A FR2873923B1 (fr) 2004-08-05 2004-08-05 Particule solide anhydre contenant une composition lipidique liquide et composition pharmaceutique contenant lesdites particules

Publications (2)

Publication Number Publication Date
WO2006021709A2 WO2006021709A2 (fr) 2006-03-02
WO2006021709A3 true WO2006021709A3 (fr) 2006-10-12

Family

ID=34950228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2005/050599 Ceased WO2006021709A2 (fr) 2004-08-05 2005-07-20 Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules

Country Status (2)

Country Link
FR (1) FR2873923B1 (fr)
WO (1) WO2006021709A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110244031A1 (en) * 2010-03-31 2011-10-06 Lifecycle Pharma A/S Porous tablets as carriers for liquid formulations

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059475A1 (fr) * 1999-04-06 2000-10-12 Lipocine, Inc. Compositions et procedes d'administration amelioree d'agents therapeutiques hydrophobes ionisables
WO2001032142A1 (fr) * 1999-11-02 2001-05-10 Cipla Limited Formulation de cyclosporine
WO2003011207A2 (fr) * 2001-07-27 2003-02-13 Gattefosse Holding Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
WO2004000273A1 (fr) * 2002-06-25 2003-12-31 Nicox S.A. Formes pharmaceutiques orales de medicaments liquides a biodisponibilite amelioree
WO2004045586A1 (fr) * 2002-11-15 2004-06-03 Bioserentach Co., Ltd. Preparation solidifiee visant a favoriser l'absorption medicamenteuse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69129918T2 (de) * 1990-03-23 1999-02-04 Yoshitomi Pharmaceutical Industries, Ltd., Osaka Ein in Wasser schwerlösliches Arzneimittel enthaltende pharmazeutische Zubereitung
KR0146671B1 (ko) * 1994-02-25 1998-08-17 김충환 사이클로스포린-함유 분말 조성물
WO2000038655A1 (fr) * 1998-12-23 2000-07-06 Alza Corporation Formes posologiques comprenant des particules poreuses

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059475A1 (fr) * 1999-04-06 2000-10-12 Lipocine, Inc. Compositions et procedes d'administration amelioree d'agents therapeutiques hydrophobes ionisables
WO2001032142A1 (fr) * 1999-11-02 2001-05-10 Cipla Limited Formulation de cyclosporine
WO2003011207A2 (fr) * 2001-07-27 2003-02-13 Gattefosse Holding Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
WO2004000273A1 (fr) * 2002-06-25 2003-12-31 Nicox S.A. Formes pharmaceutiques orales de medicaments liquides a biodisponibilite amelioree
WO2004045586A1 (fr) * 2002-11-15 2004-06-03 Bioserentach Co., Ltd. Preparation solidifiee visant a favoriser l'absorption medicamenteuse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TAKADA, KANJI: "Solidified preparation aiming at promoting drug absorption", XP002394795, retrieved from STN Database accession no. 140:429052 *
ITO Y ET AL: "Oral solid gentamicin preparation using emulsifier and adsorbent", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 105, no. 1-2, 20 June 2005 (2005-06-20), pages 23 - 31, XP004933078, ISSN: 0168-3659 *

Also Published As

Publication number Publication date
WO2006021709A2 (fr) 2006-03-02
FR2873923A1 (fr) 2006-02-10
FR2873923B1 (fr) 2007-01-12

Similar Documents

Publication Publication Date Title
IL245365A0 (en) ATP-linked cassette transport modulators, pharmaceutical preparations containing them and their uses
TW200510002A (en) Solid pharmaceutical preparation
WO2005123076A3 (fr) Compositions pharmaceutiques
WO2006035417A3 (fr) Preparations de dihydropyrimidine
WO2006007448A3 (fr) Compositions pharmaceutiques de co-cristal et methodes d'utilisation associees
AU2003213020A1 (en) Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
WO2007127158A3 (fr) Modification d'absorption percutanée de matériaux topiquement actifs
IL163552A (en) Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the same
AU2003239609A1 (en) 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same
IL218698A0 (en) Compounds that inhibit serine protease activity and pharmaceutical compositions containing the same
ZA200608029B (en) Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs
WO2006099514A3 (fr) Composition d'administration de medicaments contenant un polymere et un agent modificateur
TW200731971A (en) Solid preparation
EP1813611A4 (fr) Composés hétérocycliques azotés substitués en position 1 et ayant un groupe beta-d-glucopyranosyle en position 3 et médicaments contenant ceux-ci
ZA200701443B (en) Pharmaceutical composition in the form of a gastric-resident tablet containing an active principle
WO2007028512A3 (fr) Transfert de principes actifs commande par champ magnetique dans le cadre d'une aerosoltherapie
WO2007005941A3 (fr) Conjugues cibles sur le foie
WO2008078109A3 (fr) Médicament
WO2005074925A8 (fr) Compositions contenant de la piperacilline et du tazobactame
WO2006041538A3 (fr) Melange pour administration transdermique de composes a poids moleculaire faible et eleve
ZA200706160B (en) Pharmaceutically active phosphate binders, their manufactue, compositions containing them and their use
EP1731609A4 (fr) INHIBITEUR DE L'EXPRESSION DE Rad51, MÉDICAMENT CONTENANT L'INHIBITEUR COMME INGRÉDIENT ACTIF ET UTILISATION DE CELUI-CI
WO2006021709A3 (fr) Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules
WO2006109175A3 (fr) Forme posologique solide pour un medicament antidiabetique
WO2006060542A3 (fr) Formulations de benzoxazoles substitues

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase