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WO2006018501A8 - Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques - Google Patents

Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques

Info

Publication number
WO2006018501A8
WO2006018501A8 PCT/FR2005/001853 FR2005001853W WO2006018501A8 WO 2006018501 A8 WO2006018501 A8 WO 2006018501A8 FR 2005001853 W FR2005001853 W FR 2005001853W WO 2006018501 A8 WO2006018501 A8 WO 2006018501A8
Authority
WO
WIPO (PCT)
Prior art keywords
self
lipidic excipients
emulsifying mixtures
galenic
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2005/001853
Other languages
English (en)
Other versions
WO2006018501A1 (fr
Inventor
Jean Pachot
Chicq Serge Segot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2005273839A priority Critical patent/AU2005273839A1/en
Priority to US11/572,402 priority patent/US20080193519A1/en
Priority to CA002579449A priority patent/CA2579449A1/fr
Priority to MX2007001141A priority patent/MX2007001141A/es
Priority to BRPI0513622-9A priority patent/BRPI0513622A/pt
Priority to JP2007521988A priority patent/JP2008508191A/ja
Priority to NZ552715A priority patent/NZ552715A/en
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to EP05790808A priority patent/EP1771154A1/fr
Publication of WO2006018501A1 publication Critical patent/WO2006018501A1/fr
Priority to IL180714A priority patent/IL180714A0/en
Priority to NO20070354A priority patent/NO20070354L/no
Anticipated expiration legal-status Critical
Publication of WO2006018501A8 publication Critical patent/WO2006018501A8/fr
Priority to US12/870,250 priority patent/US20110104268A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention a pour objet de nouvelles formulations galéniques permettant d'améliorer l'absorption intestinale de principes actifs administrés par voie orale, leur procédé de préparation ainsi que l'application d'excipients lipidiques associés à un ou des tensioactifs et un ou des co-tensioactifs pour inhiber les pompes à efflux.
PCT/FR2005/001853 2004-07-20 2005-07-20 Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques Ceased WO2006018501A1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP2007521988A JP2008508191A (ja) 2004-07-27 2005-07-20 脂質賦形剤の自己乳化混合物のガレノス式適用
US11/572,402 US20080193519A1 (en) 2004-07-20 2005-07-20 Galenic Applications of Self-Emulsifying Mixtures of Lipidic Excipients
CA002579449A CA2579449A1 (fr) 2004-07-27 2005-07-20 Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques
MX2007001141A MX2007001141A (es) 2004-07-27 2005-07-20 Aplicaciones galenicas de mezclas auto-emulsionantes de excipientes lipidicos.
BRPI0513622-9A BRPI0513622A (pt) 2004-07-27 2005-07-20 aplicação de combinações auto-emulsificantes (seeds) de excipientes lipìdicos, de surfactantes; composição farmacêutica contendo um princìpio ativo e uma combinação auto-emulsificante (seeds) de excipientes lipìdicos, de surfactantes; e processo para a preparação de combinações auto-emulsificantes (seeds) de excipientes lipìdios, de surfactantes
NZ552715A NZ552715A (en) 2004-07-27 2005-07-20 Galenic applications of self-emulsifying mixtures of lipidic excipients
EP05790808A EP1771154A1 (fr) 2004-07-27 2005-07-20 Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques
AU2005273839A AU2005273839A1 (en) 2004-07-27 2005-07-20 Galenic applications of self-emulsifying mixtures of lipidic excipients
IL180714A IL180714A0 (en) 2004-07-27 2007-01-15 Galenic applications of self-emulsifying mixtures of lipidic excipients
NO20070354A NO20070354L (no) 2004-07-27 2007-01-19 Galeniske anvendelser om selvemulgerende blandinger av lipideksipienter
US12/870,250 US20110104268A1 (en) 2004-07-27 2010-08-27 Galenic applications of self-emulsifying mixtures of lipidic excipients

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0408269A FR2873585B1 (fr) 2004-07-27 2004-07-27 Nouvelles formulations galeniques de principes actifs
FR0408269 2004-07-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/870,250 Continuation US20110104268A1 (en) 2004-07-27 2010-08-27 Galenic applications of self-emulsifying mixtures of lipidic excipients

Publications (2)

Publication Number Publication Date
WO2006018501A1 WO2006018501A1 (fr) 2006-02-23
WO2006018501A8 true WO2006018501A8 (fr) 2007-03-01

Family

ID=34951660

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2005/001853 Ceased WO2006018501A1 (fr) 2004-07-20 2005-07-20 Applications galeniques de melanges auto-emulsionnants d'excipients lipidiques

Country Status (18)

Country Link
US (2) US20080193519A1 (fr)
EP (1) EP1771154A1 (fr)
JP (1) JP2008508191A (fr)
KR (1) KR20070046819A (fr)
CN (1) CN101001608A (fr)
AU (1) AU2005273839A1 (fr)
BR (1) BRPI0513622A (fr)
CA (1) CA2579449A1 (fr)
FR (1) FR2873585B1 (fr)
IL (1) IL180714A0 (fr)
MA (1) MA28748B1 (fr)
MX (1) MX2007001141A (fr)
NO (1) NO20070354L (fr)
NZ (1) NZ552715A (fr)
RU (1) RU2381789C2 (fr)
TW (1) TW200616640A (fr)
WO (1) WO2006018501A1 (fr)
ZA (1) ZA200700553B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1867323A1 (fr) * 2006-06-13 2007-12-19 Farmatron Ltd. Formulations pharmaceutiques avec pénétration améliorée à travers des barrières biologiques
CN101784259B (zh) * 2007-08-21 2013-03-27 巴斯利尔药物股份公司 抗真菌组合物
EP2488022B1 (fr) 2009-10-16 2018-01-10 Mochida Pharmaceutical Co., Ltd. Compositions
JP2013209294A (ja) * 2010-07-30 2013-10-10 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 液状医薬組成物
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (fr) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Préparations et thérapies de substitution pour hormonothérapie naturelle combinée
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
KR101542364B1 (ko) * 2014-10-31 2015-08-07 대화제약 주식회사 탁산을 포함하는 경구 투여용 약학 조성물
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Composition pharmaceutique d'hormone stéroïde
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US20220023314A1 (en) * 2018-12-10 2022-01-27 Halo Science LLC Stable formulations of anesthetics and associated dosage forms
CZ309587B6 (cs) * 2021-01-22 2023-05-03 Oncora S.R.O. Mikroemulzní prekoncentrát s obsahem kladribinu a způsob jeho přípravy
CN114246827B (zh) * 2022-01-04 2023-04-11 中山大学 一种鱼油微乳制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
FR2710535B1 (fr) * 1993-09-30 1995-11-24 Gattefosse Ets Sa Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
EP0933367A1 (fr) * 1997-12-19 1999-08-04 Hoechst Marion Roussel Deutschland GmbH Dérivés d'acylguanidine comme inhibiteurs de résorbtion osseuse et comme antagonistes de récepteur vitronectine
UA63990C2 (uk) * 1998-01-23 2004-02-16 Авентіс Фарма Дойчланд Гмбх Сульфонамідні похідні, спосіб їх одержання та фармацевтична композиція на їх основі
EP1067908B9 (fr) * 1998-04-01 2007-01-24 Jagotec Ag Microemulsions a base de taxane
CA2302735A1 (fr) * 1998-07-14 2000-01-27 Em Industries, Inc. Systemes d'apport de medicaments par microdispersion
GB0003685D0 (en) * 2000-02-17 2000-04-05 Univ Cardiff Sensitisation of cellular material
FR2818905A1 (fr) * 2000-12-28 2002-07-05 Cll Pharma Compositions pharmaceutiques colloidales micellaires renfermant un principe actif lipophile
FR2827770B1 (fr) * 2001-07-27 2005-08-19 Gattefosse Ets Sa Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
WO2003045357A1 (fr) * 2001-11-27 2003-06-05 Transform Pharmaceuticals, Inc. Formules pharmaceutiques orales contenant du paclitaxel et des derives, et methodes d'administration de celles-ci
US7524861B2 (en) * 2002-05-14 2009-04-28 David Frank Hayman Process for the preparation of a hydrate of an anthranilic acid derivative

Also Published As

Publication number Publication date
EP1771154A1 (fr) 2007-04-11
NZ552715A (en) 2010-12-24
AU2005273839A1 (en) 2006-02-23
NO20070354L (no) 2007-04-17
CN101001608A (zh) 2007-07-18
RU2007107199A (ru) 2008-09-10
MA28748B1 (fr) 2007-07-02
BRPI0513622A (pt) 2008-05-13
US20110104268A1 (en) 2011-05-05
US20080193519A1 (en) 2008-08-14
IL180714A0 (en) 2007-06-03
CA2579449A1 (fr) 2006-02-23
WO2006018501A1 (fr) 2006-02-23
MX2007001141A (es) 2007-04-19
RU2381789C2 (ru) 2010-02-20
KR20070046819A (ko) 2007-05-03
JP2008508191A (ja) 2008-03-21
FR2873585B1 (fr) 2006-11-17
ZA200700553B (en) 2008-05-28
FR2873585A1 (fr) 2006-02-03
TW200616640A (en) 2006-06-01

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