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WO2006018043A3 - Valve slider for a microfluidic coupling device - Google Patents

Valve slider for a microfluidic coupling device Download PDF

Info

Publication number
WO2006018043A3
WO2006018043A3 PCT/EP2004/051833 EP2004051833W WO2006018043A3 WO 2006018043 A3 WO2006018043 A3 WO 2006018043A3 EP 2004051833 W EP2004051833 W EP 2004051833W WO 2006018043 A3 WO2006018043 A3 WO 2006018043A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupling device
microfluidic coupling
slider
valve slider
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/051833
Other languages
French (fr)
Other versions
WO2006018043A2 (en
Inventor
Manfred Berndt
Thomas Reinhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Inc
Original Assignee
Agilent Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Inc filed Critical Agilent Technologies Inc
Priority to DE112004002936T priority Critical patent/DE112004002936B4/en
Priority to PCT/EP2004/051833 priority patent/WO2006018043A2/en
Priority to DE112004003058T priority patent/DE112004003058B4/en
Publication of WO2006018043A2 publication Critical patent/WO2006018043A2/en
Anticipated expiration legal-status Critical
Publication of WO2006018043A3 publication Critical patent/WO2006018043A3/en
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0011—Gate valves or sliding valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0013—Rotary valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0042—Electric operating means therefor
    • F16K99/0046—Electric operating means therefor using magnets
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0042—Electric operating means therefor
    • F16K99/0048—Electric operating means therefor using piezoelectric means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/008—Multi-layer fabrications
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Multiple-Way Valves (AREA)
  • Micromachines (AREA)
  • Quick-Acting Or Multi-Walled Pipe Joints (AREA)

Abstract

A valve slider (1;35;53;65;79;97) for a microfluidic coupling device (63;77;95). The slider comprises a flat foil and is adapted for flow-controlling the flow within at least one flow path (5,7) of the microfluidic coupling device (63;77;95). The slider slides relatively to the microfluidic coupling device (63;77;95). The slider has at least one control element (3; 13) and controls the flow within the flow path (5,7).
PCT/EP2004/051833 2004-08-18 2004-08-18 Valve slider for a microfluidic coupling device Ceased WO2006018043A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE112004002936T DE112004002936B4 (en) 2004-08-18 2004-08-18 Microfluidic arrangement with a valve slide for a microfluidic coupling device
PCT/EP2004/051833 WO2006018043A2 (en) 2004-08-18 2004-08-18 Valve slider for a microfluidic coupling device
DE112004003058T DE112004003058B4 (en) 2004-08-18 2004-08-18 Microfluidic coupling device with variable flow resistance and microfluidic arrangement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2004/051833 WO2006018043A2 (en) 2004-08-18 2004-08-18 Valve slider for a microfluidic coupling device

Publications (2)

Publication Number Publication Date
WO2006018043A2 WO2006018043A2 (en) 2006-02-23
WO2006018043A3 true WO2006018043A3 (en) 2007-04-19

Family

ID=35907774

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/051833 Ceased WO2006018043A2 (en) 2004-08-18 2004-08-18 Valve slider for a microfluidic coupling device

Country Status (2)

Country Link
DE (2) DE112004002936B4 (en)
WO (1) WO2006018043A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009015395B4 (en) 2009-03-23 2022-11-24 Thinxxs Microtechnology Gmbh Flow cell for treating and/or examining a fluid
US20140345372A1 (en) 2012-02-01 2014-11-27 Waters Technologies Corporation Managing fluidic connections to microfluidic devices

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045661A1 (en) * 1996-05-23 1997-12-04 Amersham Pharmacia Biotech Ab Valve, adapted to connect a flow module to a flow line
US20020155032A1 (en) * 2001-02-09 2002-10-24 Shaorong Liu Method and apparatus for reproducible sample injection on microfabricated devices
US20040119070A1 (en) * 2002-08-02 2004-06-24 Roach David John Integrated microchip design

Family Cites Families (23)

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US3964513A (en) * 1975-04-08 1976-06-22 Hoffmann-La Roche Inc. Rotating sampling valve
DE2704869C3 (en) * 1977-02-05 1980-11-20 Festo-Maschinenfabrik Gottlieb Stoll, 7300 Esslingen In a modular design, fluidic control circuit composed of the same assemblies containing logic circuit elements
US4445391A (en) * 1981-10-19 1984-05-01 Coulter Electronics, Inc. Liquid metering and transfer valve assembly
DE3565986D1 (en) * 1984-05-02 1988-12-08 Brendan James Hamill An apparatus for the chemical synthesis of oligonucleotides
CA1304916C (en) * 1984-10-18 1992-07-14 Wilhelm Bannwarth Apparatus for the parallel performance of a plurality of chemical reaction sequences
DE3813671A1 (en) * 1988-04-22 1989-11-02 Europ Lab Molekularbiolog DEVICE FOR CARRYING OUT CHEMICAL REACTIONS
DE3917396A1 (en) * 1989-05-29 1990-12-06 Buerkert Gmbh MICRO VALVE
DE4029746A1 (en) * 1990-09-20 1992-04-02 Joachim Hermann Dr Med Lehner DEVICE AND METHOD FOR THE SIMULTANEOUS MEASUREMENT OF DIFFERENT PHYSICAL AND CHEMICAL PARAMETERS OF A LIQUID
DE4041579A1 (en) * 1990-12-22 1992-06-25 Bosch Gmbh Robert MICRO VALVE
US5254313A (en) * 1991-04-24 1993-10-19 Toa Medical Electronics Co., Ltd. Apparatus for diluting and mixing a liquid specimen
JP3077772B2 (en) * 1991-06-05 2000-08-14 シスメックス株式会社 Automatic particle analysis method and apparatus using a plurality of analysis modules
JP3043498B2 (en) * 1991-11-20 2000-05-22 シスメックス株式会社 Sample analyzer
DE4206488C2 (en) * 1992-03-02 1993-12-23 Deutsches Krebsforsch Device for carrying out chemical reactions taking place simultaneously or sequentially
JP2589997Y2 (en) * 1993-02-17 1999-02-03 シスメックス株式会社 Sampling valve
US5655568A (en) * 1995-08-08 1997-08-12 Bhargava; Raj Passive flow regulating device
US5964239A (en) * 1996-05-23 1999-10-12 Hewlett-Packard Company Housing assembly for micromachined fluid handling structure
JP3984748B2 (en) * 1999-03-17 2007-10-03 株式会社日立製作所 Chemical analyzer and chemical analysis system
US6845962B1 (en) * 2000-03-22 2005-01-25 Kelsey-Hayes Company Thermally actuated microvalve device
US6702256B2 (en) * 2001-07-17 2004-03-09 Agilent Technologies, Inc. Flow-switching microdevice
ATE338298T1 (en) * 2001-07-31 2006-09-15 Kelsey Hayes Co MICROMECHANICAL STRUCTURE USABLE IN A MICROVALVE FOR PRESSURE CONTROL AND IN A PROPORTIONAL MICROVALVE
DE10222478A1 (en) * 2002-05-22 2003-12-04 Bartels Mikrotechnik Gmbh Microchip based analytical device can undertake e.g. liquid separation from a gas by movement of a flexible layer overlying a recess in the chip surface
EP1536228A1 (en) * 2003-11-27 2005-06-01 Agilent Technologies, Inc. Dual loop autosampling
DE602004004612T2 (en) * 2004-05-22 2007-05-24 Agilent Technologies, Inc. (n.d. Ges. d. Staates Delaware), Santa Clara Component of a microfluidic valve

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045661A1 (en) * 1996-05-23 1997-12-04 Amersham Pharmacia Biotech Ab Valve, adapted to connect a flow module to a flow line
US20020155032A1 (en) * 2001-02-09 2002-10-24 Shaorong Liu Method and apparatus for reproducible sample injection on microfabricated devices
US20040119070A1 (en) * 2002-08-02 2004-06-24 Roach David John Integrated microchip design

Also Published As

Publication number Publication date
DE112004003058B4 (en) 2009-05-07
DE112004002936B4 (en) 2008-12-11
DE112004002936T5 (en) 2007-12-13
WO2006018043A2 (en) 2006-02-23

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