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WO2006017627A3 - Compositions dietetiques et procedes d'utilisation dans le traitement de l'insulinoresistance - Google Patents

Compositions dietetiques et procedes d'utilisation dans le traitement de l'insulinoresistance Download PDF

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Publication number
WO2006017627A3
WO2006017627A3 PCT/US2005/027668 US2005027668W WO2006017627A3 WO 2006017627 A3 WO2006017627 A3 WO 2006017627A3 US 2005027668 W US2005027668 W US 2005027668W WO 2006017627 A3 WO2006017627 A3 WO 2006017627A3
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WO
WIPO (PCT)
Prior art keywords
acid
insulin resistance
treating insulin
dietary compositions
docosahexaenoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/US2005/027668
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English (en)
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WO2006017627A2 (fr
Inventor
Barry Sears
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Publication of WO2006017627A2 publication Critical patent/WO2006017627A2/fr
Publication of WO2006017627A3 publication Critical patent/WO2006017627A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne des formulations de compléments alimentaires, ainsi que des procédés d'administration de ces compléments pour modifier le taux d'insuline, pour traiter l'insulinorésistance, et/ou pour traiter l'obésité chez un patient. Les compléments alimentaires contiennent: (a) l'acide docosahexanoïque (DHA), (b) l'acide eicosapentanoïque (EPA) et (c) éventuellement, un inhibiteur spécifique de l'enzyme Δ-5 désaturase (D5D).
PCT/US2005/027668 2004-08-06 2005-08-04 Compositions dietetiques et procedes d'utilisation dans le traitement de l'insulinoresistance Ceased WO2006017627A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59979304P 2004-08-06 2004-08-06
US60/599,793 2004-08-06

Publications (2)

Publication Number Publication Date
WO2006017627A2 WO2006017627A2 (fr) 2006-02-16
WO2006017627A3 true WO2006017627A3 (fr) 2006-04-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/027668 Ceased WO2006017627A2 (fr) 2004-08-06 2005-08-04 Compositions dietetiques et procedes d'utilisation dans le traitement de l'insulinoresistance

Country Status (1)

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WO (1) WO2006017627A2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9066915B2 (en) 2006-10-03 2015-06-30 Michael D. Myers Meal replacement compositions and weight control method
US9138415B2 (en) 2009-04-29 2015-09-22 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2010028067A1 (fr) 2008-09-02 2010-03-11 Amarin Corporation Plc Composition pharmaceutique comprenant de l'acide eïcosapentaénoïque et de l'acide nicotinique et ses procédés d'utilisation
EP4008327A1 (fr) 2009-04-29 2022-06-08 Amarin Pharmaceuticals Ireland Limited Compositions pharmaceutiques comprenant de l'epa et un agent cardiovasculaire et leurs procédés d'utilisation
NZ597193A (en) 2009-06-15 2014-01-31 Amarin Pharmaceuticals Ie Ltd Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
ES2554657T3 (es) 2009-09-23 2015-12-22 Amarin Pharmaceuticals Ireland Limited Composición farmacéutica que comprende ácido graso omega-3 y derivado hidroxi de una estatina y métodos de uso de la misma
WO2012074930A2 (fr) 2010-11-29 2012-06-07 Amarin Pharma, Inc. Composition à faible éructation et méthodes de traitement et/ou de prévention de maladie cardiovasculaire chez un sujet présentant une allergie/hypersensibilité aux poissons
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
WO2013070735A1 (fr) 2011-11-07 2013-05-16 Amarin Pharmaceuticals Ireland Limited Méthodes de traitement de l'hypertriglycéridémie
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
AU2013207368A1 (en) 2012-01-06 2014-07-24 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-CRP) in a subject
NZ737380A (en) 2012-06-29 2019-05-31 Amarin Pharmaceuticals Ie Ltd Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
RU2020125675A (ru) * 2012-06-29 2020-09-16 Амарин Фармасьютикалз Айрлэнд Лимитед Способы лечения педиатрического метаболического синдрома
US20150265566A1 (en) 2012-11-06 2015-09-24 Amarin Pharmaceuticals Ireland Limited Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US11109607B2 (en) 2013-11-18 2021-09-07 Gary Hall Oil-based compositions for enhancing oral health and general wellness in humans
JP2017515884A (ja) * 2014-03-13 2017-06-15 バリー ディー. シアーズ, 低レベルの慢性炎症を低減するための組成物および方法
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
CA2990140A1 (fr) * 2015-06-26 2016-12-29 Pronova Biopharma Norge As Composition pour le traitement de la nafld
CA2995249A1 (fr) * 2015-08-14 2017-02-23 Barry D. Sears Materiaux et procedes de modulation de la resistance a l'insuline et des hormones intestinales a l'aide de produits alimentaires composites
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
EP3251516A1 (fr) * 2016-05-30 2017-12-06 Instituto Nacional de Medicina Genomica (INMEGEN) Composition nutritionnelle
EP3251667A1 (fr) * 2016-05-30 2017-12-06 Instituto Nacional de Medicina Genomica (INMEGEN) Composition nutritionnelle
WO2018213663A1 (fr) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions et méthodes pour dimunuer les triglycérides chez un sujet ayant une fonction rénale réduite
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
CN111991386A (zh) 2018-09-24 2020-11-27 阿马里纳药物爱尔兰有限公司 降低受试者的心血管事件的风险的方法
CN116350616A (zh) 2019-11-12 2023-06-30 阿马里纳药物爱尔兰有限公司 降低心房纤颤和/或心房扑动受试者心血管事件风险的方法
KR20240012390A (ko) 2021-04-21 2024-01-29 애머린 파마슈티칼스 아일랜드 리미티드 심부전의 위험을 감소시키는 방법

Citations (5)

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EP0302481A2 (fr) * 1987-08-07 1989-02-08 Century Laboratories Inc. Utilisation d'acides gras libres pour la fabrication d'un médicament pour le traitement du diabète mellitus
DE19503993A1 (de) * 1995-02-08 1996-08-14 Johann Friedrich Dr Med Desaga Verwendung eines Produktes zur enteralen Versorgung mit Lebensmittelinhaltsstoffen oder Arzneimittelinhaltsstoffen
WO2004082402A1 (fr) * 2003-03-18 2004-09-30 Novartis Ag Compositions comprenant des acides gras et des acides amines
WO2004093869A1 (fr) * 2003-04-18 2004-11-04 Zone Enterprises, Inc. Compositions alimentaires permettant de reduire une inflammation
WO2005060954A1 (fr) * 2003-12-19 2005-07-07 Pronova Biocare As Utilisation d'une composition d'acides gras comprenant au moins un epa et un dha ou des combinaisons de ceux-ci

Patent Citations (5)

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EP0302481A2 (fr) * 1987-08-07 1989-02-08 Century Laboratories Inc. Utilisation d'acides gras libres pour la fabrication d'un médicament pour le traitement du diabète mellitus
DE19503993A1 (de) * 1995-02-08 1996-08-14 Johann Friedrich Dr Med Desaga Verwendung eines Produktes zur enteralen Versorgung mit Lebensmittelinhaltsstoffen oder Arzneimittelinhaltsstoffen
WO2004082402A1 (fr) * 2003-03-18 2004-09-30 Novartis Ag Compositions comprenant des acides gras et des acides amines
WO2004093869A1 (fr) * 2003-04-18 2004-11-04 Zone Enterprises, Inc. Compositions alimentaires permettant de reduire une inflammation
WO2005060954A1 (fr) * 2003-12-19 2005-07-07 Pronova Biocare As Utilisation d'une composition d'acides gras comprenant au moins un epa et un dha ou des combinaisons de ceux-ci

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DELARUE JACQUES ET AL: "n-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity?", REPRODUCTION NUTRITION DEVELOPMENT, vol. 44, no. 3, May 2004 (2004-05-01), pages 289 - 299, XP002365756, ISSN: 0926-5287 *
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9066915B2 (en) 2006-10-03 2015-06-30 Michael D. Myers Meal replacement compositions and weight control method
US9138415B2 (en) 2009-04-29 2015-09-22 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9585856B2 (en) 2009-04-29 2017-03-07 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy

Also Published As

Publication number Publication date
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