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WO2006010077A3 - Prodrugs of lonidamine and lonidamine analogs - Google Patents

Prodrugs of lonidamine and lonidamine analogs Download PDF

Info

Publication number
WO2006010077A3
WO2006010077A3 PCT/US2005/024434 US2005024434W WO2006010077A3 WO 2006010077 A3 WO2006010077 A3 WO 2006010077A3 US 2005024434 W US2005024434 W US 2005024434W WO 2006010077 A3 WO2006010077 A3 WO 2006010077A3
Authority
WO
WIPO (PCT)
Prior art keywords
lonidamine
prodrugs
analogs
methods
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/024434
Other languages
French (fr)
Other versions
WO2006010077A2 (en
Inventor
Mark Matteucci
Harold E Selick
Photon Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Templates Inc
Original Assignee
Threshold Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Threshold Pharmaceuticals Inc filed Critical Threshold Pharmaceuticals Inc
Publication of WO2006010077A2 publication Critical patent/WO2006010077A2/en
Publication of WO2006010077A3 publication Critical patent/WO2006010077A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides prodrugs of lonidamine and lonidamine analogs as well as methods of using such prodrugs.
PCT/US2005/024434 2004-07-08 2005-07-08 Prodrugs of lonidamine and lonidamine analogs Ceased WO2006010077A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58693404P 2004-07-08 2004-07-08
US60/586,934 2004-07-08
US62450504P 2004-11-01 2004-11-01
US60/624,505 2004-11-01

Publications (2)

Publication Number Publication Date
WO2006010077A2 WO2006010077A2 (en) 2006-01-26
WO2006010077A3 true WO2006010077A3 (en) 2006-08-31

Family

ID=35785776

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/024434 Ceased WO2006010077A2 (en) 2004-07-08 2005-07-08 Prodrugs of lonidamine and lonidamine analogs

Country Status (1)

Country Link
WO (1) WO2006010077A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015002996A1 (en) * 2013-07-01 2015-01-08 University Of Georgia Research Foundation, Inc. Precise delivery of therapeutic agents to cell mitochondria for anti-cancer therapy
EP3564214B1 (en) 2018-05-04 2024-07-03 Universita' Degli Studi G. D'annunzio Chieti - Pescara Indazole derivatives as modulators of the cannabinoid system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895026A (en) * 1972-02-29 1975-07-15 Acraf Substituted 1-benzyl-1h-indazole-3-carboxylic acids and derivatives thereof
US5260327A (en) * 1985-10-02 1993-11-09 Sloan-Kettering Institute For Cancer Research Methods for inhibiting the proliferation of brain and hepatic metastases by using lonidamine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895026A (en) * 1972-02-29 1975-07-15 Acraf Substituted 1-benzyl-1h-indazole-3-carboxylic acids and derivatives thereof
US5260327A (en) * 1985-10-02 1993-11-09 Sloan-Kettering Institute For Cancer Research Methods for inhibiting the proliferation of brain and hepatic metastases by using lonidamine

Also Published As

Publication number Publication date
WO2006010077A2 (en) 2006-01-26

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