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WO2006010051A3 - Methods of diagnosing & treating diabetes and insulin resistance - Google Patents

Methods of diagnosing & treating diabetes and insulin resistance Download PDF

Info

Publication number
WO2006010051A3
WO2006010051A3 PCT/US2005/024365 US2005024365W WO2006010051A3 WO 2006010051 A3 WO2006010051 A3 WO 2006010051A3 US 2005024365 W US2005024365 W US 2005024365W WO 2006010051 A3 WO2006010051 A3 WO 2006010051A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
diagnosing
insulin resistance
treating diabetes
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/024365
Other languages
French (fr)
Other versions
WO2006010051A2 (en
Inventor
Shonna A Moodie
Grace Perez
Fang Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CymaBay Therapeutics Inc
Original Assignee
Metabolex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolex Inc filed Critical Metabolex Inc
Priority to JP2007520559A priority Critical patent/JP2008505648A/en
Publication of WO2006010051A2 publication Critical patent/WO2006010051A2/en
Anticipated expiration legal-status Critical
Publication of WO2006010051A3 publication Critical patent/WO2006010051A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides compositions and methods for diagnosing and treating diabetes and insulin resistance. In particular, the invention provides methods of identifying modulators of the polynucleotides or polypeptides of the invention and using those modulators to treat diabetes, as well as methods of diagnosing diabetes by measuring the levels of the polynucleotides or polypeptides of the invention in a patient.
PCT/US2005/024365 2004-07-07 2005-07-07 Methods of diagnosing & treating diabetes and insulin resistance Ceased WO2006010051A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007520559A JP2008505648A (en) 2004-07-07 2005-07-07 Methods for diagnosis and treatment of diabetes and insulin resistance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58635804P 2004-07-07 2004-07-07
US60/586,358 2004-07-07

Publications (2)

Publication Number Publication Date
WO2006010051A2 WO2006010051A2 (en) 2006-01-26
WO2006010051A3 true WO2006010051A3 (en) 2007-02-22

Family

ID=35785769

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/024365 Ceased WO2006010051A2 (en) 2004-07-07 2005-07-07 Methods of diagnosing & treating diabetes and insulin resistance

Country Status (2)

Country Link
JP (1) JP2008505648A (en)
WO (1) WO2006010051A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522667D0 (en) 2015-12-22 2016-02-03 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
SG10202111399YA (en) 2015-12-22 2021-11-29 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811242A (en) * 1995-10-24 1998-09-22 Tokuyama Corporation Marker and reagent for diabetes mellitus and diabetes mellitus complication
US6074822A (en) * 1995-11-03 2000-06-13 Board Of Trustees Operating Michigan State University Method for testing for risk of diabetes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811242A (en) * 1995-10-24 1998-09-22 Tokuyama Corporation Marker and reagent for diabetes mellitus and diabetes mellitus complication
US6074822A (en) * 1995-11-03 2000-06-13 Board Of Trustees Operating Michigan State University Method for testing for risk of diabetes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WILKIN T. ET AL.: "Markers for insulin dependent diabetes: towards early detection", BRIT. MED. J., vol. 293, 22 November 1986 (1986-11-22), pages 1323 - 1326, XP003008378 *

Also Published As

Publication number Publication date
WO2006010051A2 (en) 2006-01-26
JP2008505648A (en) 2008-02-28

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