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WO2006092367A1 - Procede et dispositif pour steriliser la surface d'objets - Google Patents

Procede et dispositif pour steriliser la surface d'objets Download PDF

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Publication number
WO2006092367A1
WO2006092367A1 PCT/EP2006/060126 EP2006060126W WO2006092367A1 WO 2006092367 A1 WO2006092367 A1 WO 2006092367A1 EP 2006060126 W EP2006060126 W EP 2006060126W WO 2006092367 A1 WO2006092367 A1 WO 2006092367A1
Authority
WO
WIPO (PCT)
Prior art keywords
catalyst
sterilizing agent
objects
applicator
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/060126
Other languages
German (de)
English (en)
Inventor
Hanno Geissler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIG Services AG
Original Assignee
SIG Technology AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SIG Technology AG filed Critical SIG Technology AG
Publication of WO2006092367A1 publication Critical patent/WO2006092367A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases

Definitions

  • the invention relates to a method for sterilizing the surface of objects.
  • the invention further relates to a device for sterilizing the surface of objects, in particular of packaging material or the like, with a supply device, an application device and a transport device, wherein the supply device is arranged upstream of the application device for supplying a sterilization agent, wherein the application device has an outlet for applying the Having sterilizing agent on the objects and wherein the transport device is provided for supplying the objects to be sterilized.
  • sterilizing agents in this context are understood to mean only chemically acting sterilants. These react with adhering to the surfaces to be sterilized bacterial cells, germs, spores or the like, whereby these microorganisms are killed.
  • hydrogen peroxide the killing of the microorganisms is essentially due to the property of the hydrogen peroxide to oxidize organic compounds.
  • a device and a method for the sterilization of packaging materials using a liquid sterilizing agent is known.
  • the known device interacts with a packaging machine and has a supply device, the conditioning and the supply of the
  • Sterilization agent is used to an applicator.
  • a mixing chamber is provided, which is fed via a compressor and a pump with air and sterilizing agent.
  • Sterilization agent is preferably an aqueous hydrogen peroxide solution.
  • a portion of the supplied air flow is supplied together with the sterilizing agent to a nozzle to achieve a fine atomization, while the other part of the air flow is guided via a heater for heating the air flow.
  • the mixture of sterilizing agent and air conditioned in the mixing chamber is forwarded to the application device with which the mixture is finally applied to a packaging material web.
  • the packaging material web is passed by means of a transport device continuously at the applicator.
  • the sterilant is applied at a temperature higher than the packaging material. Due to this, on the one hand there is a condensation and uniform distribution of the sterilizing agent on the surface of the packaging material and on the other hand to a heating of the packaging material. By heating the packaging material, the subsequent drying of the packaging material or removal of sterilizing agent is simplified. For example, cold, sterile air can be used for drying.
  • a disadvantage of this and other methods known from the prior art is that the handling and the conditioning of the sterilizing agent used are mature and therefore no appreciable increases in the sterilization effect are possible by known methods. This leads to an increased need for sterilants and thus ultimately to increased costs. In addition, the use of high volumes of sterilizing agents also attacks machine parts, significantly reducing their service life. This can be observed especially when using hydrogen peroxide-containing sterilants.
  • the object of the present invention is therefore to design and further develop the method mentioned above and the method described in more detail above, and the corresponding device for carrying out the method, in order to achieve a more efficient use of the sterilizing agent.
  • the above object is achieved in a method for sterilizing the surface of objects, in particular of packaging material or the like, that in
  • a sterilization agent is supplied to an application device by a supply device, in a second step the sterilization agent supplied to the application device is brought into contact with a catalyst and activated, and in a third step the activated sterilization agent is applied to the surface of the objects to be sterilized becomes.
  • Applicator having a catalyst for activating the sterilizing agent.
  • the invention is based on the idea of catalytically activating the sterilant or increasing the reactivity of the sterilant by the catalytic conversion of individual molecules or compounds of the sterilant, thereby improving the sterilization result.
  • the required amount of sterilant or, if it contains other components in addition to the actual active ingredient the required amount of active ingredient can be reduced.
  • the sterilant and the active ingredient are distinct from the context.
  • Another essential basic idea in connection with the invention is the activation of the sterilizing agent and the application of the sterilizing agent as far as possible in one process step or at least in two directly
  • the activation is by no means bound to the applicator and can also be activated before the applicator approximately in a mixing chamber or the like.
  • the activity of the sterilant on the object to be sterilized is essential to the result of the sterilization, it would be inconvenient to perform the activation too early, so that the activity again drops noticeably until the sterilant hits the surface of the objects.
  • the activated sterilizing agent can in principle be applied in the form of small drops, as a vapor or as a mixed form in order to achieve the best possible sterilization result. It is understood in this context that the invention is basically applicable to all known from the prior art method of the type mentioned.
  • the special configuration of the conditioning and the application of the sterilizing agent is therefore in principle not critical to the invention, even if this can result in significant differences in terms of the resulting from the invention increase in efficiency.
  • the types of conditioning and application are preferred, which already without the use of a catalyst have preferred properties and are in principle extendable by a catalytic step.
  • the invention is not limited only to sterilization (killing of microorganisms) but may also be used for disinfection (inactivation of microorganisms) or the like.
  • Activation of the sterilizing agent in connection with the invention means the formation of intermediates (intermediates). Since the catalyst preferably has no contact with the surface to be sterilized, the intermediates are preferably intermediates involved in the oxidation of organic compounds on the surface of the objects. As a sterilizing agent thus come into consideration in principle all compounds and mixtures that can be catalytically at least partially converted to such intermediates or intermediates.
  • radicals are particularly preferred.
  • Another advantage of radicals is that the number of radicals decreases rapidly after their formation. This is particularly due to radical addition reactions of two radicals, which do not lead to the formation of new radicals. The increased reactivity of the activated sterilant thus holds at best just as long as necessary for the sterilization or the
  • Sterilization agent has contact with the surface to be sterilized. Immediately thereafter, there are no or at least significantly fewer compounds with one
  • TH / bs 041592WO increased reactivity, could be affected by the personnel or machine parts.
  • the sterilizing agent is heated by the catalyst before activation.
  • the catalytic activation is accelerated and, on the other hand, the reactivity of the sterilizing agent or the speed of the sterilization processes taking place is increased. Basically, the better it is, the cheaper it is
  • Sterilization agent is heated. From a structural and apparative point of view, however, a temperature between about 100 0 C and 35O 0 C, in particular between 200 0 C and 300 0 C is preferred. If the sterilization agent is warmer than the supplied objects, the packaging can also be dried after sterilization without excessive expense with cold air or another, preferably inert, gas. It is particularly preferred, on the one hand, for the sterilizing agent during the sterilization process
  • TH / bs 041592WO Take over carrier medium and on the other hand act as a kind of reagent for promoting the individual running chemical reactions. It is thus possible, for example, to influence the location of specific chemical or thermodynamic equilibria through the use of gases.
  • the gas stream can also be used to introduce energy through an upstream heating. It is understood in this context that instead of a gas, a mixture of gases can be used. In a simple case, this is air, which may have been self-sterilized before use. It is further understood that the gas stream may also serve to mix the components, formulate a particular flow state, promote media, and establish good contact between the sterilant and the catalyst.
  • a good distribution and high efficiency of the sterilant used can be achieved when the sterilant is sprayed onto the surfaces to be sterilized by means of a nozzle. It is basically independent whether the sterilant is applied liquid or as a vapor, but steam is preferred.
  • TH / bs 041592WO can end immediately after the release of the sterilant to ensure high reactivity.
  • the device according to the invention makes it possible to carry out the method according to the invention and is based on the idea of providing a catalyst by means of which the sterilizing agent is forcibly and immediately activated before being applied to the surface to be sterilized.
  • an applicator is provided which has a catalyst in the region of the outlet.
  • all known from the prior art devices in question which are suitable for contactless application of the sterilizing agent on the surfaces to be sterilized are suitable as application devices.
  • the application device may also merely be an open pipe end or the like. It is understood, however, that nozzles such as atomizing nozzles or the like are particularly preferred as the application device. This is especially true when a liquid sterilant is to be applied.
  • Transport device provided.
  • the transport device is preferably designed such that the applicator arranged substantially stationary
  • TH / bs 041592WO is and the objects whose surfaces are to be sterilized, are moved by the transport device to the applicator.
  • the invention is not limited to such a design, but also includes such
  • the catalytically active component of the catalyst is platinum, palladium, iridium, rhodium, ruthenium or manganese dioxide.
  • the catalyst preferably comprises a support material (eg Al 2 O 3 ). In principle, however, it is also possible to dispense with such a carrier material.
  • the catalyst is arranged in the interior of the application device, preferably in the interior of a nozzle channel of the application device designed as a nozzle.
  • the catalyst forms part of the wall of the channel of the applicator or the nozzle channel. In this way, the sterilant flowing through the channel to the outlet forcibly contacts the catalyst.
  • the catalyst is annular or designed as a hollow cylinder to keep the design effort low.
  • the channel of the applicator should be formed at least partially concentric with the catalyst. It is understood in this connection that the catalyst can taper to one side in order to be usable in the region of the outlet of the application device, which is preferably designed as a nozzle.
  • the active component can also be applied directly to the wall of the channel of the applicator.
  • the catalyst downstream of the outlet of the applicator ie outside the actual applicator or the actual nozzle channel
  • the catalyst is arranged and designed such that it is flown by the exiting sterilizing agent.
  • the catalyst is designed in the form of a wire, finger, hook or the like. Further, it is useful if the catalyst is curved, bent or otherwise shaped and thus extends from a fastener or the like in front of the outlet.
  • the catalyst has a plurality of openings through which the sterilizing agent can flow in the direction of the surface to be sterilized.
  • the catalyst may be formed as a network, which is arranged in front of the outlet of the nozzle.
  • the catalyst can be a heating device for at least
  • TH / bs 041592WO be preceded by partial heating and / or evaporation of the sterilant.
  • the required heating power can be applied without further ado, it may be favorable from a constructive as well as a procedural point of view if the catalyst can be heated directly or indirectly.
  • an electric heater is recommended, wherein the catalyst itself can serve as a heating resistor.
  • the supply device can also be designed to supply gases.
  • gases a mixture of sterilant and gas is supplied to the catalyst and possibly also the heater.
  • the gas or different gases can also be mixed directly in the nozzle with the sterilizing agent to ensure a fine atomizing of the sterilizing agent.
  • evaporation both stands for evaporation of the sterilizing agent in the supply device or in the application device as well as for evaporation after leaving the application device as a result of a pressure reduction. Which alternative is preferred in an individual case depends on the
  • the parameters temperature, volume flow of the sterilizing agent and possibly the gas, type of sterilizing agent, flow rate and the like can be selected so that the best possible sterilization process can be achieved can.
  • FIG. 1 shows a device according to the invention in a schematic side view
  • Fig. 2 shows a first preferred embodiment of the nozzle of FIG. 1 in vertical section
  • Fig. 3 shows a second preferred embodiment of the nozzle of Fig. 1 in vertical section.
  • the device 1 shows a preferred exemplary embodiment of the device 1 according to the invention, which comprises a supply device 2, an application device 3 designed as a nozzle, and a transport device 4.
  • the supply device 2 are associated with supply lines for supplying a sterilizing agent S and air L.
  • the sterilizing agent S and air L are associated with supply lines for supplying a sterilizing agent S and air L.
  • Supply device 2 is still a heater 5, by means of which the supplied mixture of sterilant S and air L can be heated.
  • the heater 5 is designed such that the mixture of sterilant S and air L is heated so strongly at sufficiently high heat output that a part of the sterilant S evaporates at the latest after leaving the applicator 3.
  • the mixture of sterilant S and air L is then fed to the applicator 3, in which a catalyst 5 is located.
  • the application device 3 is ultimately an activation device designed as a nozzle.
  • the mixture of sterilant S and air L has passed past the catalyst 5, it is applied to the surfaces of the objects 7 to be sterilized.
  • the objects 7 are supplied via the transport device 4.
  • the objects 7 can also be blanks of a packaging material, a packaging material web, packages open at the top or the like.
  • the applicator is placed over or dipped in the package. Then the sterilizing agent is sprayed on the insides and optionally subsequently expelled again by a sterile purge air.
  • a sterile purge air One speaks in this context of drying.
  • the applicator 3 formed as a nozzle of the device 1 of Fig. 1 is shown in vertical section.
  • the nozzle has a channel 10 tapering to the outlet 9.
  • an annular groove is provided, in which the
  • TH / bs 041592WO likewise annular catalyst 6 is seated.
  • the compressed mixture of sterilant S and air L is relaxed, wherein the sterilizing agent S in the form of fine droplets or, if the temperature of the mixture at the outlet 9 is high enough, in the form of vapor is applied to the surface of an object 7.
  • the vapor condenses at least partially or briefly on the surface of an object 7.
  • the channel 10' tapers, but this does not necessarily have to be the case. It is essential in this embodiment of the applicator 3 'that the catalyst 6' in the flow direction of
  • the catalyst 6 ' is designed as a network and allows in addition to a good contact to the passing sterilizing agent S and a uniform distribution of the exiting sterilant S. So the network ultimately supports the atomization of the sterilant S.

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

L'invention concerne un procédé pour stériliser la surface d'objets (7), en particulier en matériau d'emballage ou analogue. L'objectif de cette invention est d'augmenter l'efficacité d'agents stérilisants. A cet effet, dans une première étape, un agent stérilisant est amené à un dispositif d'application par un dispositif d'alimentation ; dans une deuxième étape, l'agent stérilisant (S) amené au dispositif d'application est mis en contact avec un catalyseur (6) puis activé et, dans une troisième étape, l'agent stérilisant (S) activé est appliqué sur la surface des objets à stériliser (7).
PCT/EP2006/060126 2005-03-01 2006-02-21 Procede et dispositif pour steriliser la surface d'objets Ceased WO2006092367A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510009875 DE102005009875B4 (de) 2005-03-01 2005-03-01 Verfahren und Vorrichtung zur Sterilisation der Oberfläche von Objekten
DE102005009875.4 2005-03-01

Publications (1)

Publication Number Publication Date
WO2006092367A1 true WO2006092367A1 (fr) 2006-09-08

Family

ID=36178099

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/060126 Ceased WO2006092367A1 (fr) 2005-03-01 2006-02-21 Procede et dispositif pour steriliser la surface d'objets

Country Status (3)

Country Link
DE (1) DE102005009875B4 (fr)
TW (1) TW200701997A (fr)
WO (1) WO2006092367A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010000436A1 (fr) * 2008-07-04 2010-01-07 Khs Ag Procédé et dispositif de traitement des conteneurs en matière plastique à usage unique

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102019127711A1 (de) * 2019-10-15 2021-04-15 Krones Ag Sterilisation von Behältern in Getränkeabfüllanlagen

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935371A (en) * 1986-12-31 1990-06-19 American Sterilizer Company Sterilizable gas permeable container for use in culturing living cells
US5622848A (en) * 1990-05-23 1997-04-22 Medical Discoveries, Inc. Electrically hydrolyzed salines as microbiocides for in vitro treatment of contaminated fluids containing blood
US6096266A (en) * 1998-07-10 2000-08-01 Box 03 International Method for disinfecting and sterilizing microbial contaminated materials
US6228324B1 (en) * 1997-11-28 2001-05-08 Seikagaku Corporation Sterilizing method for medical sterilization packaging and injection pack

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE401912B (sv) * 1976-10-07 1978-06-05 Tetra Pak Int Sett att sterilisera foremal medelst vetskeformigt steriliseringsmedel samt anordning for genomforande av settet
DE102004029803B4 (de) * 2004-06-19 2007-01-11 Khs Ag Gefäßbehandlungsmaschine zur Sterilisation von Behältern mittels H2O2

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935371A (en) * 1986-12-31 1990-06-19 American Sterilizer Company Sterilizable gas permeable container for use in culturing living cells
US5622848A (en) * 1990-05-23 1997-04-22 Medical Discoveries, Inc. Electrically hydrolyzed salines as microbiocides for in vitro treatment of contaminated fluids containing blood
US6228324B1 (en) * 1997-11-28 2001-05-08 Seikagaku Corporation Sterilizing method for medical sterilization packaging and injection pack
US6096266A (en) * 1998-07-10 2000-08-01 Box 03 International Method for disinfecting and sterilizing microbial contaminated materials

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010000436A1 (fr) * 2008-07-04 2010-01-07 Khs Ag Procédé et dispositif de traitement des conteneurs en matière plastique à usage unique

Also Published As

Publication number Publication date
DE102005009875B4 (de) 2008-01-17
DE102005009875A1 (de) 2006-09-07
TW200701997A (en) 2007-01-16

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