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WO2006073587A3 - Hemipteran 5-hydroxytryptamine 7 serotonin receptor - Google Patents

Hemipteran 5-hydroxytryptamine 7 serotonin receptor Download PDF

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Publication number
WO2006073587A3
WO2006073587A3 PCT/US2005/041892 US2005041892W WO2006073587A3 WO 2006073587 A3 WO2006073587 A3 WO 2006073587A3 US 2005041892 W US2005041892 W US 2005041892W WO 2006073587 A3 WO2006073587 A3 WO 2006073587A3
Authority
WO
WIPO (PCT)
Prior art keywords
serotonin receptor
disclosed
hemipteran
hydroxytryptamine
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/041892
Other languages
French (fr)
Other versions
WO2006073587A2 (en
Inventor
Debra A Yuhas
Jeffrey D Herron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FMC Corp
Original Assignee
FMC Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FMC Corp filed Critical FMC Corp
Publication of WO2006073587A2 publication Critical patent/WO2006073587A2/en
Anticipated expiration legal-status Critical
Publication of WO2006073587A3 publication Critical patent/WO2006073587A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G01N33/942—Serotonin, i.e. 5-hydroxy-tryptamine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Insects & Arthropods (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Novel nucleic acid sequences encoding the 5 HT-7 serotonin receptor, and recombinant expressions and host cells comprising the same are disclosed. Isolated the 5 HT-7 serotonin receptor, host cells expressing the 5 HT-7 serotonin receptor, methods of producing the 5 HT-7 serotonin receptor and antibodies specific for the 5 HT-7 serotonin receptor are also disclosed. Methods of identifying activators, inhibitors or of the 5 HT-7 serotonin receptor are disclosed.
PCT/US2005/041892 2004-11-23 2005-11-18 Hemipteran 5-hydroxytryptamine 7 serotonin receptor Ceased WO2006073587A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63051804P 2004-11-23 2004-11-23
US60/630,518 2004-11-23

Publications (2)

Publication Number Publication Date
WO2006073587A2 WO2006073587A2 (en) 2006-07-13
WO2006073587A3 true WO2006073587A3 (en) 2009-05-07

Family

ID=36647944

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/041892 Ceased WO2006073587A2 (en) 2004-11-23 2005-11-18 Hemipteran 5-hydroxytryptamine 7 serotonin receptor

Country Status (1)

Country Link
WO (1) WO2006073587A2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WITZ ET AL.: "Cloning and characterization of a drosophila serotonin receptor that activates adenylate cyclase.", PROC. NATL. ACAD. SCI. USA, vol. 87, November 1990 (1990-11-01), pages 8940 - 8944 *

Also Published As

Publication number Publication date
WO2006073587A2 (en) 2006-07-13

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