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WO2006068950A3 - Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers - Google Patents

Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers Download PDF

Info

Publication number
WO2006068950A3
WO2006068950A3 PCT/US2005/045646 US2005045646W WO2006068950A3 WO 2006068950 A3 WO2006068950 A3 WO 2006068950A3 US 2005045646 W US2005045646 W US 2005045646W WO 2006068950 A3 WO2006068950 A3 WO 2006068950A3
Authority
WO
WIPO (PCT)
Prior art keywords
siloxane
delivery device
drug delivery
containing copolymers
crosslinked polyurethane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/045646
Other languages
French (fr)
Other versions
WO2006068950A2 (en
Inventor
Yu-Chin Lai
Ruiwen Shi
William O Lever Jr
Dominic V Ruscio
Yan Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Publication of WO2006068950A2 publication Critical patent/WO2006068950A2/en
Publication of WO2006068950A3 publication Critical patent/WO2006068950A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes polyurethane-siloxane- containing copolymers crosslinked with hydrophilic monomers.
PCT/US2005/045646 2004-12-22 2005-12-19 Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers Ceased WO2006068950A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63848004P 2004-12-22 2004-12-22
US60/638,480 2004-12-22

Publications (2)

Publication Number Publication Date
WO2006068950A2 WO2006068950A2 (en) 2006-06-29
WO2006068950A3 true WO2006068950A3 (en) 2007-02-15

Family

ID=36602228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/045646 Ceased WO2006068950A2 (en) 2004-12-22 2005-12-19 Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers

Country Status (1)

Country Link
WO (1) WO2006068950A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053130A2 (en) * 2001-01-03 2002-07-11 Bausch & Lomb Incorporated Sustained release drug delivery devices with coated drug cores
WO2003040200A1 (en) * 2001-11-02 2003-05-15 Bausch & Lomb Incorporated High refractive index aromatic-based prepolymers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053130A2 (en) * 2001-01-03 2002-07-11 Bausch & Lomb Incorporated Sustained release drug delivery devices with coated drug cores
WO2003040200A1 (en) * 2001-11-02 2003-05-15 Bausch & Lomb Incorporated High refractive index aromatic-based prepolymers

Also Published As

Publication number Publication date
WO2006068950A2 (en) 2006-06-29

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