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WO2006067419A3 - Myrtaceous honey and the use thereof as immunomodulator - Google Patents

Myrtaceous honey and the use thereof as immunomodulator Download PDF

Info

Publication number
WO2006067419A3
WO2006067419A3 PCT/GB2005/004945 GB2005004945W WO2006067419A3 WO 2006067419 A3 WO2006067419 A3 WO 2006067419A3 GB 2005004945 W GB2005004945 W GB 2005004945W WO 2006067419 A3 WO2006067419 A3 WO 2006067419A3
Authority
WO
WIPO (PCT)
Prior art keywords
honey
myrtaceous
immunomodulator
casuarine
glycoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/004945
Other languages
French (fr)
Other versions
WO2006067419A2 (en
Inventor
Robert James Nash
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MNL Pharma Ltd
Original Assignee
MNL Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MNL Pharma Ltd filed Critical MNL Pharma Ltd
Publication of WO2006067419A2 publication Critical patent/WO2006067419A2/en
Publication of WO2006067419A3 publication Critical patent/WO2006067419A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A process for the production of a composition comprising a pyrrolizidine compound comprises the steps of: (a) providing myrtaceous honey; (b) extracting (e.g. isolating or purifying) casuarine and/or a glycoside thereof from the honey; and/or (c) chemically and/or enzymatically modifying the casuarine and/or glycoside thereof present in the honey.
PCT/GB2005/004945 2004-12-21 2005-12-20 Myrtaceous honey and the use thereof as immunomodulator Ceased WO2006067419A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427882.6A GB0427882D0 (en) 2004-12-21 2004-12-21 Therapeutic uses for honey
GB0427882.6 2004-12-21

Publications (2)

Publication Number Publication Date
WO2006067419A2 WO2006067419A2 (en) 2006-06-29
WO2006067419A3 true WO2006067419A3 (en) 2007-03-29

Family

ID=34090389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/004945 Ceased WO2006067419A2 (en) 2004-12-21 2005-12-20 Myrtaceous honey and the use thereof as immunomodulator

Country Status (2)

Country Link
GB (1) GB0427882D0 (en)
WO (1) WO2006067419A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008117019A1 (en) * 2007-03-24 2008-10-02 University College Cardiff Consultants Limited Tlr4 ligand isolated from honey

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004064715A2 (en) * 2003-01-23 2004-08-05 M N L Pharma Limited Polyhydroxylated pyrrolizidine
RU2236248C2 (en) * 2001-12-27 2004-09-20 Тулев Юрий Владимирович Immunotropic preparation "vitulin"

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2236248C2 (en) * 2001-12-27 2004-09-20 Тулев Юрий Владимирович Immunotropic preparation "vitulin"
WO2004064715A2 (en) * 2003-01-23 2004-08-05 M N L Pharma Limited Polyhydroxylated pyrrolizidine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200470, Derwent World Patents Index; Class B04, AN 2004-716838, XP002386166 *
EDGAR; J A; ROEDER; E; MOLYNEUX; R J: "Honey from plants containing pyrrolizidine alkaloids: A potential threat to health", J. AGRIC. FOOD CHEM., vol. 50, no. 10, 2002, pages 2719 -2730, XP002386235 *

Also Published As

Publication number Publication date
GB0427882D0 (en) 2005-01-19
WO2006067419A2 (en) 2006-06-29

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