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WO2006065788A3 - Novel muscarinic acetylcholine receptor antagonists - Google Patents

Novel muscarinic acetylcholine receptor antagonists Download PDF

Info

Publication number
WO2006065788A3
WO2006065788A3 PCT/US2005/045012 US2005045012W WO2006065788A3 WO 2006065788 A3 WO2006065788 A3 WO 2006065788A3 US 2005045012 W US2005045012 W US 2005045012W WO 2006065788 A3 WO2006065788 A3 WO 2006065788A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor antagonists
acetylcholine receptor
muscarinic acetylcholine
novel muscarinic
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/045012
Other languages
French (fr)
Other versions
WO2006065788A2 (en
Inventor
Jakob Busch-Petersen
Roderick S Davis
Wei Fu
Jian Jin
Dramane I Laine
Michael R Palovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of WO2006065788A2 publication Critical patent/WO2006065788A2/en
Publication of WO2006065788A3 publication Critical patent/WO2006065788A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
PCT/US2005/045012 2004-12-13 2005-12-13 Novel muscarinic acetylcholine receptor antagonists Ceased WO2006065788A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63570304P 2004-12-13 2004-12-13
US60/635,703 2004-12-13

Publications (2)

Publication Number Publication Date
WO2006065788A2 WO2006065788A2 (en) 2006-06-22
WO2006065788A3 true WO2006065788A3 (en) 2006-08-17

Family

ID=36588460

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/045012 Ceased WO2006065788A2 (en) 2004-12-13 2005-12-13 Novel muscarinic acetylcholine receptor antagonists

Country Status (1)

Country Link
WO (1) WO2006065788A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050250A1 (en) 2003-07-17 2005-04-08 Glaxo Group Ltd ANTAGONISTS OF ACETYLCHOLIN MUSCARINAL RECEPTORS
EP1677795B1 (en) 2003-10-14 2011-01-05 Glaxo Group Limited Muscarinic acetycholine receptor antagonists
CA2542636A1 (en) 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
TW200524577A (en) 2003-11-04 2005-08-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
JP2007529513A (en) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド M3 muscarinic acetylcholine receptor antagonist
TWI363759B (en) 2004-04-27 2012-05-11 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
JP2007537261A (en) 2004-05-13 2007-12-20 グラクソ　グループ　リミテッド Muscarinic acetylcholine receptor antagonist
WO2006055553A2 (en) 2004-11-15 2006-05-26 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
WO2006065755A2 (en) * 2004-12-13 2006-06-22 Glaxo Group Limited Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
US7767691B2 (en) 2005-08-18 2010-08-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists containing an azoniabiocyclo[2.2.1] heptane ring system
CN101730699A (en) 2007-03-21 2010-06-09 百时美施贵宝公司 Can be used for treating the condensed heterocyclic compouds of proliferative, allergy, autoimmunity and diseases associated with inflammation
TW200946526A (en) 2008-02-06 2009-11-16 Glaxo Group Ltd Dual pharmacophores-PDE4-muscarinic antagonistics
CL2009000250A1 (en) 2008-02-06 2009-09-11 Glaxo Group Ltd Compounds derived from pyrazolo [3,4-b] pyridine carboxamide; pharmaceutical composition comprising them; and its use in the treatment of asthma, copd and rhinitis.
AR070563A1 (en) 2008-02-06 2010-04-21 Glaxo Group Ltd COMPOSITE OF A CONDENSED BICYCLE PIRAZOL-PIRIDIN-AMINA, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A USEFUL MEDICATION FOR THE TREATMENT OF RESPIRATORY DISEASES.
US8476430B2 (en) 2008-07-24 2013-07-02 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
GB0918924D0 (en) * 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
TW201414737A (en) 2012-07-13 2014-04-16 必治妥美雅史谷比公司 Imidazotriazinecarbonitriles useful as kinase inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6657064B2 (en) * 1999-10-08 2003-12-02 Gruenenthal Gmbh Bicyclic imidazo-5-yl-amine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6657064B2 (en) * 1999-10-08 2003-12-02 Gruenenthal Gmbh Bicyclic imidazo-5-yl-amine derivatives

Also Published As

Publication number Publication date
WO2006065788A2 (en) 2006-06-22

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