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WO2006054280A3 - System and method for delivering fluid into flexible biological barrier - Google Patents

System and method for delivering fluid into flexible biological barrier Download PDF

Info

Publication number
WO2006054280A3
WO2006054280A3 PCT/IL2005/000522 IL2005000522W WO2006054280A3 WO 2006054280 A3 WO2006054280 A3 WO 2006054280A3 IL 2005000522 W IL2005000522 W IL 2005000522W WO 2006054280 A3 WO2006054280 A3 WO 2006054280A3
Authority
WO
WIPO (PCT)
Prior art keywords
barrier
biological barrier
biological
delivering fluid
flexible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2005/000522
Other languages
French (fr)
Other versions
WO2006054280A2 (en
Inventor
Yehushua Yeshurun
Meir Hefetz
Yoel Sefi
Yotam Levin
Gilad Lavi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NanoPass Tech Ltd
Original Assignee
NanoPass Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2004/001065 external-priority patent/WO2005049107A2/en
Application filed by NanoPass Tech Ltd filed Critical NanoPass Tech Ltd
Priority to US11/719,541 priority Critical patent/US8007466B2/en
Priority to EP05741986.3A priority patent/EP1819379B1/en
Priority to JP2007542497A priority patent/JP5026980B2/en
Priority to CA2587216A priority patent/CA2587216C/en
Publication of WO2006054280A2 publication Critical patent/WO2006054280A2/en
Publication of WO2006054280A3 publication Critical patent/WO2006054280A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/341—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub angularly adjustable or angled away from the axis of the injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A system and method for delivering fluid into a flexible biological barrier employs a microneedle (12) structure wherein a final position of microneedles inserted into the biological barrier (14) is generally sideways projecting from the delivery configuration instead of the conventional downwards projecting arrangement. The microneedles project from a relief surface (16) which is distinct from a primary biological-barrier contact region (18, 26) of the delivery configuration, and is typically angled upwards away from the biological barrier. During insertion, the contact region is brought into contact with the biological barrier and moved parallel to the surface of the flexible biological barrier so as to generate a boundary (20) between a stretched portion (22) and a non-stretched portion (24) of the barrier.
PCT/IL2005/000522 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier Ceased WO2006054280A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US11/719,541 US8007466B2 (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier
EP05741986.3A EP1819379B1 (en) 2004-11-18 2005-05-19 System for delivering fluid into flexible biological barrier
JP2007542497A JP5026980B2 (en) 2004-11-18 2005-05-19 Device for supplying fluid into a flexible biological barrier
CA2587216A CA2587216C (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/IL2004/001065 WO2005049107A2 (en) 2003-11-18 2004-11-18 Enhanced penetration system and method for sliding microneedles
ILPCT/IL2004/001065 2004-11-18
US65186105P 2005-02-11 2005-02-11
US60/651,861 2005-02-11

Publications (2)

Publication Number Publication Date
WO2006054280A2 WO2006054280A2 (en) 2006-05-26
WO2006054280A3 true WO2006054280A3 (en) 2006-10-12

Family

ID=36407535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000522 Ceased WO2006054280A2 (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier

Country Status (4)

Country Link
US (1) US8007466B2 (en)
EP (1) EP1819379B1 (en)
CA (1) CA2587216C (en)
WO (1) WO2006054280A2 (en)

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EP2563451B1 (en) 2010-04-28 2017-11-01 Kimberly-Clark Worldwide, Inc. MEDICAL DEVICES FOR DELIVERY OF siRNA
GB2487899A (en) 2011-02-01 2012-08-15 Olberon Ltd Needle holder with grip means
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
US8710200B2 (en) 2011-03-31 2014-04-29 Moderna Therapeutics, Inc. Engineered nucleic acids encoding a modified erythropoietin and their expression
GB201112933D0 (en) 2011-07-27 2011-09-14 Olberon Ltd Improvements relating to needle insertion or cannulation
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
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CA2933552A1 (en) 2013-12-23 2015-07-02 Alk-Abello A/S Peptide combinations and uses thereof in treating dust mite allergy
WO2015131053A1 (en) 2014-02-28 2015-09-03 Alk-Abelló A/S Polypeptides derived from phl p and methods and uses thereof for immune response modulation
JP5896093B1 (en) * 2014-04-14 2016-03-30 凸版印刷株式会社 Injection device
WO2016209959A2 (en) 2015-06-22 2016-12-29 Alk-Abelló A/S Peptide combinations and use thereof in treating cedar pollen allergy
US11013781B2 (en) 2015-07-01 2021-05-25 Alk-Abelló As Peptide combinations and uses thereof for treating grass allergy
WO2017179025A1 (en) 2016-04-15 2017-10-19 Alk-Abelló A/S Epitope polypeptides of ragweed pollen allergens
US20180185623A1 (en) * 2017-01-03 2018-07-05 Nanopass Technologies Ltd. Clamp for use in assembly of a microprotrusion device and corresponding method
US12377219B2 (en) 2021-03-01 2025-08-05 Deka Products Limited Partnership Medical agent dispensing apparatuses, systems, and methods
US12161832B2 (en) 2021-03-01 2024-12-10 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US12357804B2 (en) 2021-03-01 2025-07-15 Deka Products Limited Partnership Medical agent dispensing systems, methods, and apparatuses
US11717660B2 (en) 2021-07-29 2023-08-08 Nanopass Technologies Ltd. Silicon microneedle structure and production method

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Also Published As

Publication number Publication date
US8007466B2 (en) 2011-08-30
WO2006054280A2 (en) 2006-05-26
EP1819379A2 (en) 2007-08-22
CA2587216A1 (en) 2006-05-26
EP1819379B1 (en) 2016-08-31
US20090069788A1 (en) 2009-03-12
EP1819379A4 (en) 2010-10-06
CA2587216C (en) 2014-11-18

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