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WO2006051333A3 - Leucine-rich repeat (lrr) motif containing proteins - Google Patents

Leucine-rich repeat (lrr) motif containing proteins Download PDF

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Publication number
WO2006051333A3
WO2006051333A3 PCT/GB2005/004390 GB2005004390W WO2006051333A3 WO 2006051333 A3 WO2006051333 A3 WO 2006051333A3 GB 2005004390 W GB2005004390 W GB 2005004390W WO 2006051333 A3 WO2006051333 A3 WO 2006051333A3
Authority
WO
WIPO (PCT)
Prior art keywords
lrr
leucine
rich repeat
containing proteins
motif containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/004390
Other languages
French (fr)
Other versions
WO2006051333A2 (en
Inventor
David Michalovich
Simon John White
Melanie Yorke
Kinsey Maundrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ares Trading SA
Original Assignee
Ares Trading SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading SA filed Critical Ares Trading SA
Priority to JP2007540722A priority Critical patent/JP2008519593A/en
Priority to CA002586486A priority patent/CA2586486A1/en
Priority to AU2005303536A priority patent/AU2005303536A1/en
Priority to EP05803576A priority patent/EP1814903A2/en
Publication of WO2006051333A2 publication Critical patent/WO2006051333A2/en
Publication of WO2006051333A3 publication Critical patent/WO2006051333A3/en
Priority to IL182960A priority patent/IL182960A0/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

There are provided proteins, termed INSP168, INSP168-SV1, INSP149 and INSP169, herein identified as leucine-rich repeat (LRR) motif containing proteins, and the use of these proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
PCT/GB2005/004390 2004-11-15 2005-11-15 Leucine-rich repeat (lrr) motif containing proteins Ceased WO2006051333A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2007540722A JP2008519593A (en) 2004-11-15 2005-11-15 Leucine rich repeat (LRR) motif-containing protein
CA002586486A CA2586486A1 (en) 2004-11-15 2005-11-15 Leucine-rich repeat (lrr) motif containing proteins
AU2005303536A AU2005303536A1 (en) 2004-11-15 2005-11-15 Leucine-rich repeat (LRR) motif containing proteins
EP05803576A EP1814903A2 (en) 2004-11-15 2005-11-15 Leucine-rich repeat (lrr) motif containing proteins
IL182960A IL182960A0 (en) 2004-11-15 2007-05-03 Leucine-rich repeat (lrr) motif containing proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0425197.1 2004-11-15
GB0425197A GB0425197D0 (en) 2004-11-15 2004-11-15 Leucine-rich repeat (LRR) motif containing proteins

Publications (2)

Publication Number Publication Date
WO2006051333A2 WO2006051333A2 (en) 2006-05-18
WO2006051333A3 true WO2006051333A3 (en) 2006-07-20

Family

ID=33523767

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/004390 Ceased WO2006051333A2 (en) 2004-11-15 2005-11-15 Leucine-rich repeat (lrr) motif containing proteins

Country Status (7)

Country Link
EP (1) EP1814903A2 (en)
JP (1) JP2008519593A (en)
AU (1) AU2005303536A1 (en)
CA (1) CA2586486A1 (en)
GB (1) GB0425197D0 (en)
IL (1) IL182960A0 (en)
WO (1) WO2006051333A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116036239B (en) * 2023-03-28 2023-06-23 中国人民解放军军事科学院军事医学研究院 Application of NEP1-40 in preparation of medicine for specifically inhibiting illusion effect
WO2025096678A1 (en) * 2023-10-30 2025-05-08 The Board Of Regents Of The University Of Texas System Novel cell projection targeting signal peptides and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001128686A (en) * 1999-11-09 2001-05-15 Tanabe Seiyaku Co Ltd Novel proteins and their genes
WO2003054166A2 (en) * 2001-12-20 2003-07-03 Incyte Genomics, Inc. Nucleotide polymorphisms associated with osteoarthritis
EP1447413A2 (en) * 2003-02-14 2004-08-18 Research Association for Biotechnology Full-length human cDNA

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001128686A (en) * 1999-11-09 2001-05-15 Tanabe Seiyaku Co Ltd Novel proteins and their genes
WO2003054166A2 (en) * 2001-12-20 2003-07-03 Incyte Genomics, Inc. Nucleotide polymorphisms associated with osteoarthritis
EP1447413A2 (en) * 2003-02-14 2004-08-18 Research Association for Biotechnology Full-length human cDNA

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 19 May 2005 (2005-05-19), "TC102061 Human adult whole brain, large insert, pCMV expression library Homo sapiens cDNA clone TC102061 5' similar to Homo sapiens similar to retina specific protein PAL (LOC132703), mRNA sequence.", XP002378210, retrieved from EBI accession no. EM_PRO:DN994055 Database accession no. DN994055 *
DATABASE EMBL [online] 9 September 2003 (2003-09-09), "Homo sapiens cDNA FLJ44691 fis, clone BRACE3013874.", XP002378211, retrieved from EBI accession no. EM_PRO:AK126648 Database accession no. AK126648 *
GOMI F ET AL: "Molecular cloning of a novel membrane glycoprotein, Pal, specifically expressed in photoreceptor cells of the retina and containing leucine-rich repeat", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 20, no. 9, 1 May 2000 (2000-05-01), pages 3206 - 3213, XP002229022, ISSN: 0270-6474 *
MUNFUS DELICIA L ET AL: "Identification of novel transmembrane molecules with leucine rich repeat, immunoglobulin and fibronectin domains.", FASEB JOURNAL, vol. 17, no. 4-5, March 2003 (2003-03-01), & FASEB MEETING ON EXPERIMENTAL BIOLOGY: TRANSLATING THE GENOME; SAN DIEGO, CA, USA; APRIL 11-15, 2003, pages Abstract No. 366.7 URL - http://ww, XP002378187, ISSN: 0892-6638 *
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 22 9 March 2001 (2001-03-09) *

Also Published As

Publication number Publication date
IL182960A0 (en) 2007-08-19
WO2006051333A2 (en) 2006-05-18
EP1814903A2 (en) 2007-08-08
CA2586486A1 (en) 2006-05-18
JP2008519593A (en) 2008-06-12
AU2005303536A1 (en) 2006-05-18
GB0425197D0 (en) 2004-12-15

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