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WO2006045314A3 - Use of a growth hormone secretatogue for increasing or maintaining lean body mass and/or for treatment of chronic obstructive pulmonary disease - Google Patents

Use of a growth hormone secretatogue for increasing or maintaining lean body mass and/or for treatment of chronic obstructive pulmonary disease Download PDF

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Publication number
WO2006045314A3
WO2006045314A3 PCT/DK2005/000689 DK2005000689W WO2006045314A3 WO 2006045314 A3 WO2006045314 A3 WO 2006045314A3 DK 2005000689 W DK2005000689 W DK 2005000689W WO 2006045314 A3 WO2006045314 A3 WO 2006045314A3
Authority
WO
WIPO (PCT)
Prior art keywords
increasing
body mass
lean body
treatment
growth hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2005/000689
Other languages
French (fr)
Other versions
WO2006045314A2 (en
Inventor
Birgitte Holst Lange
Hans T Schambye
Tina Geritz Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gastrotech Pharma AS
Original Assignee
Gastrotech Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gastrotech Pharma AS filed Critical Gastrotech Pharma AS
Publication of WO2006045314A2 publication Critical patent/WO2006045314A2/en
Publication of WO2006045314A3 publication Critical patent/WO2006045314A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to a method for increasing or maintaining lean body mass in an individual in need thereof, by administering a secretagogue. The present invention also relates in another aspect to the use of a secretagogue for the production of a medicament for use in increasing or maintaining an individual's lean body mass, preferably in an individual suffering from, or at risk of suffering from, cachexia, such as cancer cachexia.
PCT/DK2005/000689 2004-10-27 2005-10-26 Use of a growth hormone secretatogue for increasing or maintaining lean body mass and/or for treatment of chronic obstructive pulmonary disease Ceased WO2006045314A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DKPA200401657 2004-10-27
DKPA200401657 2004-10-27
US65311605P 2005-02-16 2005-02-16
DKPA200500242 2005-02-16
US60/653,116 2005-02-16
DKPA200500242 2005-02-16

Publications (2)

Publication Number Publication Date
WO2006045314A2 WO2006045314A2 (en) 2006-05-04
WO2006045314A3 true WO2006045314A3 (en) 2007-04-12

Family

ID=36228137

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2005/000689 Ceased WO2006045314A2 (en) 2004-10-27 2005-10-26 Use of a growth hormone secretatogue for increasing or maintaining lean body mass and/or for treatment of chronic obstructive pulmonary disease

Country Status (1)

Country Link
WO (1) WO2006045314A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7851448B2 (en) 2004-11-24 2010-12-14 Neopro Labs, Llc Methods for modulating activities in plants
US8217141B2 (en) 2007-05-17 2012-07-10 Neopro Labs, Llc Crystalline and amorphous forms of peptide

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331922B (en) 2002-08-09 2010-10-21 Ipsen Pharma Sas Growth hormone releasing peptides
CA2647835A1 (en) 2006-03-28 2007-10-04 Neopro Labs, Llc Methods and compositions for treating conditions
CN101657436A (en) 2007-02-09 2010-02-24 特兰齐姆制药公司 macrocyclic ghrelin receptor modulators and methods of use thereof
TW200916113A (en) 2007-08-08 2009-04-16 Sod Conseils Rech Applic Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
KR20100056507A (en) * 2007-09-11 2010-05-27 몬도바이오테크 래보래토리즈 아게 Use of the peptide pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys as a therapeutic agent
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2016144978A1 (en) * 2015-03-09 2016-09-15 Oxeia Biopharmaceuticals, Inc. Methods of treating cognitive impairments or dysfunction
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1002802A1 (en) * 1998-11-20 2000-05-24 Pfizer Products Inc. Dipeptide derivatives as growth hormone secretagogues
WO2001092292A2 (en) * 2000-05-30 2001-12-06 Merck & Co., Inc. Ghrelin analogs
WO2004014415A1 (en) * 2002-08-09 2004-02-19 Societe De Conseil De Recherches Et D'applications Scientifiques, S.A.S. Growth hormone releasing peptides
WO2005014032A2 (en) * 2003-08-06 2005-02-17 Gastrotech Pharma A/S Use of secretagogues like ghrelin in cancer cachexia and for stimulating appetite
WO2005097174A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Uses of a combination of ghrelin and somatotropin for the treatment of cachexia
WO2005097831A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Uses of isolated binding members capable of binding specifically to secretagogues
WO2005097173A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Use of ghrelin for the treatment of hyperthyroidism

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1002802A1 (en) * 1998-11-20 2000-05-24 Pfizer Products Inc. Dipeptide derivatives as growth hormone secretagogues
WO2001092292A2 (en) * 2000-05-30 2001-12-06 Merck & Co., Inc. Ghrelin analogs
WO2004014415A1 (en) * 2002-08-09 2004-02-19 Societe De Conseil De Recherches Et D'applications Scientifiques, S.A.S. Growth hormone releasing peptides
WO2005014032A2 (en) * 2003-08-06 2005-02-17 Gastrotech Pharma A/S Use of secretagogues like ghrelin in cancer cachexia and for stimulating appetite
WO2005097174A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Uses of a combination of ghrelin and somatotropin for the treatment of cachexia
WO2005097831A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Uses of isolated binding members capable of binding specifically to secretagogues
WO2005097173A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Use of ghrelin for the treatment of hyperthyroidism

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CARPINO PHILIP A: "Recent developments in ghrelin receptor (GHS-R1a) agonists and antagonists", EXPERT OPINION ON THERAPEUTIC PATENTS, ASHLEY PUBLICATIONS, GB, vol. 12, no. 11, 2002, pages 1599 - 1618, XP002313948, ISSN: 1354-3776 *
DIXIT V D ET AL: "GHRELIN INHIBITS LEPTIN- AND ACTIVATION-INDUCED PROINFLAMMATORY CYTOKINE EXPRESSION BY HUMAN MONOCYTES AND T CELLS", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 114, no. 1, July 2004 (2004-07-01), pages 57 - 66, XP001207514, ISSN: 0021-9738 *
TOSHINAI K ET AL: "Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 281, no. 5, 16 March 2001 (2001-03-16), pages 1220 - 1225, XP002243977, ISSN: 0006-291X *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7851448B2 (en) 2004-11-24 2010-12-14 Neopro Labs, Llc Methods for modulating activities in plants
US7858586B2 (en) 2004-11-24 2010-12-28 Neopro Labs, Llc Method of treating condition in animal
US8492159B2 (en) 2004-11-24 2013-07-23 Neopro Pain, Inc. Methods and compositions for treating conditions
US8530432B2 (en) 2004-11-24 2013-09-10 Neopro Labs, Llc Methods and compositions for treating conditions
US8217141B2 (en) 2007-05-17 2012-07-10 Neopro Labs, Llc Crystalline and amorphous forms of peptide

Also Published As

Publication number Publication date
WO2006045314A2 (en) 2006-05-04

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