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WO2005121321A3 - Compositions comprising female germline stem cells and methods of use thereof - Google Patents

Compositions comprising female germline stem cells and methods of use thereof Download PDF

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Publication number
WO2005121321A3
WO2005121321A3 PCT/US2005/017221 US2005017221W WO2005121321A3 WO 2005121321 A3 WO2005121321 A3 WO 2005121321A3 US 2005017221 W US2005017221 W US 2005017221W WO 2005121321 A3 WO2005121321 A3 WO 2005121321A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
stem cells
compositions
germline stem
female germline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/017221
Other languages
French (fr)
Other versions
WO2005121321A2 (en
Inventor
Jonathan L Tilly
Joshua Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Priority to CA2566851A priority Critical patent/CA2566851C/en
Priority to SI200532007T priority patent/SI1765085T1/en
Priority to EP05782697.6A priority patent/EP1765085B1/en
Priority to EP15168666.4A priority patent/EP2987855B1/en
Priority to PL05782697T priority patent/PL1765085T3/en
Priority to DK05782697.6T priority patent/DK1765085T3/en
Priority to JP2007527367A priority patent/JP2007537754A/en
Priority to AU2005252636A priority patent/AU2005252636A1/en
Priority to EP18207405.4A priority patent/EP3498827A1/en
Priority to ES05782697.6T priority patent/ES2547953T3/en
Publication of WO2005121321A2 publication Critical patent/WO2005121321A2/en
Publication of WO2005121321A3 publication Critical patent/WO2005121321A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/43—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to female germline stem cells and their progenitors, methods of isolation thereof, and methods of use thereof.
PCT/US2005/017221 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof Ceased WO2005121321A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CA2566851A CA2566851C (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
SI200532007T SI1765085T1 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
EP05782697.6A EP1765085B1 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
EP15168666.4A EP2987855B1 (en) 2004-05-17 2005-05-17 Isolation of female germline stem cells
PL05782697T PL1765085T3 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
DK05782697.6T DK1765085T3 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
JP2007527367A JP2007537754A (en) 2004-05-17 2005-05-17 Methods and compositions for producing germ cells from female germline stem cells
AU2005252636A AU2005252636A1 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
EP18207405.4A EP3498827A1 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
ES05782697.6T ES2547953T3 (en) 2004-05-17 2005-05-17 Compositions comprising female germ stem cells and methods of use thereof

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US57222204P 2004-05-17 2004-05-17
US60/572,222 2004-05-17
US57418704P 2004-05-24 2004-05-24
US60/574,187 2004-05-24
US58664104P 2004-07-09 2004-07-09
US60/586,641 2004-07-09

Publications (2)

Publication Number Publication Date
WO2005121321A2 WO2005121321A2 (en) 2005-12-22
WO2005121321A3 true WO2005121321A3 (en) 2006-09-28

Family

ID=35428927

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2005/017233 Ceased WO2005113752A2 (en) 2004-05-17 2005-05-17 Methods and compositions for producing germ cells from peripheral blood derived germline stem cells
PCT/US2005/017221 Ceased WO2005121321A2 (en) 2004-05-17 2005-05-17 Compositions comprising female germline stem cells and methods of use thereof
PCT/US2005/017234 Ceased WO2006001938A2 (en) 2004-05-17 2005-05-17 Methods and compositions for producing germ cells from bone marrow derived germline stem cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2005/017233 Ceased WO2005113752A2 (en) 2004-05-17 2005-05-17 Methods and compositions for producing germ cells from peripheral blood derived germline stem cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2005/017234 Ceased WO2006001938A2 (en) 2004-05-17 2005-05-17 Methods and compositions for producing germ cells from bone marrow derived germline stem cells

Country Status (13)

Country Link
US (7) US20060015961A1 (en)
EP (5) EP1765985A4 (en)
JP (3) JP2007537754A (en)
AU (3) AU2005252636A1 (en)
CA (6) CA2566857A1 (en)
CY (1) CY1116768T1 (en)
DK (1) DK1765085T3 (en)
ES (1) ES2547953T3 (en)
HU (1) HUE027620T2 (en)
PL (1) PL1765085T3 (en)
PT (1) PT1765085E (en)
SI (1) SI1765085T1 (en)
WO (3) WO2005113752A2 (en)

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US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
CA2566857A1 (en) 2004-05-17 2005-12-01 The General Hospital Corporation Methods and compositions for producing germ cells from peripheral blood derived germline stem cells
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WO2009042127A2 (en) * 2007-09-24 2009-04-02 The General Hospital Corporation Compositions and methods for rescuing fertility
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JP7021828B2 (en) * 2017-11-10 2022-02-17 一公 川島 How to induce meiosis of ovarian-derived stem cells
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