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WO2005113761A3 - Enzymes alanine transaminase et procedes d'utilisation - Google Patents

Enzymes alanine transaminase et procedes d'utilisation Download PDF

Info

Publication number
WO2005113761A3
WO2005113761A3 PCT/US2005/013019 US2005013019W WO2005113761A3 WO 2005113761 A3 WO2005113761 A3 WO 2005113761A3 US 2005013019 W US2005013019 W US 2005013019W WO 2005113761 A3 WO2005113761 A3 WO 2005113761A3
Authority
WO
WIPO (PCT)
Prior art keywords
alt
polypeptides
alanine transaminase
methods
transaminase enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/013019
Other languages
English (en)
Other versions
WO2005113761A2 (fr
Inventor
Da-Wei Gong
Alan R Shuldiner
Rong-Ze Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland Baltimore
University of Maryland College Park
Original Assignee
University of Maryland Baltimore
University of Maryland College Park
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland Baltimore, University of Maryland College Park filed Critical University of Maryland Baltimore
Priority to US11/587,331 priority Critical patent/US7914985B2/en
Publication of WO2005113761A2 publication Critical patent/WO2005113761A2/fr
Anticipated expiration legal-status Critical
Publication of WO2005113761A3 publication Critical patent/WO2005113761A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polypeptides alanine transaminase (ALT) et leur utilisation comme marqueurs de diagnostic pour prévenir et contrôler les dégâts tissulaires et/ou les défaillances tissulaires. Ces polypeptides sont de type murin, souris et/ou rat, et ils permettent de déceler, prévoir et/ou déterminer les processus hépatiques d'un animal, en particulier la souris et/ou le rat.
PCT/US2005/013019 2004-04-19 2005-04-19 Enzymes alanine transaminase et procedes d'utilisation Ceased WO2005113761A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/587,331 US7914985B2 (en) 2005-04-19 2005-04-19 Alanine transaminase enzymes and methods of use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56338904P 2004-04-19 2004-04-19
US60/563,389 2004-04-19
US58812604P 2004-07-15 2004-07-15
US60/588,126 2004-07-15

Publications (2)

Publication Number Publication Date
WO2005113761A2 WO2005113761A2 (fr) 2005-12-01
WO2005113761A3 true WO2005113761A3 (fr) 2007-05-24

Family

ID=35428929

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/013019 Ceased WO2005113761A2 (fr) 2004-04-19 2005-04-19 Enzymes alanine transaminase et procedes d'utilisation

Country Status (1)

Country Link
WO (1) WO2005113761A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007136822A2 (fr) * 2006-05-19 2007-11-29 George Mason Intellectual Properties, Inc. Diagnostic de maladie du foie utilisant l'état d'activation de la voie akt/mtor/irs dans les adipocytes
ME03529B (fr) 2008-01-11 2020-04-20 Reata Pharmaceuticals Inc Triterpénoïdes synthétiques et procédés d'utilisation dans le traitement de maladies
WO2009133169A1 (fr) 2008-05-02 2009-11-05 General Electric Company Procédé de détermination de l’activité de la transaminase alanine (alt) par détection <sp>13</sp>c-mr au moyen de <sp>13</sp>c-pyruvate hyperpolarisé
EP2558105B1 (fr) 2010-04-12 2019-11-20 Reata Pharmaceuticals, Inc. Bardoxolone methyl pour le traitement de l'obésité
CN107884572A (zh) * 2016-09-30 2018-04-06 南京澳百生物技术有限公司 护理点测定法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0568548A (ja) * 1991-08-06 1993-03-23 Chemo Sero Therapeut Res Inst ヒトａｌｔをコードする遺伝子断片
WO2002092768A2 (fr) * 2001-05-14 2002-11-21 University Of Maryland, Baltimore Nouvelle enzyme transaminase alanine et procedes d'utilisation de celle-ci

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0568548A (ja) * 1991-08-06 1993-03-23 Chemo Sero Therapeut Res Inst ヒトａｌｔをコードする遺伝子断片
WO2002092768A2 (fr) * 2001-05-14 2002-11-21 University Of Maryland, Baltimore Nouvelle enzyme transaminase alanine et procedes d'utilisation de celle-ci

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISSPROT [online] 1 May 1992 (1992-05-01), XP003015521, Database accession no. (P25409) *

Also Published As

Publication number Publication date
WO2005113761A2 (fr) 2005-12-01

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