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WO2005113419A3 - Systemes, dispositifs et procedes de relargage electrocinetique de medicament - Google Patents

Systemes, dispositifs et procedes de relargage electrocinetique de medicament Download PDF

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Publication number
WO2005113419A3
WO2005113419A3 PCT/US2005/013728 US2005013728W WO2005113419A3 WO 2005113419 A3 WO2005113419 A3 WO 2005113419A3 US 2005013728 W US2005013728 W US 2005013728W WO 2005113419 A3 WO2005113419 A3 WO 2005113419A3
Authority
WO
WIPO (PCT)
Prior art keywords
reservoir
fluid
fluid reservoir
devices
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/013728
Other languages
English (en)
Other versions
WO2005113419A2 (fr
Inventor
Deon S Anex
Phillip H Paul
David W Neyer
Edwin K Hlavka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eksigent Technologies LLC
Original Assignee
Eksigent Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eksigent Technologies LLC filed Critical Eksigent Technologies LLC
Priority to AU2005245347A priority Critical patent/AU2005245347A1/en
Priority to EP05779953.8A priority patent/EP1740497A4/fr
Priority to CN2005800186796A priority patent/CN101365885B/zh
Priority to JP2007509658A priority patent/JP4646976B2/ja
Priority to CA2564800A priority patent/CA2564800C/fr
Publication of WO2005113419A2 publication Critical patent/WO2005113419A2/fr
Anticipated expiration legal-status Critical
Publication of WO2005113419A3 publication Critical patent/WO2005113419A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
    • A61M5/1483—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags using flexible bags externally pressurised by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dermatology (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Micromachines (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Les dispositifs, systèmes et procédés de l'invention utilisent des pompes électrocinétiques capables de générer un flux à pressions hautes et basses pour diverses applications médicales, dont le relargage de médicament et l'échantillonnage d'analyte. Les pompes EC et les systèmes de l'invention sont configurés et construits de manière qu'ils soient de fabrication économique, compacts et précis.
PCT/US2005/013728 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament Ceased WO2005113419A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2005245347A AU2005245347A1 (en) 2004-04-21 2005-04-21 Electrokinetic delivery systems, devices and methods
EP05779953.8A EP1740497A4 (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament
CN2005800186796A CN101365885B (zh) 2004-04-21 2005-04-21 电动输送系统、装置和方法
JP2007509658A JP4646976B2 (ja) 2004-04-21 2005-04-21 界面動電送達システム、装置及び方法
CA2564800A CA2564800C (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56449704P 2004-04-21 2004-04-21
US60/564,497 2004-04-21

Publications (2)

Publication Number Publication Date
WO2005113419A2 WO2005113419A2 (fr) 2005-12-01
WO2005113419A3 true WO2005113419A3 (fr) 2007-12-27

Family

ID=35428903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/013728 Ceased WO2005113419A2 (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament

Country Status (6)

Country Link
EP (1) EP1740497A4 (fr)
JP (1) JP4646976B2 (fr)
CN (1) CN101365885B (fr)
AU (1) AU2005245347A1 (fr)
CA (1) CA2564800C (fr)
WO (1) WO2005113419A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9416777B2 (en) 2014-09-26 2016-08-16 Becton, Dickinson And Company Control circuits for electrochemical pump with E-valves

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2833354C (fr) * 2006-03-14 2015-12-15 University Of Southern California Dispositif mems et procede de livraison d'agents therapeutiques
EP2015805A1 (fr) * 2006-04-28 2009-01-21 Koninklijke Philips Electronics N.V. Pompe osmotique comprenant au moins un matériau à charger
US8694077B2 (en) 2006-10-06 2014-04-08 The Cleveland Clinic Foundation Apparatus and method for targeting a body tissue
WO2008070262A2 (fr) 2006-10-06 2008-06-12 The Cleveland Clinic Foundation Appareil et procédé pour cibler un tissu cellulaire
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
EP2712407A4 (fr) * 2011-05-05 2015-06-03 Eksigent Technologies Llc Système et procédé de commande de pression différentielle d'une pompe électrocinétique à mouvement alternatif
US8979511B2 (en) * 2011-05-05 2015-03-17 Eksigent Technologies, Llc Gel coupling diaphragm for electrokinetic delivery systems
WO2014006197A1 (fr) * 2012-07-06 2014-01-09 Sanofi-Aventis Deutschland Gmbh Dispositif d'administration de médicament
EP2908743B1 (fr) 2012-10-22 2018-08-22 The Cleveland Clinic Foundation Appareil de ciblage d'un tissu corporel
WO2014125518A1 (fr) * 2013-02-18 2014-08-21 テルモ株式会社 Dispositif ainsi que système d'administration de médicament, et procédé de commande de ceux-ci
CN106714871A (zh) * 2014-06-25 2017-05-24 魏民 用于给药的输液装置
EP3240591A4 (fr) * 2014-12-30 2018-09-05 MiniPumps, LLC Pompes à membrane électrolytique implantables
KR101910932B1 (ko) * 2016-08-31 2018-10-23 이오플로우(주) 전기 삼투 펌프
KR101928297B1 (ko) 2016-09-08 2018-12-12 이오플로우(주) 약액 주입장치
US20210330751A1 (en) * 2016-11-09 2021-10-28 PhysioLogic Devices, Inc. Insulins Compatible with New Generation Implantable Pumps
EP3338832A1 (fr) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Dispositif d'administration de médicaments
WO2018194041A1 (fr) * 2017-04-21 2018-10-25 ヨダカ技研株式会社 Dispositif de perfusion compact portatif
GB201714645D0 (en) 2017-09-12 2017-10-25 Osmotex Ag Method
US10809139B2 (en) * 2018-02-14 2020-10-20 Carefusion 303, Inc. Integrated sensor to monitor fluid delivery
JP6744527B1 (ja) * 2020-04-01 2020-08-19 アットドウス株式会社 薬液投与ユニット、薬液投与モジュール、薬液投与装置、及び投薬管理システム
TWI806182B (zh) * 2020-11-18 2023-06-21 潔霺生醫科技股份有限公司 多段式氣體致動供藥裝置及方法

Citations (7)

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Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4140122A (en) * 1976-06-11 1979-02-20 Siemens Aktiengesellschaft Implantable dosing device
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
US6409698B1 (en) * 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US20030232203A1 (en) * 2002-01-18 2003-12-18 The Regents Of The University Of Michigan Porous polymers: compositions and uses thereof
US6719535B2 (en) * 2002-01-31 2004-04-13 Eksigent Technologies, Llc Variable potential electrokinetic device

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JP2530220B2 (ja) * 1989-03-03 1996-09-04 日本特殊陶業株式会社 液体混合物分離装置
US5351164A (en) * 1991-10-29 1994-09-27 T.N. Frantsevich Institute For Problems In Materials Science Electrolytic double layer capacitor
ATE224774T1 (de) * 1995-06-06 2002-10-15 Orchid Biosciences Inc Herstellung elektrischer leitungen durch löcher
US5961800A (en) * 1997-05-08 1999-10-05 Sarnoff Corporation Indirect electrode-based pumps
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US6019882A (en) * 1997-06-25 2000-02-01 Sandia Corporation Electrokinetic high pressure hydraulic system
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US20030055380A1 (en) * 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
EP1556612B1 (fr) * 2002-10-18 2008-12-03 Eksigent Technologie, LLC Appareils electrocinetiques

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4140122A (en) * 1976-06-11 1979-02-20 Siemens Aktiengesellschaft Implantable dosing device
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6409698B1 (en) * 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
US20030232203A1 (en) * 2002-01-18 2003-12-18 The Regents Of The University Of Michigan Porous polymers: compositions and uses thereof
US6719535B2 (en) * 2002-01-31 2004-04-13 Eksigent Technologies, Llc Variable potential electrokinetic device

Non-Patent Citations (1)

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Title
See also references of EP1740497A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9416777B2 (en) 2014-09-26 2016-08-16 Becton, Dickinson And Company Control circuits for electrochemical pump with E-valves

Also Published As

Publication number Publication date
CA2564800C (fr) 2014-04-15
JP4646976B2 (ja) 2011-03-09
CN101365885B (zh) 2011-08-03
EP1740497A2 (fr) 2007-01-10
AU2005245347A1 (en) 2005-12-01
JP2008504794A (ja) 2008-02-14
CA2564800A1 (fr) 2005-12-01
CN101365885A (zh) 2009-02-11
EP1740497A4 (fr) 2015-11-11
WO2005113419A2 (fr) 2005-12-01

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