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WO2005110360A3 - Compositions for injection - Google Patents

Compositions for injection Download PDF

Info

Publication number
WO2005110360A3
WO2005110360A3 PCT/EP2005/005365 EP2005005365W WO2005110360A3 WO 2005110360 A3 WO2005110360 A3 WO 2005110360A3 EP 2005005365 W EP2005005365 W EP 2005005365W WO 2005110360 A3 WO2005110360 A3 WO 2005110360A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
injection
composition
intramuscular
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2005/005365
Other languages
French (fr)
Other versions
WO2005110360A2 (en
Inventor
Steve Leigh
Mathew Louis Steven Leigh
Hoogevest Peter Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phares Pharmaceutical Research NV
Original Assignee
Phares Pharmaceutical Research NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phares Pharmaceutical Research NV filed Critical Phares Pharmaceutical Research NV
Publication of WO2005110360A2 publication Critical patent/WO2005110360A2/en
Publication of WO2005110360A3 publication Critical patent/WO2005110360A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to a homogeneous pharmaceutical composition for the gradual release of biologically active compounds after intramuscular or subcutaneous administration comprising at least one membrane lipid which is in the liquid crystalline state and a process for the preparation of said composition.
PCT/EP2005/005365 2004-05-18 2005-05-17 Compositions for injection Ceased WO2005110360A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04252942 2004-05-18
EP04252942.0 2004-05-18

Publications (2)

Publication Number Publication Date
WO2005110360A2 WO2005110360A2 (en) 2005-11-24
WO2005110360A3 true WO2005110360A3 (en) 2006-04-06

Family

ID=35394648

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/005365 Ceased WO2005110360A2 (en) 2004-05-18 2005-05-17 Compositions for injection

Country Status (1)

Country Link
WO (1) WO2005110360A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101494594B1 (en) 2011-08-30 2015-02-23 주식회사 종근당 Sustained-release lipid pre-concentrate of pharmacologically active substance and pharmaceutical composition comprising the same
WO2014016428A1 (en) 2012-07-26 2014-01-30 Camurus Ab Opioid formulations
DK2877155T3 (en) 2012-07-26 2021-01-18 Camurus Ab OPIOID FORMULATIONS
KR101586790B1 (en) 2012-12-28 2016-01-19 주식회사 종근당 Sustained-release lipid pre-concentrate of anionic pharmacologically active substances and pharmaceutical composition comprising the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004611A (en) * 1984-03-08 1991-04-02 Phares Pharmaceutical Research Nv Pro-liposome compositions
EP0648494A1 (en) * 1993-09-30 1995-04-19 American Home Products Corporation Rapamycin formulations for oral administration
US6599527B1 (en) * 1997-06-20 2003-07-29 Phares Pharmaceutical Research N.V. Preparation of pharmaceutical compositions
US6605298B1 (en) * 1998-03-05 2003-08-12 Phares Pharmaceutical Research N.V. Pharmaceutical compositions and their use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004611A (en) * 1984-03-08 1991-04-02 Phares Pharmaceutical Research Nv Pro-liposome compositions
EP0648494A1 (en) * 1993-09-30 1995-04-19 American Home Products Corporation Rapamycin formulations for oral administration
US6599527B1 (en) * 1997-06-20 2003-07-29 Phares Pharmaceutical Research N.V. Preparation of pharmaceutical compositions
US6605298B1 (en) * 1998-03-05 2003-08-12 Phares Pharmaceutical Research N.V. Pharmaceutical compositions and their use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MURTHA J L ET AL: "SYNTHESIS OF THE CHOLESTERYL ESTER PRODRUGS CHOLESTERYL IBUPROFEN AND CHOLESTERYL FLUFENAMATE AND THEIR FORMULATION INTO PHOSPHOLIPID MICROEMULSIONS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION. WASHINGTON, US, vol. 83, no. 9, 1 September 1994 (1994-09-01), pages 1222 - 1228, XP000465804, ISSN: 0022-3549 *

Also Published As

Publication number Publication date
WO2005110360A2 (en) 2005-11-24

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