WO2005102191B1 - Electro-stimulation and medical delivery device - Google Patents
Electro-stimulation and medical delivery deviceInfo
- Publication number
- WO2005102191B1 WO2005102191B1 PCT/US2005/013203 US2005013203W WO2005102191B1 WO 2005102191 B1 WO2005102191 B1 WO 2005102191B1 US 2005013203 W US2005013203 W US 2005013203W WO 2005102191 B1 WO2005102191 B1 WO 2005102191B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sleeve
- bone
- partially
- implant
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Abstract
A prosthetic screw for at least partial insertion into a bone and/or cartilage. The prosthetic screw includes a head and a lower portion connected to the head. The lower portion includes at least one interface that designed to at least partially discharge an electrical current, and/or a medical substance to or adjacent to the bone and/or cartilage.
Claims
1. A bone implant system comprising a sleeve and an implant, said implant including a bone screw, nail or post, said sleeve designed for at least partial insertion into a bone and/or cartilage, said sleeve including a cavity designed to at least partially receive said implant, said implant including a head, a lower portion connected to the head and at least one passageway, said implant including an outer surface having at least one access opening connected to said at least one passageway, said at least one access opening enabling electrical current, at least one medical substance or combinations thereof to be discharged from said implant, said sleeve including a chamber designed to at least partially telescopically receive said lower portion of said implant.
2. The bone implant system as defined in claim 1 , wherein said sleeve includes a connector in said chamber to secure said lower portion of said implant in said chamber.
3. The bone implant system as defined in claim 2, wherein said connector in said chamber of said sleeve is rclcasably sccurablc to said lower portion of said implant in said chamber.
4. The bone implant system as defined in claims 1-3, wherein said sleeve includes an outer surface connector designed to engage bone to secure said sleeve in an opening in said bone.
5. The bone implant system as defined in claims 1-4, wherein said sleeve includes at least one opening that provides a passageway between an outer surface of said sleeve and said chamber.
6. The bone implant system as defined in claims 1-5, wherein said sleeve includes a removable cap that at least partially seals said chamber when secured to said sleeve,
7. The bone implant system as defined in claims 1-6, wherein said implant includes an electrical mechanism, a mechanical mechanism or combinations thereof.
8. The bone implant system as defined in claim 7, wherein said implant includes a mechanical mechanism, said mechanical mechanism at least partially causing said at least One medical substance to flow through said at least one passageway and to be discharged out of said at least one access opening, said mechanical mechanism including a valve mechanism, a pump mechanism, a motor mechanism or combinations thereof.
9. The bone implant system as defined in claim 7 or 8, wherein said implant includes an electrical mechanism, said electrical mechanism at least partially causing said electric current to flow through said at least one passageway and to be discharged out of said at least one access opening.
10. The bone implant system as defined in claims 7-9, wherein said mechanical mechanism, said electrical mechanism or combinations thereof is at least partially attached to an outer surface of said head.
11. The bone implant system as defined in claims 7-10, wherein said mechanical mechanism, said electrical mechanism or combinations thereof includes at least one MEMS, said at least one MEMS at least partially controlling a rate of flow of said at least one medical substance, current discharge rate or combinations thereof from said at least one access opening.
12. The bone implant system as defined in claims 7-11, wherein said mechanical mechanism, said electrical mechanism or combinations thereof includes at least one microchip, said at least one microchip at least partially controlling a rate of flow of said at least one medical substance, current discharge rate or combinations thereof from said at least one access opening.
13. The bone implant defined in claims 1-12, wherein said head, said lower portion or combinations thereof at least partially includes a coating material, said coating material including a compound that facilitates in the insertion and/or securing of the lower portion in said bone and/or cartilage, promotes and/or inhibits bone and/or other tissue growth, inhibits rejection of said implant, inhibits rejection of components connected to and/or located adjacent to said implant, reduces infection, reduces inflammation, reduces pain, promotes healing of surrounding tissue, combats cancer and/or other diseases, combats biological abnormalities, functions as a location and/or visual indicator or combinations thereof.
14. A method of at least partially inserting an implant into a bone and/or cartilage of a spinal column comprising: a) selecting an implant, said implant including a bone screw, nail or post having a head and a lower portion connected to the head, said implant including a mechanical mechanism, an electrical mechanism or combinations thereof; b) selecting a sleeve that includes a chamber designed to at least partially telescopically receive said lower portion of said implant; c) forming an opening in said bone and/or cartilage of the spinal column; d) at least partially inserting said sleeve into an opening in the bone and/or cartilage of the spinal column; e) allowing said bone and/or cartilage of said spinal column to at least partially grow for a period of time about said sleeve to at least partially anchor said sleeve in said bone and/or cartilage of said spinal column; and, f) at least partially inserting and securing said lower portion of said implant into said chamber of said sleeve after said bone and/or cartilage of said spinal column has at least partially grown about said sleeve to at least partially anchor said sleeve in said bone and/or cartilage of said spinal column.
15. The method as defined in claim 14, wherein said period of time is at least about 1 week.
16. The method as defined in claim 14 or 15, wherein said step of inserting said sleeve is performed on an outpatient basis.
17. A bone implant and a sleeve, said bone implant formed of a screw, nail or post, said sleeve designed for at least partial insertion into a bone or cartilage of a spinal column, said sleeve including a cavity designed to at least partially receive said bone implant, said bone implant comprising a head, a lower portion connected to the head and a mechanical mechanism; said head and said lower portion including an outer surface region, at least a portion of said outer surface region discharging an electrical current, a medical substance, or combinations thereof; said mechanical mechanism at least partially included in said head, at least partially included in said lower portion, at least partially fluidly connected to said head, al least partially lluidly connected to said lower portion, or combinations thereof; said mechanical mechanism designed to at least partially discharge at least one medical substance from a medical substance reservoir to at least a portion of said outer surface region; said mechanical mechanism including a pump and a controller, said controller at least partially controlling a rate at which said pump causes said medical substance to discharge from said outer surface region.
18. The bone implant and a sleeve as defined in claim 25, wherein said controller includes a microchip controller, MEMS controller, or combinations thereof.
19. The bone implant and a sleeve as defined in claim 16 or 18, wherein said mechanical mechanism is at least partially contained in said head, said lower portion, or combinations thereof.
20. The bone implant and a sleeve as defined in claims 17-19, wherein said mechanical mechanism is at least partially dctachably connected to said head, said lower portion, or combinations thereof.
21. The bone implant and a sleeve defined in claims 17-20, including a refilling access opening designed to receive said medical substance for refilling said medical substance reservoir.
22. The bone implant and a sleeve defined in claims 17-21, including a cap or cover that at least partially obstructs said refilling access opening.
23. The bone implant and a sleeve defined in claims 17-22, wherein said medical substance includes at least one antithrombogenic agent, steroid, thioprotese inhibitor, antimicrobial, antibiotic, tissue plasma activator, monoclonal antibody, antifibrosis compound, hormone, anti-mitotic agent, immunosuppressive agent, sense or antisense oligonucleotide, nucleic acid analogue, inhibitor of transcription factor activity, anti-neoplastic compound, chemotherapeutic compound, radioactive agent, growth factor, antiplatelet compound, antitabolite compound, anti-inflammatory compound, anticoagulant compound, antimitotic compound, antioxidant, antimetabolite compound, anti -migratory agent, anti-matrix compound, anti-vital compound, antiproliferative, anti-fungal compound, anti-protozoal compound, human tissue, animal tissue, synthetic tissue, human cells, animal cells, synthetic cells, bone- stimulation matter, bone-growth matter, bone activating matter, or combinations thereof.
24. The bone implant and a sleeve as defined in claims 17-23, wherein said at least one electrical mechanism includes a battery, a generator, or combinations thereof.
25. The bone implant and a sleeve as defined in claims 17-24, wherein said at least one electrical mechanism includes a controller to at least partially control a rate of electrical discharge on a portion of said outer surface region of said implant, said controller including a microchip, MEMS, or combinations thereof.
26. The bone implant and a sleeve defined in claims 17-25, wherein at least, a portion of said outer surface region including a coating material, said coating material including a compound that inhibits bone and other tissue growth, inhibits rejection of said implant, inhibits rejection of components connected to or located adjacent to said implant, reduces infection, reduces inflammation, reduces pain, combats diseases, combats biological abnormalities, functions as a location or visual indicator, or combinations thereof.
27. A bone implant system for insertion or at least partial insertion into a bone or cartilage of a spinal column, said bone implant system comprising a sleeve and a bone implant adapted to be at least partially inserted in a chamber in said sleeve, said chamber in said sleeve including an opening in a top portion of said sleeve, said chamber including a connector to at least partially secure said bone implant in said opening, said bone implant comprising a screw, a nail, a post, a rod , a plate, a shaft or combinations thereof, said bone implant comprising a lower portion adapted to be at least partially inserted in said chamber of said sleeve.
28. The bone implant system as defined in claim 27, wherein said connector in said chamber of said sleeve includes a thread.
29. The bone implant system as defined in claim 27 or 28, wherein said chamber of said sleeve has a generally circular cross-sectional shape.
30. The bone implant system as defined in claims 27-29, wherein said chamber of said sleeve partially extends though said sleeve.
31. The bone implant system as defined in claims 27-30, wherein said sleeve includes an outer surface connector designed to engage and at least partially secure said sleeve to said spinal column.
32. The bone implant system as defined in claims 27-31 , wherein said outer surface connector includes a thread.
33. The bone implant system as defined in claims 27-32, wherein said sleeve includes an outer surface, said outer surface including at least one opening that provides a passageway between said outer surface of said sleeve and said chamber.
34. The bone implant system as defined in claims 27-33, wherein said outer surface includes a plurality of openings that provide passageways between said outer surface of said sleeve and said chamber.
35. The bone implant system as defined in claims 27-34, wherein said sleeve has a generally circular cross-sectional shape.
36. The bone implant system as defined in claims 27-35, including a cap designed to be releasably connected to at least a portion of said chamber of said sleeve, said cap adapted to at least partially facilitate in the connection of said sleeve to said spinal column.
37. The bone implant system as defined in claim 36, wherein said cap includes an outer surface, said outer surface including a thread.
38. The bone implant system as defined in claim 36 or 37, wherein said cap is designed to at least partially seal a portion of said chamber in said sleeve.
39. A method of at least partially inserting an implant into a bone and/or cartilage of a spinal column comprising: a) selecting a bone implant, said bone implant comprising a screw, a nail, a post, a rod, a plate, a shaft or combinations thereof having a head and a lower portion connected to the head; b) selecting a sleeve that includes a chamber designed to at least partially telescopically receive said lower portion of said implant, said chamber in said sleeve including an opening in a top portion of said sleeve, said chamber including a connector to at least partially secure said bone implant in said chamber; c) forming an opening in said bone and/or cartilage of the spinal column; d) at least partially inserting said sleeve into an opening in the bone and/or cartilage of the spinal column; e) allowing said bone and/or cartilage of said spinal column for a period of time to at least partially grow about said sleeve to at least partially anchor said sleeve in said bone and/or cartilage of said spinal column, said period of time at least one week; and, f) at least partially inserting and securing said lower portion of said implant into said chamber of said sleeve after said bone and/or cartilage of said spinal column has at least partially grown about said sleeve to at least partially anchor said sleeve in said bone and/or cartilage of said spinal column.
40. The method as defined in claim 39, wherein said sleeve includes a removable cap to at least partially cover said opening of said chamber and including the steps of maintaining said cap on said sleeve for said period of time to inhibit bone and/or cartilage growth in said chamber and removing said cap prior to said step of at least partially inserting and securing said lower portion of said implant into said chamber of said sleeve.
41. The method as defined in claim 39 or 40, wherein said connector in said chamber of said sleeve includes a thread.
42. The method as defined in claims 39-41, wherein said chamber of said sleeve has a generally circular cross-sectional shape,
43. The method as defined in claim 42, wherein said chamber of said sleeve partially extends though said sleeve.
44. The method as defined in claim 42 or 43, wherein said sleeve includes an outer surface connector designed to engage and at least partially secure said sleeve to said spinal column.
45. The method as defined in claim 44, wherein said outer surface connector includes a thread.
46. The method as defined in claims 42-45, wherein said sleeve includes an outer surface, said outer surface including at least one opening that provides a passageway between said outer surface of said sleeve and said chamber.
47. The method as defined in claim 46, wherein said outer surface includes a plurality of openings that provide passageways between said outer surface of said sleeve and said chamber.
48. The method as defined in claim 42-47, wherein said sleeve has a generally circular cross-sectional shape.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05742873A EP1768583A4 (en) | 2004-04-20 | 2005-04-19 | Electro-stimulation and medical delivery device |
| CA2563653A CA2563653C (en) | 2004-04-20 | 2005-04-19 | Electro-stimulation and medical delivery device |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/828,150 | 2004-04-20 | ||
| US10/828,150 US7615070B2 (en) | 2002-10-11 | 2004-04-20 | Electro-stimulation and medical delivery device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2005102191A2 WO2005102191A2 (en) | 2005-11-03 |
| WO2005102191A3 WO2005102191A3 (en) | 2006-01-12 |
| WO2005102191B1 true WO2005102191B1 (en) | 2006-03-09 |
Family
ID=35197471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2005/013203 Ceased WO2005102191A2 (en) | 2004-04-20 | 2005-04-19 | Electro-stimulation and medical delivery device |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7615070B2 (en) |
| EP (1) | EP1768583A4 (en) |
| CA (1) | CA2563653C (en) |
| WO (1) | WO2005102191A2 (en) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7615070B2 (en) | 2002-10-11 | 2009-11-10 | Spineco, Inc. | Electro-stimulation and medical delivery device |
| US8070785B2 (en) * | 2003-09-16 | 2011-12-06 | Spineco, Inc. | Bone anchor prosthesis and system |
| US7618442B2 (en) | 2003-10-21 | 2009-11-17 | Theken Spine, Llc | Implant assembly and method for use in an internal structure stabilization system |
| US20060004431A1 (en) * | 2004-07-01 | 2006-01-05 | Fuller Thomas A | Prophylactic bactericidal implant |
| WO2006031397A1 (en) * | 2004-09-14 | 2006-03-23 | Spineco, Inc. | Implant device |
| WO2006039636A2 (en) * | 2004-10-01 | 2006-04-13 | Simmons Edward D | Screw sleeve made of polyetheretherketone (peek) |
| US7569061B2 (en) | 2004-11-16 | 2009-08-04 | Innovative Spinal Technologies, Inc. | Off-axis anchor guidance system |
| JP4709892B2 (en) * | 2005-03-24 | 2011-06-29 | シンセス ゲゼルシャフト ミット ベシュレンクテル ハフツング | Bone implant adhesion enhancer |
| US8251902B2 (en) * | 2005-10-17 | 2012-08-28 | Lanx, Inc. | Pedicle guided retractor system |
| US20070118134A1 (en) * | 2005-10-17 | 2007-05-24 | Jeffery Thramann | Surgical Tools and method to facilitate spinal surgery |
| WO2007106774A2 (en) * | 2006-03-13 | 2007-09-20 | The Johns Hopkins University | Orthopedic screw system |
| US8900321B2 (en) * | 2006-03-20 | 2014-12-02 | Zimmer, Inc. | Implant anchoring device |
| WO2007116090A1 (en) * | 2006-04-12 | 2007-10-18 | Novo Nordisk A/S | Absolute position determination of movably mounted member in medication delivery device |
| DE102006018191B4 (en) * | 2006-04-19 | 2008-08-07 | Neue Magnetodyn Gmbh | Electric intramedullary nail system |
| US8372126B2 (en) * | 2006-04-21 | 2013-02-12 | Warsaw Orthopedic, Inc. | Surgical fasteners with mechanical and osteogenic fixation means |
| US8609036B2 (en) | 2006-12-28 | 2013-12-17 | Agentumcidalelectrics, Inc. | Ex vivo antimicrobial devices and methods |
| US8551124B2 (en) | 2007-04-20 | 2013-10-08 | Stryker Trauma Gmbh | Implantation pin, fixation device and method for implanting the implantation pin |
| US20090062914A1 (en) * | 2007-08-29 | 2009-03-05 | Marino James F | Devices and methods for intervertebral therapy |
| AU2009298554B2 (en) | 2008-10-01 | 2016-03-31 | Sherwin Hua | System and method for wire-guided pedicle screw stabilization of spinal vertebrae |
| EP2174607B1 (en) * | 2008-10-10 | 2014-05-07 | Stryker Trauma GmbH | Implantation pin kit and method for implanting an implantation pin |
| TR201808203T4 (en) | 2008-11-06 | 2018-07-23 | Novo Nordisk As | Electronic assisted drug delivery device. |
| US8333791B2 (en) * | 2009-04-24 | 2012-12-18 | Warsaw Orthopedic, Inc. | Medical implant with tie configured to deliver a therapeutic substance |
| US20100274295A1 (en) * | 2009-04-24 | 2010-10-28 | Warsaw Orthopedic, Inc. | Medical implant configured to deliver a therapeutic substance |
| EP2515750A4 (en) | 2009-12-21 | 2013-07-10 | Sherwin Hua | Insertion of medical devices through non-orthogonal and orthogonal trajectories within the cranium and methods of using |
| KR20140005162A (en) * | 2010-10-25 | 2014-01-14 | 보그단 콘스탄틴 브라딜라 | Electro-magnetic cellular treatment |
| CN104902843B (en) * | 2012-11-14 | 2020-01-14 | 赛福马有限责任公司 | Treatment member and treatment system for a dental implant assembly |
| CN104799923A (en) * | 2015-04-30 | 2015-07-29 | 中国人民解放军第二军医大学 | Strutting bone grafting instrument for compression fracture of vertebral body |
| US10052140B2 (en) | 2016-10-05 | 2018-08-21 | Stryker European Holdings I, Llc | Apparatus and method for fenestrated screw augmentation |
| US11351381B2 (en) | 2018-05-18 | 2022-06-07 | Washington University | Systems and methods for stimulating sympathetic nervous system |
| US11160580B2 (en) | 2019-04-24 | 2021-11-02 | Spine23 Inc. | Systems and methods for pedicle screw stabilization of spinal vertebrae |
| CN115551426B (en) | 2019-11-27 | 2025-11-28 | 斯拜因23公司 | Systems, devices, and methods for treating scoliosis |
| EP4297674A1 (en) | 2021-02-23 | 2024-01-03 | NuVasive Specialized Orthopedics, Inc. | Adjustable implant, system and methods |
| EP4337119A1 (en) | 2021-05-12 | 2024-03-20 | Spine23 Inc. | Systems and methods for pedicle screw stabilization of spinal vertebrae |
| AU2022316483A1 (en) * | 2021-07-19 | 2024-01-25 | Ossio Ltd. | Fiber-reinforced biocomposite medical implants with deformable protrusions and methods of use thereof |
| US12458417B2 (en) | 2022-08-15 | 2025-11-04 | Nuvasive Specialized Orthopedics Inc. | Intermedullary lengthening implant with integrated load sensor |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2311817C2 (en) | 1973-03-09 | 1984-06-07 | Werner Dipl.-Ing. 8000 München Kraus | Stimulation current device to promote the healing of bone damage |
| US4351337A (en) | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
| US4027392A (en) | 1976-05-10 | 1977-06-07 | Interface Biomedical Laboratories Corporation | Endosteal bionic tooth and implantation method |
| DE2742741A1 (en) | 1977-09-22 | 1979-04-05 | Kraus Werner | ADDITIONAL DEVICE FOR ATTACHING A PICKUP COIL AND ELECTRODE CONNECTORS TO AN OSTEOSYNTHESIS IMPLANT |
| US4378224A (en) * | 1980-09-19 | 1983-03-29 | Nimni Marcel E | Coating for bioprosthetic device and method of making same |
| US4359318A (en) | 1981-12-18 | 1982-11-16 | Neal Gittleman | Dental implant |
| US4523910A (en) | 1983-01-31 | 1985-06-18 | Makovich Joseph J | Method and apparatus for injecting medication into a body through a tooth |
| CA1227902A (en) | 1984-04-02 | 1987-10-13 | Raymond G. Tronzo | Fenestrated hip screw and method of augmented internal fixation |
| US4640271A (en) | 1985-11-07 | 1987-02-03 | Zimmer, Inc. | Bone screw |
| US4701180A (en) | 1986-02-19 | 1987-10-20 | Kelly L Thomas | Implanted anchor and insert with analog display |
| IT1214567B (en) | 1986-12-02 | 1990-01-18 | Cremascoli G S P A | ENDOMIDOLLAR NAIL STRUCTURE, AND EQUIPMENT FOR ITS INSERTION INTO THE BONE. |
| WO1988006023A1 (en) * | 1987-02-20 | 1988-08-25 | Klaus Draenert | Suction drainage-bone screw |
| DE3708133A1 (en) | 1987-03-13 | 1988-09-22 | Bisping Hans Juergen | IMPLANTABLE ELECTRODE PROBE WITH EXTENDABLE SCREW ELECTRODE |
| US4781591A (en) | 1987-04-06 | 1988-11-01 | Allen James P | Endosteal implant and method for performing implantation thereof |
| US6120502A (en) * | 1988-06-13 | 2000-09-19 | Michelson; Gary Karlin | Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis |
| FR2642643B1 (en) | 1989-02-09 | 1991-05-10 | Vignaud Jean Louis | SPINAL INSTRUMENTATION FOR UNIVERSAL PEDICULAR FIXATION WITH MICROMETRIC ADJUSTMENT DIAPASON SCREW |
| US5236456A (en) * | 1989-11-09 | 1993-08-17 | Osteotech, Inc. | Osteogenic composition and implant containing same |
| US5129900B1 (en) | 1990-07-24 | 1998-12-29 | Acromed Corp | Spinal column retaining method and apparatus |
| DE4107480C2 (en) | 1991-03-08 | 1994-09-22 | Heinrich Ulrich | Pedicle screw for implants to correct and stabilize the spine |
| US5868711A (en) * | 1991-04-29 | 1999-02-09 | Board Of Regents, The University Of Texas System | Implantable intraosseous device for rapid vascular access |
| EP0553424A1 (en) | 1992-01-30 | 1993-08-04 | Acromed Corporation | Spinal column retaining apparatus |
| US5292252A (en) | 1992-12-14 | 1994-03-08 | Impla-Med, Inc. | Stimulator healing cap |
| US5387212A (en) | 1993-01-26 | 1995-02-07 | Yuan; Hansen A. | Vertebral locking and retrieving system with central locking rod |
| SE9301406D0 (en) | 1993-04-27 | 1993-04-27 | Medevelop Ab | FOE IMPLANTATION IN THE WEBSITE PROVIDED FOR THE HALLAR ORGAN FOR CONTROLLED RECORDING AND LOCATION FIXING OF WIRELESS WIRES FOR ELECTRIC INFORMATION TRANSFER USEFUL EQUIPMENT AND SET FOR ITS APPLICATION |
| US5584688A (en) | 1994-03-22 | 1996-12-17 | Sangi Co., Ltd. | Medicine injection device |
| US6004322A (en) | 1994-10-25 | 1999-12-21 | Sdgi Holdings, Inc. | Modular pedicle screw system |
| PT788351E (en) | 1994-11-10 | 2003-06-30 | Univ Kentucky Res Foundation T | LIBERTACAOCONTROLADA RECHARGEABLE IMPLANTABLE DEVICE FOR ADMINISTERING MEDICATIONS DIRECTLY ON AN INTERNAL PORTION OF THE BODY |
| US5882350A (en) | 1995-04-13 | 1999-03-16 | Fastenetix, Llc | Polyaxial pedicle screw having a threaded and tapered compression locking mechanism |
| US6340588B1 (en) | 1995-04-25 | 2002-01-22 | Discovery Partners International, Inc. | Matrices with memories |
| US5571139A (en) | 1995-05-19 | 1996-11-05 | Jenkins, Jr.; Joseph R. | Bidirectional suture anchor |
| US5683391A (en) | 1995-06-07 | 1997-11-04 | Danek Medical, Inc. | Anterior spinal instrumentation and method for implantation and revision |
| US5871484A (en) * | 1995-11-09 | 1999-02-16 | General Orthopedics | Apparatus and method for administering a biologically active substance to a bone |
| DE19544750A1 (en) | 1995-11-30 | 1997-06-05 | Christoph Rehberg | Implantable device with internal electrode to promote tissue growth |
| US5725377A (en) | 1996-03-29 | 1998-03-10 | Lemler; Jeffrey Richard | Dental implant apparatus |
| US5879350A (en) | 1996-09-24 | 1999-03-09 | Sdgi Holdings, Inc. | Multi-axial bone screw assembly |
| US5968098A (en) | 1996-10-22 | 1999-10-19 | Surgical Dynamics, Inc. | Apparatus for fusing adjacent bone structures |
| US6485494B1 (en) | 1996-12-20 | 2002-11-26 | Thomas T. Haider | Pedicle screw system for osteosynthesis |
| US6224596B1 (en) | 1997-01-06 | 2001-05-01 | Roger P. Jackson | Set screw for use with osteosynthesis apparatus |
| US5872426A (en) | 1997-03-18 | 1999-02-16 | Stevens Institute Of Technology | Glow plasma discharge device having electrode covered with perforated dielectric |
| US5785711A (en) | 1997-05-15 | 1998-07-28 | Third Millennium Engineering, Llc | Polyaxial pedicle screw having a through bar clamp locking mechanism |
| US5810819A (en) | 1997-05-15 | 1998-09-22 | Spinal Concepts, Inc. | Polyaxial pedicle screw having a compression locking rod gripping mechanism |
| IL124529A (en) | 1997-05-20 | 2001-08-08 | Akiva Raphael Katz | Pedicle screw assembly |
| FR2768610B1 (en) | 1997-09-22 | 1999-12-10 | Materiel Orthopedique En Abreg | BONE SCREW FOR OSTEOSYNTHESIS DEVICES, AND METHOD FOR MANUFACTURING THE SAME |
| DE29806563U1 (en) | 1998-04-09 | 1998-06-18 | Howmedica GmbH, 24232 Schönkirchen | Pedicle screw and assembly aid for it |
| EP1075224B1 (en) | 1998-04-29 | 2003-03-05 | Dimso (Distribution Medicale du Sud-Ouest) | Backbone osteosynthesis system with clamping means in particular for anterior fixing |
| US6113601A (en) | 1998-06-12 | 2000-09-05 | Bones Consulting, Llc | Polyaxial pedicle screw having a loosely coupled locking cap |
| US6056753A (en) | 1998-07-13 | 2000-05-02 | Jackson; Roger P. | Set screw for use with osteosynthesis apparatus |
| US6669697B1 (en) | 1998-09-25 | 2003-12-30 | Perumala Corporation | Self-retaining bolt for internal spinal stabilizers |
| TW490860B (en) * | 1998-12-24 | 2002-06-11 | United Microelectronics Corp | Manufacturing of flash memory cell |
| EP1148830A1 (en) | 1999-02-04 | 2001-10-31 | Synthes Ag Chur | Bone screw |
| FR2792521B1 (en) | 1999-04-22 | 2001-08-31 | New Deal | COMPRESSION OSTEOSYNTHESIS SCREWS AND IMPLEMENTATION ANCILLARY |
| DE19922440A1 (en) | 1999-05-06 | 2000-11-09 | Schaefer Micomed Gmbh | Pedicle screw |
| SE514342C2 (en) * | 1999-05-31 | 2001-02-12 | Nobel Biocare Ab | Method, apparatus and use in implants to ensure delivery of bioactive substance to the surrounding bone and / or tissue of the implant |
| DE19928449C1 (en) * | 1999-06-23 | 2001-03-08 | Geot Ges Fuer Elektro Oseto Th | Bone screw with device for electrical stimulation |
| US7090668B1 (en) * | 1999-10-29 | 2006-08-15 | Cytori Therapeutics, Inc. | Time-released substance delivery device |
| DE59901090D1 (en) | 1999-12-23 | 2002-05-02 | Storz Karl Gmbh & Co Kg | Decentralized drive screw |
| DE10005385A1 (en) | 2000-02-07 | 2001-08-09 | Ulrich Gmbh & Co Kg | Pedicle screw |
| US6375657B1 (en) | 2000-03-14 | 2002-04-23 | Hammill Manufacturing Co. | Bonescrew |
| US6565572B2 (en) | 2000-04-10 | 2003-05-20 | Sdgi Holdings, Inc. | Fenestrated surgical screw and method |
| US6554830B1 (en) | 2000-04-10 | 2003-04-29 | Sdgi Holdings, Inc. | Fenestrated surgical anchor and method |
| EP1311191B1 (en) | 2000-08-25 | 2012-03-07 | The Cleveland Clinic Foundation | Implantable apparatus for assessing loads on adjacent pair of vertebrae |
| US6804552B2 (en) | 2000-11-03 | 2004-10-12 | Medtronic, Inc. | MEMs switching circuit and method for an implantable medical device |
| US6454807B1 (en) | 2000-11-30 | 2002-09-24 | Roger P. Jackson | Articulated expandable spinal fusion cage system |
| US6802844B2 (en) | 2001-03-26 | 2004-10-12 | Nuvasive, Inc | Spinal alignment apparatus and methods |
| US6843790B2 (en) | 2001-03-27 | 2005-01-18 | Bret A. Ferree | Anatomic posterior lumbar plate |
| US6511481B2 (en) * | 2001-03-30 | 2003-01-28 | Triage Medical, Inc. | Method and apparatus for fixation of proximal femoral fractures |
| US6610096B2 (en) * | 2001-08-22 | 2003-08-26 | Macdonald Stuart G. | Prosthetic implants having enhanced utility |
| US20030055380A1 (en) * | 2001-09-19 | 2003-03-20 | Flaherty J. Christopher | Plunger for patient infusion device |
| US6654629B2 (en) | 2002-01-23 | 2003-11-25 | Valentino Montegrande | Implantable biomarker and method of use |
| US7615070B2 (en) | 2002-10-11 | 2009-11-10 | Spineco, Inc. | Electro-stimulation and medical delivery device |
| US20040073221A1 (en) | 2002-10-11 | 2004-04-15 | Spineco, Inc., A Corporation Of Ohio | Electro-stimulation and medical delivery device |
| US8070785B2 (en) | 2003-09-16 | 2011-12-06 | Spineco, Inc. | Bone anchor prosthesis and system |
| WO2006031397A1 (en) | 2004-09-14 | 2006-03-23 | Spineco, Inc. | Implant device |
-
2004
- 2004-04-20 US US10/828,150 patent/US7615070B2/en not_active Expired - Fee Related
-
2005
- 2005-04-19 CA CA2563653A patent/CA2563653C/en not_active Expired - Fee Related
- 2005-04-19 WO PCT/US2005/013203 patent/WO2005102191A2/en not_active Ceased
- 2005-04-19 EP EP05742873A patent/EP1768583A4/en not_active Withdrawn
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