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WO2005019803A3 - Measuring analytes from an electromagnetic spectrum using a wavelength router - Google Patents

Measuring analytes from an electromagnetic spectrum using a wavelength router Download PDF

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Publication number
WO2005019803A3
WO2005019803A3 PCT/US2004/027391 US2004027391W WO2005019803A3 WO 2005019803 A3 WO2005019803 A3 WO 2005019803A3 US 2004027391 W US2004027391 W US 2004027391W WO 2005019803 A3 WO2005019803 A3 WO 2005019803A3
Authority
WO
WIPO (PCT)
Prior art keywords
electromagnetic spectrum
measuring
wavelength router
measuring analytes
sample volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/027391
Other languages
French (fr)
Other versions
WO2005019803A2 (en
Inventor
Jan Lipson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C8
Original Assignee
C8
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C8 filed Critical C8
Priority to CN2004800241479A priority Critical patent/CN1838911B/en
Priority to KR1020067003658A priority patent/KR101103091B1/en
Priority to EP04781974A priority patent/EP1662986A4/en
Publication of WO2005019803A2 publication Critical patent/WO2005019803A2/en
Publication of WO2005019803A3 publication Critical patent/WO2005019803A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/30Measuring the intensity of spectral lines directly on the spectrum itself
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0229Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using masks, aperture plates, spatial light modulators or spatial filters, e.g. reflective filters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0205Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0232Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using shutters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12Generating the spectrum; Monochromators
    • G01J3/18Generating the spectrum; Monochromators using diffraction elements, e.g. grating
    • G01J3/1838Holographic gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/42Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/42Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/427Dual wavelengths spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03HHOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005Adaptation of holography to specific applications

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Weak signals scattered from analytes at multiple wavelengths can be summed to illuminate either a single detector or a multiplicity of detectors, offering the possibility of concentrating the spectral energy on a smaller total detector area. In addition, a method is disclosed whereby a calibration of the resulting signal for a given analyte can be obtained by means of measuring the quantity of water in the sample volume and by means of measuring the salinity of the fluid in the sample volume.
PCT/US2004/027391 2003-08-22 2004-08-23 Measuring analytes from an electromagnetic spectrum using a wavelength router Ceased WO2005019803A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN2004800241479A CN1838911B (en) 2003-08-22 2004-08-23 Measuring analytes from the electromagnetic spectrum using wavelength routers
KR1020067003658A KR101103091B1 (en) 2003-08-22 2004-08-23 Measurement of Samples from the Electromagnetic Spectrum Using Wavelength Routers
EP04781974A EP1662986A4 (en) 2003-08-22 2004-08-23 Measuring analytes from an electromagnetic spectrum using a wavelength router

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49707203P 2003-08-22 2003-08-22
US60/497,072 2003-08-22
US10/923,264 2004-08-20
US10/923,264 US7266401B2 (en) 2003-08-22 2004-08-20 Measuring analytes from an electromagnetic spectrum using a wavelength router

Publications (2)

Publication Number Publication Date
WO2005019803A2 WO2005019803A2 (en) 2005-03-03
WO2005019803A3 true WO2005019803A3 (en) 2005-10-20

Family

ID=34221437

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/027391 Ceased WO2005019803A2 (en) 2003-08-22 2004-08-23 Measuring analytes from an electromagnetic spectrum using a wavelength router

Country Status (5)

Country Link
US (2) US7266401B2 (en)
EP (1) EP1662986A4 (en)
KR (1) KR101103091B1 (en)
CN (1) CN1838911B (en)
WO (1) WO2005019803A2 (en)

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* Cited by examiner, † Cited by third party
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WO2007056225A2 (en) * 2005-11-09 2007-05-18 Cas Medical Systems, Inc. Calibration device for a spectrophotometric system
US7228634B1 (en) * 2005-12-19 2007-06-12 Palo Alto Research Center Inc. Using viewing-angle-sensitive visual tags to determine angular orientation and/or location
FR2929011B1 (en) * 2008-03-20 2013-01-04 Commissariat Energie Atomique METHOD AND DEVICE FOR HIGH QUANTITATIVE QUANTITATIVE MEASUREMENT OF BIOMOLECULAR TARGETS PRESENTED ON OR IN A BIOLOGICAL ANALYSIS MEDIUM.
CA2726421C (en) * 2008-06-05 2017-11-07 Perkinelmer Health Sciences, Inc. Optical devices and systems using them
US20100112614A1 (en) * 2008-11-06 2010-05-06 Physical Logic Ag Coupled Antenna Impedance Spectroscopy
US9285575B2 (en) * 2009-01-26 2016-03-15 President And Fellows Of Harvard College Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping
GB201000179D0 (en) 2010-01-07 2010-02-24 Rsp Systems As Apparatus for non-invasive in vivo measurement by raman spectroscopy
WO2012128614A1 (en) * 2011-03-24 2012-09-27 Erasmus University Medical Center Rotterdam Method to determine the absorption coefficient in turbid media
US8411265B2 (en) * 2011-06-14 2013-04-02 C8 Medisensors Inc. Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation
US8781547B2 (en) * 2011-10-28 2014-07-15 Medtronic, Inc. Method and apparatus for calibrating an absolute oxygen saturation sensor
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
US9829378B1 (en) * 2016-10-13 2017-11-28 Bentley Instruments, Inc. Determining a size of cell of a transmission spectroscopy device
CN106770181A (en) * 2017-02-24 2017-05-31 天津大学 A kind of multifocal point type Raman spectrum Acquisition Instrument based on diffraction optical element
WO2022031458A1 (en) * 2020-08-03 2022-02-10 Siemens Healthcare Diagnostics Inc. Absorbance spectroscopy analyzer and method of use
JP1732281S (en) * 2022-01-07 2022-12-15 Raman microscope

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011284A (en) * 1990-03-22 1991-04-30 Kaiser Optical Systems Detection system for Raman scattering employing holographic diffraction
US5331958A (en) * 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
US5370114A (en) * 1992-03-12 1994-12-06 Wong; Jacob Y. Non-invasive blood chemistry measurement by stimulated infrared relaxation emission
US6122052A (en) * 1998-04-27 2000-09-19 Perkin Elmer Llc Computer operated spectrometric instrument and associated calculator

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US5026131A (en) * 1988-02-22 1991-06-25 Physical Optics Corporation High channel density, broad bandwidth wavelength division multiplexer with highly non-uniform Bragg-Littrow holographic grating
WO1995031928A1 (en) * 1994-05-20 1995-11-30 Kuenst Hermann Transcutaneous, non-bloody determination of the concentration of substances in the blood
JPH08332181A (en) * 1995-06-09 1996-12-17 Kdk Corp Living body positioning method, living body information measuring positioning apparatus, and living body information measuring apparatus
AP931A (en) * 1995-10-23 2001-02-02 Cytometrics Inc Method and apparatus for reflected imaging analysis.
US6271970B1 (en) * 1997-12-13 2001-08-07 Lightchip, Inc. Wavelength division multiplexing/demultiplexing devices using dual homogeneous refractive index lenses
EP1057290B1 (en) * 1998-02-13 2003-01-08 Apa Optics, Inc. Multiplexer and demultiplexer for single mode optical fiber communication links
DE69903306T2 (en) * 1998-07-07 2003-05-22 Lightouch Medical, Inc. METHOD FOR TISSUE MODULATION FOR QUANTITATIVE NON-INVASIVE IN VIVO SPECTROSCOPIC ANALYSIS OF TISSUE
EP1093343A4 (en) * 1998-07-13 2005-04-27 Los Angeles Childrens Hospital NON-INVASIVE GLUCOSE MEASURING DEVICE
US6205273B1 (en) 1999-03-02 2001-03-20 Lucent Technologies Inc. Waveguide grating router having a predetermined composite amplitude spectrum
US6501877B1 (en) 1999-11-16 2002-12-31 Network Photonics, Inc. Wavelength router
EP1180236A1 (en) * 2000-02-01 2002-02-20 American Holographic, Inc. Holographic grating spectrum analyzer
DE10027100C2 (en) * 2000-05-31 2002-08-08 Klaus Mueller-Dethlefs Method and device for detecting substances in body fluids
US6574490B2 (en) * 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
US7039452B2 (en) * 2002-12-19 2006-05-02 The University Of Utah Research Foundation Method and apparatus for Raman imaging of macular pigments

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011284A (en) * 1990-03-22 1991-04-30 Kaiser Optical Systems Detection system for Raman scattering employing holographic diffraction
US5370114A (en) * 1992-03-12 1994-12-06 Wong; Jacob Y. Non-invasive blood chemistry measurement by stimulated infrared relaxation emission
US5331958A (en) * 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
US6122052A (en) * 1998-04-27 2000-09-19 Perkin Elmer Llc Computer operated spectrometric instrument and associated calculator

Also Published As

Publication number Publication date
CN1838911B (en) 2010-05-05
US20050124870A1 (en) 2005-06-09
EP1662986A2 (en) 2006-06-07
US20070279628A1 (en) 2007-12-06
KR101103091B1 (en) 2012-01-04
KR20070041662A (en) 2007-04-19
WO2005019803A2 (en) 2005-03-03
EP1662986A4 (en) 2010-06-02
US7266401B2 (en) 2007-09-04
CN1838911A (en) 2006-09-27

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