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WO2005009408B1 - Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur - Google Patents

Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur

Info

Publication number
WO2005009408B1
WO2005009408B1 PCT/US2003/034763 US0334763W WO2005009408B1 WO 2005009408 B1 WO2005009408 B1 WO 2005009408B1 US 0334763 W US0334763 W US 0334763W WO 2005009408 B1 WO2005009408 B1 WO 2005009408B1
Authority
WO
WIPO (PCT)
Prior art keywords
dosage form
sustained release
polymer
anesthetic
release dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/034763
Other languages
English (en)
Other versions
WO2005009408A2 (fr
WO2005009408A3 (fr
Filing date
Publication date
Priority claimed from US10/606,969 external-priority patent/US20040001889A1/en
Priority to JP2005504650A priority Critical patent/JP2007521225A/ja
Priority to MXPA05014193A priority patent/MXPA05014193A/es
Priority to EP03778041A priority patent/EP1638519A2/fr
Priority to CA002530357A priority patent/CA2530357A1/fr
Priority to BRPI0318373-4A priority patent/BR0318373A/pt
Application filed filed Critical
Priority to AU2003286826A priority patent/AU2003286826A1/en
Publication of WO2005009408A2 publication Critical patent/WO2005009408A2/fr
Priority to IL172781A priority patent/IL172781A0/en
Anticipated expiration legal-status Critical
Publication of WO2005009408A3 publication Critical patent/WO2005009408A3/fr
Priority to NO20060295A priority patent/NO20060295L/no
Publication of WO2005009408B1 publication Critical patent/WO2005009408B1/fr
Ceased legal-status Critical Current

Links

Abstract

L'invention concerne des systèmes et des trousses d'apport de médicament qui permettent de libérer un anesthésiant tel que la bupivacaïne sur une courte durée. Des procédés d'administration et d'élaboration de tels systèmes sont également prévus. Les systèmes d'apport de médicament comprennent un excipient sous forme de gel de courte durée, et un anesthésiant dissous ou dispersé dans cet excipient. L'excipient gel comprend un polymère de faible poids moléculaire biocompatible et bioérodable, et un solvant non miscible avec l'eau selon une quantité permettant de plastifier le polymère et de former un gel avec celui-ci. Dans certains cas, on utilise un solvant à plusieurs composants avec le solvant non miscible avec l'eau. On peut régler le taux d'efficacité, qui est une façon de mesurer l'efficacité du système d'apport, par exemple selon la construction de l'excipient gel en vue de l'obtention d'un profil de libération voulu.
PCT/US2003/034763 2003-06-25 2003-10-31 Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur Ceased WO2005009408A2 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
MXPA05014193A MXPA05014193A (es) 2003-06-25 2003-10-31 Fomas de dosis de liberacion sostenida de anestesicos para el manejo del dolor.
AU2003286826A AU2003286826A1 (en) 2003-06-25 2003-10-31 Sustained release dosage forms of anesthetics for pain management
EP03778041A EP1638519A2 (fr) 2003-06-25 2003-10-31 Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur
CA002530357A CA2530357A1 (fr) 2003-06-25 2003-10-31 Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur
BRPI0318373-4A BR0318373A (pt) 2003-06-25 2003-10-31 formas de dosagem de liberação sustentada de anestésicos para controle de dor
JP2005504650A JP2007521225A (ja) 2003-06-25 2003-10-31 疼痛を管理するための麻酔薬の徐放性剤形
IL172781A IL172781A0 (en) 2003-06-25 2005-12-22 Sustained release dosage forms of anesthetics for pain management
NO20060295A NO20060295L (no) 2003-06-25 2006-01-20 Doseringsformer med vedvarende frigivning av anestetika for smertehandtering

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/606,969 US20040001889A1 (en) 2002-06-25 2003-06-25 Short duration depot formulations
US10/606,969 2003-06-25

Publications (3)

Publication Number Publication Date
WO2005009408A2 WO2005009408A2 (fr) 2005-02-03
WO2005009408A3 WO2005009408A3 (fr) 2006-01-19
WO2005009408B1 true WO2005009408B1 (fr) 2006-04-06

Family

ID=34103124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/034763 Ceased WO2005009408A2 (fr) 2003-06-25 2003-10-31 Formes pharmaceutiques a liberation prolongee d'anesthesiant pour soulager la douleur

Country Status (17)

Country Link
US (7) US20040001889A1 (fr)
EP (2) EP1638519A2 (fr)
JP (1) JP2007521225A (fr)
KR (1) KR20060109816A (fr)
CN (1) CN1822814A (fr)
AR (1) AR045975A1 (fr)
AU (1) AU2003286826A1 (fr)
BR (1) BR0318373A (fr)
CA (1) CA2530357A1 (fr)
IL (1) IL172781A0 (fr)
MA (1) MA27863A1 (fr)
MX (1) MXPA05014193A (fr)
NO (1) NO20060295L (fr)
PL (1) PL379263A1 (fr)
RU (1) RU2332985C2 (fr)
WO (1) WO2005009408A2 (fr)
ZA (1) ZA200600698B (fr)

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