[go: up one dir, main page]

WO2005096990A3 - Nouvelle modification de protheses medicales - Google Patents

Nouvelle modification de protheses medicales Download PDF

Info

Publication number
WO2005096990A3
WO2005096990A3 PCT/US2005/010944 US2005010944W WO2005096990A3 WO 2005096990 A3 WO2005096990 A3 WO 2005096990A3 US 2005010944 W US2005010944 W US 2005010944W WO 2005096990 A3 WO2005096990 A3 WO 2005096990A3
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutic
medical prostheses
therapeutic agents
treat
additionally
Prior art date
Application number
PCT/US2005/010944
Other languages
English (en)
Other versions
WO2005096990A2 (fr
Inventor
Mohammad David Mansouri
Rabih O Darouiche
Original Assignee
Baylor College Medicine
Mohammad David Mansouri
Rabih O Darouiche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine, Mohammad David Mansouri, Rabih O Darouiche filed Critical Baylor College Medicine
Priority to EP05731606A priority Critical patent/EP1737378A2/fr
Priority to AU2005231417A priority patent/AU2005231417A1/en
Priority to CA002561496A priority patent/CA2561496A1/fr
Publication of WO2005096990A2 publication Critical patent/WO2005096990A2/fr
Publication of WO2005096990A3 publication Critical patent/WO2005096990A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104Silver, e.g. silver sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne l'incorporation d'un ou plusieurs agents thérapeutiques sur des prothèses médicales métalliques et non métalliques. L'agent thérapeutique peut être utilisé, par exemple, pour prévenir, traiter ou réduire les infections bactériennes et fongiques associées à ces implants. En outre, les agents thérapeutiques peuvent être utilisés pour produire d'autres effets thérapeutiques bénéfiques. Plus particulièrement, un revêtement thérapeutique bicouche est appliqué en deux étapes. Par ailleurs, des agents thérapeutiques non antimicrobiens peuvent être incorporés dans ce revêtement en vue du traitement, de la prévention, de la modification ou de la stimulation de certaines bioactivités cliniques.
PCT/US2005/010944 2004-04-02 2005-03-31 Nouvelle modification de protheses medicales WO2005096990A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP05731606A EP1737378A2 (fr) 2004-04-02 2005-03-31 Nouvelle modification de protheses medicales
AU2005231417A AU2005231417A1 (en) 2004-04-02 2005-03-31 Novel modification of medical prostheses
CA002561496A CA2561496A1 (fr) 2004-04-02 2005-03-31 Nouvelle modification de protheses medicales

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55891804P 2004-04-02 2004-04-02
US60/558,918 2004-04-02

Publications (2)

Publication Number Publication Date
WO2005096990A2 WO2005096990A2 (fr) 2005-10-20
WO2005096990A3 true WO2005096990A3 (fr) 2007-02-08

Family

ID=35125588

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/010944 WO2005096990A2 (fr) 2004-04-02 2005-03-31 Nouvelle modification de protheses medicales

Country Status (5)

Country Link
US (1) US7238363B2 (fr)
EP (1) EP1737378A2 (fr)
AU (1) AU2005231417A1 (fr)
CA (1) CA2561496A1 (fr)
WO (1) WO2005096990A2 (fr)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
ATE419880T1 (de) * 2000-06-09 2009-01-15 Baylor College Medicine Kombination von antimikrobiellen wirkstoffen und bakterieller interferenz zum überziehen medizinischer vorrichtungen
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
EP2075014B9 (fr) 2002-05-24 2012-02-01 Angiotech International Ag Compositions et procédés pour le revêtement d'implants médicaux
MX2007010147A (es) * 2005-02-22 2007-10-15 Tim T Nguyen Composicion farmaceutica para el tratamiento de la onicomicosis.
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
US20070134287A1 (en) * 2005-12-09 2007-06-14 Biomet Manufacturing Corp Method for coating biocompatible substrates with antibiotics
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US20070264296A1 (en) * 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US20080046073A1 (en) * 2006-08-16 2008-02-21 Elshire H Donel Non-Coagulative Vascular Shunt
NZ549249A (en) * 2006-08-18 2009-10-30 Univ Massey Methods for reducing the incidence of mastitis by administration of keratin
CN100406073C (zh) * 2006-09-07 2008-07-30 中国人民解放军第二军医大学 放射性纳米涂膜复合支架及其制备方法
CA2916746C (fr) * 2006-10-17 2018-11-27 C.R. Bard, Inc. Systeme de controle de matieres fecales
KR20090100358A (ko) * 2006-11-16 2009-09-23 이-테라퓨틱스 리미티드 스타필로로커스 감염의 치료를 위한 클로트리마졸
EP2508231A3 (fr) * 2006-11-16 2012-10-17 E-Therapeutics Plc Imidazoles pour le traitement des infections bactériennes à résistance multi-médicaments
US8088095B2 (en) * 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
WO2008115536A2 (fr) * 2007-03-20 2008-09-25 Boston Scientific Scimed, Inc. Dispositifs médicaux urologiques pour la libération d'agents thérapeutiques bénéfiques pour la prostate
AU2008228710A1 (en) 2007-03-22 2008-09-25 Novalign Orthopaedics, Inc. Segmented intramedullary structure
US8777912B2 (en) 2007-07-22 2014-07-15 C. R. Bard, Inc. Waste management system
US8706211B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having self-cleaning surfaces
US8460229B2 (en) 2007-08-17 2013-06-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between transmissive and reflective states
US8162924B2 (en) * 2007-08-17 2012-04-24 The Invention Science Fund I, Llc System, devices, and methods including actively-controllable superoxide water generating systems
US8734718B2 (en) 2007-08-17 2014-05-27 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component
US20090048648A1 (en) * 2007-08-17 2009-02-19 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Self-sterilizing device
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US8753304B2 (en) 2007-08-17 2014-06-17 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter
US8702640B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc System, devices, and methods including catheters configured to monitor and inhibit biofilm formation
US8029740B2 (en) * 2008-07-11 2011-10-04 The Invention Science Fund I, Llc Event-triggered self-sterilization of article surfaces
US8647292B2 (en) 2007-08-17 2014-02-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states
US8114346B2 (en) * 2007-08-17 2012-02-14 The Invention Science Fund I, Llc Event-triggered ultraviolet light sterilization of surfaces
DE102007039871A1 (de) * 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
US20090062737A1 (en) * 2007-08-28 2009-03-05 Sun William Y Ice coated hypodermic needle
GB0724996D0 (en) * 2007-12-21 2008-01-30 Therapeutics Ltd E Antibacterial combination therapy for the treatment of gram positive bacterial infections
WO2009126502A2 (fr) * 2008-04-08 2009-10-15 Targanta Therapeutics Corp. Procédés d'inhibition et de traitement de biofilms à l'aide d'antibiotiques glycopeptidiques
CA2727432C (fr) 2008-06-12 2016-10-11 Medtronic Xomed, Inc. Methode de traitement de plaies chroniques a l'aide d'un systeme de solvant de substance polymere extracellulaire
GB0813211D0 (en) 2008-07-18 2008-08-27 E Therapeutics Plc Antibacterial combination therapy for the treatment of gram positive bacterial infections
US10842645B2 (en) 2008-08-13 2020-11-24 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
US9700431B2 (en) 2008-08-13 2017-07-11 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
JP5774989B2 (ja) 2008-08-13 2015-09-09 スメド−ティーエイ/ティーディー・エルエルシー 整形外科用ねじ
US20100042213A1 (en) 2008-08-13 2010-02-18 Nebosky Paul S Drug delivery implants
US9616205B2 (en) 2008-08-13 2017-04-11 Smed-Ta/Td, Llc Drug delivery implants
WO2010025386A1 (fr) 2008-08-29 2010-03-04 Smed-Ta/Td, Llc Implant orthopédique
US8535723B2 (en) 2008-09-23 2013-09-17 Laboratory Skin Care, Inc. Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same
WO2010042427A2 (fr) 2008-10-06 2010-04-15 Microbial Defense Systems, Llc Composition antimicrobienne et ses procédés de fabrication et d'utilisation
US20100094426A1 (en) * 2008-10-14 2010-04-15 Grohowski Jr Joseph A Hybrid intervertebral spinal implant
US20120041285A1 (en) 2008-12-04 2012-02-16 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US8585627B2 (en) 2008-12-04 2013-11-19 The Invention Science Fund I, Llc Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure
EP2384168B1 (fr) 2008-12-04 2014-10-08 Searete LLC Implants de distribution d'excitation stérilisants à commande active
US20100215716A1 (en) * 2009-02-23 2010-08-26 Biomet Manufacturing Corp. Compositions and methods for coating orthopedic implants
US20100247600A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Therapeutic drug eluting implant cover and method of making the same
US9414864B2 (en) 2009-04-15 2016-08-16 Warsaw Orthopedic, Inc. Anterior spinal plate with preformed drug-eluting device affixed thereto
US9078712B2 (en) 2009-04-15 2015-07-14 Warsaw Orthopedic, Inc. Preformed drug-eluting device to be affixed to an anterior spinal plate
EP2475406B1 (fr) 2009-09-09 2015-10-21 Cook Medical Technologies LLC Procédés de fabrication de substrats chargés de médicament
US9012530B2 (en) * 2010-07-30 2015-04-21 Warsaw Orthopedic, Inc. Bioadhesive for periodontal gingival and/or bone tissues
EP3456200B1 (fr) 2011-05-10 2023-05-03 Next Science IP Holdings Pty Ltd Article ayant un solide antimicrobien et son utilisation
US20140248372A1 (en) 2011-09-19 2014-09-04 Emory University Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto
US9101678B2 (en) 2011-11-03 2015-08-11 Elwha Llc Heat-sanitization of surfaces
WO2013123507A1 (fr) * 2012-02-17 2013-08-22 Bacterin International, Inc. Composition et procédé de fabrication de revêtements polymères à viscosité réduite
EP2830672A1 (fr) * 2012-03-30 2015-02-04 Dentsply IH AB Dispositif médical présentant une surface comprenant un métal antimicrobien
US9956319B2 (en) 2012-05-31 2018-05-01 Baylor College Of Medicine Compositions useful as antibiofilm or antimicrobial agents and methods using same
CN104981219B (zh) 2013-01-08 2018-03-06 实践粉体技术有限公司 高强度注塑模制的矫形装置
US9693874B2 (en) 2013-03-15 2017-07-04 Blackstone Medical, Inc. Composite spinal interbody device and method
BR112015022965A2 (pt) 2013-03-15 2017-07-18 Laboratory Skin Care Inc composições de resveratrol em partículas finas secas e formuções tópicas incluindo as mesmas
EP2856946A1 (fr) * 2013-10-07 2015-04-08 Occlutech Holding AG Implant médical pour fermer une ouverture dans un corps et procédé de fabrication d'un tel implant médical
AU2015247588B2 (en) * 2014-04-16 2018-08-30 Biomet Manufacturing, Llc Methods for coating implant surfaces to treat surgical infections
CN104147642B (zh) * 2014-07-29 2016-07-20 复旦大学附属华山医院 抗感染人工韧带的制备方法
SE538635C2 (en) * 2014-09-15 2016-10-04 Observe Medical Aps Method for sterilizing a body fluid drainage system
US12350403B2 (en) * 2015-11-12 2025-07-08 The General Hospital Corporation Methods of making therapeutic polymeric material
AU2017211214A1 (en) 2016-01-25 2018-07-12 Smith & Nephew, Inc. Orthopaedic implant
WO2017179996A1 (fr) * 2016-04-11 2017-10-19 Aroa Biosurgery Limited Dispositif à base de collagène ayant des propriétés antifongiques
EP3664720A4 (fr) 2017-08-11 2021-05-12 Richard N. Terry Dispositif de ligature et procédé d'utilisation
CN109731137B (zh) * 2019-03-13 2021-05-07 陕西师范大学 具有生物抗污功能的白蛋白涂层的制备方法及具有生物抗污功能的材料
CN109821076B (zh) * 2019-03-13 2021-05-07 陕西师范大学 一种抗凝抗感染的多功能涂层的制备方法及抗凝抗感染的多功能材料

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705092A (en) * 1995-06-05 1998-01-06 Southwest Research Institute Multilayered biocidal film compositions
US5902283A (en) * 1995-04-24 1999-05-11 Baylor College Of Medicine Board Of Regents Antimicrobial impregnated catheters and other medical implants
US6054504A (en) * 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
US20030229401A1 (en) * 2001-07-10 2003-12-11 Baylor Method for treating medical devices using glycerol and an antimicrobial agent

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5115422B1 (fr) * 1970-10-31 1976-05-17
CS179567B1 (en) * 1974-11-25 1977-11-30 Vladimir Stoy Ionogennic hydrophilic in water insoluble gels based on partial saponificated polymers or copolymers acrylonitrile and method of preparing them
NL176004C (nl) * 1976-10-05 1985-02-01 Microbial Chem Res Found Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden.
US4306563A (en) * 1979-11-28 1981-12-22 Firma Pfrimmer & Co. Pharmazeutische Werke Erlangen Gmbh Catheter for introduction into body cavities
US4341768A (en) * 1981-04-03 1982-07-27 Bristol-Myers Company Antibiotic compounds
US4423153A (en) * 1981-12-03 1983-12-27 Board Of Regents, The University Of Texas System Methods and compositions for the detection and determination of cellular DNA
US4442133A (en) * 1982-02-22 1984-04-10 Greco Ralph S Antibiotic bonding of vascular prostheses and other implants
US4769013A (en) * 1982-09-13 1988-09-06 Hydromer, Inc. Bio-effecting medical material and device
US5197977A (en) * 1984-01-30 1993-03-30 Meadox Medicals, Inc. Drug delivery collagen-impregnated synthetic vascular graft
JPS61179162A (ja) 1984-09-19 1986-08-11 クリエートメディック株式会社 カテ−テル固定用膨張液
US4917686A (en) * 1985-12-16 1990-04-17 Colorado Biomedical, Inc. Antimicrobial device and method
US4895566A (en) * 1986-07-25 1990-01-23 C. R. Bard, Inc. Coating medical devices with cationic antibiotics
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5013306A (en) * 1989-01-18 1991-05-07 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5270358A (en) * 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
FR2679142B1 (fr) * 1991-07-18 1995-06-09 Nice Sophia Antipolis Universi Procede de protection des protheses, des materiaux implantables provisoires ou definitifs contre la colonisation et l'infection bacterienne.
US5217493A (en) * 1992-03-11 1993-06-08 Board Of Regents, The University Of Texas System Antibacterial coated medical implants
US5591224A (en) * 1992-03-19 1997-01-07 Medtronic, Inc. Bioelastomeric stent
US5357636A (en) * 1992-06-30 1994-10-25 Dresdner Jr Karl P Flexible protective medical gloves and methods for their use
US5507777A (en) * 1994-10-07 1996-04-16 United States Surgical Corporation Method and apparatus for treating a portion of a suture and forming a suture tip for attachment to a needle
US5756145A (en) * 1995-11-08 1998-05-26 Baylor College Of Medicine Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor
US6558686B1 (en) * 1995-11-08 2003-05-06 Baylor College Of Medicine Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor
US5830539A (en) * 1995-11-17 1998-11-03 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods for functionalizing and coating substrates and devices made according to the methods
JP2000513209A (ja) * 1996-02-16 2000-10-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗微生物ペプチドと使用方法
US6172163B1 (en) * 1996-09-02 2001-01-09 Dimitry Rein Ultra-high molecular weight polyolefin fiber composite matrix, and process for the manufacture thereof
DE19727554A1 (de) * 1997-06-28 1999-01-07 Huels Chemische Werke Ag Verfahren zur Hydrophilierung der Oberfläche polymerer Substrate mit einem Makroinitiator als Primer
US5939208A (en) * 1997-11-07 1999-08-17 Biomimetics, Inc. Method for creation of biomimetic surfaces
US6166007A (en) * 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
ATE399565T1 (de) * 1998-07-07 2008-07-15 Transdermal Technologies Inc Zusammensetzungen für die schnelle und nicht- irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung
US6156373A (en) * 1999-05-03 2000-12-05 Scimed Life Systems, Inc. Medical device coating methods and devices
AU5168200A (en) 1999-05-28 2000-12-18 Minimed, Inc. Medication device with polymeric surface coating protecting against protein adhesion
ATE419880T1 (de) * 2000-06-09 2009-01-15 Baylor College Medicine Kombination von antimikrobiellen wirkstoffen und bakterieller interferenz zum überziehen medizinischer vorrichtungen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902283A (en) * 1995-04-24 1999-05-11 Baylor College Of Medicine Board Of Regents Antimicrobial impregnated catheters and other medical implants
US5705092A (en) * 1995-06-05 1998-01-06 Southwest Research Institute Multilayered biocidal film compositions
US6054504A (en) * 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
US20030229401A1 (en) * 2001-07-10 2003-12-11 Baylor Method for treating medical devices using glycerol and an antimicrobial agent

Also Published As

Publication number Publication date
WO2005096990A2 (fr) 2005-10-20
AU2005231417A1 (en) 2005-10-20
US7238363B2 (en) 2007-07-03
US20050271694A1 (en) 2005-12-08
EP1737378A2 (fr) 2007-01-03
CA2561496A1 (fr) 2005-10-20

Similar Documents

Publication Publication Date Title
WO2005096990A3 (fr) Nouvelle modification de protheses medicales
EP3248600B8 (fr) Combinaisons et modes d'administration d'agents thérapeutiques et thérapie combinée
WO2004021968A3 (fr) Solution destinee a une application ungueale et peri-ungueale
WO2005027993A3 (fr) Preservation d'acces vasculaire chez des patients en hemodialyse
WO2006013441A3 (fr) Utilisation de bacteries probiotiques dans la preparation de compositions topiques destinees a la protection de la peau
WO2006053007A3 (fr) Revetement d'aiguille antimicrobien pour perfusion prolongee
WO2005037323A3 (fr) Methode pour inhiber une signalisation de nf-kappa b et son utilisation pour traiter et pour prevenir des maladies humaines
WO2007002572A3 (fr) Nattokinase pour reduire la viscosite du sang total
WO2007146426A3 (fr) Nanobilles pour délivrance de médicament
AU2003300200A1 (en) Valve treatment catheter and methods
WO2006113802A3 (fr) Dispositif pour l'administration de stimulation par electrodes des muscles dorsaux et abdominaux
EP1891991A3 (fr) Procédé de contrôle d'élution d'un agent thérapeutique
DE602006020070D1 (de) Verringerung von schwindel, einer nebenwirkung im zusammenhang mit einer pirfenidon-therapie
WO2005102392A3 (fr) Methodes de traitement d'une infection a vih
WO2006086693A3 (fr) Dispositifs medicaux
WO2007134203A3 (fr) Traitements anticancéreux
WO2006138571A3 (fr) Composition et procede d'inhibition, de prevention ou d'amelioration des complications associees a l'ingestion d'une substance ou d'un agent medicinal, chimique ou biologique
WO2007130501A3 (fr) Polythérapie pour traiter le cancer
WO2006034001A3 (fr) Procedes de traitement de l'infection par vih
WO2005094554A3 (fr) Agents, methodes et traitements therapeutiques
WO2005042699A3 (fr) Polypeptides modifies presentant une activite therapeutique et leurs methodes d'utilisation
WO2007009895A3 (fr) Utilisation d'equivalents du facteur viia ou viia pour prevenir ou attenuer le developpement hemorragique et/ou le developpement d'oedeme suite a une hemorragie intracerebrale chez les patients traites en therapie antiplaquettaire
WO2003007876A3 (fr) Conjugues acide amine-acide gras normal et utilisations therapeutiques
WO2006094064A3 (fr) Methode de diminution de cicatrices a l'aide de vitamine d
WO2007077454A3 (fr) Composition therapeutique

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2005231417

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2561496

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

ENP Entry into the national phase

Ref document number: 2005231417

Country of ref document: AU

Date of ref document: 20050331

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2005231417

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2005731606

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2005731606

Country of ref document: EP