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WO2005092426A1 - Cathéter - Google Patents

Cathéter Download PDF

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Publication number
WO2005092426A1
WO2005092426A1 PCT/JP2005/004762 JP2005004762W WO2005092426A1 WO 2005092426 A1 WO2005092426 A1 WO 2005092426A1 JP 2005004762 W JP2005004762 W JP 2005004762W WO 2005092426 A1 WO2005092426 A1 WO 2005092426A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
tubular body
sealing member
sealing
adapter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2005/004762
Other languages
English (en)
Japanese (ja)
Inventor
Hitoshi Tahara
Kohei Fukaya
Masato Hashiba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2004091580A external-priority patent/JP2005270527A/ja
Priority claimed from JP2004213809A external-priority patent/JP4669675B2/ja
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of WO2005092426A1 publication Critical patent/WO2005092426A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A61M25/10184—Means for controlling or monitoring inflation or deflation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less

Definitions

  • the present invention relates to a catheter having a balloon that is introduced percutaneously transluminally into a body and expands or closes a lumen in the body, and a catheter system including an adapter that operates the catheter.
  • angioplasty performed to improve the blood flow on the peripheral side of the blood vessel by expanding the stenotic or occluded part of the blood vessel.
  • Transluminal Angioplasty ⁇ PTCA Percutaneous Transluminal Coronary Angioplasty etc.
  • stents for maintaining the state of an expanded stenosis have been widely used in recent years.
  • Balloon catheters used for PTA and PTCA are mainly used as a set of a guide catheter and a guide wire to expand a stenosis site or an occlusion site of a blood vessel.
  • a guide catheter is first inserted from the femoral artery, the distal end is positioned at the entrance of the coronary artery via the aorta, and then a guide wire penetrated through the balloon catheter is inserted into the blood vessel.
  • Advance over the stenosis or occlusion then advance the balloon catheter over the guidewire to inflate the balloon while positioned at the stenosis or occlusion to expand the stenosis or occlusion.
  • the procedure is followed, and the balloon is deflated and removed from the body.
  • This balloon catheter is useful not only for treating stenotic or occluded sites in blood vessels but also for many medical applications including insertion into blood vessels and into various body cavities and tubular tissues.
  • the thrombus may be released from the inner wall of the blood vessel and occlude a peripheral blood vessel on the downstream side.
  • the lesion contains many plaque-like plaques.
  • plaque may be scattered from the lesion due to dilatation with a balloon catheter, and may block peripheral blood vessels.
  • a vasodilator may be administered to restore blood flow, or a drug such as a thrombolytic agent may be locally administered to dissolve obstructions. It takes time, there is a problem. If peripheral obstruction is severe and hemodynamics are poor, auxiliary measures such as IABP are also used.
  • a temporary occlusion nore catheter has been used as a means for temporarily obstructing a blood vessel.
  • the shaft of the temporary occlusion balloon catheter is used as a guide wire, and another therapeutic catheter, for example, a vasodilation balloon catheter, travels along the shaft of the temporary occlusion balloon catheter. It is inserted up to the lesion. Thereafter, a temporary occlusion drain catheter is dilated at the periphery of the lesion, and the lesion is treated while the blood flow is blocked.
  • the shaft of the balloon catheter for temporary occlusion may be located inside the guide wire lumen of another treatment catheter, and is generally thinner than the inner diameter of the guide wire lumen over the entire length of the shaft.
  • the temporary occlusion balloon is inflated by an inflation device connected to the proximal end of the catheter.
  • a seal portion is provided at the proximal end of the catheter so that the nolane can be expanded even when the dilatation device is removed, and the outer diameter of the seal portion is smaller than that of the guide wire lumen of the treatment catheter. It must be thin.
  • Patent Document 1 As the sealing portion of such a balloon catheter for temporary occlusion, an outer diameter smaller than 0.014 inch, which is the outer diameter of the most common guide wire used in ordinary PTCA or the like, is described.
  • the invention discloses a catheter valve having a very small cross section.
  • a fluid-tight seal is formed between the surface of a tubular body of a catheter and the surface of a seal portion present inside or outside thereof. Control the flow.
  • the surfaces form a liquid-tight seal as described above, it is not possible to easily operate the seal portion where the frictional resistance between the surface of the tubular body and the surface of the seal portion is large. For this reason, there is a risk that the extended part that extends the seal force during operation may be damaged.
  • such a valve having a liquid-tight seal between its surfaces needs to be manufactured with extremely tight tolerances, which poses a problem in the manufacturing process.
  • Patent Document 2 discloses a system for maintaining the inflation of a temporary occlusion balloon.
  • the expansion member is inserted at the proximal end of the inflation conduit for inflating the balloon to maintain the inflation of the balloon.
  • the surface of the inner surface and the outer surface of the extension member are connected or screwed together.
  • problems such as high frictional resistance as in Patent Document 1.
  • it is necessary to tighten the screws between thin members to form a seal.
  • Patent Document 3 discloses a catheter that blocks blood flow using a single inflation balloon and an adapter for inflating or deflating the inflation balloon.
  • the adapter in the prior art is detachable from the proximal end portion of the catheter, and the adapter is also provided with the function of operating the elongate member (movable part in the present invention) in the prior art.
  • the extension member is directly operated by the operator's hand, but it is considerably difficult to directly operate the thin shaft by hand.
  • the fitting between the extension member and the catheter body and the fluid seal are performed by threading or friction.In the case of threading, inserting a thin extension member into a thin shaft with a screw in a real clinical setting is very operation. There is a problem that a smooth procedure cannot be performed.
  • Patent Document 4 discloses a catheter having a valve of a rope opening file and an inflation adapter for operating the valve.
  • the adapter in the prior art is a housing having a first portion and a second portion, which secures the catheter within the housing, and the first and second portions are brought together and housed with a lock'clip.
  • the catheter cannot be easily fixed by one operation, and there is a problem that a smooth operation cannot be performed in an actual clinical site.
  • an external pressurized fluid source the inflation mechanism in the present invention
  • the prior art adapter is configured so that the movement distance of the valve increases with an increase in the operation amount of the actuator (the operation part in the present invention), and furthermore, the distance between the panel for fixing the catheter and the catheter is increased. Since the valve is configured to maximize frictional force, if the valve setting is misaligned, the valve will not move anymore. There was a problem of doing it. A similar problem is caused by the valve striking structure. In such cases, if the moving distance of the knob is small, the fluid cannot be sealed, and if the moving distance of the valve is large, the catheter will be broken.
  • Patent Document 1 Japanese Patent Publication No. 2000-511082
  • Patent Document 2 JP 2001-190686 A
  • Patent Document 3 JP 2002-126093 A
  • Patent Document 4 Japanese Translation of PCT International Publication No. 2001-523535
  • the sealing member can be operated with a small force and can be easily manufactured without requiring strict tolerances in the manufacturing process.
  • Another object of the present invention is to provide an adapter that enables stable operation.
  • the present invention provides a catheter having a balloon, a tubular body having an inflation lumen through which a fluid for expanding or deflating the balloon is movable, and a fluid seal portion for sealing the fluid.
  • a catheter characterized in that the structure of the sealing portion comprises a movable sealing member having a tapered portion whose outer diameter gradually decreases, and a sealing portion force fitted to the tapered portion. It is preferable that a maximum outer diameter of the tapering portion of the sealing member is larger than a minimum inner diameter of the sealing portion. According to such a configuration, the sealing member can be operated with a small force without using a specific expansion adapter, and can be easily manufactured without requiring strict tolerances in a manufacturing process.
  • the center line average roughness Ra of the sealed portion is 0.80 m or less, more preferably, the center line average roughness Ra of the sealed portion is 0.40 / zm or less. And more preferably, the center line average roughness Ra of the sealed portion is 0.20 / zm or less. According to these configurations, it is easy to exhibit high sealing properties. [0016] It is preferable to have a structure for preventing the sealing member from falling off from the proximal end of the tubular body.
  • a substance for improving the sealing property is disposed at a contact portion between the sealing member and the sealing portion, and a seal is provided at a contact portion between the sealing member and the sealing portion. More preferably, the substance for improving the properties is silicone oil.
  • the fluid seal portion exists on the proximal side of a maximum outer diameter portion of the sealing member.
  • one fluid seal portion is present on each of a distal side and a proximal side of a maximum outer diameter portion of the sealing member. According to these structures, it becomes possible to prevent the sealing member, which does not have a special drop-prevention mechanism, from falling off the proximal end force of the tubular body.
  • the fluid seal portion is present at one position on the distal side and one position on the proximal side of the maximum outer diameter portion of the sealing portion, respectively, when the seal on the distal side is released, This makes it possible to prevent the fluid from flowing out of the tubular body from the opening at the proximal end of the tubular body.
  • a fluid passage for expanding or deflating the balloon passes through a side surface of the tubular body closer to the sealing portion than the sealing portion. According to this structure, it is possible to reliably secure a fluid path.
  • the present invention is also a force catheter system including a catheter and an adapter for operating the catheter, wherein the catheter is capable of moving a balloon and a fluid for expanding or deflating the balloon.
  • a tubular body having an inflation lumen; and a catheter having a fluid seal portion for sealing the fluid, wherein the structure of the fluid seal portion is a movable sealing member having a tapered portion whose outer diameter gradually decreases.
  • a sealing portion force fitted with the tapered portion, wherein the adapter is adapted to insert a movable or detachable movable portion including the proximal portion of the catheter including the sealing portion and the sealing member.
  • a control mechanism be provided that has an operating portion that does not generate a load equal to or more than a predetermined value in the axial direction of the movable portion when the operating portion is operated. According to such a configuration, the catheter can be fixed easily and securely, and does not cause breakage of the catheter, and a stable operation can be performed without depending on the skill of the operator or operation error.
  • the control mechanism since the control mechanism includes an elastic body, the control mechanism can be easily realized.
  • the operation portion which preferably includes an inflation mechanism for injecting a fluid into the medical device from the vicinity of the movable portion, is operated by rotation. According to these configurations, it is possible to make the device itself compact, which does not require a large space for the procedure table.
  • the port portion of the medical device be sealed and sealed by fixing the proximal portion of the medical device at the fixing portion. According to these configurations, smooth and reliable operation of the force catheter at the clinical site is possible.
  • the catheter of the present invention has a fluid seal portion inside a tubular body having an inflation lumen of the catheter, and has a movable portion having a tapered portion whose outer diameter gradually decreases as a result of the structural force of the fluid seal portion. Since the sealing member and the sealing part force that fits into the tapered portion are also configured, the sealing member can be operated with a small force, and it can be easily performed without requiring tight tolerances in the manufacturing process. It is possible to provide a catheter that can be manufactured.
  • the present invention relates to a catheter having a balloon, a tubular body having an inflation lumen through which a fluid for expanding or deflating the balloon is movable, and a fluid seal portion for sealing the fluid, wherein the structure of the fluid seal portion is provided.
  • a catheter comprising: a movable sealing member; and a sealing partial force fitted to the tapered portion. More preferably, the maximum outer diameter of the tapered portion of the sealing member is larger than the minimum inner diameter of the sealing portion.
  • the present invention relates to various catheters having a balloon, for example, PTCA catheters, PTA catheters, balloon catheters for temporary occlusion, and the like.
  • FIG. 1 shows an overall view of a balloon catheter for temporary occlusion which is one embodiment of the catheter according to the present invention.
  • the left side shows the proximal side and the right side shows the far side.
  • 2 (a) and 2 (b) are enlarged views (cross-sectional views) of the vicinity of the proximal end of the catheter including the fluid seal portion in one embodiment of the catheter according to the present invention.
  • One embodiment of the catheter according to the present invention, shown in FIG. 1, has an elongated, flexible tubular body 101 and a balloon 102 at the distal end of the catheter for expanding or occluding a body lumen. .
  • FIGS. 2A and 2B show an inflation lumen 201 in which a fluid for expanding or contracting a balloon formed inside a tubular body 205 is movable, and a fluid sealing portion 202.
  • the sealing member 204 is in close contact with the tapered portion 203A where the outer diameter is reduced due to the force on the proximal side of the sealing member 203 whose fluid sealing portion is movable toward the distal side.
  • the maximum outer diameter (the outer diameter at 203B) of the tapered portion 203A be larger than the minimum inner diameter of the sealing portion 204.
  • the sealing member 203 has a tapered portion 203A, and the outer diameter force of the tapered portion 203A at 203B is larger than the minimum inner diameter of the sealing portion 204. be able to. Further, since the taper portion 203A is provided, an appropriate seal can be formed by the amount of the sealing member 203 pushed into the sealing portion 204. Therefore, if the outer diameter of 203B is smaller than the inner diameter of the tubular body 205 which is larger than the minimum inner diameter of the sealed portion 204, no particularly tight tolerance is required. . Therefore, the sealing member 203 can be easily manufactured.
  • a sealing member having no tapered portion should form a seal with the inner surface of the sealing portion 204 as in the prior art disclosed in JP-A-2001-190686.
  • a strict tolerance is required for the outer diameter of the sealing member, and it cannot be easily manufactured.
  • the sealing member since a seal is formed between the inner surface of the sealing portion 204 and the outer surface of the sealing member, the sealing member may be damaged during an operation in which the fitting is tight.
  • the catheter according to the present invention forms a seal by fitting the tapered portion 203A and the sealing portion 204, so that the formation and release of the seal can be performed with a small force.
  • the elevation angle ⁇ of the tapered portion 203A is preferably 0.10 degrees or more, and more preferably 0.40 degrees or more. If the elevation angle ⁇ is less than 0.10 degrees, the tight contact between the tapered portion 203A and the sealing portion 204 is so strong that the sealing member 203 may be damaged during operation.
  • the elevation angle ⁇ of the tapered portion 203A is preferably not more than 60.00 degrees.
  • the proximal portion 203C of the sealing member 203 is necessarily formed of a tapered portion and a cylindrical portion, and need not necessarily be formed of only a tapered portion or a cylindrical portion. Such a shape is also possible.
  • the distal portion 203D of the sealing member can be cylindrical or any other shape.
  • the most important portion of the sealing member 203 is the tapered portion 203A, and the shapes of 203C and 203D can be any shape.
  • FIG. 2 (a) shows a state in which a seal is formed in the fluid seal portion 202, and in this state, the movement of fluid between the outside of the tubular body 205 and the inflation lumen 201. Is impossible.
  • FIG. 2B shows a state in which the seal is released at the fluid seal portion 202.In this state, the fluid can move between the outside of the tubular body 205 and the inflation lumen 201, and the balloon 102 expands. And shrinkage can be performed.
  • the proximal opening force of the tubular body 205 can also inflate and deflate the balloon 102 by injecting fluid. Further, it is preferable to have a side hole on the tubular body through which a fluid for expanding or deflating the balloon passes.
  • the center line average roughness Ra on the surface of the sealed portion 204 is preferably 0.80 m or less.
  • the center line average roughness Ra on the surface of the sealed portion 204 is greater than 0.80 m.
  • high sealing performance cannot be achieved, and the sealing member 203 needs to be pressed with a large force against the sealing portion 204, so that the sealing member 203 may be damaged.
  • the seal may be released, or fluid may leak out of the tubular body 205 from a gap in the seal.
  • the center line average roughness Ra is preferably 0.40 / zm or less, and more preferably the center line average roughness. Ra is less than 0.20 / zm.
  • the center line average roughness Ra and ⁇ o IS ⁇ 0601-1982.
  • the measuring device for example, there is a three-dimensional interference measuring microscope (manufactured by zygo).
  • the sealing portion 204 can be made of any material. In order to exhibit high sealing performance in the fluid sealing portion 202, it is preferable that the sealing portion 204 also has a high polymer material force. Considering the easiness of production, it is more preferable that the group force is selected from the group consisting of polyimide, polyamide, polyurethane, Teflon (registered trademark), silicone rubber, polyamide-based elastomer and polyurethane-based elastomer. ,. In order to achieve high sealing performance when the thickness of the sealed portion 204 is thin and when repeated sealing operations are performed, polyimide is also used in view of ease of tube formation and resin hardness. Is more preferable. When the sealing portion 204 is made of metal, the above-mentioned surface roughness is particularly important.
  • a substance that improves the sealing property is arranged at the contact portion between the sealing member 203 and the sealing portion 204.
  • the substance that improves the sealability is silicone oil in consideration of the fluidity.
  • the material of the sealing portion 204 can be freely selected regardless of the material of the tubular body 205.
  • the sealing portion 204 can be joined to the inside of the tubular body 205 by a method known to those skilled in the art (for example, adhesion or welding)
  • the sealing member 203 has a certain degree of rigidity and is easy to operate, at least a part thereof, for example, 203A and 203C is made of stainless steel, Ni—Ti, Ni—Ti Fe, Ni— Ti—Cu, Ni—Ti—Cr, Ni—Ti—V, Ni—Ti—Co, Ni—Ti—Nb, Ni—Ti—Pd, Ni—Ti—Cu—Cr, Fe Mn—Si, Co— It is preferable that one or more selected from the group force composed of Cr or a composite thereof is also formed.
  • the sealing member 203 in order to exhibit high sealing performance in the fluid seal portion 202, considering the ease of manufacture when manufacturing a catheter in which at least a part of the sealing member 203 preferably has a high polymer material strength, Polyimide, polyamide, polyurethane, Teflon (registered trademark), silicone rubber, polyamide-based elastomer or polyurethane-based elastomer are preferred.
  • the sealing portion 204 when the sealing portion 204 is made of metal, it is preferable that at least a portion of the sealing member 203 involved in the adhesion with the sealing portion 204 also has the above-mentioned polymer material strength.
  • FIGS. 3 (a) and 3 (b) are cross-sectional views showing the vicinity of the proximal end of the catheter in another embodiment.
  • the inflation lumen 301 and the sealing member 303 It has sealing components 304A, 304B, and tubular bodies 305, 305A, 305B.
  • the sealing portion 304A in 03 (a) is a part of the tubular body 305, and the sealing member 303 includes a tapered portion 303A, a proximal portion 303C, and a distal portion 303D.
  • the sealing portion 304B in FIG. 3 (b) is a part of the tubular body 305A, and is disposed inside the tubular body 305B. Since the sealing portion is a part of the tubular body, the number of constituent members is reduced, and the manufacturing is easy.
  • FIG. 4 is a cross-sectional view near the proximal end of the catheter according to another embodiment, and includes an inflation lumen 401, a sealing member 403, and a sealing portion 404, similarly to the embodiment of FIG.
  • the tubular body force at the proximal end portion of the catheter may be constituted by tubular bodies 405A, 405B, and 405C, or may be made of different materials.
  • the tubular body is used as a very small diameter catheter such as a balloon catheter for temporary occlusion, the thickness of the tubular body needs to be extremely thin, so that the kink resistance and the delivery property of the catheter are important.
  • stainless steel Ni—Ti, Ni—Ti Fe, Ni—Ti—Cu, Ni—Ti—Cr, Ni—Ti—V, Ni—Ti—Co, Ni—Ti—Nb, Ni—Ti—Pd , Ni—Ti—Cu—Cr, Fe Mn Si, and Co—Cr It is preferable to be made of one or more selected from or a composite thereof.
  • the respective tubular joints 406A and 406B can be joined by methods well known to those skilled in the art (eg, gluing or welding). Joining multiple tubular bodies Thus, such a structure near the proximal end of the catheter can be easily manufactured.
  • a side hole 407 on the tubular body through which a fluid for expanding or contracting the nore passes.
  • the sealing member 403 When the sealing member 403 is moved proximally to release the seal and expand or contract the balloon, only the proximal end opening 408 of the tubular body and the outside of the tubular body 405A-405B and the inflation lumen 401 are used.
  • the fluid When the fluid is moved between the balloon and the balloon, it may take time to inflate or deflate the balloon, which narrows the passage of the fluid.
  • the time required to inflate or deflate the balloon is also associated with the time required for the entire procedure, and may increase the burden on the patient.
  • the side hole 407 be provided to ensure the path of the fluid.
  • the location of the side hole 407 may be any location as long as it is on the tubular body proximal to the sealing portion 404, and the number and shape of the side holes are not limited.
  • the sealing member 403 By having a structure to prevent the sealing member 403 from falling off from the proximal end opening 408 of the tubular body, when the seal is once released and the seal is to be formed again, the sealing member is lost or damaged. Can be prevented. Further, in the case of a balloon catheter for temporary occlusion, it is difficult to reconnect the sealing member that has fallen off from the proximal end cap of the tubular body and the outer diameter of the sealing member to be reduced at the treatment site. It will be. Therefore, it is preferable to have a structure that prevents the sealing member 403 from falling off from the proximal end opening 408 of the tubular body.
  • a method of fixing a portion of the sealing member 403 to the tubular body is considered, but the maximum outer diameter of a portion of the sealing member 403 that can be inserted into the tubular body is considered. Is preferably larger than the minimum inner diameter at the proximal end 409 of the tubular body, so that the sealing member 403 is prevented from falling off to prevent the sealing member 403 from falling off. In order to have such a structure for preventing the sealing member from falling off, it is preferable that the sealing portion is disposed inside the tubular body.
  • the method of manufacturing the proximal end 409 of the tubular body is not limited, as shown in FIG.
  • the proximal end portion of the tubular body 405C constituting the proximal end is subjected to drawing processing to form the proximal end of the tubular body. 409 to It can be easily manufactured, and the strength of the proximal end 409 of the tubular body can be increased. It is also possible to adopt a structure in which another member is joined to the proximal end of the tubular body to prevent the sealing member from falling off from the proximal end of the tubular body. For example, by joining a member having a ring portion having an inner diameter smaller than the maximum outer diameter portion of the sealing member to the proximal end of the tubular body, it is possible to provide a mechanism for preventing the sealing member from falling off. Such a mechanism for preventing the sealing member from falling off can be applied to any embodiment.
  • FIG. 5 is a cross-sectional view near the proximal end of the catheter according to still another embodiment.
  • the inflation lumen 501, the sealing member 503, the sealing portion 504, and the side hole 507 are provided. It has.
  • the portion near the proximal end of the catheter is formed by the tubular body 505A and the tubular body 505B.
  • the proximal end portion of the tubular body 505A is drawn, covered with the tubular body 505B, and formed at the joint 506 by a method well known to those skilled in the art. Bonding at a distance makes it possible to reduce the profile near the catheter proximal end.
  • the tubular body 505B is drawn at the proximal end to prevent the sealing member 503 from falling off.
  • the method of preventing the sealing member 503 from falling off is not limited to this, and a tubular body having an inner diameter smaller than the outer diameter of the tubular body 503B may be joined to the proximal end portion of the tubular body 505B.
  • the reinforcing member 510 to the proximal end portion of the sealing member 503 at the joint 511 by a method known to those skilled in the art, the operation of the sealing member 503 becomes easy.
  • the tubular body 505B or the tubular body 510 always exists outside the proximal cylindrical portion 503C of the sealing member 503, the strength of the catheter can be increased.
  • the sealing member 503 and the reinforcing member 510 can be integrally formed. Such a structure of the reinforcing member or the like can be applied to any embodiment.
  • FIG. 6 is a cross-sectional view near the proximal end of a catheter according to yet another embodiment, which is the same as the embodiment shown in FIG. 5 except for the sealing portion 604 and the panel 612.
  • the sealing portion 604 is a portion obtained by drawing the proximal end portion of the tubular body 605A.
  • the sealing portion 604 is joined to the tubular body 605B at the joining portion 606, and at the same time, a seal is formed by being in close contact with the sealing member 603. are doing.
  • the panel 612 disposed between the largest outer diameter portion 603B that can be inserted into the inside of the tubular body of the sealing member 603 and the proximal end drawing portion of the tubular body 605B releases the seal once, and re-opens the seal.
  • the seal can be formed by the force of the panel 612 without applying a force toward the distal end to the sealing member 603 from outside.
  • the spring 612 may or may not be joined to the sealing member 603 and the tubular body 605B. When joining, it is joined by a method well known to those skilled in the art. Further, the position where the panel 612 is arranged is not limited to the above-mentioned portion, and may be any other position that may be arranged outside the tubular body 605B or inside the reinforcing member 610. Such panels can be used in any embodiment.
  • FIGS. 7 and 8 are cross-sectional views of a catheter proximal end according to still another embodiment, in which a fluid seal portion 702 is present on a proximal side of a maximum outer diameter portion 703B of a sealing member 703.
  • the fluid seal portions 802A and 802B may be located one each on the distal side and the proximal side of the largest outer diameter portion 803B of the sealing portion 803. Since the fluid seal portion is located on the proximal side of the maximum outer diameter portion of the sealing member, it is necessary to prevent the sealing member from falling off the proximal end force of the tubular body without providing a special drop-out prevention mechanism. Becomes possible.
  • the fluid seal portion is present at one position on the distal side and one position on the proximal side of the largest outer diameter portion of the sealing portion, a proximal seal is formed when the distal seal is released. It is possible to prevent a fluid other than the side hole 807 from flowing out of the tubular body.
  • the tubular body 101 of the temporary occlusion balloon catheter as shown in Fig. 1 may be located inside the guide wire lumen of another therapeutic force table.
  • the temporary occlusion balloon catheter is expanded by a dilatation device connected to the proximal end of the catheter or to the normal expansion port, but when the dilatation device is connected, another treatment catheter can be temporarily occluded by the balloon. Unable to operate along the tubular body 101 of the catheter.
  • the force catheter according to the present invention has a fluid seal portion 202 and can be used as such a temporary occlusion balloon catheter because the balloon can be maintained in an inflated state even when the inflation device is removed. preferable.
  • the type of the treatment catheter that can be used as the outer diameter of the tubular body 101 and the portion 103 near the proximal end of the catheter is smaller is used.
  • the outer diameter of the tubular body 101 and the portion 103 near the proximal end of the catheter should be less than 0.018 inches. More preferably, it is 0.014 inches or less, which is the most common guide wire outer diameter that is preferred.
  • the temporary occlusion balloon catheter may have a guidewire lumen, and the guidewire lumen may be located anywhere on the catheter.
  • FIG. 10 is a plan view and FIG. 11 is a side view of an embodiment of the included adapter.
  • the adapters 100 1 and 1101 according to the present invention shown in FIGS. 10 and 11 have grooves 1002 and 1102 for inserting a catheter, a fixing portion 1003, a driving portion 1004, a fixing knob 1005, and an abutting portion 1006.
  • FIG. 12 shows a balloon catheter for temporary occlusion used as one embodiment of the catheter.
  • FIG. 12 (a) is an external view of a balloon catheter for temporary occlusion
  • the temporary occlusion balloon catheter 1201 includes a tubular body 1202, a nolan 1203, an inflation lumen 1204 through which a fluid for expanding or deflating the balloon 1203 can move, a port portion 1205 through which fluid flows to the side surface of the proximal portion, It has a movable portion 1206 including a sealing member movable relative to the tubular body 1202, and a fluid seal portion 1207 for sealing a fluid by a sealing portion 1208 fitted with the movable portion 1206.
  • the catheter 1201 After introducing the catheter 1201 into the patient and placing the force catheter so that the balloon 1203 comes to the periphery of the lesion, insert the proximal portion of the catheter 1201 into the groove 1002 of the adapter 1001 and rotate the fixation knob 1005. With this, the catheter 1201 can be fixed to the adapter 1001. At this time, it is preferable to fix the catheter 1201 by dropping it into the groove 1002 to determine the circumferential position of the catheter 1201. The proximal end of the catheter 1201 is abutted against the abutting portion 1006, which is preferable.
  • the axial position of the catheter 1201 can be easily and reliably determined. For example, if a lateral hole for positioning is provided in the adapter and the lateral hole is positioned in the circumferential direction through a catheter, The proximal end force of a thin catheter must also be passed through the side hole. In an actual clinical setting, it is necessary to check the position of the lateral force lateral hole in order to pass the catheter through the lateral hole even further in the dark, which is extremely troublesome.
  • the catheter may be kinked when the catheter is passed through the side hole.
  • the catheter 1201 When the catheter 1201 is positioned in the circumferential direction by a structure in which the catheter 1201 is dropped into the groove 1002 as in the adapter 1001 according to the present invention, the operator can surely drop the catheter 1201 into the adapter 1001 even in the dark clinical setting where the upper force is also dropped.
  • the catheter 1201 is not likely to be broken by kink or the like.
  • it when positioning the catheter in the axial direction by arranging a marker on the catheter at a specified position on the adapter, it is very difficult in an actual dark clinical site, but it is very difficult as in the case of the adapter 1001 according to the present invention.
  • the positioning can be performed reliably and easily even in a dark clinical site.
  • the fixing knob 1005 is rotated to fix the catheter 1201
  • the fixing of the movable portion 1206 of the catheter 1201 in the driving portion 1004 and the fixing of the proximal portion of the catheter 1201 in the fixing portion 1003 are performed almost simultaneously.
  • the operation by rotation of the fixing knob 1005 communicates with both the driving portion 1004 and the fixed portion 1003.
  • FIG. 13 shows an inner view of the adapter of the embodiment shown in FIG. FIG. 13 (a) is a view of the adapter 1301 before fixing the force table
  • FIG. 13 (b) is fixing the catheter, expanding the balloon, and closing the fluid seal portion of the catheter.
  • It is a diagram of the adapter 1301.
  • the inflation knob 1308 is then rotated to inject fluid into the balloon 1203, and the Can be extended.
  • the inflation knob 1308 is preferably capable of finely controlling the amount of injection into the balloon 1203.
  • the adapter 1301 since the adapter 1301 has an injection volume scale, the operator can easily control the injection volume.
  • the adapter 1301 Since the adapter 1301 has the inflation mechanism as described above, it is possible to reduce the size of the device itself, which does not require a large space on the procedure table.
  • the sealing portion 1307 of the adapter 1301 is preferably made of silicone rubber or butadiene rubber.
  • the proximal side of the catheter 1201 and the movable part 1206 are fixed to the adapter 1301, and at the same time, the sealing part 1307 sandwiches the port 1205 of the catheter 1201 and securely seals around the port 1205. And a reliable operation becomes possible.
  • FIG. 14 shows an enlarged view of the fixed part and the drive part of the adapter of the embodiment shown in FIG. Fig.
  • Fig. 14 (b) shows the state of the fixed part and the drive part after the operation to close the fluid seal part of the catheter described later is performed. is there.
  • the driving portion 1404 moves to the distal side of the catheter 1201 via the shaft 1401. Since the movable part 1206 of the catheter 1201 is fixed by the drive part 1404, the movable part 1206 also moves to the distal side with the movement of the drive part 1404, and the catheter moves by moving the movable part 1206 to the distal side.
  • the fluid seal portion existing on the proximal side of 1201 can be closed.
  • the sealing portion of the drive portion 1404 (the portion in contact with the movable portion 1206 of the drive portion 1404) 1407 is preferably made of a polymer material.
  • the polymer material is preferably polyamide, polyurethane, polyester, polyolefin, Teflon ( (Registered trademark), silicone rubber, butadiene rubber, polycarbonate, ABS resin, polypropylene, polystyrene, polyamide-based elastomer, polyesterenole-based elastomer, polyolefin-based elastomer or polyurethane-based elastomer or a composite thereof.
  • the polyamide-based elastomer be used.
  • the operation performed in operation part 1309 The shaft for transmitting and the driving portion 1404 are preferably connected by an elastic body, and more preferably the elastic body is a panel. Since the shaft 1401 and the driving portion 1404 are connected in the moving direction of the shaft 1401 by the panel 1405 and the panel 1406, the load in the moving direction of the shaft 1401 due to the operation of the operating portion 1309 is absorbed by the panel 1405 and the panel 1406. Through the portion 1404, it is possible to have a control mechanism in which a load equal to or more than a certain value is not generated in the movable portion 1206 in the axial direction.
  • the load generated in the axial direction of the movable part 1206 can be easily determined by the spring constant, and the most suitable panel can be selected according to the catheter to be used.
  • Panel 1405 and panel 1406 may or may not be joined to shaft 1401 and drive portion 1404. When joining, joining is performed by a method well known to those skilled in the art.
  • the load in the direction of movement of the shaft 1401 is moved by the panel 1405 when moving the movable part 1206 to the distal side, and by the panel 1406 when moving it to the proximal side. Can be absorbed.
  • the axial load generated on the movable part 1206 can be reduced when moving the distal side and when moving proximally. It can be adjusted with.
  • the fluid seal portion 1207 of the catheter 1201 shown in FIG. 12 is closed by pressing the distal side of the movable portion 1206 against the sealed portion 1208 inside the tubular body 1202, but the movable distance of the movable portion 1206 is too large. In such a case, the sealed portion 1208 or the movable portion 1206 may be broken.
  • the fixing of the catheter 1201, the inflation, and the operation of the operating portion 1309 are preferably operated by rotation.
  • FIG. 15 shows another embodiment of the fixed part and the drive part of the adapter included in the catheter system according to the present invention.
  • FIG. 15 (a) shows a state before the catheter is fixed
  • FIG. 15 (b) shows a state of the fixed part and the driving part after an operation of closing a fluid seal part of the catheter described later is performed.
  • FIG. 16 shows a balloon catheter for temporary occlusion as another embodiment of the catheter.
  • a temporary occlusion balloon catheter 1601 in this embodiment includes a tubular body 1602 having a distal end and a proximal end, a balloon 1603 near the distal end, and a balloon 1603 expanded or deflated between the distal and proximal ends.
  • FIG. 16A is an external view of the fluid seal portion 1607 of this embodiment in a closed state
  • FIG. 16B is an inner view of the fluid seal portion 1607 in an open state.
  • the catheter 1601 is introduced into the patient, and the catheter 1601 is arranged so that the balloon 1603 comes to the periphery of the lesion.Then, the proximal side of the catheter 1601 is inserted into the groove 1502, and the shaft 1501 is moved in the circumferential direction of the catheter 1601. Then fix the catheter 1601. At this time, the fixing of the movable portion 1606 of the catheter 1601 in the driving portion 1504 is preferably performed via a panel 1505 existing between the shaft 1501 and the driving portion 1504. This allows the panel 1505 to absorb the load in the driving portion 1504 in the circumferential direction of the catheter 1601 and to keep the load fixing the catheter 1601 constant.
  • the drive portion 1504 is moved to move the movable portion 1606 of the catheter 1601 to the distal side, and the fluid seal portion 1607 of the catheter 1601 is closed.
  • the load for fixing the movable portion 1606 constant, it is possible to have a control mechanism in which a load equal to or greater than a certain value is generated in the axial direction of the movable portion 1606 through the drive portion 1504.
  • the load in the axial direction of the drive part 1504 is absorbed by sliding between the contact part 1508 of the drive part 1504 (the part in contact with the movable part of the drive part) 1508 and the movable part 1606, and a certain amount or more in the axial direction of the movable part 1606 It is possible to avoid the occurrence of the load.
  • the load to fix the movable part 1606 is determined by the frictional force between the contact part 1508 and the movable part 1606, the panel constant of the panel 1505 and the force using the material of the contact part 1508 can be selected according to the catheter. , Realizes the optimal load for fixing the movable part 1606 It is possible to do.
  • FIG. 3 a catheter including the embodiment of FIG. 3 (a), an adapter including the embodiment of FIG. 5, and a balloon catheter for temporary occlusion shown in the embodiment of FIG.
  • FIG. 5 The shape of the comparative example is shown in FIG.
  • the present invention relates to a catheter system including a catheter having a balloon and an adapter for operating the catheter.
  • a fluid seal portion without installing a balloon at the distal end was used.
  • all evaluations were performed (Evaluation 1).
  • the total length for evaluating the fluid seal portion and balloon portion was 100 mm, which was not used for a temporary occlusion balloon catheter having a length of 1800 mm or more used in an actual clinical site.
  • the evaluation of the catheter system was performed using a balloon catheter for evaluation of degree (Evaluation 2).
  • a stainless steel (SUS316L) metal tube with an outer diameter of 0.31 mm and an inner diameter of 0.23 mm was used as the tubular body through which the fluid could move.
  • a tube with a total length of 110 mm was cut into 100 mm.
  • One end of the metal tube cut to 100 mm was a proximal end, and the other end was a distal end.
  • the residue of the tubular body was used to measure the center line average roughness Ra.
  • the remainder of the tubular body that is, the remaining 10 mm metal tube obtained by cutting the tubular body is polished until it becomes semicircular, and the center line average roughness Ra of the inner surface of the metal tube is measured with a three-dimensional interference measurement microscope (manufactured by zygo). Was measured.
  • the center line average roughness Ra was 0.89 m.
  • the shape of the sealing member shall be the shape shown in 303 shown in Fig. 3 (a), and the outer diameter at the proximal portion 303C of the sealing member is 0.30mm, the length is 40mm, and the distal portion of the sealing member is 30 3D outer diameter 0.10mm, length 30mm, taper section 303A length 20mm It was designed to be.
  • the material of the sealing member was stainless steel (SUS304).
  • the outer diameter of the 43mm part of the 303D side end force is calculated to be 0.23mm.
  • the outer diameter of the actually obtained sealing member was measured using a laser outer diameter measuring device and found to be 0.22 mm-0.24 mm. That is, there was a difference of ⁇ 0. Olmm between the calculated value and the actually measured value. Of these, the evaluation described later was performed using a sealing member having an outer diameter of 0.22 mm at the portion where the 303D side end force was also 43 mm.
  • a tubular body was produced in the same manner as in Example 1.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.89 m.
  • the evaluation described below was performed using a sealing member having an outer diameter of 0.23 mm at a portion where the end force at the 303D side was 43 mm among those obtained in Example 1.
  • a tubular body was produced in the same manner as in Example 1.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.89 m.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.24 mm at a portion where the 303D side end force was 43 mm among the sealing members obtained in Example 1.
  • a tubular body was prepared in the same manner as in Example 1, except that a metal tube having a different center line average roughness was used.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.62 m.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.22 mm at a portion where the end force on the 303D side was 43 mm among the sealing members obtained in Example 1.
  • a tubular body was prepared in the same manner as in Example 4.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.62 m.
  • the evaluation described below was performed using a sealing member having an outer diameter of 0.23 mm at a portion where the end force at the 303D side was 43 mm among those obtained in Example 1.
  • a tubular body was prepared in the same manner as in Example 4.
  • the center line average roughness of the inner surface of the metal tube is R a was 0.62 / zm.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.24 mm at a portion where the 303D side end force was 43 mm among the sealing members obtained in Example 1.
  • a tubular body was prepared in the same manner as in Example 1, except that a metal tube having a different center line average roughness was used.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.28 m.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.22 mm at a portion where the end force on the 303D side was 43 mm among the sealing members obtained in Example 1.
  • a tubular body was produced in the same manner as in Example 7.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.28 / zm.
  • the evaluation described below was performed using a sealing member having an outer diameter of 0.23 mm at a portion where the end force at the 303D side was 43 mm among those obtained in Example 1.
  • a tubular body was produced in the same manner as in Example 7.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.28 / zm.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.24 mm at a portion where the 303D side end force was 43 mm among the sealing members obtained in Example 1.
  • a tubular body was prepared in the same manner as in Example 1, except that a metal tube having a different center line average roughness was used.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.13 m.
  • the evaluation described later was performed using a sealing member having an outer diameter of 0.22 mm at a portion where the end force on the 303D side was 43 mm among the sealing members obtained in Example 1.
  • Example 12 A tubular body was produced in the same manner as in Example 10.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.13 m.
  • the sealing member obtained in Example 1 was evaluated using a sealing member having an outer diameter of 0.23 mm at a portion where the end force on the 3D side was also 43 mm, which was described later. (Example 12)
  • a tubular body was produced in the same manner as in Example 10.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.13 m.
  • an evaluation described later was carried out using a sealing member having an outer diameter of 0.24 mm at a portion where the end force on the 3D side was 43 mm among those obtained in Example 1.
  • a stainless steel (SU S316L) metal tube having an outer diameter of 0.33 mm and an inner diameter of 0.25 mm was used.
  • a metal tube with a total length of 100 mm was used, with one end being the proximal end and the other being the distal end.
  • a tube of 0.80mm in outer diameter, 0.38mm in inner diameter, and 30mm in length is sealed by heat-sealing the distal end and near the distal end.
  • a side hole having a major axis of about 1.5 mm and a minor axis of about 0.5 mm was opened using a razor and used as a sleeve.
  • the proximal end side of the sleeve was placed 5 mm over the distal end side of the tubular body, and bonded using a two-component urethane adhesive.
  • a tube with a diameter of 1.20 mm, an inner diameter of 1.00 mm, and a length of 15 mm was used as the balloon, and the center of the balloon was placed over the side hole of the sleeve.
  • Adhesion was performed using a two-component urethane adhesive, 5 mm on each side.
  • the movable part has the shape shown in 1606 in Fig.
  • the outer diameter at the distal part of the movable part is 0.10 mm
  • the length is 20 mm
  • the outer diameter at the proximal part of the movable part is 0.30 mm
  • the length Using a stainless steel (SUS304) tapered wire having a length of 30 mm and a length of the intermediate tapered portion of 20 mm 20 balloon catheters for evaluation of this example were produced.
  • the two-component urethane adhesive used was Nippon Polyurethane Industry Co., Ltd., 4235 and Coronate 4403, mixed at a ratio of 2: 1 to obtain an adhesive.
  • the center part of the adapter was joined to produce an adapter for evaluation.
  • the axial movement distance of the driving part was 6 mm.
  • Adhesive part is Atochem polyamide ela Stoma Pebax4033 sheets were used.
  • a silicone tube with an outer diameter of 5 mm and an inner diameter of 3 mm was inserted into the fluid injection hole leading to the sealed part, and an lmL syringe for balloon expansion was connected to the opposite end.
  • the panel used was a panel constant INZmm.
  • a tubular body was produced in the same manner as in Example 1.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.89 m.
  • the sealing member is a stainless steel (SUS304) stepped without tapered portion shown in Fig. 9 and has an outer diameter of 0.30mm, a length of 40mm, and a proximal portion 903C of the sealing member.
  • the outer diameter of the sealed portion 903E was 0.21 mm and the length was 40 mm.
  • a tubular body was prepared in the same manner as in Example 1, except that a metal tube having a different center line average roughness was used.
  • the center line average roughness Ra of the inner surface of the metal tube was 0.13 m.
  • the sealing member is a stainless steel (SUS304) with a step that does not have a tapered portion as shown in Fig. 9 and has an outer diameter of 0.30 mm, a length of 4 Omm at the proximal portion 903C of the sealing member, and a length of 4 Omm.
  • the outer diameter of the sealed part 903E was 0.21 mm and the length was 40 mm.
  • a sealing member was inserted at the proximal end of the tubular body, and a connector was connected at the distal end.
  • a three-way stopcock was connected to the connector, a pressure gauge was connected to one of them, and an inflation device filled with water was connected to the other. With a pressure of 5 atm applied by an inflation device, the sealing member is pushed into the proximal end of the tubular body to a position where the sealing member can be pushed in so that the sealing member is not broken, and a fluid seal is formed. I left it. The degree of pressure retention was evaluated 10 minutes later than immediately after the application of pressure. Table 1 shows the results.
  • the pressure holding ratio is a value obtained by dividing the value of the pressure gauge after 10 minutes by the value of the pressure gauge immediately after applying pressure and multiplying by 100. The closer the value is to 100%, the higher the sealing performance is It indicates that. The operability indicates the ease of pushing the sealing member into the tubular body and the state at the time of sealing.
  • the pressure from the inflation device which has a large gap with the sealing member, causes the sealing member to fall off from the tubular body, so that the sealing performance could not be exerted.
  • the pressure retention rate was 83%, which was a sufficient force to exhibit high sealing performance.
  • the outer diameter was 0.23 mm as in Comparative Examples 3 and 6, there was no gap between the tubular body and the sealing member, and the sealing member that had extremely high resistance when the sealing member was pushed into the tubular body was damaged. . As a result, it was not possible to evaluate the sealing performance.
  • the proximal side of the balloon catheter for evaluation was inserted into the groove of the adapter for evaluation, and the port portion was arranged so as to be inside the sealed portion.
  • the movable part was removed 3 mm from the position where it was inserted until it hit the port.
  • the catheter was fixed, and 0.15 mL of water was also injected into the syringe for balloon expansion, thereby expanding the norain.
  • the shaft was operated by hand until the drive part stopped moving in the axial direction.
  • the catheter was removed from the adapter, and the state of the balloon 3 minutes later was evaluated. After that, the catheter was fixed to the adapter again, and the shaft was manually operated to move the driving portion to the opposite side until the power was removed, and the movable portion was also removed from the port portion. Further, the same operation was repeated once again, and a second evaluation was performed. Table 1 shows the results.
  • Example 13 in Example 13, both the first time and the second time The balloon was maintained inflated three minutes after the adapter force was removed, and no catheter was able to remove the movable part from the port.
  • Comparative Example 7 in the first evaluation, only 11 catheters maintained balloon expansion three minutes after the catheter was removed from the adapter. For the remaining nine tubes, the fluid seal was broken and the balloon could not be maintained inflated. In addition, nine of the nine fluid seals were destroyed and three of the eleven with the expansion maintained, a total of twelve that could not remove the port force from the movable part. In the case of the sample in which the fluid seal part was broken, both the tubular body and the movable part kinked, and a force that could not be removed was applied.
  • FIG. 1 is a schematic view of one embodiment of a catheter according to the present invention.
  • FIG. 2 is a schematic view showing a state where a seal is formed near a proximal end of the catheter according to an embodiment of the catheter according to the present invention (a), and a schematic view showing a state where the seal is released. (B).
  • FIGS. 3A and 3B are schematic views (a) and (b) of a catheter according to another embodiment of the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 4 is a schematic view of a catheter according to another embodiment of the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 5 is a schematic view of a catheter according to another embodiment of the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 6 is a schematic view of another embodiment of the catheter according to the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 7 shows a catheter according to another embodiment of the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 8 is a schematic view of a catheter according to another embodiment of the present invention in the vicinity of the proximal end of the catheter.
  • FIG. 9 is an explanatory drawing of a comparative example.
  • FIG. 10 is a schematic view of an embodiment of the adapter according to the present invention.
  • FIG. 11 is a schematic side view of an embodiment of the adapter according to the present invention.
  • FIG. 13 is schematic diagrams (a) and (b) of another embodiment of the adapter according to the present invention.
  • Figures 14 (a) and 14 (b) are central schematic views of an embodiment of the adapter according to the present invention.
  • FIGS. 15A and 15B are schematic diagrams (a) and (b) of central parts of another embodiment of the adapter according to the present invention.
  • FIG. 16 is schematic views (a) and (b) of another embodiment of the medical device using the adapter according to the present invention.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Sont fournis un cathéter avec lequel on peut manipuler un élément de scellement avec peu de force et qui peut être facilement produit sans exiger de tolérance stricte dans les processus de production ainsi qu'un adaptateur permettant une manipulation stable du cathéter. Un cathéter ayant un ballon, un corps tubulaire (205) avec une lumière d'inflation (201) et une section de scellement du liquide (202) pour sceller le liquide, dans laquelle la structure de la section de scellement du liquide est constituée d'un membre de scellement hermétique amovible (203) ayant une section pointue (203A) dont le diamètre extérieur se réduit graduellement et d'une section de scellement hermétique (204) fixée sur la section pointue. Est fourni un système de cathéter pour faire fonctionner le cathéter.
PCT/JP2005/004762 2004-03-26 2005-03-17 Cathéter Ceased WO2005092426A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004-091580 2004-03-26
JP2004091580A JP2005270527A (ja) 2004-03-26 2004-03-26 カテーテル
JP2004213809A JP4669675B2 (ja) 2004-07-22 2004-07-22 アダプタ
JP2004-213809 2004-07-22

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WO2005092426A1 true WO2005092426A1 (fr) 2005-10-06

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Cited By (3)

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WO2007080843A1 (fr) * 2006-01-11 2007-07-19 Kaneka Corporation Systeme catheter
EP2478929A1 (fr) * 2011-01-25 2012-07-25 Karl Storz GmbH & Co. KG Cathéter à ballonnet doté d'une tige métallique
USD798448S1 (en) 2015-03-17 2017-09-26 Karl Storz Gmbh & Co. Kg Sialendoscope

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US4813934A (en) * 1987-08-07 1989-03-21 Target Therapeutics Valved catheter device and method
US4848344A (en) * 1987-11-13 1989-07-18 Cook, Inc. Balloon guide
US5207229A (en) * 1989-12-21 1993-05-04 Advanced Biomedical Devices, Inc. Flexibility steerable guidewire with inflatable balloon
US6017323A (en) * 1997-04-08 2000-01-25 Target Therapeutics, Inc. Balloon catheter with distal infusion section
US6090083A (en) * 1996-01-31 2000-07-18 Scimed Life Systems, Inc. Low profile valve and balloon catheter
JP2000511082A (ja) * 1996-05-20 2000-08-29 パークサージ，インコーポレイテッド 小断面カテーテルバルブ
JP2001523535A (ja) * 1997-11-20 2001-11-27 パークサージ インコーポレイテッド ロー・プロファイル・カテーテル・バルブおよびインフレーション・アダプタ

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US4813934A (en) * 1987-08-07 1989-03-21 Target Therapeutics Valved catheter device and method
US4813934B1 (fr) * 1987-08-07 1992-05-12 Target Therapeutics Inc
US4848344A (en) * 1987-11-13 1989-07-18 Cook, Inc. Balloon guide
US5207229A (en) * 1989-12-21 1993-05-04 Advanced Biomedical Devices, Inc. Flexibility steerable guidewire with inflatable balloon
US6090083A (en) * 1996-01-31 2000-07-18 Scimed Life Systems, Inc. Low profile valve and balloon catheter
JP2000511082A (ja) * 1996-05-20 2000-08-29 パークサージ，インコーポレイテッド 小断面カテーテルバルブ
US6017323A (en) * 1997-04-08 2000-01-25 Target Therapeutics, Inc. Balloon catheter with distal infusion section
JP2001523535A (ja) * 1997-11-20 2001-11-27 パークサージ インコーポレイテッド ロー・プロファイル・カテーテル・バルブおよびインフレーション・アダプタ

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007080843A1 (fr) * 2006-01-11 2007-07-19 Kaneka Corporation Systeme catheter
JP5067164B2 (ja) * 2006-01-11 2012-11-07 株式会社カネカ カテーテルシステム
EP2478929A1 (fr) * 2011-01-25 2012-07-25 Karl Storz GmbH & Co. KG Cathéter à ballonnet doté d'une tige métallique
US8715228B2 (en) 2011-01-25 2014-05-06 Karl Storz Gmbh & Co. Kg Balloon catheter with metal shaft
USD798448S1 (en) 2015-03-17 2017-09-26 Karl Storz Gmbh & Co. Kg Sialendoscope

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