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WO2005077046A3 - Composition et procede pour le traitement de la mastite - Google Patents

Composition et procede pour le traitement de la mastite Download PDF

Info

Publication number
WO2005077046A3
WO2005077046A3 PCT/US2005/004048 US2005004048W WO2005077046A3 WO 2005077046 A3 WO2005077046 A3 WO 2005077046A3 US 2005004048 W US2005004048 W US 2005004048W WO 2005077046 A3 WO2005077046 A3 WO 2005077046A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
treating mastitis
lytic
specific
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/004048
Other languages
English (en)
Other versions
WO2005077046A2 (fr
Inventor
Lawrence Loomis
Vincent Fischetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Publication of WO2005077046A2 publication Critical patent/WO2005077046A2/fr
Anticipated expiration legal-status Critical
Priority to US11/510,805 priority Critical patent/US20070077235A1/en
Publication of WO2005077046A3 publication Critical patent/WO2005077046A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017Lysozyme (3.2.1.17)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne une composition et un procédé pour le traitement de la mastite, ce traitement consistant à utiliser une quantité efficace d'au moins un agent lytique spécifique de la bactérie provoquant la maladie. L'enzyme lytique est génétiquement codée par un bactériophage qui peut être spécifique de ladite bactérie. Cette enzyme peut être au moins une protéine ou des peptides lytiques sous forme naturelle ou modifiée.
PCT/US2005/004048 2004-01-16 2005-02-10 Composition et procede pour le traitement de la mastite Ceased WO2005077046A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/510,805 US20070077235A1 (en) 2004-01-16 2006-08-14 Composition and method of treating mastitis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54365104P 2004-02-12 2004-02-12
US60/543,651 2004-02-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/510,805 Continuation US20070077235A1 (en) 2004-01-16 2006-08-14 Composition and method of treating mastitis

Publications (2)

Publication Number Publication Date
WO2005077046A2 WO2005077046A2 (fr) 2005-08-25
WO2005077046A3 true WO2005077046A3 (fr) 2009-03-26

Family

ID=34860445

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/004048 Ceased WO2005077046A2 (fr) 2004-01-16 2005-02-10 Composition et procede pour le traitement de la mastite

Country Status (1)

Country Link
WO (1) WO2005077046A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007106951A1 (fr) 2006-03-23 2007-09-27 Agriculture Victoria Services Pty Limited Protéine antimicrobienne
AU2007298511B2 (en) * 2006-07-10 2013-03-21 Advanced Enzyme Technologies Limited Compositions for prevention and treatment of mastitis and metritis
US8956628B2 (en) 2007-12-13 2015-02-17 Zoetis Products Llc Bacteriophage preparations and method of use thereof
US20110209228A1 (en) * 2008-03-13 2011-08-25 Benjamin Cocks Method of treatment using antimicrobial composition
CN116640755B (zh) * 2023-07-21 2023-10-20 临沂大学 一种链球菌前噬菌体裂解酶lys1519及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858962A (en) * 1987-05-11 1999-01-12 Ambi Inc. Composition for treating mastitis and other staphylococcal infections
US6238661B1 (en) * 1997-10-31 2001-05-29 New Horizons Diagnostics Corp. Use of bacterial phage associated lysing enzymes for treating various illnesses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858962A (en) * 1987-05-11 1999-01-12 Ambi Inc. Composition for treating mastitis and other staphylococcal infections
US6238661B1 (en) * 1997-10-31 2001-05-29 New Horizons Diagnostics Corp. Use of bacterial phage associated lysing enzymes for treating various illnesses

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KERR ET AL.: "Mammary expression of new genes to combat mastitis.", J ANIM SCI., vol. 81, no. 3, 2003, pages 38 - 47 *
LOEFFLER ET AL.: "Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase.", SCIENCE., vol. 294, no. 5549, 7 December 2001 (2001-12-07), pages 2170 - 2172, XP002392510, DOI: doi:10.1126/science.1066869 *

Also Published As

Publication number Publication date
WO2005077046A2 (fr) 2005-08-25

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