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WO2005072650A1 - Catheter de pose d'endoprothese - Google Patents

Catheter de pose d'endoprothese Download PDF

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Publication number
WO2005072650A1
WO2005072650A1 PCT/US2005/000150 US2005000150W WO2005072650A1 WO 2005072650 A1 WO2005072650 A1 WO 2005072650A1 US 2005000150 W US2005000150 W US 2005000150W WO 2005072650 A1 WO2005072650 A1 WO 2005072650A1
Authority
WO
WIPO (PCT)
Prior art keywords
self
stent delivery
delivery assembly
tapered tip
expanding stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/000150
Other languages
English (en)
Inventor
William S. Henry
John E. Ortiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Boston Scientific Scimed Inc
Original Assignee
Boston Scientific Ltd Barbados
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados, Scimed Life Systems Inc filed Critical Boston Scientific Ltd Barbados
Priority to MXPA06011748A priority Critical patent/MXPA06011748A/es
Priority to JP2006551106A priority patent/JP4857125B2/ja
Priority to CA002553529A priority patent/CA2553529A1/fr
Priority to EP05704976A priority patent/EP1706065A1/fr
Publication of WO2005072650A1 publication Critical patent/WO2005072650A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/97—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve the outer sleeve being splittable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod

Definitions

  • the present invention is related generally to medical devices. More specifically, the present invention is related to catheters.
  • the present invention includes stent delivery catheter apparatus with a tapered tip that is fracturable during deployment of a self-expanding stent that has been loaded onto the catheter.
  • Atherosclerotic disease is a leading cause of death in the industrialized world, particularly in the United States.
  • Many heart attacks and strokes are caused in part by a narrowed, stenosed blood vessel.
  • a medical procedure commonly used to deal with vessel stenosis is angioplasty.
  • Angioplasty in particular Percutaneous Transluminal Angioplasty (PTA)
  • PTA Percutaneous Transluminal Angioplasty
  • the balloon can then be inflated to widen or dilate the narrowed region.
  • the balloon catheter can then be withdrawn.
  • the widened vessel rebounds or re-closes, narrowing the vessel over a period of time.
  • Stents have come into increasing use to prevent the widened vessel regions from narrowing after angioplasty.
  • a stent typically having a tubular shape, can be put in place in the widened vessel region to hold the vessel walls apart and the lumen open in the event the conditions would otherwise result in re-stenosis.
  • One class of stents requires that the stent be forcibly outwardly expanded to put the stent into position against the vessel walls.
  • Another class of stents, self-expanding stents can be delivered to a site in a compressed or constrained configuration and released in the vessel region to be supported.
  • the self-expanding stent then expands in place to a configuration having a wide lumen, typically pressing firmly against the vessel walls where released.
  • the stent is commonly placed at a recently dilated, stenosed vessel region.
  • Self-expanding stents can be delivered to a target site mounted over an inner tube or shaft and constrained within the distal end of an enclosing retractable tube or sleeve.
  • the self-expanding stent can be freed from the restraint of the outer sheath by either distally pushing the inner shaft against the stent or proximally pulling the retractable outer sheath from over the stent.
  • the self- expanding stent can expand to force itself against the vessel inner walls.
  • Self- expanding stents are often elastically biased to assume an original larger shape after being temporarily compressed into a smaller size to more easily be transported through blood vessels to the target site.
  • catheters that deliver self-expanding stents There is an ongoing need for improvements in catheters that deliver self-expanding stents.
  • a self-expanding stent delivery assembly includes a shaft having a proximal end, a distal end, a distal region, a lumen, and a longitudinal axis.
  • a retractable sheath having an outer surface, a proximal end and a distal end is co- axially disposed around the shaft distal region.
  • a stent is disposed co-axially between the shaft and the retractable sheath.
  • a tubular tapered tip is bonded to the retractable sheath distal end.
  • the tubular tapered tip has an elongate region predisposed to fracturing.
  • a method of delivering a self-expanding stent includes placing a stent delivery device at a target site.
  • the stent delivery device includes a shaft having a proximal end, a distal end, a distal region, a lumen, and a longitudinal axis; a retractable sheath having a proximal end and a distal end co-axially disposed around the shaft distal region; a stent disposed co-axially between the shaft and the retractable sheath; and a tubular tapered tip bonded to the retractable sheath distal end, the tubular tapered tip having an elongate region predisposed to fracturing.
  • the stent is deployed at the target site by retracting the retractable sheath or advancing the stent and fracturing the elongate region predisposed to fracturing.
  • FIG. 1 is a partial longitudinal cross-sectional view of a stent delivery device
  • FIG. 2 is a cross-sectional view of the stent delivery device of FIG. 1 taken along line 2-2
  • FIG. 3 is a perspective view of a tapered tip
  • FIG. 4 is a perspective view of the tapered tip of FIG. 3 while partially deploying a stent
  • FIG. 5 is a perspective view of another embodiment of a tapered tip; and FIG. 6 is a perspective view of the tapered tip of FIG. 5 while partially deploying a stent.
  • the invention is amenable to various modifications and alternative forms, specifics thereof have been shown by way of example in the drawings and will be described in detail. It should be understood, however, that the intention is not to limit the invention to the particular embodiments described. On the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention.
  • stent delivery device and method for using the stent delivery device of the present invention are believed to be applicable to a variety of applications where delivery of stents is desired, for example, atherosclerotic stent delivery. While the present invention is not so limited, an appreciation of various aspects of the invention will be gained through a discussion of the examples provided below.
  • the recitation of numerical ranges by endpoints includes all numbers subsumed within that range (e.g., 1 to 5 includes 1 , 1.5, 2, 2.75, 3, 3.80, 4, and 5).
  • the singular forms "a”, “an”, and “the” include plural referents unless the content clearly dictates otherwise.
  • FIG. 1 illustrates a stent delivery device or catheter 30.
  • Catheter assembly 30 includes an inner tube 32 having a lumen 33 therethrough (as shown in Figure 2), a distal region 40 and a distal end 42.
  • Inner tube 32 is preferably formed of a metal, polymeric material, or polymeric/metal composite material suitable for delivering a stent through tortuous vessel passages and in one embodiment, is suitable for receiving a guidewire therethrough.
  • One useful material can include a braided polyamide tubing.
  • the catheter assembly 30 can be guided to the target site via a guidewire 80.
  • the guidewire 80 can be within the inner tube 32 lumen 33.
  • the guide wire can be any operable diameter such as, for example, 0.01 to 0.04 inch or 0.014 to 0.035 inch, however a guide wire is not required in all embodiments.
  • a retractable sheath 34 having a distal region or end 44 is slidably disposed over inner tube 32, having an annular space 66 sufficient in size to receive a compressed stent between inner tube 32 and retractable sheath 34.
  • the retractable sheath 34 can remain static, and a stent or inner tube 32 can be advancable relative to the retractable sheath 34.
  • Retractable sheath 34 can be formed of a metal, polymeric material, or polymeric/metal composite material preferably sufficiently lubricious to ease in advancing catheter assembly 30 through increasingly smaller blood vessels.
  • Sheath 34 can be formed from a variety of materials such as, for example, high density polyethylene, nylon, reinforced nylons, or polyurethanes. Sheath 34 can have an inner layer 31 including a lubricious material such as, for example, polytetrafluoroethylene.
  • a stop 35 is affixed to the inner tube 32 proximal of its distal end 42, about the length of a stent 50 and near the distal end of the catheter 30. The stop 35 functions to hold the stent 50 axially during deployment of the stent 50 relative to the outer tube 34.
  • a distally positioned tapered tip 36 is disposed distal to or adjacent to the inner tube distal region 40 and is affixed to or formed integral with retractable sheath 34.
  • tapered tip 36 can be formed of a shrinkable film material, for example, a heat-shrinkable material such as polyolefin copolymer, nylon, or polytetrafluoroethylene.
  • tapered tip 36 can be formed of the same or similar material to the material forming the retractable sheath 34.
  • the tapered tip 36 can be formed from the same layer of material forming at least a portion of the retractable sheath 34.
  • the tapered tip 36 can be secured to retractable sheath 34 using a variety of methods such as, for example, molding, extrusion, heat bonding, adhesives, laser bonding, or solvent welding, using methods well known to those skilled in the art.
  • Any type of connection means may be used to affix the tapered tip 36 to the retractable sheath 34.
  • This connection means can include, for example, a lap joint, butt joint or integral molding.
  • a mechanical connection such as threads or friction fit could be utilized.
  • the tapered tip 36 can include a waist portion 64 and a free portion 60.
  • the tapered tip 36 is formed integrally with retractable sheath 34 and the outer surface of the tapered tip 36 is continuous with the outer surface of the retractable sleeve 34, thus the connection is smooth and substantially free of transitions.
  • Tapered tip 36 is illustrated having an open distal end 70.
  • the tapered tip 36 can have a closed distal end 70.
  • the open distal end 70 can be sized and configured to slidably engage or pass the guide wire 80.
  • a guide wire 80 is not required in all embodiments.
  • the waist portion 64 can be disposed to and affixed to the distal end 44 of the retractable sheath 34.
  • the free portion 60 can extend distally beyond the distal end 44 of the retractable sheath 34.
  • the tapered tip 36 can aid in tracking stent delivery device 30 through vessel passages and turns.
  • the tapered tip 36 is conically tapered.
  • the tapered tip 36 can have an arcuate taper or any arrangement of constant diameters and tapers, as desired.
  • the tubular tip 36 has at least one elongate region predisposed to fracturing 90.
  • the tubular tip 36 can have 2, 3, 4, 5, 6, 7, 8, 9, 10 or more elongate regions predisposed to fracturing 90.
  • the elongate region predisposed to fracturing 90 fractures the tapered tip to expand the open distal end 70 and allows the stent 50 to pass through the fractured tapered tip 36 open distal end 70 generally unimpeded.
  • the elongate region predisposed to fracturing 90 can be co-planar with a longitudinal axis running along the length of the stent delivery device 30.
  • the elongate region predisposed to fracturing 90 can be formed on the tapered tip 36 before the tapered tip 36 is affixed to the retractable sheath 34, or formed during the process of affixing the tapered tip 36 to the retractable sheath 34 or integrally forming the tapered tip 36 from the layer of material forming at least a portion of the retractable sheath 34, or after affixing/integrally forming the tapered tip 36 with the retractable sheath 34.
  • the elongate region predisposed to fracturing 90 can be a line of perforations that extend through a portion of or through the entire tubular tip 36 wall thickness.
  • the elongate region predisposed to fracturing 90 can be a score line that extends through a portion of the tubular tip 36 wall thickness where the wall thickness along the score line 90 is less than the thickness along the remaining tubular tip 36 wall.
  • the elongate region predisposed to fracturing 90 can be material having a tensile strength that is less than the tensile strength of the remaining tubular tip 36.
  • FIG. 2 is a cross-sectional view of the stent delivery device of FIG. 1 taken along line 2-2.
  • An inner lumen 33 is coaxially disposed about a guidewire 80.
  • a self- expanding stent 50 can be placed into annular space 66 between retractable sheath 34 and inner tube 32.
  • the stent 50 can be placed over the inner tube 32 by sliding the stent 50 proximally over the inner tube distal end 42.
  • Stent 50 can be compressed using a suitable tool or jig, to decrease the outer diameter of the stent 50 to a size compatible with the annular space 66.
  • the stent 50 With the stent 50 compressed, the stent 50 can be axially and proximally slid over inner tube 32 and within sleeve distal region 44, to reside in annular space 66.
  • any restraining tool or jig can be removed from the catheter.
  • tubular tip 36 With stent 50 in position, tubular tip 36 can be affixed to retractable sheath 34 distal end 44.
  • a compressed stent 50 can be placed onto the inner tube 32 and loaded into the catheter 30 from a proximal end of the catheter 30. The inner tube 32 and compressed stent 50 can be moved toward the sleeve distal region 44. The tubular tip 36 can be attached to the retractable sheath 34 prior to loading the compressed stent 50 into the catheter 30.
  • the retractable sheath 34 can be any material as described above such as, for example, a clear medical grade PTFE (polytetrafluoroethylene) extrusion which covers the distal 2-20 cm (depending on stent length) of the stent delivery device 30.
  • the retractable sheath 34 could be made of any suitable material as described above.
  • a specific alternative embodiment could utilize a fluoropolymer material which is transparent to visible light to enable the operator to directly view deployment in an endoscopic delivery procedure. Such materials are well known in the art.
  • retractable sheath 34 can be connected to a proximal retraction handle (not shown) by a stainless steel pull-wire.
  • the proximal end of retractable sheath 34 slidably seals to elongate shaft 20, permitting it to slide proximally along elongate shaft when retracted by pull-wire.
  • the stent delivery system can include a rapid exchange guide wire system.
  • the stent 50 can be compressed at low temperature for loading into delivery system 30 and held in its reduced delivery configuration by retractable sheath 34.
  • the original stent shape can be restored as the nitinol stent self-expands, exerting radial force on the constricted portion of the body lumen to re-establish patency.
  • a stent delivery catheter showing the retraction handle is described in U.S. Patent No. 6,391,051, which is incorporated by reference herein.
  • FIG. 3 is a perspective view of a tapered tip 36 prior to deploying a stent 50.
  • a tubular tip 36 can be affixed to the distal end 44 of the retractable sheath 34.
  • the tubular tip 36 includes a waist portion 64 and a tapered portion 60.
  • the waist portion 64 is shown integrally bonded to or integrally formed with the distal region or end 44 of the retractable sheath 34 providing a continuous and/or smooth outer surface across the tubular tip 36 and retractable sheath 34.
  • the tubular tip 36 has an open distal end 70 with an inner diameter that is less than the inner diameter of the waist portion 64 and is sized and configured to engage a guidewire 80, but this is not required in all embodiments.
  • FIG. 4 is a perspective view of the tapered tip of FIG. 3 while partially deploying a stent 50.
  • the retractable sheath 34 is moved toward the elongate shaft 20 in the direction D, the elongate region predisposed to fracturing 90 fractures and the tapered tip 36 expands to allow the stent 50 to expand away from the inner tube 32 and onto the target site.
  • the stent 50 fractures the tapered tip 36 as the stent 50 passes through the tapered tip 36 substantially unencumbered.
  • FIG. 5 is a perspective view of another tapered tip 136 prior to deploying a stent 150.
  • a tubular tip 136 can be affixed to the distal region or end 144 of the retractable sheath 134.
  • the tubular tip 136 includes a waist portion 164 and a tapered free portion 160.
  • the waist portion 164 can be bonded to the distal end 144 of the retractable sheath 134.
  • the tubular tip 136 has a closed distal end 171 with an inner diameter that is less than the inner diameter of the waist portion 164.
  • the tubular tip 136 has at least two elongate regions 190 predisposed to fracturing as described above.
  • FIG. 6 is a perspective view of the tapered tip of FIG. 5 while partially deploying a stent 150.
  • the retractable sheath 134 As the retractable sheath 134 is moved toward the elongate shaft in the direction D, the elongate regions predisposed to fracturing 190, fractures and the tapered tip 136 expands to allow the stent 150 to expand away from the inner tube 132 and onto the target site.
  • the stent 150 fractures the tapered tip 136 as the stent 150 passes through the tapered tip 136 substantially unencumbered.
  • the stent 150 may be deployed by advancing the inner tube 132 or stent 150 through the tapered tip 136 in an opposite direction to direction D.
  • the stent 150 fractures the tapered tip 136 as the stent 150 passes through the tapered tip 136 substantially unencumbered.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne un ensemble de pose d'endoprothèse auto-dilatable comprenant une tige présentant une extrémité proximale, une extrémité distale, une zone distale, une lumière, et un axe longitudinal. Une gaine rétractable présentant une surface extérieure, une extrémité proximale et une extrémité distale est disposée de manière coaxiale autour de la zone distale de la tige. Une endoprothèse est disposée de manière coaxiale entre la tige et la gaine rétractable. Une pointe effilée tubulaire est fixée sur l'extrémité distale de la gaine rétractable. La pointe effilée tubulaire présente une zone allongée prédisposée à la cassure.
PCT/US2005/000150 2004-01-23 2005-01-05 Catheter de pose d'endoprothese Ceased WO2005072650A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
MXPA06011748A MXPA06011748A (es) 2005-01-05 2005-01-05 Composiciones de recubrimiento de polimero en emulsion con bajo contenido de voc.
JP2006551106A JP4857125B2 (ja) 2004-01-23 2005-01-05 ステントデリバリカテーテル
CA002553529A CA2553529A1 (fr) 2004-01-23 2005-01-05 Catheter de pose d'endoprothese
EP05704976A EP1706065A1 (fr) 2004-01-23 2005-01-05 Catheter de pose d'endoprothese

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/764,054 2004-01-23
US10/764,054 US7468070B2 (en) 2004-01-23 2004-01-23 Stent delivery catheter

Publications (1)

Publication Number Publication Date
WO2005072650A1 true WO2005072650A1 (fr) 2005-08-11

Family

ID=34795196

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/000150 Ceased WO2005072650A1 (fr) 2004-01-23 2005-01-05 Catheter de pose d'endoprothese

Country Status (5)

Country Link
US (2) US7468070B2 (fr)
EP (1) EP1706065A1 (fr)
JP (1) JP4857125B2 (fr)
CA (1) CA2553529A1 (fr)
WO (1) WO2005072650A1 (fr)

Cited By (10)

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JP2009508578A (ja) * 2005-09-16 2009-03-05 ウィルソン−クック・メディカル・インコーポレーテッド 二重金属製ステント導入器
WO2009050265A1 (fr) 2007-10-17 2009-04-23 Angiomed Gmbh & Co. Medizintechnik Kg Système de fourniture d'un dispositif auto-expansible pour pose dans une lumière corporelle
US9168164B2 (en) 2010-12-01 2015-10-27 C. R. Bard, Inc. Device to release a self-expanding implant
US9687370B2 (en) 2008-05-09 2017-06-27 C.R. Bard, Inc. Method of loading a stent into a sheath
US9687369B2 (en) 2009-12-03 2017-06-27 C.R. Bard, Inc. Stent device delivery system with an outer sheath polymeric reinforcement layer
US9717612B2 (en) 2009-12-03 2017-08-01 C.R. Bard, Inc. Stent device delivery system with a varying radial profile pull member
US9724216B2 (en) 2009-12-03 2017-08-08 C. R. Bard, Inc. Stent device delivery system with inwardly tapering stent bed
US9833349B2 (en) 2008-08-21 2017-12-05 C. R. Bard, Inc. Method of loading a stent into a sheath
US10271979B2 (en) 2008-12-31 2019-04-30 C. R . Bard, Inc. Stent delivery device with rolling stent retaining sheath
US10278845B2 (en) 2009-12-03 2019-05-07 C. R. Bard, Inc. Stent device delivery system with a heat shrink resistant support member

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JP4512362B2 (ja) 2001-07-06 2010-07-28 アンギオメット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コムパニー メディツィンテヒニク コマンデイトゲゼルシャフト 自己拡張式ステントの迅速プッシャ組立体及びステント交換形態を備えた運搬システム
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US7965719B2 (en) * 2002-12-11 2011-06-21 Broadcom Corporation Media exchange network supporting multiple broadband network and service provider infrastructures
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US20090105802A1 (en) 2009-04-23
CA2553529A1 (fr) 2005-08-11
EP1706065A1 (fr) 2006-10-04
JP2007518518A (ja) 2007-07-12
US20050165352A1 (en) 2005-07-28
JP4857125B2 (ja) 2012-01-18
US7468070B2 (en) 2008-12-23

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