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WO2005070398A3 - Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents - Google Patents

Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents Download PDF

Info

Publication number
WO2005070398A3
WO2005070398A3 PCT/IB2005/000156 IB2005000156W WO2005070398A3 WO 2005070398 A3 WO2005070398 A3 WO 2005070398A3 IB 2005000156 W IB2005000156 W IB 2005000156W WO 2005070398 A3 WO2005070398 A3 WO 2005070398A3
Authority
WO
WIPO (PCT)
Prior art keywords
solvents
pharmaceutical compositions
stabilized
candesartan cilexetil
cilexetil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2005/000156
Other languages
French (fr)
Other versions
WO2005070398A2 (en
WO2005070398A8 (en
Inventor
Romi Barat Singh
Girish K Karanth
Vishnubhotla Naga Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of WO2005070398A2 publication Critical patent/WO2005070398A2/en
Publication of WO2005070398A3 publication Critical patent/WO2005070398A3/en
Publication of WO2005070398A8 publication Critical patent/WO2005070398A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to stable pharmaceutical compositions that include candesartan cilexetil and one or more co-solvents.
PCT/IB2005/000156 2004-01-23 2005-01-21 Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents Ceased WO2005070398A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN127DE2004 2004-01-23
IN127/DEL/2004 2004-01-23
IN1506/DEL/2004 2004-08-16
IN1506DE2004 2004-08-16
IN2402/DEL/2004 2004-12-01
IN2402DE2004 2004-12-01

Publications (3)

Publication Number Publication Date
WO2005070398A2 WO2005070398A2 (en) 2005-08-04
WO2005070398A3 true WO2005070398A3 (en) 2006-03-30
WO2005070398A8 WO2005070398A8 (en) 2006-05-04

Family

ID=34811697

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/000156 Ceased WO2005070398A2 (en) 2004-01-23 2005-01-21 Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents

Country Status (1)

Country Link
WO (1) WO2005070398A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008030161A1 (en) * 2006-09-05 2008-03-13 Astrazeneca Ab Pharmaceutical composition comprising candesartan cilexetil
WO2008045006A1 (en) * 2006-10-11 2008-04-17 Fako Ilaclari A. S. Formulations of candesartan
EP2099431B1 (en) * 2006-11-28 2013-06-05 Laboratorios Liconsa, S.A. Stabilized solid pharmaceutical composition of candesartan cilexetil
WO2008068727A2 (en) * 2006-12-06 2008-06-12 Ranbaxy Laboratories Limited Pharmaceutical composition comprising candesartan cilexetil
WO2008084504A2 (en) * 2007-01-12 2008-07-17 Rubicon Research Private Limited Pharmaceutical compositions of angiotensin ii receptor blockers
EP1952806A1 (en) 2007-02-01 2008-08-06 Helm AG Process for the preparation of adsorbates of candesartan
PL384680A1 (en) * 2007-03-28 2008-09-29 Zak & Lstrok Ady Farmaceutyczn Pharmaceutical composition containing cylexyethyl candesarthan and its production method
CA2705625A1 (en) * 2007-08-01 2009-02-05 Teva Pharmaceutical Industries Ltd. Improved formulations of candesartan
DE102007052070A1 (en) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg candesartancilexetil
PL2165702T3 (en) 2008-09-17 2012-04-30 Helm Ag Stable and readily dissolved compositions of candesartan cilexetil prepared with wet granulation
DE102008059206A1 (en) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dosage form containing nifedipine or nisoldipine and an angiotensin II antagonist and / or a diuretic
ES2364011B1 (en) 2009-11-20 2013-01-24 Gp Pharm, S.A. CAPSULES OF PHARMACEUTICAL ACTIVE AND ESTERS OF POLYINSATURATED FATTY ACIDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES.
JP2013067574A (en) * 2011-09-21 2013-04-18 Teva Pharma Japan Inc Stabilized pharmaceutical composition
IN2014DN09045A (en) 2012-05-07 2015-05-22 Bayer Pharma AG
CN117442577B (en) * 2023-12-21 2024-03-15 山东则正医药技术有限公司 Candesartan cilexetil microchip and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546358A2 (en) * 1991-11-20 1993-06-16 Takeda Chemical Industries, Ltd. Pharmaceutical compositions with angiotensin-II-antagonistic activity
WO1997037688A2 (en) * 1996-04-05 1997-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination containing a compound having angiotensin ii and antagonistic activity
US6299904B1 (en) * 1997-05-27 2001-10-09 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546358A2 (en) * 1991-11-20 1993-06-16 Takeda Chemical Industries, Ltd. Pharmaceutical compositions with angiotensin-II-antagonistic activity
WO1997037688A2 (en) * 1996-04-05 1997-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination containing a compound having angiotensin ii and antagonistic activity
US6299904B1 (en) * 1997-05-27 2001-10-09 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation

Also Published As

Publication number Publication date
WO2005070398A2 (en) 2005-08-04
WO2005070398A8 (en) 2006-05-04

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