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WO2005069797A3 - Structures microfluidiques et procedes permettant d'integrer un composant fonctionnel a un dispositif microfluidique - Google Patents

Structures microfluidiques et procedes permettant d'integrer un composant fonctionnel a un dispositif microfluidique Download PDF

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Publication number
WO2005069797A3
WO2005069797A3 PCT/US2004/043945 US2004043945W WO2005069797A3 WO 2005069797 A3 WO2005069797 A3 WO 2005069797A3 US 2004043945 W US2004043945 W US 2004043945W WO 2005069797 A3 WO2005069797 A3 WO 2005069797A3
Authority
WO
WIPO (PCT)
Prior art keywords
functional component
microfluidic
integrating
methods
structures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/043945
Other languages
English (en)
Other versions
WO2005069797A2 (fr
Inventor
Blake Simmons
Linda Domeier
Noble Woo
Timothy Shepodd
Ronald F Renzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandia National Laboratories
Original Assignee
Sandia National Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandia National Laboratories filed Critical Sandia National Laboratories
Publication of WO2005069797A2 publication Critical patent/WO2005069797A2/fr
Publication of WO2005069797A3 publication Critical patent/WO2005069797A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C3/00—Assembling of devices or systems from individually processed components
    • B81C3/002—Aligning microparts
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C5/00—Manufacture of fluid circuit elements; Manufacture of assemblages of such elements integrated circuits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00—Manufacture or treatment of microstructural devices or systems
    • B81C2201/03—Processes for manufacturing substrate-free structures
    • B81C2201/034—Moulding
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/0076—Fabrication methods specifically adapted for microvalves using electrical discharge machining [EDM], milling or drilling
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/0078—Fabrication methods specifically adapted for microvalves using moulding or stamping
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0073—Fabrication methods specifically adapted for microvalves
    • F16K2099/008—Multi-layer fabrications
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Mechanical Engineering (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Hardware Design (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Injection Moulding Of Plastics Or The Like (AREA)

Abstract

Un moulage par injection est mis en oeuvre pour former des dispositifs microfluidiques dotés de composants fonctionnels intégrés. Un ou plusieurs composants fonctionnels sont placés dans une cavité de moule qui est ensuite fermée. La résine thermoplastique fondue est injectée dans le moule puis refroidie, permettant ainsi la formation d'un substrat solide incluant le ou les composants fonctionnels. Le substrat solide incluant le ou les composants fonctionnels est ensuite lié à un second substrat qui peut inclure des microcanaux ou d'autres caractéristiques.
PCT/US2004/043945 2004-01-08 2004-12-28 Structures microfluidiques et procedes permettant d'integrer un composant fonctionnel a un dispositif microfluidique Ceased WO2005069797A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/754,286 US7351380B2 (en) 2004-01-08 2004-01-08 Microfluidic structures and methods for integrating a functional component into a microfluidic device
US10/754,286 2004-01-08

Publications (2)

Publication Number Publication Date
WO2005069797A2 WO2005069797A2 (fr) 2005-08-04
WO2005069797A3 true WO2005069797A3 (fr) 2006-02-16

Family

ID=34739354

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/043945 Ceased WO2005069797A2 (fr) 2004-01-08 2004-12-28 Structures microfluidiques et procedes permettant d'integrer un composant fonctionnel a un dispositif microfluidique

Country Status (2)

Country Link
US (2) US7351380B2 (fr)
WO (1) WO2005069797A2 (fr)

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US9579649B2 (en) 2010-10-07 2017-02-28 Sandia Corporation Fluid delivery manifolds and microfluidic systems
EP2718017B1 (fr) 2011-06-06 2020-08-05 Corsolutions, LLC Interface fluidique
US9791080B2 (en) * 2012-03-12 2017-10-17 Idex Health & Science Llc Microfluidic interconnect
US20150316188A1 (en) * 2012-06-29 2015-11-05 University Of South Australia Fluid connection ports
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US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
JP6404822B2 (ja) 2012-10-23 2018-10-17 カリス ライフ サイエンシズ スウィッツァーランド ホールディングス ゲーエムベーハー アプタマーおよびその使用
CA2895847C (fr) 2012-12-19 2019-01-08 Caris Science, Inc. Compositions et procedes pour le criblage d'aptameres
BR112016004153A2 (pt) 2013-08-28 2019-09-17 Caris Life Sciences Switzerland Holdings Gmbh "método para caracterizar uma doença ou distúrbio, kit, composição, método para gerar uma biblioteca de entrada, oligonucleotídeo, pluralidade de oligonucleotídeos e método para identificar um aptâmero
CN104191548B (zh) * 2014-09-04 2017-04-19 齐鲁工业大学 一种透明胶带雕刻微流控芯片模具的快速制备方法
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WO2016145128A1 (fr) 2015-03-09 2016-09-15 Caris Science, Inc. Sondes oligonucléotidiques et utilisations de celles-ci
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Also Published As

Publication number Publication date
US20050151371A1 (en) 2005-07-14
US7351380B2 (en) 2008-04-01
WO2005069797A2 (fr) 2005-08-04
US8808588B1 (en) 2014-08-19

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