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WO2005065640A8 - Nouvelles compositions pour formes posologiques orales, et procede de preparation de telles compositions - Google Patents

Nouvelles compositions pour formes posologiques orales, et procede de preparation de telles compositions

Info

Publication number
WO2005065640A8
WO2005065640A8 PCT/IN2005/000003 IN2005000003W WO2005065640A8 WO 2005065640 A8 WO2005065640 A8 WO 2005065640A8 IN 2005000003 W IN2005000003 W IN 2005000003W WO 2005065640 A8 WO2005065640 A8 WO 2005065640A8
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
preparing
dosage forms
drug release
buccal dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2005/000003
Other languages
English (en)
Other versions
WO2005065640A1 (fr
Inventor
Rajesh Jain
Kour Chand Jindal
Sukhjeet Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panacea Biotec Ltd
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Priority to YUP-2005/0835A priority Critical patent/RS20050835A/sr
Publication of WO2005065640A1 publication Critical patent/WO2005065640A1/fr
Publication of WO2005065640A8 publication Critical patent/WO2005065640A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention se rapporte à de nouvelles compositions pour formes posologiques orales, qui contiennent de préférence un ou plusieurs médicaments à faible biodisponibilité, ou un ou plusieurs médicaments faisant l'objet d'une biotransformation hépatique présystémique importante. Les compositions selon l'invention permettent une libération prolongée du médicament dans la cavité buccale, et se présentent de préférence sous forme de compositions au goût masqué. L'invention concerne également un procédé de préparation de telles compositions.
PCT/IN2005/000003 2004-01-06 2005-01-05 Nouvelles compositions pour formes posologiques orales, et procede de preparation de telles compositions Ceased WO2005065640A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
YUP-2005/0835A RS20050835A (sr) 2004-01-06 2005-01-05 Sastavi bukalnih doznih oblika za produženo otpuštanje leka i postupak za njihovo dobijanje

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN24/DEL/2004 2004-01-06
IN26/DEL/2004 2004-01-06
IN26DE2004 2004-01-06
IN24DE2004 2004-01-06

Publications (2)

Publication Number Publication Date
WO2005065640A1 WO2005065640A1 (fr) 2005-07-21
WO2005065640A8 true WO2005065640A8 (fr) 2005-12-08

Family

ID=34751866

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2005/000003 Ceased WO2005065640A1 (fr) 2004-01-06 2005-01-05 Nouvelles compositions pour formes posologiques orales, et procede de preparation de telles compositions

Country Status (2)

Country Link
RS (1) RS20050835A (fr)
WO (1) WO2005065640A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007096906A2 (fr) * 2006-02-27 2007-08-30 Panacea Biotec Ltd. Nouvelles compositions bucco-adhésives et procédé d'élaboration desdites compositions
CN100450548C (zh) * 2006-12-22 2009-01-14 江苏奥赛康药业有限公司 一种波拉克林树脂组合物的口腔贴片及其制备方法
WO2008155620A1 (fr) * 2007-06-20 2008-12-24 Develco Pharma Schweiz Ag Forme posologique contenant une matrice dispersible de granulés à libération entretenue
US8133506B2 (en) 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
EP3108876A1 (fr) * 2011-10-13 2016-12-28 Jaleva Pharmaceuticals LLC Procédés et compositions pour administration rapide d'agents actifs par la bouche
EP2906210A4 (fr) * 2012-10-12 2016-06-08 Jaleva Pharmaceuticals Llc Procédé de préparation de teintures de résine
EP2925273A4 (fr) 2012-11-28 2016-08-31 Jaleva Pharmaceuticals Llc Applicateur à deux chambres
CN105232502A (zh) * 2015-02-10 2016-01-13 万全万特制药江苏有限公司 含波拉克林钾和盐酸氟西汀复合物的口崩片及其制备方法
ES2983269T3 (es) * 2015-07-23 2024-10-22 Athena Pharmaceutiques Sas Composición de zolpidem y proceso de preparación de la misma
CN114344241B (zh) * 2021-12-15 2024-01-30 悦康药业集团安徽天然制药有限公司 一种聚丙烯酸树脂改性吸附药物载体及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238072B (it) * 1990-01-19 1993-07-03 Sclavo Spa Composizioni farmaceutiche e forme di dosaggio per la somministrazione orale di calcitonina
AU3455297A (en) * 1996-07-11 1998-02-09 Farmarc Nederland Bv Pharmaceutical composition containing acid addition salt of basic drug
DE19932603A1 (de) * 1999-07-13 2001-01-25 Gruenenthal Gmbh Wirkstoffhaltiger Mehrschichtfilm aus in situ vernetzten hydrophilen Polymeren
JP2004532838A (ja) * 2001-03-02 2004-10-28 ブリストル−マイヤーズ スクイブ カンパニー メラノコルチン受容体のモデュレーターとして有用な化合物及びそれを含む製薬組成物
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device

Also Published As

Publication number Publication date
RS20050835A (sr) 2007-08-03
WO2005065640A1 (fr) 2005-07-21

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