WO2005058157A1 - Nerve activity controller and nerve activation control method - Google Patents

Abstract

A nerve activity controller comprises a laser unit, an application control unit, and an application position control unit. A laser beam generated by the laser unit is applied to a predetermined nerve portion of an organism to change the activity of a nerve. By controlling at least the on/off of the laser beam, the application pattern of the laser beam can be controlled and the position of the nerve portion to which the laser beam is applied can be changed. The phenomenon that the activity of a nerve cell can be temporarily changed can be stably induced.

Description

 Specification

Neural activity control device and neural activity control method

 Technical field

 The present invention relates to a nerve activity control device and a nerve activity control method using laser light irradiation, which change the activity of nerves of the cerebral nerves and limbs such as humans and animals to elucidate nerve functions and suppress seizures. Background art on available mounting methods

 Irradiation of the auditory cortex of the animal's brain with laser light inactivated the neural activity at the irradiated site, and found that when the irradiation was completed, the site recovered its original activity. Such a phenomenon is described, for example, in “Maki, Rikimaru, and Factory Changes in the activity of the lower hill neurons due to the inactivation of the auditory cortex using laser light”, Materials of the Acoustical Society of Japan Acoustical Society, January 2, 2004. 5th, Vol. 32, No. 1, p. 1

_ 4 "," Maki, Rikimaru, "The role of the centrifugal tract from the auditory cortex in the formation of temporal response patterns of inferior colliculus cells" Proceedings of the Acoustical Society of Japan, March 2002, p. 484, and Sumita, Rikimaru, "Experiment on the inactivation of the auditory cortex using near-infrared laser light" Materials of the Acoustical Society of Japan Acoustical Society of Japan, January 14, 2002 3, Vol. 32, No. 10, p. 545-550 ". Disclosure of the invention Conventionally, to change the behavior of nerves such as the auditory cortex of the brain

There is a method to administer drugs such as U-ring and muscimol, but the site of effect is limited due to the diffusion of the drug. <The effect lasts for a long time after administration. A phenomenon in which the auditory evoked response was attenuated and a phenomenon in which hyperpolarization of the nerve action potential occurred was discovered, but the details of its operation and how to use it were unknown, and such phenomena were stabilized. It is anticipated that if the device and method for generating the nerve are known, it is expected that the way of elucidation and utilization of the movement will be opened. In the present invention, the device and method for changing the activity of the nerve in a desired form are described. Provide a device and method that can make certain effects appear reproducibly and reliably by changing the activity.

 In order to solve the above problem, the neural activity control device and the neural activity control method of the present invention use the following means.

 (1) Laser unit that outputs laser light and irradiation control unit that controls the output of laser light from the laser unit and laser light from the laser unit

—Equipped with an irradiation position control unit that controls the irradiation position of the light. 刖 ti A neural activity control device that irradiates a predetermined nerve part of the living body with laser light generated by the laser unit and changes the nerve activity.

(2) The first input receiving unit that receives a first input is further provided, and the irradiation control unit determines an irradiation pattern of the laser light based on the first input. Neural activity control device (3) A second input receiving unit for receiving a second input is further provided, and the irradiation position control unit determines a position to be irradiated with the laser beam based on the second input (1) Or (2) The neural activity control device according to any one of (1) to (4).

 (4) The nerve activity control device according to any one of (1) to (3), wherein the irradiation control unit performs ON and OFF control of the laser light output from the laser unit.

 (5) The neural activity according to any one of (1) to (3), wherein the irradiation control unit is a switch that controls the laser light output from the laser unit to OFF and OFF. Control device.

 (6) The nerve activity control device according to any one of (1) to (3), wherein the irradiation control unit controls an irradiation pattern of a laser beam output from the laser unit.

 (7) The irradiation position control unit is an adjusting member that enables the position of the nerve part to be irradiated by the laser unit to be changed. (1) to (3) The neural activity control device according to the above.

 (8) A reaction observation unit for observing any one of the action of the living body or the reaction, the action or the reaction of the nerve site, or the action of the nerve at a site other than the nerve site of the living body, or the reaction is further provided. The nerve activity control device according to any one of (1) to (3).

(9) The nerve activity control device according to any one of (1) to (3), wherein the plurality of laser beams are irradiated from different positions so as to converge on a predetermined part of a living body. (10) The laser light generated by the laser unit is irradiated to a predetermined nerve part of the living body to change the abnormal state of the living body, or to change the normal hanging state. (1)

(9) The nerve activity control device according to any one of (1) to (10).

 (11) A laser beam generated by the laser part is irradiated to a predetermined neural part of the brain to stop or reduce seizures such as epilepsy. (1) (9) ) Neural activity control device

 (1 2) (1) (9) Any one of (1) and (9) above is characterized in that a laser beam generated by the laser section is irradiated to a predetermined nervous site of the brain to perform treatment or examination of motor function. Nerve activity control device

 (13) The laser beam generated by the laser section is irradiated to a predetermined neural site of the brain, and the center is localized.

(1) (9) The neural activity control device according to any of the above,

 (14) The laser beam generated by the laser section is irradiated to a predetermined nervous site of the brain, and the treatment or examination of the dysphagia is performed. (1) (9) Any Activity control device

(15) The laser beam generated by the laser section is irradiated to a predetermined god region of the brain, and treatment or examination for visual loss is performed. Nerve activity control device

(16) 刖 The laser light generated by the laser part is irradiated to a predetermined nervous site in the brain to treat or test for somatic %% disorder. (1) to (9), wherein the neural activity control device according to any one of (1) to (9).

(17) The nerve activity according to any one of (1) to (9), wherein a laser beam generated by the laser unit is irradiated to a predetermined nervous site of the brain to treat or test pain. Control device.

(18) The laser beam generated by the laser section is irradiated to a predetermined neural site of the brain to perform treatment or examination for sensory disturbances. (1) to (9). Neural activity control device

 (19) A nerve activity control device, which irradiates a predetermined nerve part of a living body with a laser beam to change an abnormal state of the living body, or changes a normal state of the living body.

 (20) A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with laser light to stop seizures such as epilepsy

(21) A neural activity controller, which irradiates a predetermined nerve part of the brain with laser light to perform treatment or detection of motor function.

 (22) A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with a laser beam to localize a speech center.

 (23) A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with laser light to treat or detect aphasia

(24) Nerve activity control characterized by irradiating a predetermined nerve part of the brain with a laser beam and treating or examining a visual loss blade apparatus.

 (25) A nerve activity control device, which irradiates a predetermined nerve part of the brain with laser light to perform treatment or examination for somatosensory disorders.

 (26) A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with a laser beam to perform treatment or examination of sickness

(27) A nerve activity control device characterized by irradiating a predetermined nervous site of the brain with laser light and treating or examining a perceptual disorder.

 (28) Cap-shaped neural activity control device that irradiates laser light to the brain and obtains the first electric power

Brief description of drawings

 FIG. 1 is a block diagram of an embodiment of the nerve activity control device of the present invention.

 FIG. 2 is a block diagram of another embodiment of the nerve activity control device of the present invention.

 FIG. 3 is a diagram showing an example of irradiation position control and irradiation control of the nerve activity control device of the present invention.

 FIG. 4 is a diagram of an example of irradiation position control of the nerve activity control device of the present invention.

 FIG. 5 is a diagram of another embodiment of the nerve activity control device of the present invention.

FIG. 6 shows another embodiment of the neural activity control device according to the present invention. There is a figure

 FIG. 7 is a diagram showing another embodiment of the nerve activity control device of the present invention.

 Hereinafter, an embodiment of a nerve activity control device and a nerve activity control method according to the present invention will be described with reference to the drawings, in a case where components denoted by the same reference numerals perform the same operation in the embodiment. May omit the description of Renos,

 (Implementation form 1)

 FIG. 1 is a diagram showing an embodiment of a nerve activity control apparatus according to the present invention. In FIG. 1, an infrared laser beam 2 generated by a laser unit 1 is irradiated onto a desired nerve site of a living body 6. . The irradiation control unit 3 supplies a driving current to the laser unit 1 and controls the light emission time and the light emission intensity of the laser unit 1. Irradiation control unit

4 controls the position irradiated by the laser light 2. That is, position control such as the position of the laser unit 1 and the direction of the laser light 2 is performed so that the laser light 2 is irradiated onto a desired nerve site. The reaction observation section 5 observes and observes the reaction of the living body 6.

The irradiation position control unit 4 is a tool for fixing the laser unit 1 on a pedestal, in a simple case. It may be an adjusting member for adjusting the distance between the laser part 1 and the nerve cell part of the living body 6 and the irradiation direction of the laser light 2. The pedestal also serves as an adjustment member so that the distance between the unit and the irradiation direction of the laser beam 2 can be adjusted. 4

 The irradiation control unit 3 has a function of supplying a current for driving the laser unit 1 and a function of generating a laser drive time waveform. The pulse generation is performed by a pulsed electric signal. It may be done by switching the toggle switch to 0 NOFF.

 The reaction observation unit 5 is for observing a reaction of a nerve at a predetermined position of the living body 6. For example, an electrode is inserted into a nerve at a predetermined position of the living body 6 to measure a reaction potential of the nerve. System. The reaction observation unit 5 observes the movement of the living body 6 illuminated by the laser light, or the reaction of the living body 6, or the movement of the nerve at a site other than the three self-neural sites, or the reaction.

 As the laser light, a wavelength of 830 nm is used. The nerve cells that irradiate the laser light include, for example, cerebral nerve cells, nerve cells of the spinal cord, and other peripheral parts such as limbs. The target is nerve cells.

According to the present embodiment, by irradiating the nerve cells of the 6 species of the living body with laser light, the laser light can be used to efficiently elucidate the nerve function, and the irradiation is performed. It is easy to limit the position to about ^{0.1 Lm Δ,} so that it does not affect the periphery of nerve cells

 As shown in FIG. 6, the reaction observation unit 5 observes (records) the movement of the living body 6 and the like.

5 may be used.The observer may directly observe the living body 6. The irradiation control unit 3 can store the irradiation pattern which is the input received by the input receiving unit (not shown).

The same irradiation pattern can be generated repeatedly, so that accurate experiments can be performed accurately or efficiently.Specific irradiation patterns are generated a predetermined number of times at predetermined time intervals. Is also good. In this case, the irradiation control unit 3 includes the shape of the irradiation turn, for example, the rising speed of the laser beam, the intensity, the time ft, the falling speed, the intensity change shape in the middle, the repetition period.

An input receiving unit (not shown) that receives input of control parameters such as the number of repetitions, the number of repetitions, and the like, and a storage unit (not shown) that stores the input irradiation pattern are provided. A plurality of irradiation patterns may be stored and selected for use. Such an irradiation pattern may be generated by a computer such as a personal computer to control the laser drive current. In this case, the personal computer is also the irradiation control unit.

It should be noted that the input means received by the input receiving unit is not limited to a keypad or a mouse. The input receiving unit can be usually realized by such input means as a software, a software, or the like.

 Regarding the irradiation position control of the irradiation position control unit 4, a second input ′ receiving unit (not shown) for receiving an input of a desired position is provided, and the irradiation position control unit 4 performs laser irradiation based on the second input. The irradiation position of light may be determined (

 (Embodiment 2)

Note that in FIG. 1, the observation results of the reaction observation It may be input to control unit 3. That is, the irradiation pattern of the irradiation control unit 3 may be changed according to the observation result of the reaction observation unit 5. The dotted line between the reaction observation unit 5 and the irradiation control unit 3 in FIG. 1 indicates such a relationship.

 (Embodiment 3)

 Next, FIG. 2 is a diagram showing another embodiment of the nerve activity control device of the present invention. In FIG. 2, an infrared laser beam 2 generated by a laser unit 1 is irradiated on a brain nerve at a desired position of a brain 26 of a living body. The irradiation control unit 3 supplies a driving current to the laser unit 1 to control the light emission time and the light emission intensity of the laser unit 1. The irradiation position control unit 4 controls the position of the laser unit 1 or the laser light 2 so that the laser light 2 is irradiated on a desired cranial nerve. The reaction observation unit 5 observes the reaction of the brain 26 <

 The irradiation control unit 3 and the irradiation position control unit 4 are the same as those described in the first embodiment.

 In FIG. 2, the reaction observing section 5 is for observing the reaction of the cranial nerve, and the electrode is inserted into the cranial nerve at a predetermined position to measure, display, and record the reaction potential of the nerve.

 According to the present embodiment, the cranial nerve function can be efficiently clarified by laser light irradiation.

In the case of humans, the area of the brain 26 to be irradiated is the S area, the 刖 frontal area (frontal association area), the motor area, the somatosensory area, the parietal association area, the primary visual area, the temporal association area (lower area). Temporal lobe), the auditory cortex, etc. The anterior motor area and the frontal eye area before the central anterior sulcus may also be irradiated. The frontal eye area is the central point where the eyes turn sideways, R; K ~ π, very important. Judgment as to whether the language field should be left or right can be made reliably.

 (Embodiment 4)

 In Embodiments 1 to 3 above, as shown in FIG. 3, the irradiation position control section 34 may control the irradiation position by acting on the laser beam 2. In FIG. 3 (A), the laser beam from the laser section 1 is condensed or desired by the optical section 31.

-Shape it into a shape. When collecting light, a well-known lens is used / this optical system can be applied. In order to obtain a desired beam shape, an optical element such as an aspheric lens or a polarizing grating may be used in the optical system. Further, as shown in FIG. 3B, the beam may be shaped using a U-shaped member having a desired shape. It is only necessary to use a switch that matches the shape of the target nerve cell and the shape of the region to be irradiated in each territory such as the visual or auditory cortex. The irradiation position control unit 34 controls the lens, the polarization grating, the slit, etc. of the optical unit 31 so that the beam shape becomes a desired shape. FIG. 3 (C) shows the irradiation control unit. 3 is an example of a drive current turn that is supplied when the laser unit 1 is driven between T1 to T2 and T3 to Τ4.

If the irradiation pattern is stored in the irradiation control unit 3, the irradiation pattern as shown in FIG. 3 (C) can be repeatedly generated, so that a confirmation experiment can be performed. The irradiation pattern may be accurately and efficiently performed, and the predetermined irradiation pattern may be generated a predetermined number of times at a predetermined time interval. In this case α, the irradiation control unit 3 includes the shape of the irradiation pattern, for example, the laser light. Chi fast degree fast-strength change shape Ό return Shi period in the middle of the time length falling under the rising, the input accepting unit that accepts a control para main evening inputs, such as number of iterations (not shown) and the set irradiation Ha ⁰ The irradiation pattern is generated by a computer such as a personal computer, and the laser drive current is generated by a computer such as a personal computer (<storage section (not shown)). I try to control it.

 Regarding the irradiation position control of the irradiation position control unit 34, a second input receiving unit (not shown) for receiving an input of a desired position is provided, and the irradiation position control unit 4 transmits the laser light based on the second input. The irradiation position may be determined,

 The lower stream of the driving flow may be controlled by associating it with the shape of the beam, and the arrow of the line indicates that the relationship of such an easy opening is provided.

 (Embodiment 5)

FIG. 4 shows another example of the irradiation position control unit 4. Reference numeral 41 denotes an arc-shaped rail. A sliding unit 42 is fitted to the rail 41, and moves on an arc. The slider 43 is attached to the sliding portion 42. By moving the sliding part 4 2 on which the laser part 1 is mounted on the laser 43, the laser light of the laser part 1 is transmitted to a desired part 44 on the surface of the brain 26. The skull and scalp are not shown for simplicity, but a hole is made in the head if necessary.The sliding part 42 must be moved manually. Or go electromechanically using Is also good.

 However, the mechanism for the above movement is not limited to the above structure, and the rail 41 may be moved in the vertical direction of the paper of FIG. 4. 4 1 may be made to rotate in the vertical direction in FIG. 4 around the fulcrum, with a fulcrum at both ends.

 (Embodiment 6)

 FIG. 5 shows an example in which a plurality of laser beams are emitted to the nerve site C 03, and an arc-shaped rail 51, which is an example of emitting the laser light, is fitted with a sliding portion 52, and the sliding portion 5 is formed. Inside the arc of two multiple V5 3

In this figure, four lasers are X-rayed. Ο Each laser beam is

The direction can be adjusted so as to irradiate a desired portion 54 of 26. Brain cells are illuminated with laser light, usually require a craniotomy to make a hole in the skull.A hole that does not make a hole in the skull α に For skin or skull, etc. Although some external lines are absorbed, as in the present embodiment, if a large number of laser beams are occupied and concentrated in one area, a sufficient amount of laser beams can be absorbed in a desired region (brain). It is possible to irradiate ¾) at a deep part of the skin, because the laser light absorbed by the skin and the like on the way is dispersed on the white skin and kept low < In the case of near-infrared light having a wavelength of about 700 nm to about 100 nm, which causes a burn or the like, it has a relatively high permeability to the skin, the skull, and the like. Suitable for. If the wavelength is too short, it is reflected on the surface of the skin, skull, and brain, and if it is too long, it is absorbed by water in the skin and other cells. Water

 It is possible to study the function of the nerve cells inside the brain 26 by emitting laser light to the nerve cells inside the brain 26 <

 The laser beam 53 may be arranged linearly or two-dimensionally. A planar light emitting laser beam may be emitted by a lens.

 (Embodiment 7)

 FIG. 7 is a cross-sectional view and a plan view seen from below of an example in which the nerve activity control device of the present invention is formed in a hat shape worn by a person. Provide 3 reviews

The inside of the helmet 71, which can irradiate the head with the laser beam 72, detects the minute electrokinetic energy 1 generated by cranial nerves as a signal. The sensor 75 in which the sensor 75 is placed may be one or more.

In Fig. 5, it is possible to use a microelectrode to detect the elongation of ft-like activity by inserting an electrode from the craniotomy of the brain 26 into the cells of the brain 26. The electrode may be stimulated into the brain cells at the laser irradiation position by placing 5 on the laser cut 73 and using a high-sensitivity magnetic sensor as the sensor 75.

However, even if a minute change in the activity of brain cells is detected and extracted, a change in the electromagnetic field due to the action potential can be detected through the skull and skin, so that it is not necessary to open the skull.

Suitable for long time inspection,

 The focus is on the location A of the brain cells to be considered.

Σ In order to be able to move it, it is necessary to make a number of holes on the helmet 71, which is attached to the helmet 71 via the position adjustment brackets shown in the irradiation position controller 74. Now, it is sufficient to select 1 of the above holes and fix the laser beam 73 by the screw mechanism of the position adjusting bracket.

 The laser unit 73 is provided with one or more lasers. Multiple fields 設置 Installed so that each laser beam is focused at a desired position on brain 26

 The irradiation of the laser beam 2 is controlled by the irradiation control unit 3 as described above.

 In order to make it easier to mount the laser unit 73 and the sensor 75, check the irradiation position of the laser light, and perform rescue, a number of holes other than the mounting holes are provided on the hermet 71. Holes may be provided. It may be a net. The helmet 73 may be made of a clear material.

 Note that, in the present embodiment, the sensor 75 may be removable. That is, the helmet 71 has no sensor 75 attached thereto. The sensor 75 can be mounted so that the electrical signal can be detected by mounting it.

 By doing so, it becomes possible to irradiate the cranial nerve with laser light and observe the reaction of the cranial nerves at once, and to move while wearing the remet.

The sensor 75 may be attached to the hermet via a spring so as to be in close contact with the head. (Embodiment 8)

 The following processing can be performed by using the nerve activity control device according to the present invention and the nerve activity control method using the nerve activity control device of each of the above embodiments.

 By irradiating a laser beam generated by the laser unit to a predetermined nerve part of the living body, a neural activity control method that changes the abnormal state of the living body can be used to elucidate the cause of the abnormal state of the living body or to detect the abnormal state. Management is done. Conversely, it is also possible to illuminate the nerves in the normal state and change the nerve cells from the normal state to study the functions of the nerves

In addition, by reducing the activity of nerve cells, it is possible to paralyze predetermined functions, to produce effects similar to anesthesia, and to reduce or reduce pain. Become. In addition, it is possible to use the neural activation control method to stop seizures such as epilepsy by irradiating the laser light generated by the laser part to a predetermined neural part of the brain for diagnosis and treatment. is there. In addition to epilepsy, treatment and examination of motor function, localization of speech center (examination of position), treatment and examination of aphasia, treatment and examination of visual agnosia, treatment and examination of somatosensory disorders, pain treatment Activity and examination, treatment of sensory disorders, examinations, etc., the apparatus and method of the present invention provide a neural activity control device and a neural activity control method for any of these treatments and examinations. It can be done. Since the effect of laser light on the cranial nerves is reversible, the activity of the nerve to be irradiated returns to the state before irradiation in a short time after laser light irradiation, but in the brain where the above abnormal state persists The effect of temporarily blocking a part of the system, such as positive feedback, can be expected to have the effect of stopping abnormal conditions and seizures.

Availability on

 The neural activity controller and the neural activity controlling method according to the present invention elucidate the functions of nerve cells in living organisms, including cranial nerves of animals and humans, and elucidate the relationship between nerve cells. Attack by the action of the nervous system. It may be used in fields such as arrest, treatment of motor function, examination and treatment of PP center, treatment and examination of aphasia, treatment of visual agnosia, examination of treatment and treatment of somatic disorder Inspections Pain treatments and inspections There is also potential use in iS ^ disorder treatments and other fields such as inspections.

Claims

The scope of the claims  1 • A laser unit that outputs laser light, an irradiation control unit that controls the output of laser light from the laser unit, and an irradiation position control that controls the position that the laser light from the laser unit irradiates. A nerve unit that irradiates a predetermined nerve site of a living body with laser light generated by the laser unit and changes the activity of the nerve; 2 • A first input receiving unit for receiving a first input is further provided. The irradiation control unit determines an irradiation pattern of the laser light based on the first input. The nerve activity control device according to the item.  3 • A second input receiving unit that receives a second input is further provided, and the irradiation position control unit determines a position to be irradiated with the laser beam based on the second input. God: Sutra: Activity control device as described in either item 1 or claim 2. 4. The nerve activation device according to claim 1, wherein the irradiation control unit controls ON / OFF of the laser light output from the laser unit. 5. Control device m 5. The irradiation control unit according to claim 1, wherein the irradiation control unit is a switch that performs o NOFF control on the laser beam output from the laser unit. 6. Neuroactivity control device.  6-The irradiation control unit controls an irradiation pattern of a laser beam output from the laser unit. The neural activity control device according to any one of claims 1 to 3. 1 place  New  7. The irradiation position control unit is a perimeter member that enables the position of the nerve unit irradiated by the self-resonant laser unit to be changed. The neural activity control device according to any one of the third to third aspects.  8. A reaction observing unit for observing any of the above-mentioned movement of the living body or the reaction, the movement of the nerve unit of the HU, or the reaction of the god of the part of the living body other than the nerve unit or the reaction. The neural activity control device according to any one of claims 1 to 3, which is provided.  9. The laser unit according to claim 1, wherein the laser unit irradiates the plurality of laser beams from different positions so as to converge on a predetermined nerve part of a living body. Nervous activity control device described in any one of m  10. The laser beam generated by the laser unit is irradiated to a predetermined nervous site of a living body to change an abnormal state of the mBci living body, or to change a normal state of the living body. Nerve activity control according to any of Paragraphs 1 to 9 ¾ Nes Is.  11. Claims Claims 1 to 9 wherein the laser beam generated by the laser unit is irradiated to predetermined nerves of the brain to stop or reduce seizures such as epilepsy. Item 25. The nerve activity control device according to any one of the above. 1 2. The laser beam generated by the laser unit is irradiated to a predetermined nerve site in the brain to perform treatment or examination of motor function. The nerve activity control device according to any one of claims 1 to 9, wherein the control device is a nerve activity control device.  13. The claim according to claim 1, wherein the laser beam generated by the laser section is irradiated to a predetermined nerve site of the brain to localize the speech center. Nerve activity control device according to any of  14. The method according to claim 1, wherein the laser beam generated by the laser section is irradiated to a predetermined god site of the brain to treat or test for aphasia. The nerve activity control device according to any one of items 9 to.  15. Claims 1 to ei, characterized in that the laser light generated by the laser part is irradiated to a predetermined nerve part of the brain to treat or test for visual agnosia. The nerve activity control apparatus according to any one of claims 9 to 13.  6 範 囲 範 囲 範 囲 1 範 囲 部 範 囲 範 囲 範 囲 範 囲 6 範 囲 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6. The neural activity control device according to any one of items 9 to 17  17. The method according to claim 1, wherein the laser light generated by the pd laser portion is irradiated to a predetermined nerve site of the brain to treat or test for pain. Nerve activity control device according to any one of the items in the range 9 18. Claims from claim 1 characterized in that the laser light generated by the HU Bid laser part is irradiated to a predetermined nerve part of the brain to perform treatment or examination for sensory disorders. Any of paragraph 9 of the scope Nervous activity control device [  19. A nerve activity control device which irradiates a predetermined nerve part of a living body with laser light to change the abnormal state of the living body or to change the normal state. .  20. A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with laser light to stop seizures such as epilepsy. 2 1. A nerve activity control device characterized by irradiating a predetermined neural part of the brain with laser light to treat or test motor function.  22. A neural activity control device characterized by irradiating a predetermined neural part of the brain with laser light to localize the language hearse.  23. A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with a laser beam and performing a test for aphasia or an aphasia. 24. A neural activity control device characterized by irradiating a predetermined neural part of the brain with laser light to perform treatment or examination for visual agnosia. 25. A neuroactive control coat m, which is characterized by irradiating a predetermined nerve site of the brain with laser light to treat or test for somatosensory disorders.  26. A nerve activity control device characterized by irradiating a predetermined nerve part of the brain with laser light to perform pain treatment or examination. 27. A nerve activity control device characterized by irradiating a predetermined neural part of the brain with laser light to perform oral treatment or examination for sensory disturbances 2 8. A Φ-needle-shaped neural activity controller that irradiates the brain with laser light and acquires electrical signals  2 9. The laser light to irradiate a predetermined nerve part of the living body is a plurality of laser lights, and the laser light is irradiated from different positions to converge on the predetermined nerve part of the living body. Claim 1 Nerve activity control according to any one of Items 28 to 28  30. A position determining step for determining the position to irradiate the laser light, and a laser light output step for outputting the laser light at the specified position are provided. A nerve activity control method that changes nerve activity by irradiating a predetermined nerve site ¾ 3 1. In the laser light output step V, the laser light that irradiates a predetermined nerve part of the living body is a plurality of laser lights. 30. The method for controlling nerve activity according to claim 30, wherein the irradiation is performed so that the light is focused on a nerve site.