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WO2005051362A3 - Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating - Google Patents

Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating Download PDF

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Publication number
WO2005051362A3
WO2005051362A3 PCT/IB2004/003865 IB2004003865W WO2005051362A3 WO 2005051362 A3 WO2005051362 A3 WO 2005051362A3 IB 2004003865 W IB2004003865 W IB 2004003865W WO 2005051362 A3 WO2005051362 A3 WO 2005051362A3
Authority
WO
WIPO (PCT)
Prior art keywords
enteric coating
separating layer
active core
optional separating
benzimidazole compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2004/003865
Other languages
French (fr)
Other versions
WO2005051362A2 (en
Inventor
Vivek Mahendrakumar Dubey
Visingiri Venkat Ram Mohan Rao
Abhijit Mukund Deshmukh
Sanjeev Kumar Sethi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Priority to CA002547398A priority Critical patent/CA2547398A1/en
Publication of WO2005051362A2 publication Critical patent/WO2005051362A2/en
Publication of WO2005051362A3 publication Critical patent/WO2005051362A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to stable oral benzimidazole compositions and processes for their preparation.
PCT/IB2004/003865 2003-11-28 2004-11-24 Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating Ceased WO2005051362A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002547398A CA2547398A1 (en) 2003-11-28 2004-11-24 Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1494DE2003 2003-11-28
IN1494/DEL/2003 2003-11-28

Publications (2)

Publication Number Publication Date
WO2005051362A2 WO2005051362A2 (en) 2005-06-09
WO2005051362A3 true WO2005051362A3 (en) 2005-10-20

Family

ID=34631112

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/003865 Ceased WO2005051362A2 (en) 2003-11-28 2004-11-24 Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating

Country Status (2)

Country Link
CA (1) CA2547398A1 (en)
WO (1) WO2005051362A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0509971A (en) * 2004-04-15 2007-10-02 Reddys Lab Inc Dr a pharmaceutical dosage form, tablet and preparation method
ITMI20062290A1 (en) * 2006-11-28 2008-05-29 Monteres S R L TABLETS STABLE WITH STORAGE BASED ON BENZIMIDAZOLE DERIVATIVES COATED WITH GASTRO-RESISTANT FILM
KR101907116B1 (en) * 2016-07-25 2018-10-11 한미약품 주식회사 Pharmaceutical Formulation with Improved pH-Dependent Drug Release Properties, Comprising Esomeprazole, or Pharmaceutically Acceptable Salt thereof
KR101877350B1 (en) * 2016-10-28 2018-08-09 한미약품 주식회사 Combined capsules containing esomeprazole and a process for the preparation thereof
BR112020003077A2 (en) * 2017-09-28 2020-08-25 Hanmi Pharm. Co., Ltd. pharmaceutical composition and method for preparing the pharmaceutical composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5035899A (en) * 1988-05-18 1991-07-30 Eisai Co., Ltd. Peroral preparation of acid-unstable compound
WO1998019668A1 (en) * 1996-11-06 1998-05-14 Sharmatek, Inc. Delayed delivery system for acid-sensitive drugs
EP1004305A1 (en) * 1998-04-20 2000-05-31 Eisai Co., Ltd. Stabilized compositions containing benzimidazole-type compounds
US6274173B1 (en) * 1995-07-05 2001-08-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
US20020128293A1 (en) * 1998-05-28 2002-09-12 Ashok Rampal Stable oral pharmaceutical composition containing omeprazole

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5035899A (en) * 1988-05-18 1991-07-30 Eisai Co., Ltd. Peroral preparation of acid-unstable compound
US6274173B1 (en) * 1995-07-05 2001-08-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
WO1998019668A1 (en) * 1996-11-06 1998-05-14 Sharmatek, Inc. Delayed delivery system for acid-sensitive drugs
EP1004305A1 (en) * 1998-04-20 2000-05-31 Eisai Co., Ltd. Stabilized compositions containing benzimidazole-type compounds
US20020128293A1 (en) * 1998-05-28 2002-09-12 Ashok Rampal Stable oral pharmaceutical composition containing omeprazole

Also Published As

Publication number Publication date
CA2547398A1 (en) 2005-06-09
WO2005051362A2 (en) 2005-06-09

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