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WO2005044849A3 - Lp mammalian proteins; related reagents - Google Patents

Lp mammalian proteins; related reagents Download PDF

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Publication number
WO2005044849A3
WO2005044849A3 PCT/US2004/019099 US2004019099W WO2005044849A3 WO 2005044849 A3 WO2005044849 A3 WO 2005044849A3 US 2004019099 W US2004019099 W US 2004019099W WO 2005044849 A3 WO2005044849 A3 WO 2005044849A3
Authority
WO
WIPO (PCT)
Prior art keywords
mammalian proteins
related reagents
reagents
mammalian
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/019099
Other languages
French (fr)
Other versions
WO2005044849A2 (en
Inventor
Jai Pal Singh
Asavari Prasad Wagle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of WO2005044849A2 publication Critical patent/WO2005044849A2/en
Publication of WO2005044849A3 publication Critical patent/WO2005044849A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Isolated and/or recombinant compositions related to Factor VIIa, reagents related thereto are provided. Methods of using said reagents and diagnostic kits are also provided.
PCT/US2004/019099 2003-08-05 2004-07-22 Lp mammalian proteins; related reagents Ceased WO2005044849A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49249903P 2003-08-05 2003-08-05
US60/492,499 2003-08-05

Publications (2)

Publication Number Publication Date
WO2005044849A2 WO2005044849A2 (en) 2005-05-19
WO2005044849A3 true WO2005044849A3 (en) 2005-08-04

Family

ID=34572730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019099 Ceased WO2005044849A2 (en) 2003-08-05 2004-07-22 Lp mammalian proteins; related reagents

Country Status (1)

Country Link
WO (1) WO2005044849A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2668411C (en) 2006-11-02 2020-02-25 Acceleron Pharma Inc. Alk1 receptor and ligand antagonists and uses thereof
US8642031B2 (en) 2006-11-02 2014-02-04 Acceleron Pharma, Inc. Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof
US10059756B2 (en) 2006-11-02 2018-08-28 Acceleron Pharma Inc. Compositions comprising ALK1-ECD protein
AU2009241755B2 (en) 2008-05-02 2015-10-01 Acceleron Pharma Inc. Methods and compositions based on ALK1 antagonists for modulating angiogenesis and pericyte coverage

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200421A2 (en) * 1985-04-17 1986-11-05 Zymogenetics, Inc. Expression of factor VII activity in mammalian cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200421A2 (en) * 1985-04-17 1986-11-05 Zymogenetics, Inc. Expression of factor VII activity in mammalian cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NICOLAISEN E M: "GENERATION OF GLA-DOMAINLESS FVIIA BY CATHEPSIN G-MEDIATED CLEAVAGE", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 306, no. 2 / 3, 20 July 1992 (1992-07-20), pages 157 - 160, XP000286918, ISSN: 0014-5793 *
PERSSON E ET PETERSON L C: "Structurally and functionally distinct Ca2+ binding sites in the gamma-carboxyglutamic acid-containing domain of factor VIIa", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, vol. 234, no. 1, 15 November 1995 (1995-11-15), pages 293 - 300, XP002101115, ISSN: 0014-2956 *

Also Published As

Publication number Publication date
WO2005044849A2 (en) 2005-05-19

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