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WO2005040818A3 - Diagnostics et traitements de maladies associees a un transporteur de cation organique flipt1 (flipt1) - Google Patents

Diagnostics et traitements de maladies associees a un transporteur de cation organique flipt1 (flipt1) Download PDF

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Publication number
WO2005040818A3
WO2005040818A3 PCT/EP2004/011012 EP2004011012W WO2005040818A3 WO 2005040818 A3 WO2005040818 A3 WO 2005040818A3 EP 2004011012 W EP2004011012 W EP 2004011012W WO 2005040818 A3 WO2005040818 A3 WO 2005040818A3
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
flipt1
therapeutics
diagnostics
diseases associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/011012
Other languages
English (en)
Other versions
WO2005040818A2 (fr
Inventor
Stefan Golz
Ulf Brueggemeier
Andreas Geerts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of WO2005040818A2 publication Critical patent/WO2005040818A2/fr
Publication of WO2005040818A3 publication Critical patent/WO2005040818A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne un FLIPT1 humain associé à des maladies cardiovasculaires, à des maladies dermatologiques, à des maladies gastroentérologiques, à des inflammations, à des cancers, à des maladies hématologiques, à des maladies respiratoires, à des maladies neurologiques et à des maladies urologiques. L'invention concerne également des dosages destinés à identifier des composés utiles dans le traitement ou la prévention de maladies cardiovasculaires, de maladies dermatologiques, de maladies gastroentérologiques, d'inflammations, de cancers, de maladies hématologiques, de maladies respiratoires, de maladies neurologiques et de maladies urologiques. Cette invention concerne aussi des composés qui se lient et/ou activent ou inhibent l'activité de FLIPT1, ainsi que des compositions pharmaceutiques contenant ces composés.
PCT/EP2004/011012 2003-10-17 2004-10-02 Diagnostics et traitements de maladies associees a un transporteur de cation organique flipt1 (flipt1) Ceased WO2005040818A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03023813.3 2003-10-17
EP03023813 2003-10-17

Publications (2)

Publication Number Publication Date
WO2005040818A2 WO2005040818A2 (fr) 2005-05-06
WO2005040818A3 true WO2005040818A3 (fr) 2005-06-09

Family

ID=34486080

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/011012 Ceased WO2005040818A2 (fr) 2003-10-17 2004-10-02 Diagnostics et traitements de maladies associees a un transporteur de cation organique flipt1 (flipt1)

Country Status (1)

Country Link
WO (1) WO2005040818A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083712A2 (fr) * 2001-04-12 2002-10-24 Incyte Genomics, Inc. Transporteurs et canaux ioniques
WO2002097095A1 (fr) * 2001-05-25 2002-12-05 Lexicon Genetics Incorporated Nouvelles proteines transporteuses humaines et polynucleotides les codant
US20030166880A1 (en) * 2000-11-21 2003-09-04 Millennium Pharmaceuticals, Inc. 57304, a novel human organic cation transporter and uses thereof
WO2003087155A1 (fr) * 2002-04-12 2003-10-23 Takeda Chemical Industries, Ltd. Nouvelle proteine et son adn

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030166880A1 (en) * 2000-11-21 2003-09-04 Millennium Pharmaceuticals, Inc. 57304, a novel human organic cation transporter and uses thereof
WO2002083712A2 (fr) * 2001-04-12 2002-10-24 Incyte Genomics, Inc. Transporteurs et canaux ioniques
WO2002097095A1 (fr) * 2001-05-25 2002-12-05 Lexicon Genetics Incorporated Nouvelles proteines transporteuses humaines et polynucleotides les codant
WO2003087155A1 (fr) * 2002-04-12 2003-10-23 Takeda Chemical Industries, Ltd. Nouvelle proteine et son adn

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200377, Derwent World Patents Index; Class B04, AN 2003-833710, XP002314877 *
ERALY SATISH A ET AL: "Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 297, no. 5, 11 October 2002 (2002-10-11), pages 1159 - 1166, XP002314876 *
ERALY SATISH A ET AL: "Organic anion and cation transporters occur in pairs of similar and similarly expressed genes.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 300, no. 2, 10 January 2003 (2003-01-10), pages 333 - 342, XP002314875 *

Also Published As

Publication number Publication date
WO2005040818A2 (fr) 2005-05-06

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