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WO2004110399A3 - Solvates of cefprozil - Google Patents

Solvates of cefprozil Download PDF

Info

Publication number
WO2004110399A3
WO2004110399A3 PCT/IB2004/002040 IB2004002040W WO2004110399A3 WO 2004110399 A3 WO2004110399 A3 WO 2004110399A3 IB 2004002040 W IB2004002040 W IB 2004002040W WO 2004110399 A3 WO2004110399 A3 WO 2004110399A3
Authority
WO
WIPO (PCT)
Prior art keywords
cefprozil
solvates
crystalline
relates
methylpyrrolidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2004/002040
Other languages
French (fr)
Other versions
WO2004110399A2 (en
Inventor
Yatendra Kumar
Neera Tewari
Shailendra Kumar Singh
Bishwa Prakash Rai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Priority to EP04737046A priority Critical patent/EP1638520A2/en
Publication of WO2004110399A2 publication Critical patent/WO2004110399A2/en
Publication of WO2004110399A3 publication Critical patent/WO2004110399A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to N-methylpyrrolidone and N,N-dimethylacetamide solvates of cefprozil. The invention also relates to processes for preparing the solvates of cefprozil, crystalline cefprozil from said solvates and pharmaceutical compositions that include the crystalline cefprozil.
PCT/IB2004/002040 2003-06-19 2004-06-18 Solvates of cefprozil Ceased WO2004110399A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04737046A EP1638520A2 (en) 2003-06-19 2004-06-18 Solvates of cefprozil

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN818/DEL/2003 2003-06-19
IN818DE2003 2003-06-19

Publications (2)

Publication Number Publication Date
WO2004110399A2 WO2004110399A2 (en) 2004-12-23
WO2004110399A3 true WO2004110399A3 (en) 2005-02-17

Family

ID=33548812

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/002040 Ceased WO2004110399A2 (en) 2003-06-19 2004-06-18 Solvates of cefprozil

Country Status (2)

Country Link
EP (1) EP1638520A2 (en)
WO (1) WO2004110399A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102344458B (en) * 2011-09-06 2013-10-16 山东罗欣药业股份有限公司 Cefprozil compound crystal and medicinal composition thereof
CN103524533B (en) * 2013-10-10 2016-01-27 珠海金鸿药业股份有限公司 A kind of cefprozil compound, its dispersible tablet, dry suspensoid and preparation method
CN110954392A (en) * 2019-12-26 2020-04-03 广药白云山化学制药(珠海)有限公司 Method for detecting enzyme protein residue in cefprozil prepared by enzyme method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
WO2003011871A2 (en) * 2001-08-01 2003-02-13 Sandoz Gmbh Intermediates in cephalosporin production
WO2003047590A1 (en) * 2001-11-30 2003-06-12 Phoenix Scientific, Inc. Antibiotic formulation and a method of making this formulation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
WO2003011871A2 (en) * 2001-08-01 2003-02-13 Sandoz Gmbh Intermediates in cephalosporin production
WO2003047590A1 (en) * 2001-11-30 2003-06-12 Phoenix Scientific, Inc. Antibiotic formulation and a method of making this formulation

Also Published As

Publication number Publication date
WO2004110399A2 (en) 2004-12-23
EP1638520A2 (en) 2006-03-29

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