[go: up one dir, main page]

WO2004108061A3 - Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament - Google Patents

Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament Download PDF

Info

Publication number
WO2004108061A3
WO2004108061A3 PCT/BR2004/000085 BR2004000085W WO2004108061A3 WO 2004108061 A3 WO2004108061 A3 WO 2004108061A3 BR 2004000085 W BR2004000085 W BR 2004000085W WO 2004108061 A3 WO2004108061 A3 WO 2004108061A3
Authority
WO
WIPO (PCT)
Prior art keywords
thiopental
medicament
pharmaceutical composition
producing
aqueous solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BR2004/000085
Other languages
French (fr)
Other versions
WO2004108061A2 (en
Inventor
Ogari Pacheco
Elisa Russo
Valter Russo
Jose Antonio Martins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Original Assignee
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cristalia Produtos Quimicos e Farmaceuticos Ltda filed Critical Cristalia Produtos Quimicos e Farmaceuticos Ltda
Publication of WO2004108061A2 publication Critical patent/WO2004108061A2/en
Publication of WO2004108061A3 publication Critical patent/WO2004108061A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention describes an injectable and stable pharmaceutical composition of thiopental ready-to-use, whose can be packed in glass ampoules for single doses or multidose vials for multiple doses. A method for stabilizing an aqueous solution of thiopental and, the use of thiopental to make a medicament are also described.
PCT/BR2004/000085 2003-06-10 2004-06-08 Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament Ceased WO2004108061A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR0301731-1A BR0301731A (en) 2003-06-10 2003-06-10 Injectable and stable thiopental pharmaceutical composition; method for stabilizing aqueous thiopental solutions, and using thiopental to produce a medicament
BRPI0301731-1 2003-06-10

Publications (2)

Publication Number Publication Date
WO2004108061A2 WO2004108061A2 (en) 2004-12-16
WO2004108061A3 true WO2004108061A3 (en) 2005-04-14

Family

ID=33494557

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2004/000085 Ceased WO2004108061A2 (en) 2003-06-10 2004-06-08 Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament

Country Status (2)

Country Link
BR (1) BR0301731A (en)
WO (1) WO2004108061A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020102215A1 (en) * 1996-10-28 2002-08-01 Nycomed Imaging As Diagnostic/therapeutic agents
US20030078300A1 (en) * 2001-04-19 2003-04-24 Pfizer Inc. Fused bicyclic or tricyclic amino acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020102215A1 (en) * 1996-10-28 2002-08-01 Nycomed Imaging As Diagnostic/therapeutic agents
US20030078300A1 (en) * 2001-04-19 2003-04-24 Pfizer Inc. Fused bicyclic or tricyclic amino acids

Also Published As

Publication number Publication date
BR0301731A (en) 2005-06-28
WO2004108061A2 (en) 2004-12-16

Similar Documents

Publication Publication Date Title
DE60236541D1 (en) INHIBITORS OF 11-BETA-HYDROXYSTEROIDDEHYDROGENASE TYPE 1
NO20051372L (en) injectable pharmaceutical suspension in a two-chamber vial
BR0210537A (en) Crystalline anticholinergic, process for its preparation and its application for the preparation of a medicine
EA200970726A1 (en) SOLID PREPARATION CONTAINING ALOGLYPTIN AND PIOGLITAZONE
BR0207726A (en) Pharmaceutical Salts
EP1728791A4 (en) Composition for solid pharmaceutical preparation of solifenacin or salt thereof
WO2001089571A3 (en) Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
WO2006117240A3 (en) Novel method for preventing or treating m tuberculosis infection
WO2003018059A3 (en) Combination preparations of aryl substituted propanolamine derivatives with other active ingredients and the use thereof
WO2004078105A3 (en) Fondaparinux sodium composition of high purity, method for production of said composition and pharmaceutical compositions containing the same as active ingredient
WO2007133751A3 (en) Base-stabilized polyorthoester formulations
ATE544445T1 (en) PRODUCTION OF STERILE AQUEOUS SUSPENSIONS WITH MICRONIZED CRYSTALLINE ACTIVE INGREDIENTS FOR INHALATION
ATE419842T1 (en) DELIVERY VEHICLES WITH NANOPARTICLES
BR122019018186B8 (en) enantiomerically pure (2s)-dotap chloride, its use, and pharmaceutical composition
NO20055766L (en) Positive modulators of nicotine acetylcholine receptors
ATE367165T1 (en) REEPITHELIALIZING PHARMACEUTICAL PREPARATIONS CONTAINING XANTHANG GUM
SE9904421D0 (en) New compounds
BR0013106A (en) Floating pharmaceutical composition, tablet, and tablet preparation process.
DE69904727D1 (en) INJECTABLE MEDICAMENT BASED ON A PHARMACEUTICALLY COMPATIBLE SALT OF CLOPIDOGREL BZW. OF TICLOPIDINE
EP1682565A4 (en) Iap nucleobase oligomers and oligomeric complexes and uses thereof
WO2006042478A8 (en) Small-molecule inhibitors of coronaviral main protease, their preparation and use
WO2004108061A3 (en) Stable injectable pharmaceutical composition of thiopental; method for stabilizing aqueous solutions of thiopental and, use of thiopental for producing a medicament
SE0101978D0 (en) New compounds
IT1313553B1 (en) OPTIMIZED FORMULATIONS CONSTITUTED BY SOLUTIONS OF STEROIDS GIVEN BY INHALATION.
NO20065898L (en) 1-heterocyclyl-1,5-dihydro-pyrido [3,2-b] indole-2-ones

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
122 Ep: pct application non-entry in european phase