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WO2004106936A3 - Agents diagnostiques et therapeutiques destines a des maladies associees au purinorecepteur p2y9 couple aux proteines g - Google Patents

Agents diagnostiques et therapeutiques destines a des maladies associees au purinorecepteur p2y9 couple aux proteines g Download PDF

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Publication number
WO2004106936A3
WO2004106936A3 PCT/EP2004/005554 EP2004005554W WO2004106936A3 WO 2004106936 A3 WO2004106936 A3 WO 2004106936A3 EP 2004005554 W EP2004005554 W EP 2004005554W WO 2004106936 A3 WO2004106936 A3 WO 2004106936A3
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
purinoreceptor
therapeutics
diagnostics
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/005554
Other languages
English (en)
Other versions
WO2004106936A2 (fr
Inventor
Stefan Golz
Ulf Brueggemeier
Andreas Geerts
Ralf Thiele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of WO2004106936A2 publication Critical patent/WO2004106936A2/fr
Publication of WO2004106936A3 publication Critical patent/WO2004106936A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un purinorécepteur P2Y9 humain associé à des troubles cancéreux, des troubles hématologiques, des maladies inflammatoires, des maladies neurologiques, des maladies cardiovasculaires et des maladies urologiques. L'invention concerne également des dosages destinés à l'identification de composés servant au traitement et à la prévention de troubles cancéreux, de troubles hématologiques, de maladies inflammatoires, de maladies neurologiques, de maladies cardiovasculaires et de maladies urologiques. L'invention concerne également des composés se liant à et/ou activant ou inhibant l'activité de P2Y9, ainsi que des compositions pharmaceutiques contenant de tels composés.
PCT/EP2004/005554 2003-06-02 2004-05-24 Agents diagnostiques et therapeutiques destines a des maladies associees au purinorecepteur p2y9 couple aux proteines g Ceased WO2004106936A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03012496 2003-06-02
EP03012496.0 2003-06-02

Publications (2)

Publication Number Publication Date
WO2004106936A2 WO2004106936A2 (fr) 2004-12-09
WO2004106936A3 true WO2004106936A3 (fr) 2005-06-16

Family

ID=33483902

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/005554 Ceased WO2004106936A2 (fr) 2003-06-02 2004-05-24 Agents diagnostiques et therapeutiques destines a des maladies associees au purinorecepteur p2y9 couple aux proteines g

Country Status (1)

Country Link
WO (1) WO2004106936A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0520405D0 (en) * 2005-10-07 2005-11-16 Imp College Innovations Ltd Biological agents and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0853126A2 (fr) * 1997-01-10 1998-07-15 Smithkline Beecham Corporation Clone HE8C54q de cADN codant pour un récepteur 7-transmembranaire humain
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
WO2002068591A2 (fr) * 2001-02-23 2002-09-06 Bristol-Myers Squibb Company Acides nucleiques du recepteur complexe a la proteine g, polypeptides, anticorps et leurs utilisations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0853126A2 (fr) * 1997-01-10 1998-07-15 Smithkline Beecham Corporation Clone HE8C54q de cADN codant pour un récepteur 7-transmembranaire humain
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
WO2002068591A2 (fr) * 2001-02-23 2002-09-06 Bristol-Myers Squibb Company Acides nucleiques du recepteur complexe a la proteine g, polypeptides, anticorps et leurs utilisations

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JANSSENS R ET AL: "Cloning of a human heptahelical receptor closely related to the P2Y5 receptor", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 236, 9 July 1997 (1997-07-09), pages 106 - 112, XP002124833, ISSN: 0006-291X *
O'DOWD B F ET AL: "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 187, no. 1, 10 March 1997 (1997-03-10), pages 75 - 81, XP004093242, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
WO2004106936A2 (fr) 2004-12-09

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