[go: up one dir, main page]

WO2004106322A3 - Polymorphes d'aripiprazole - Google Patents

Polymorphes d'aripiprazole Download PDF

Info

Publication number
WO2004106322A3
WO2004106322A3 PCT/IN2004/000113 IN2004000113W WO2004106322A3 WO 2004106322 A3 WO2004106322 A3 WO 2004106322A3 IN 2004000113 W IN2004000113 W IN 2004000113W WO 2004106322 A3 WO2004106322 A3 WO 2004106322A3
Authority
WO
WIPO (PCT)
Prior art keywords
aripiprazole
polymorphs
preparation
pharmaceutical compositions
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2004/000113
Other languages
English (en)
Other versions
WO2004106322A2 (fr
Inventor
Braj Bhushan Lohray
Vidya Bhushan Lohray
Kaushik Babubhai Sata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Priority to US10/554,366 priority Critical patent/US20060270683A1/en
Priority to EP04770647A priority patent/EP1618103A2/fr
Publication of WO2004106322A2 publication Critical patent/WO2004106322A2/fr
Publication of WO2004106322A3 publication Critical patent/WO2004106322A3/fr
Priority to NO20054762A priority patent/NO20054762L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouveaux polymorphes d'aripiprazole, leur procédé de préparation, des compositions pharmaceutiques les renfermant et leur utilisation.
PCT/IN2004/000113 2003-04-25 2004-04-22 Polymorphes d'aripiprazole Ceased WO2004106322A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/554,366 US20060270683A1 (en) 2003-04-25 2004-04-22 Polymorphs of aripiprazole
EP04770647A EP1618103A2 (fr) 2003-04-25 2004-04-22 Polymorphes d'aripiprazole
NO20054762A NO20054762L (no) 2003-04-25 2005-10-17 Polymorphs of aripiprazole

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN412/MUM/2003 2003-04-25
IN412MU2003 2003-04-25
IN583/MUM/2003 2003-06-06
IN583MU2003 2003-06-06

Publications (2)

Publication Number Publication Date
WO2004106322A2 WO2004106322A2 (fr) 2004-12-09
WO2004106322A3 true WO2004106322A3 (fr) 2005-04-21

Family

ID=33492303

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000113 Ceased WO2004106322A2 (fr) 2003-04-25 2004-04-22 Polymorphes d'aripiprazole

Country Status (4)

Country Link
US (1) US20060270683A1 (fr)
EP (1) EP1618103A2 (fr)
NO (1) NO20054762L (fr)
WO (1) WO2004106322A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5546717B2 (ja) * 2003-12-16 2014-07-09 テバ ファーマシューティカル インダストリーズ リミティド アリピプラゾール結晶質形態を調製する方法
US7714129B2 (en) 2003-12-16 2010-05-11 Teva Pharmaceutical Industries Ltd. Methods of preparing anhydrous aripiprazole form II
MXPA06008829A (es) 2004-02-05 2007-04-25 Teva Pharma Metodo de fabricar 7-(4-bromobutoxi)-3,4-dihidrocarboestirilo.
US7507823B2 (en) 2004-05-06 2009-03-24 Bristol-Myers Squibb Company Process of making aripiprazole particles
CN102627603A (zh) * 2004-11-18 2012-08-08 斯索恩有限公司 制备结晶阿立哌唑的方法
EP1686126A1 (fr) * 2005-01-27 2006-08-02 Sandoz AG Sel d'aripiprazole
EP1844036B1 (fr) * 2005-01-27 2015-09-23 Sandoz Ag Procédé de préparation de aripiprazole
EP1858514B1 (fr) * 2005-03-17 2014-11-26 Synthon B.V. Comprimes pharmaceutiques de forme cristalline d'aripiprazole ii
CA2600541C (fr) * 2005-03-17 2018-01-09 Synthon B.V. Procede de fabrication d'un aripiprazole type ii cristallin
EP1879865A1 (fr) * 2005-04-15 2008-01-23 Medichem S.A. Syntheses et preparations de polymorphes d'aripiprazole cristallin
HUP0500683A3 (en) * 2005-07-14 2009-03-30 Egis Gyogyszergyar Nyilvanosan New arylpiprazole salts for producing pharmaceutical composition
BRPI0608185A2 (pt) * 2005-12-22 2009-11-17 Teva Pharma processo para redução do tamanho de partìcula de aripiprazol
EP1808164B2 (fr) * 2006-01-05 2018-07-04 Teva Pharmaceutical Industries Ltd Méthode de granulation humide pour préparer des compositions pharmaceutiques d'aripiprazole
EP1808165B1 (fr) * 2006-01-05 2009-04-29 Teva Pharmaceutical Industries Ltd Formulations sèches d'aripiprazole
EP1880714A1 (fr) 2006-07-20 2008-01-23 Helm AG Aripiprazole amorphe et son procédé de préparation
US7799790B2 (en) 2006-07-20 2010-09-21 Helm Ag Amorphous aripiprazole and process for the preparation thereof
WO2008020453A2 (fr) * 2006-08-17 2008-02-21 Unichem Laboratories Limited Procédé pour la préparation d'un nouveau polymorphe cristallin de l'aripiprazole
PT2082735E (pt) 2008-01-23 2010-10-12 Helm Ag Aripripazole amorfo e processo para a sua preparação
EP2238976B1 (fr) 2009-04-03 2012-06-27 Hexal AG Films oraux comportant une base 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro- 1H-quinolin-2-one ou sels ou hydrates associés
WO2012003418A2 (fr) * 2010-07-02 2012-01-05 The University Of North Carolina At Chapel Hill Ligands fonctionnellement sélectifs des récepteurs d2 de dopamine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003026659A1 (fr) * 2001-09-25 2003-04-03 Otsuka Pharmaceutical Co., Ltd. Substance pharmaceutique d'aripiprazole faiblement hygroscopique et methodes de preparation associees

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003026659A1 (fr) * 2001-09-25 2003-04-03 Otsuka Pharmaceutical Co., Ltd. Substance pharmaceutique d'aripiprazole faiblement hygroscopique et methodes de preparation associees

Also Published As

Publication number Publication date
WO2004106322A2 (fr) 2004-12-09
NO20054762D0 (no) 2005-10-17
US20060270683A1 (en) 2006-11-30
NO20054762L (no) 2006-01-24
EP1618103A2 (fr) 2006-01-25

Similar Documents

Publication Publication Date Title
WO2004106322A3 (fr) Polymorphes d'aripiprazole
WO2004074244A3 (fr) Composes de pyrimidine
TW200505837A (en) Novel compounds
TW200519075A (en) Novel compounds
MXPA05012026A (es) Compuestos de azaindol como inhibidores de cinasa.
TW200612892A (en) Novel compounds
WO2005058835A3 (fr) Procedes de preparation de formes cristallines d'aripiprazole
MY134136A (en) Novel compounds comprising jak3 kinase inhibitors
WO2005046603A3 (fr) Composes pyridiniques
MXPA05012025A (es) Imidazo y tiazolopiridinas como inhibidores de cinasa jak3.
WO2004112719A8 (fr) Composes chimiques
WO2003095455A3 (fr) Composes therapeutiques
ZA200403682B (en) N-adamantylmethyl derivatives and intermediates as pharmaceutical composition and processes for their preparation.
WO2004093800A3 (fr) Derives de thyronamine et analogues et des methodes d'utilisation de ces composes
WO2007093880A3 (fr) Nouveaux dérivés d'indolopyrone et leur procédé de préparation
TW200630336A (en) Novel compounds
TW200508197A (en) Indolone-acetamide derivatives, processes for preparing them and their uses
TW200621690A (en) Novel compounds
IL160171A0 (en) Depsipeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
WO2005063764A3 (fr) Nouveaux pyrrolocarbazoles fusionnes
HUP0401522A2 (en) New 4-benzylidene-piperidine derivatives, pharmaceutical compositions containing the same and process for their preparation
ZA200506422B (en) Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use of the same as medicaments, and medicament containing such compounds
WO2004105773A3 (fr) Utilisation de s1p
PT1625116E (pt) Processo para a preparação de derivados de carboestirilo, tais como aripiprazole e seus intermediários
WO2005055943A3 (fr) Derives de la vinorelbine

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2004770647

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2004770647

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2006270683

Country of ref document: US

Ref document number: 10554366

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10554366

Country of ref document: US