WO2004030634A3 - Therapeutic compositions - Google Patents
Therapeutic compositions Download PDFInfo
- Publication number
- WO2004030634A3 WO2004030634A3 PCT/US2003/031717 US0331717W WO2004030634A3 WO 2004030634 A3 WO2004030634 A3 WO 2004030634A3 US 0331717 W US0331717 W US 0331717W WO 2004030634 A3 WO2004030634 A3 WO 2004030634A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- therapeutic compositions
- therapeutic
- enclosed
- making
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Therapeutic siRNAs and methods of making and using are enclosed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003282722A AU2003282722A1 (en) | 2002-10-02 | 2003-10-02 | Therapeutic compositions |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41569802P | 2002-10-02 | 2002-10-02 | |
| US60/415,698 | 2002-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004030634A2 WO2004030634A2 (en) | 2004-04-15 |
| WO2004030634A3 true WO2004030634A3 (en) | 2004-09-23 |
Family
ID=32069900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2003/031717 Ceased WO2004030634A2 (en) | 2002-10-02 | 2003-10-02 | Therapeutic compositions |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003282722A1 (en) |
| WO (1) | WO2004030634A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8188060B2 (en) | 2008-02-11 | 2012-05-29 | Dharmacon, Inc. | Duplex oligonucleotides with enhanced functionality in gene regulation |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005003788A1 (en) * | 2005-01-19 | 2006-07-20 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | siRNA molecules for the treatment of blood vessels |
| KR101141544B1 (en) | 2009-03-13 | 2012-05-03 | 한국과학기술원 | Multi-conjugate of siRNA and preparing method thereof |
| WO2010141511A2 (en) | 2009-06-01 | 2010-12-09 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotides for multivalent rna interference, compositions and methods of use thereof |
| IL316159A (en) | 2015-06-15 | 2024-12-01 | Mpeg La Llc | Oligonucleotides with a defined number of polymers and methods of their preparation |
| WO2017035278A1 (en) | 2015-08-24 | 2017-03-02 | Halo-Bio Rnai Therapeutics, Inc. | Polynucleotide nanoparticles for the modulation of gene expression and uses thereof |
| SG11201906728TA (en) | 2017-02-06 | 2019-08-27 | Mpeg La Llc | Multimeric oligonucleotides having decreased kidney clearance |
| CA3232968A1 (en) | 2021-10-14 | 2023-04-20 | Jasper Williams | Immune cells having co-expressed shrnas and logic gate systems |
| CN120112638A (en) | 2022-09-13 | 2025-06-06 | 阿森纳生物科学公司 | Immune cells with co-expressed TGFBR shRNA |
| CN119968464A (en) | 2022-09-16 | 2025-05-09 | 阿森纳生物科学公司 | Immune cells with combinatorial genetic perturbations |
| TW202442689A (en) | 2023-03-03 | 2024-11-01 | 美商亞森諾生物科學公司 | Systems targeting psma and ca9 |
| US20250297255A1 (en) | 2024-03-20 | 2025-09-25 | Arsenal Biosciences, Inc. | Systems targeting tmprss4 and slc34a2 |
-
2003
- 2003-10-02 WO PCT/US2003/031717 patent/WO2004030634A2/en not_active Ceased
- 2003-10-02 AU AU2003282722A patent/AU2003282722A1/en not_active Abandoned
Non-Patent Citations (5)
| Title |
|---|
| ELBASHIR ET AL: "RNA interference is mediated by 21- and 22-nucleotide RNAs", GENES AND DEVELOPMENT, vol. 15, 2001, pages 188 - 200, XP002206453 * |
| FIRE ET AL: "Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans", NATURE, vol. 391, 19 February 1998 (1998-02-19), pages 806 - 811, XP002977033 * |
| PAUL ET AL: "Effective expression of small interfering RNA in human cells", NATURE BIOTECHNOLOGY, vol. 29, May 2002 (2002-05-01), pages 505 - 508, XP001121066 * |
| SUI ET AL: "A DNA vector-based RNAi technology to suppress gene expression in mammalian cells", PNAS, vol. 99, no. 8, 16 April 2002 (2002-04-16), pages 5515 - 5520, XP002964701 * |
| TUSCHL ET AL: "Targeted mRNA degradation by double-stranded RNA in vitro", GENES AND DEVELOPMENT, vol. 13, 1999, pages 3191 - 3197, XP002945265 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8188060B2 (en) | 2008-02-11 | 2012-05-29 | Dharmacon, Inc. | Duplex oligonucleotides with enhanced functionality in gene regulation |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003282722A1 (en) | 2004-04-23 |
| WO2004030634A2 (en) | 2004-04-15 |
| AU2003282722A8 (en) | 2004-04-23 |
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