[go: up one dir, main page]

WO2004024235A1 - Irm dans un appareil de radiotherapie guidee avec compensateurs d'heterogeneite de faisceau - Google Patents

Irm dans un appareil de radiotherapie guidee avec compensateurs d'heterogeneite de faisceau Download PDF

Info

Publication number
WO2004024235A1
WO2004024235A1 PCT/IB2003/004472 IB0304472W WO2004024235A1 WO 2004024235 A1 WO2004024235 A1 WO 2004024235A1 IB 0304472 W IB0304472 W IB 0304472W WO 2004024235 A1 WO2004024235 A1 WO 2004024235A1
Authority
WO
WIPO (PCT)
Prior art keywords
radiation therapy
therapy apparatus
mri
linear accelerator
imaging device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2003/004472
Other languages
English (en)
Inventor
Jan Jacob Wouter Lagendijk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elekta AB
Original Assignee
Elekta AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elekta AB filed Critical Elekta AB
Priority to AU2003274393A priority Critical patent/AU2003274393A1/en
Publication of WO2004024235A1 publication Critical patent/WO2004024235A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/381—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1055—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]

Definitions

  • This invention relates to improvements in radiotherapy techniques and position verification in radiotherapy.
  • the invention relates to the use of Magnetic Resonance Imaging (MRI) in radiotherapy and position verification.
  • MRI Magnetic Resonance Imaging
  • Existing radiotherapy treatments are commonly carried out by means of a linear accelerator which bombards cancerous tissues with high energy X-rays or electron beams to inhibit growth and spreading of the malignant tissues.
  • An essential parameter monitored in existing radiotherapy treatments is the exact daily position and extension of the target volume of tissue, including variations in position and size both during the treatment session and throughout the whole treatment course. Tumour control probability analyses indicate that dose escalation, which can be performed in case of an exactly known tumour position, may greatly enhance tumour control.
  • the positioning problems can be solved with invasive radio opaque markers inside the tumour, which are visible on amorphous silicon flat panel megavoltage imaging.
  • invasive radio opaque markers inside the tumour, which are visible on amorphous silicon flat panel megavoltage imaging.
  • markers gold seeds of 1.0 mm diameter and 5 mm length used for prostate position verification as reported by Nederveen et al in Phys. Med. Biol. 46(4), 2001, 1219-30.
  • CT computed to position verification
  • Major disadvantages of the use of integrated CT for daily radiotherapy position verification are the inherent slow data acquisition (gantry rotation), the inferior soft-tissue visibility and the 2D, transversal slide, imaging.
  • MRI is commonly used in the 3 dimensional imaging of soft tissues such as the brain and spinal cord to detect abnormalities without the need to expose the subject to harmful radiation such as X-rays.
  • Co-pending International Patent Application PCT/GB2002/03339 discloses a radiotherapy apparatus comprising a magnetic resonance imaging device integrated with a linear accelerator.
  • This invention aims to improve upon the concept described in PCT/GB2002/03339 and to provide an apparatus having improved properties over that disclosed therein.
  • the invention provides a radiotherapy apparatus comprising a magnetic resonance imaging device integrated with a linear accelerator wherein a B-field compensator means is associated with the magnetic resonance imaging device which, in use, adapts the B-field produced by the magnetic resonance imaging device in the vicinity of the linear accelerator thereby to minimise the influence of the B-field on the particles emitted by the accelerator.
  • a magnetic resonance imaging device typically comprises a large ring shaped magnet, typically comprised of electromagnetic coils wound on a core of magnetisable material. Where the coils are arranged closer to the inner surface of the ring, than the outer surface, the B-field (Bp (n ) at the centre of the magnet is substantially greater than that (Bp ou ) at the outer surface of the ring and directed in an opposing direction.
  • the B field of the unadapted magnet (Bp) can be compensated by the introduction of additional coils of opposing polarity. For example, these additional coils may be placed in alignment with one or more existing coils of the MRI at a position closer to the outer surface of the ring.
  • the result of these added coils is to create a compensation field (Be) at the outer and inner surfaces of the ring consisting of an outer field Bc o u t and an inner field Bc in .
  • the compensated field (BO) resulting from the adapted MRI is consequently composed of an outer field equal to Bp out - Bc out and an inner field equal to Bp in - Bc ln .
  • the compensated field BO can be controlled.
  • the coils are selected and positioned so as to produce an area of zero (or minimal) Tesla in the region about the MRI where the particle source of the linear accelerator is to be located.
  • the compensator means is selected and positioned such that the compensation field Bc out at the outer surface of the magnetic ring of the MRI is approximately equal, but oppositely directed to the field Bp out of the uncompensated magnetic ring providing an area of substantially zero Tesla in or near to which the particle source of a linear particle accelerator can be positioned.
  • the invention provides a radiotherapy apparatus comprising a magnetic resonance imaging device integrated with a linear accelerator wherein the particle source of the linear accelerator is positioned a fixed radial distance from the subject to be targeted and has associated therewith a compensation filter for compensating heterogeneity of the beam induced by the magnetic resonance imaging device, thereby to provide a substantially homogenous beam at the target to be treated.
  • This second aspect may be used in conjunction with the first aspect to provide an improved system, or it may be used independently thereof.
  • the inventors have recognised that the physical construction of an MRI can affect the beam quality of a linear accelerator.
  • the inventors have found that deterioration of beam quality can be corrected by suitable positioning of the accelerator and the introduction of a compensation filter.
  • a preferred arrangement has been found to comprise positioning the accelerator at a fixed radial position outside of the solenoid drum of an MRI and positioning a compensation filter in radial alignment with the accelerator, on an inner surface of the solenoid drum, that is adjacent the centre space reserved for receiving the target.
  • the characteristics of the compensation filter are defined by first measuring the heterogeneity induced in the accelerator beam by the structure of the MRI.
  • the filter is designed to introduce heterogeneity which, when added to the heterogeneity introduced by the active MRI, results in a substantially uniform radiation field.
  • the compensation filter may, optionally, be used in conjunction with intensity modulation techniques to further reduce the incidence of radiation scatter in the beam.
  • the gradient coils of the drum of the MRI may be split to provide a gap through which the beam emitted by the linear accelerator may pass.
  • This adaptation to a standard drum arrangement has been found to significantly reduce attenuation of the beam and result in a lower incidence of beam scattering. Furthermore it reduces the copper content of the gradient coils (for example by replacement of 3cm copper with 6cm epoxy, the latter of which provides a more homogeneous transmission of the linear accelerator beam) thus reducing the number of items to be compensated for by the compensation filter rendering the compensation task more simple.
  • This splitting of the gradient coils has been found to have no significant debilitatory affect on the performance of the MRI.
  • the rotatable gantry on which the accelerator is mounted is desirably configured to have a plurality of fixed locating positions for the accelerator all having a fixed radial distance from the target. Spaces in the gradient coils and compensation filters can then be positioned in the non-moving MRI to align with each of the fixed locating positions of the accelerator.
  • an odd number of fixed locating positions for the accelerator Preferably these positions are equally spaced apart about the circumference of the MRI. Preferred numbers of fixed locating positions are 7, 9 or 11. In a preferred embodiment, the number of fixed locations is 11 each spaced at an angle of about 33 degrees from the two adjacent positions.
  • the support structure of the MRI may optionally have material removed adjacent the fixed locating positions of the accelerator. This further simplifies the task for the compensation filter. It has been found that the size (including the radius of the gantry which carries the linear accelerator) and weight of the integrated system can be further reduced by removing material from the cryostat (for example from 4cm Aluminium to 2cm Aluminium).
  • Figure 1 illustrates schematically an open ring type embodiment of the invention
  • Figure 2 illustrates schematically a closed drum type embodiment of the invention
  • Figure 3 illustrates in further detail an embodiment of the type shown in Figure 2;
  • Figure 4 illustrates the B fields of a) a standard MRI as known from the prior art; b) a compensation field produced by compensations means in accordance with the second aspect of the invention; and c) the resultant field of an MRI compensated by compensation means in accordance with the invention;
  • Figure 5 illustrates an embodiment of the invention incorporating compensation means in the form of additional electromagnetic coils
  • Figure 6 illustrates the embodiment of Figure 5 further incorporating a compensation filter
  • Figure 7 illustrates the embodiment of Figure 5 further incorporating a split gradient coil
  • Figure 8 illustrates the embodiment of Figure 7 further incorporating gaps in the support structure.
  • an open ring arrangement comprises 3 rings 1, 2 and 3 arranged linearly along a common centre and slightly spaced apart.
  • a table 4 is arranged slightly below the centre line of the rings and in parallel therewith.
  • a subject 5 lies on the table 4, encircled by the rings 1,2 and 3 for treatment.
  • Rings 1 and 3 represent the MRI, whilst ring 2 incorporates the linear accelerator.
  • the table 4 is moveable linearly through the rings 1, 2 and 3 so that the subject tissue may be located, imaged (using the MRI) and treated (using the linear accelerator.
  • the MRI rings 1 and 3 create an imaging volume which encompasses the accelerator isocentre of ring 2.
  • FIG. 2 illustrates a closed drum arrangement of the invention.
  • the drum comprises two main portions, an outer portion 22 which incorporates the gantry on which the linear accelerator is mounted and an inner portion 21 incorporating the MRI.
  • a common bore 20 extends concentrically through the centre of the two cylindrical portions 23, 21.
  • a table 24 is positioned within the bore, slightly below the centre, and is slideable into and out of the bore 20.
  • Figure 3 shows a more detailed outline sketch of an embodiment of the form shown in Figure 2.
  • the arrangement comprises outer portion 32 which incorporates a linear accelerator having a head including an X-ray gun 39, tube 38 magnet 36 and focus 37.
  • the inner portion 31 of the drum consists of the MRI and surrounds a central bore 30, common to both the MRI and accelerator which share a common isocentre 41.
  • the line 40 indicates the typical floor level relative to the apparatus.
  • Figure 4a shows a primary field configuration for a drum 1 of a conventional drum type MRI.
  • the drum has a plurality of coils 2a, 2b, 2c, 2d encircling its isocentre and positioned towards the inner surface of the magnetic drum of the MRI.
  • the field has a component in an area surrounding the outer surface of the ring Bp out and a component passing through the centre of the drum Bpm.
  • the first component Bp out is relatively less strong than and in a direction opposing that of the second component Bp in .
  • Figure 4b shows the field produced by a drum of similar configuration to that of 4a) but equipped only with a pair of coils 2'e and 2'f positioned toward opposing faces of the drum and near the outer surface thereof.
  • the field has components Bc out which is of similar strength but in an opposing direction to Bp ou and Bc ln which is of significantly lower strength than Bp in and oppositely directed thereto.
  • Figure 4c illustrates the field pattern resulting when the fields of Figures 4a) and 4b) are combined in an MRI compensated in accordance with the first aspect of the invention.
  • the opposing, but substantially equal strength field components Bp out and Bc out cancel each other creating an area of substantially zero Tesla towards the central region of the outer surface of the ring.
  • FIG. 5 shows an embodiment of the invention in further detail.
  • the components of the MRI are further illustrated.
  • the MRI comprises a cryostat containing a support structure 3 onto which are mounted both the primary coils 2a, ...2d and the compensation coils 2'e to 2'f.
  • Positioned around the inner circumference of the drum 1 are gradient coils 6 and RF coils 5.
  • Positioned in the zero Tesla area (as shown in Figure 4c)) is a rotatable gantry 4 on which is mounted a linear accelerator 7.
  • the accelerator emits particles (for example X-rays or electrons) in a beam B to be targeted at a subject introduced into the central bore at the common isocentre of the gantry 4 and drum 1.
  • Figure 6 shows an embodiment broadly similar to that of Figure 5 but incorporating a compensation filter F in alignment with the linear accelerator 7 and the beam B. Whilst only a single filter is shown in the Figure it is to be understood that in practice, the system would be provided with a plurality of such filters positioned at fixed locations about the inner circumference of the drum so as to provide compensation at a plurality of fixed locations for the linear accelerator when the gantry is rotated about the isocentre of the system
  • Figure 7 shows an embodiment broadly similar to that of Figure 6 but incorporating split gradient coils.
  • the gradient coil is split into two substantially even sized portions with a gap between them.
  • the gap aligns with the linear accelerator 7 and the beam B such that the beam B can pass through the gap.
  • the filter F is located in the gap, behind the RF coil.
  • Figure 8 shows a further embodiment of the invention. This embodiment is broadly similar to that of Figure 7 but incorporates a split or perforated support structure 3. As can be seen, a gap or hole is provided in the support structure in radial alignment with the gap in the gradient coil, the compensation filter F and the linear accelerator 7 such that the beam B can pass therethrough.

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Pathology (AREA)
  • Electromagnetism (AREA)
  • Animal Behavior & Ethology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Radiation-Therapy Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

L'invention concerne un appareil de thérapie par rayonnement comprenant un dispositif d'imagerie par résonance magnétique intégré avec un accélérateur linéaire dans lequel des moyens de compensation de champ B sont associés au dispositif d'imagerie par résonance magnétique qui, à l'utilisation, adapte le champ B, produit par le dispositif d'imagerie par résonance magnétique, au voisinage de l'accélérateur ce qui permet de minimiser l'influence du champ B sur les particules émises par l'accélérateur.
PCT/IB2003/004472 2002-09-13 2003-09-02 Irm dans un appareil de radiotherapie guidee avec compensateurs d'heterogeneite de faisceau Ceased WO2004024235A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003274393A AU2003274393A1 (en) 2002-09-13 2003-09-02 Mri in guided radiotherapy apparatus with beam heterogeneity compensators

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0221174.6 2002-09-13
GB0221174A GB2393373A (en) 2002-09-13 2002-09-13 MRI in guided radiotherapy and position verification

Publications (1)

Publication Number Publication Date
WO2004024235A1 true WO2004024235A1 (fr) 2004-03-25

Family

ID=9943941

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2003/004472 Ceased WO2004024235A1 (fr) 2002-09-13 2003-09-02 Irm dans un appareil de radiotherapie guidee avec compensateurs d'heterogeneite de faisceau

Country Status (3)

Country Link
AU (1) AU2003274393A1 (fr)
GB (1) GB2393373A (fr)
WO (1) WO2004024235A1 (fr)

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006136864A1 (fr) * 2005-06-22 2006-12-28 Siemens Magnet Technology Ltd Équipement de thérapie par rayonnement particulaire
WO2007045076A1 (fr) * 2005-10-17 2007-04-26 Alberta Cancer Board Systeme d'irm et de radiotherapie externe integre
US7907987B2 (en) 2004-02-20 2011-03-15 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
CN102145206A (zh) * 2010-02-10 2011-08-10 西门子公司 具有磁共振装置和辐射治疗装置的组合的设备
US8073102B2 (en) 2005-10-17 2011-12-06 Alberta Health Services Real-time dose reconstruction using dynamic simulation and image guided adaptive radiotherapy
WO2012049466A1 (fr) * 2010-10-15 2012-04-19 Siemens Aktiengesellschaft Dispositif de déviation de faisceau dans une unité combinée de radiothérapie et de résonance magnétique
WO2012164527A1 (fr) * 2011-05-31 2012-12-06 Koninklijke Philips Electronics N.V. Correction du champ magnétique statique d'un dispositif d'irm de radiothérapie
WO2012176181A1 (fr) * 2011-06-23 2012-12-27 Koninklijke Philips Electronics N.V. Radiothérapie guidée par l'image
US20130044863A1 (en) * 2010-04-15 2013-02-21 Elekta Ab (Publ) Radiotherapy and Imaging Apparatus
CN103210318A (zh) * 2010-11-09 2013-07-17 皇家飞利浦电子股份有限公司 具有至少两个发射和接收信道的磁共振成像以及放射治疗设备
CN103260511A (zh) * 2010-12-08 2013-08-21 皇家飞利浦电子股份有限公司 滑环组件
EP2454617A4 (fr) * 2009-07-15 2013-11-20 Viewray Inc Procédé et appareil pour blinder un accélérateur linéaire et un dispositif d'imagerie par résonance magnétique l'un de l'autre
WO2014044635A1 (fr) * 2012-09-18 2014-03-27 Koninklijke Philips N.V. Linac guidé par résonance magnétique
US8710843B2 (en) 2010-04-27 2014-04-29 University Health Network Magnetic resonance imaging apparatus for use with radiotherapy
WO2014203190A1 (fr) * 2013-06-21 2014-12-24 Koninklijke Philips N.V. Système de cale destiné à un scanner hybride à résonance magnétique
US8983573B2 (en) 2008-06-24 2015-03-17 Alberta Health Services Radiation therapy system
CN105056406A (zh) * 2015-07-31 2015-11-18 北京健联医疗科技有限公司 紧凑型磁共振引导的粒子治疗设备
US9511242B2 (en) 2010-12-13 2016-12-06 Koninklijke Philips Electronics N.V. Therapeutic apparatus comprising a radiotherapy apparatus, a mechanical positioning system, and a magnetic resonance imaging system
US9606206B2 (en) 2008-06-25 2017-03-28 Koninklijke Philips Electronics N.V. Radiation therapy system with real time magnetic resonance monitoring
CN106621075A (zh) * 2016-12-22 2017-05-10 上海联影医疗科技有限公司 放射治疗装置
US9669238B2 (en) 2010-12-08 2017-06-06 Elekta Ab (Publ) Radiotherapeutic apparatus
US9966160B2 (en) 2015-11-24 2018-05-08 Viewray Technologies, Inc. Radiation beam collimating systems and methods
US10061000B2 (en) 2012-11-06 2018-08-28 Siemens Healthcare Limited MRI magnet for radiation and particle therapy
US10393836B2 (en) 2011-12-13 2019-08-27 Viewray Technologies, Inc. Active resistive shimming for MRI devices
US10413751B2 (en) 2016-03-02 2019-09-17 Viewray Technologies, Inc. Particle therapy with magnetic resonance imaging
US10463884B2 (en) 2013-03-15 2019-11-05 Viewray Technologies, Inc. Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging
US10561861B2 (en) 2012-05-02 2020-02-18 Viewray Technologies, Inc. Videographic display of real-time medical treatment
CN110988523A (zh) * 2019-11-18 2020-04-10 国网河北省电力有限公司电力科学研究院 一种电力变压器绕组变形累积效应的检测方法及装置
US10821303B2 (en) 2012-10-26 2020-11-03 Viewray Technologies, Inc. Assessment and improvement of treatment using imaging of physiological responses to radiation therapy
US11000706B2 (en) 2016-12-13 2021-05-11 Viewray Technologies, Inc. Radiation therapy systems and methods
US11033758B2 (en) 2017-12-06 2021-06-15 Viewray Technologies, Inc. Radiotherapy systems, methods and software
US11209509B2 (en) 2018-05-16 2021-12-28 Viewray Technologies, Inc. Resistive electromagnet systems and methods
US11378629B2 (en) 2016-06-22 2022-07-05 Viewray Technologies, Inc. Magnetic resonance imaging
US11426604B2 (en) 2016-08-08 2022-08-30 Koninklijke Philips N.V. Mock-up antenna and coil system

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7640052B2 (en) * 2004-05-28 2009-12-29 Ippp, Llc Method of integrated proton beam and therapeutic magnetic resonance therapy
GB2424281A (en) * 2005-03-17 2006-09-20 Elekta Ab Radiotherapeutic Apparatus with MRI
US9498167B2 (en) 2005-04-29 2016-11-22 Varian Medical Systems, Inc. System and methods for treating patients using radiation
GB2427478B (en) 2005-06-22 2008-02-20 Siemens Magnet Technology Ltd Particle radiation therapy equipment and method for simultaneous application of magnetic resonance imaging and particle radiation
US8487269B2 (en) 2007-02-28 2013-07-16 Siemens Aktiengesellschaft Combined radiation therapy and magnetic resonance unit
DE102008007245B4 (de) 2007-02-28 2010-10-14 Siemens Aktiengesellschaft Kombiniertes Strahlentherapie- und Magnetresonanzgerät
GB2513522A (en) * 2010-12-08 2014-11-05 Elekta Ab Radiotherapeutic apparatus
US9675271B2 (en) * 2013-03-13 2017-06-13 Viewray Technologies, Inc. Systems and methods for radiotherapy with magnetic resonance imaging
GB2545436B (en) * 2015-12-15 2018-04-11 Siemens Healthcare Ltd A cylindrical superconducting magnet with a shield of ferromagnetic material
EP3327457A1 (fr) * 2016-11-23 2018-05-30 Siemens Healthcare GmbH Imagerie médicale comprenant une unité magnétique et une unité de rayonnement
CN114796894B (zh) 2018-11-14 2025-03-25 上海联影医疗科技股份有限公司 放射治疗系统

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988866A (en) * 1987-07-21 1991-01-29 Westerlund Kjell B Measuring device for checking radiation fields from treatment machines for radiotherapy
WO1994029882A1 (fr) * 1993-06-09 1994-12-22 Wisconsin Alumni Research Foundation Appareil aplanisseur dynamique de faisceau pour la radiotherapie
US6198957B1 (en) * 1997-12-19 2001-03-06 Varian, Inc. Radiotherapy machine including magnetic resonance imaging system
WO2002007820A1 (fr) * 2000-07-22 2002-01-31 Koninklijke Philips Electronics N.V. Procede et appareil de programmation de therapie par resonance magnetique (mr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3856821B2 (ja) * 1994-06-30 2006-12-13 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Ｘ線装置を有する磁気共鳴装置
JP3703491B2 (ja) * 1994-11-24 2005-10-05 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Ｘ線装置を含む磁気共鳴装置
GB9520564D0 (en) * 1995-10-07 1995-12-13 Philips Electronics Nv Apparatus for treating a patient
US6725078B2 (en) * 2000-01-31 2004-04-20 St. Louis University System combining proton beam irradiation and magnetic resonance imaging
GB2382512A (en) * 2001-07-20 2003-05-28 Elekta Oncology Syst Ltd MRI in guided radiotherapy and position verification

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988866A (en) * 1987-07-21 1991-01-29 Westerlund Kjell B Measuring device for checking radiation fields from treatment machines for radiotherapy
WO1994029882A1 (fr) * 1993-06-09 1994-12-22 Wisconsin Alumni Research Foundation Appareil aplanisseur dynamique de faisceau pour la radiotherapie
US6198957B1 (en) * 1997-12-19 2001-03-06 Varian, Inc. Radiotherapy machine including magnetic resonance imaging system
WO2002007820A1 (fr) * 2000-07-22 2002-01-31 Koninklijke Philips Electronics N.V. Procede et appareil de programmation de therapie par resonance magnetique (mr)

Cited By (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7907987B2 (en) 2004-02-20 2011-03-15 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
US11497937B2 (en) 2004-02-20 2022-11-15 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
US8190233B2 (en) 2004-02-20 2012-05-29 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
US10688319B2 (en) 2004-02-20 2020-06-23 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
US8838202B2 (en) 2005-06-22 2014-09-16 Siemens Plc Particle radiation therapy equipment
WO2006136864A1 (fr) * 2005-06-22 2006-12-28 Siemens Magnet Technology Ltd Équipement de thérapie par rayonnement particulaire
WO2007045076A1 (fr) * 2005-10-17 2007-04-26 Alberta Cancer Board Systeme d'irm et de radiotherapie externe integre
CN103272337B (zh) * 2005-10-17 2016-03-30 艾伯塔健康服务中心 集成的体外射束放射治疗和mri系统
US8958528B2 (en) 2005-10-17 2015-02-17 Alberta Health Services Real-time dose reconstruction using dynamic simulation and image guided adaptive radiotherapy
US8073102B2 (en) 2005-10-17 2011-12-06 Alberta Health Services Real-time dose reconstruction using dynamic simulation and image guided adaptive radiotherapy
CN103272337A (zh) * 2005-10-17 2013-09-04 艾伯塔健康服务中心 集成的体外射束放射治疗和mri系统
US9468777B2 (en) 2005-10-17 2016-10-18 Alberta Health Services Integrated external beam radiotherapy and MRI system
US8983573B2 (en) 2008-06-24 2015-03-17 Alberta Health Services Radiation therapy system
US9606206B2 (en) 2008-06-25 2017-03-28 Koninklijke Philips Electronics N.V. Radiation therapy system with real time magnetic resonance monitoring
US10463883B2 (en) 2009-07-15 2019-11-05 Viewray Technologies, Inc. Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
US12105166B2 (en) 2009-07-15 2024-10-01 Viewray Systems, Inc. Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
EP2454617A4 (fr) * 2009-07-15 2013-11-20 Viewray Inc Procédé et appareil pour blinder un accélérateur linéaire et un dispositif d'imagerie par résonance magnétique l'un de l'autre
US10918887B2 (en) 2009-07-15 2021-02-16 Viewray Technologies, Inc. Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
US9421398B2 (en) 2009-07-15 2016-08-23 Viewray Technologies, Inc. Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
US8836332B2 (en) 2009-07-15 2014-09-16 Viewray Incorporated Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
US11452463B2 (en) 2009-07-15 2022-09-27 Viewray Technologies, Inc. Method and apparatus for shielding a linear accelerator and a magnetic resonance imaging device from each other
CN102145206B (zh) * 2010-02-10 2015-09-16 西门子公司 具有磁共振装置和辐射治疗装置的组合的设备
EP2353647A1 (fr) * 2010-02-10 2011-08-10 Siemens Aktiengesellschaft Dispositif doté d'une combinaison à partir d'un dispositif à résonance magnétique et d'un dispositif de thérapie par rayonnement
CN102145206A (zh) * 2010-02-10 2011-08-10 西门子公司 具有磁共振装置和辐射治疗装置的组合的设备
US20130044863A1 (en) * 2010-04-15 2013-02-21 Elekta Ab (Publ) Radiotherapy and Imaging Apparatus
US8710843B2 (en) 2010-04-27 2014-04-29 University Health Network Magnetic resonance imaging apparatus for use with radiotherapy
US8903471B2 (en) 2010-10-15 2014-12-02 Siemens Aktiengesellschaft Beam deflection arrangement within a combined radiation therapy and magnetic resonance unit
WO2012049466A1 (fr) * 2010-10-15 2012-04-19 Siemens Aktiengesellschaft Dispositif de déviation de faisceau dans une unité combinée de radiothérapie et de résonance magnétique
US11116418B2 (en) 2010-11-09 2021-09-14 Koninklijke Philips N.V. Magnetic resonance imaging and radiotherapy apparatus with at least two-transmit-and receive channels
CN103210318A (zh) * 2010-11-09 2013-07-17 皇家飞利浦电子股份有限公司 具有至少两个发射和接收信道的磁共振成像以及放射治疗设备
US9669238B2 (en) 2010-12-08 2017-06-06 Elekta Ab (Publ) Radiotherapeutic apparatus
CN103260511B (zh) * 2010-12-08 2015-12-16 皇家飞利浦电子股份有限公司 滑环组件
CN103260511A (zh) * 2010-12-08 2013-08-21 皇家飞利浦电子股份有限公司 滑环组件
US9511242B2 (en) 2010-12-13 2016-12-06 Koninklijke Philips Electronics N.V. Therapeutic apparatus comprising a radiotherapy apparatus, a mechanical positioning system, and a magnetic resonance imaging system
US20140084926A1 (en) * 2011-05-31 2014-03-27 Koninklijke Philips N.V. Correcting the static magnetic field of an mri radiotherapy apparatus
US9664763B2 (en) 2011-05-31 2017-05-30 Koninklijke Philips N.V. Correcting the static magnetic field of an MRI radiotherapy apparatus
WO2012164527A1 (fr) * 2011-05-31 2012-12-06 Koninklijke Philips Electronics N.V. Correction du champ magnétique statique d'un dispositif d'irm de radiothérapie
US10132897B2 (en) 2011-05-31 2018-11-20 Koninklijke Philips N.V. Correcting the magnetic field of a medical apparatus with a gantry
US20180003789A1 (en) * 2011-05-31 2018-01-04 Koninklijke Philips N.V. Correcting the magnetic field of a medical apparatus with a gantry
WO2012176181A1 (fr) * 2011-06-23 2012-12-27 Koninklijke Philips Electronics N.V. Radiothérapie guidée par l'image
US10393836B2 (en) 2011-12-13 2019-08-27 Viewray Technologies, Inc. Active resistive shimming for MRI devices
US10561861B2 (en) 2012-05-02 2020-02-18 Viewray Technologies, Inc. Videographic display of real-time medical treatment
US9662512B2 (en) 2012-09-18 2017-05-30 Koninklijke Philips N.V. Magnetic resonance guided LINAC
WO2014044635A1 (fr) * 2012-09-18 2014-03-27 Koninklijke Philips N.V. Linac guidé par résonance magnétique
CN104641247A (zh) * 2012-09-18 2015-05-20 皇家飞利浦有限公司 磁共振引导的linac
RU2631910C2 (ru) * 2012-09-18 2017-09-28 Конинклейке Филипс Н.В. Линейный ускоритель, направляемый магнитным резонансом
JP2015533539A (ja) * 2012-09-18 2015-11-26 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 磁気共鳴で案内される直線加速器
US10835763B2 (en) 2012-10-26 2020-11-17 Viewray Technologies, Inc. Assessment and improvement of treatment using imaging of physiological responses to radiation therapy
US11040222B2 (en) 2012-10-26 2021-06-22 Viewray Technologies, Inc. Assessment and improvement of treatment using imaging of physiological responses to radiation therapy
US10821303B2 (en) 2012-10-26 2020-11-03 Viewray Technologies, Inc. Assessment and improvement of treatment using imaging of physiological responses to radiation therapy
US10061000B2 (en) 2012-11-06 2018-08-28 Siemens Healthcare Limited MRI magnet for radiation and particle therapy
US11612764B2 (en) 2013-03-15 2023-03-28 Viewray Technologies, Inc. Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging
US10463884B2 (en) 2013-03-15 2019-11-05 Viewray Technologies, Inc. Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging
US11083912B2 (en) 2013-03-15 2021-08-10 Viewray Technologies, Inc. Systems and methods for linear accelerator radiotherapy with magnetic resonance imaging
US10661098B2 (en) 2013-06-21 2020-05-26 Koninklijke Philips N.V. Shim system for a magnetic resonance hybrid scanner
JP2016526968A (ja) * 2013-06-21 2016-09-08 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 磁気共鳴ハイブリッドスキャナ用シムシステム
WO2014203190A1 (fr) * 2013-06-21 2014-12-24 Koninklijke Philips N.V. Système de cale destiné à un scanner hybride à résonance magnétique
US11291860B2 (en) 2013-06-21 2022-04-05 Koninklijke Philips N.V. Shim system for a magnetic resonance hybrid scanner
CN105056406B (zh) * 2015-07-31 2018-01-12 北京健联医疗科技有限公司 紧凑型磁共振引导的粒子治疗设备
CN105056406A (zh) * 2015-07-31 2015-11-18 北京健联医疗科技有限公司 紧凑型磁共振引导的粒子治疗设备
US9966160B2 (en) 2015-11-24 2018-05-08 Viewray Technologies, Inc. Radiation beam collimating systems and methods
US10413751B2 (en) 2016-03-02 2019-09-17 Viewray Technologies, Inc. Particle therapy with magnetic resonance imaging
US12017090B2 (en) 2016-03-02 2024-06-25 Viewray Systems, Inc. Particle therapy with magnetic resonance imaging
US11351398B2 (en) 2016-03-02 2022-06-07 Viewray Technologies, Inc. Particle therapy with magnetic resonance imaging
US11892523B2 (en) 2016-06-22 2024-02-06 Viewray Technologies, Inc. Magnetic resonance imaging
US11378629B2 (en) 2016-06-22 2022-07-05 Viewray Technologies, Inc. Magnetic resonance imaging
US11768257B2 (en) 2016-06-22 2023-09-26 Viewray Technologies, Inc. Magnetic resonance imaging
US11426604B2 (en) 2016-08-08 2022-08-30 Koninklijke Philips N.V. Mock-up antenna and coil system
US11931602B2 (en) 2016-12-13 2024-03-19 Viewray Technologies, Inc. Radiation therapy systems and methods
US11000706B2 (en) 2016-12-13 2021-05-11 Viewray Technologies, Inc. Radiation therapy systems and methods
US12472384B2 (en) 2016-12-13 2025-11-18 Viewray Systems, Inc. Radiation therapy systems and methods
CN106621075A (zh) * 2016-12-22 2017-05-10 上海联影医疗科技有限公司 放射治疗装置
US11033758B2 (en) 2017-12-06 2021-06-15 Viewray Technologies, Inc. Radiotherapy systems, methods and software
US11209509B2 (en) 2018-05-16 2021-12-28 Viewray Technologies, Inc. Resistive electromagnet systems and methods
US12000914B2 (en) 2018-05-16 2024-06-04 Viewray Systems, Inc. Resistive electromagnet systems and methods
CN110988523A (zh) * 2019-11-18 2020-04-10 国网河北省电力有限公司电力科学研究院 一种电力变压器绕组变形累积效应的检测方法及装置

Also Published As

Publication number Publication date
GB0221174D0 (en) 2002-10-23
AU2003274393A1 (en) 2004-04-30
GB2393373A (en) 2004-03-24

Similar Documents

Publication Publication Date Title
WO2004024235A1 (fr) Irm dans un appareil de radiotherapie guidee avec compensateurs d'heterogeneite de faisceau
GB2382512A (en) MRI in guided radiotherapy and position verification
CA2728111C (fr) Systeme de radiotherapie
US8958864B2 (en) Combined radiation therapy and magnetic resonance unit
US8487269B2 (en) Combined radiation therapy and magnetic resonance unit
CA2626538C (fr) Systeme d'irm et de radiotherapie externe integre
US11116418B2 (en) Magnetic resonance imaging and radiotherapy apparatus with at least two-transmit-and receive channels
EP2454617B1 (fr) Procédé et appareil pour blinder un accélérateur linéaire et un dispositif d'imagerie par résonance magnétique l'un de l'autre
EP2627409B1 (fr) Dispositif de déviation de faisceau dans une unité combinée de radiothérapie et de résonance magnétique
US8554302B2 (en) Apparatus having a combined magnetic resonance apparatus and radiation therapy apparatus
KR20140061271A (ko) Mri와 방사선 병용 치료 시스템
US20110196227A1 (en) Apparatus with a Combination of a Magnetic Resonance Apparatus and a Radiotherapy Apparatus
CN111228657A (zh) 一种磁共振图像引导的放射治疗系统
HK1154360B (en) Radiation therapy system

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP