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WO2004020591A3 - Methods of use for novel human polypeptides encoded by polynucleotides - Google Patents

Methods of use for novel human polypeptides encoded by polynucleotides Download PDF

Info

Publication number
WO2004020591A3
WO2004020591A3 PCT/US2003/026864 US0326864W WO2004020591A3 WO 2004020591 A3 WO2004020591 A3 WO 2004020591A3 US 0326864 W US0326864 W US 0326864W WO 2004020591 A3 WO2004020591 A3 WO 2004020591A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
polynucleotides
modulators
polypeptides encoded
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/026864
Other languages
French (fr)
Other versions
WO2004020591A2 (en
Inventor
Lewis T Williams
Keting Chu
Ernestine Lee
Kevin Hestir
Pierre Alvaro Beaurang
Dirk Behrens
Robert Forgan Halenbeck
Min Mei Huang
Srinivas Kothakota
Lin Haishan
Thomas Linnemann
Kristen Pierce
Yan Wang
Justin G P Wong
Ge Wu
Hongbing Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Five Prime Therapeutics Inc
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Priority to AU2003265787A priority Critical patent/AU2003265787A1/en
Publication of WO2004020591A2 publication Critical patent/WO2004020591A2/en
Anticipated expiration legal-status Critical
Publication of WO2004020591A3 publication Critical patent/WO2004020591A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides novel polynucleotides, related polypeptides, related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, and inflammatory, immune, bacterial, and viral disorders.
PCT/US2003/026864 2002-08-29 2003-08-28 Methods of use for novel human polypeptides encoded by polynucleotides Ceased WO2004020591A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003265787A AU2003265787A1 (en) 2002-08-29 2003-08-28 Methods of use for novel human polypeptides encoded by polynucleotides

Applications Claiming Priority (68)

Application Number Priority Date Filing Date Title
US40664602P 2002-08-29 2002-08-29
US40657902P 2002-08-29 2002-08-29
US40658502P 2002-08-29 2002-08-29
US40658802P 2002-08-29 2002-08-29
US40660802P 2002-08-29 2002-08-29
US40665302P 2002-08-29 2002-08-29
US40664202P 2002-08-29 2002-08-29
US60/406,585 2002-08-29
US60/406,653 2002-08-29
US60/406,642 2002-08-29
US60/406,608 2002-08-29
US60/406,646 2002-08-29
US60/406,588 2002-08-29
US60/406,579 2002-08-29
US41095902P 2002-09-17 2002-09-17
US41094902P 2002-09-17 2002-09-17
US41105502P 2002-09-17 2002-09-17
US41094702P 2002-09-17 2002-09-17
US41104802P 2002-09-17 2002-09-17
US41102302P 2002-09-17 2002-09-17
US41107302P 2002-09-17 2002-09-17
US41104502P 2002-09-17 2002-09-17
US41096102P 2002-09-17 2002-09-17
US41110102P 2002-09-17 2002-09-17
US41104102P 2002-09-17 2002-09-17
US41095802P 2002-09-17 2002-09-17
US41103502P 2002-09-17 2002-09-17
US41094802P 2002-09-17 2002-09-17
US60/410,958 2002-09-17
US60/410,948 2002-09-17
US60/411,023 2002-09-17
US60/411,101 2002-09-17
US60/411,035 2002-09-17
US60/411,041 2002-09-17
US60/410,947 2002-09-17
US60/411,045 2002-09-17
US60/411,073 2002-09-17
US60/410,961 2002-09-17
US60/410,949 2002-09-17
US60/410,959 2002-09-17
US60/411,048 2002-09-17
US60/411,055 2002-09-17
US46370803P 2003-04-18 2003-04-18
US46371603P 2003-04-18 2003-04-18
US60/463,708 2003-04-18
US60/463,716 2003-04-18
US46720103P 2003-05-02 2003-05-02
US46719903P 2003-05-02 2003-05-02
US60/467,199 2003-05-02
US60/467,201 2003-05-02
US47133603P 2003-05-19 2003-05-19
US60/471,336 2003-05-19
US47243003P 2003-05-22 2003-05-22
US60/472,430 2003-05-22
US47664103P 2003-06-09 2003-06-09
US60/476,641 2003-06-09
US48522403P 2003-07-08 2003-07-08
US48521803P 2003-07-08 2003-07-08
US60/485,218 2003-07-08
US60/485,224 2003-07-08
US48644603P 2003-07-14 2003-07-14
US60/486,446 2003-07-14
US48689103P 2003-07-15 2003-07-15
US60/486,891 2003-07-15
US49334103P 2003-08-08 2003-08-08
US49357703P 2003-08-08 2003-08-08
US60/493,577 2003-08-08
US60/493,341 2003-08-08

Publications (2)

Publication Number Publication Date
WO2004020591A2 WO2004020591A2 (en) 2004-03-11
WO2004020591A3 true WO2004020591A3 (en) 2005-03-24

Family

ID=34317894

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/026864 Ceased WO2004020591A2 (en) 2002-08-29 2003-08-28 Methods of use for novel human polypeptides encoded by polynucleotides

Country Status (2)

Country Link
AU (1) AU2003265787A1 (en)
WO (1) WO2004020591A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8981061B2 (en) 2001-03-20 2015-03-17 Novo Nordisk A/S Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
WO2013120554A1 (en) 2012-02-15 2013-08-22 Novo Nordisk A/S Antibodies that bind peptidoglycan recognition protein 1
US9550830B2 (en) 2012-02-15 2017-01-24 Novo Nordisk A/S Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
LT2814844T (en) 2012-02-15 2017-10-25 Novo Nordisk A/S Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (trem-1)
CN113214397A (en) 2014-07-17 2021-08-06 诺和诺德股份有限公司 Site-directed mutagenesis of TREM-1 antibodies to reduce viscosity
MY206833A (en) 2018-04-02 2025-01-09 Bristol Myers Squibb Co Anti-trem-1 antibodies and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010025098A1 (en) * 1998-03-13 2001-09-27 Incyte Pharmaceuticals, Inc. Human membrane-spanning proteins
US6555654B1 (en) * 1997-04-15 2003-04-29 The Wellcome Trust Limited As Trustee For The Wellcome Trust LDL-receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555654B1 (en) * 1997-04-15 2003-04-29 The Wellcome Trust Limited As Trustee For The Wellcome Trust LDL-receptor
US20010025098A1 (en) * 1998-03-13 2001-09-27 Incyte Pharmaceuticals, Inc. Human membrane-spanning proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BROWN ET AL.: "Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family", BIOCHEMICAL AND BIPHYSICAL RESEARCH COMMUNICATIONS, vol. 248, no. 3, July 1998 (1998-07-01), pages 879 - 888, XP002249367 *

Also Published As

Publication number Publication date
WO2004020591A2 (en) 2004-03-11
AU2003265787A8 (en) 2004-03-19
AU2003265787A1 (en) 2004-03-19

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