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WO2004017070A3 - Surface de capteur possedant un rapport signal/bruit ameliore - Google Patents

Surface de capteur possedant un rapport signal/bruit ameliore Download PDF

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Publication number
WO2004017070A3
WO2004017070A3 PCT/DE2003/002452 DE0302452W WO2004017070A3 WO 2004017070 A3 WO2004017070 A3 WO 2004017070A3 DE 0302452 W DE0302452 W DE 0302452W WO 2004017070 A3 WO2004017070 A3 WO 2004017070A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensor surface
noise ratio
improved signal
relates
calf serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE2003/002452
Other languages
German (de)
English (en)
Other versions
WO2004017070A2 (fr
Inventor
Holger Klapproth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TDK Micronas GmbH
Original Assignee
TDK Micronas GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TDK Micronas GmbH filed Critical TDK Micronas GmbH
Priority to EP03787705A priority Critical patent/EP1525475B1/fr
Priority to DE10393508T priority patent/DE10393508D2/de
Priority to DE50305770T priority patent/DE50305770D1/de
Priority to AU2003250797A priority patent/AU2003250797A1/en
Priority to US10/521,817 priority patent/US20060115906A1/en
Publication of WO2004017070A2 publication Critical patent/WO2004017070A2/fr
Publication of WO2004017070A3 publication Critical patent/WO2004017070A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

L'invention concerne une surface de capteur possédant un rapport signal/bruit amélioré grâce à un réactif de blocage immobilisé de façon covalente sur ladite surface. L'invention concerne également des systèmes comprenant de telles surfaces, ainsi que des procédés faisant appel à ces surfaces et à ces systèmes.
PCT/DE2003/002452 2002-07-22 2003-07-21 Surface de capteur possedant un rapport signal/bruit ameliore Ceased WO2004017070A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP03787705A EP1525475B1 (fr) 2002-07-22 2003-07-21 Surface de capteur possedant un rapport signal/bruit ameliore
DE10393508T DE10393508D2 (de) 2002-07-22 2003-07-21 Sensroberfläche mit Verbessertem Signal/Rausch-Verhältnis
DE50305770T DE50305770D1 (de) 2002-07-22 2003-07-21 Sensoroberfläche mit verbessertem signal/rausch-verhältnis
AU2003250797A AU2003250797A1 (en) 2002-07-22 2003-07-21 Sensor surface comprising an improved signal-noise ratio
US10/521,817 US20060115906A1 (en) 2002-07-22 2003-07-21 Sensor surface comprising an improved signal-noise ratio

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10233303A DE10233303A1 (de) 2002-07-22 2002-07-22 Sensoroberfläche mit verbessertem Signal/Rausch-Verhältnis
DE10233303.3 2002-07-22

Publications (2)

Publication Number Publication Date
WO2004017070A2 WO2004017070A2 (fr) 2004-02-26
WO2004017070A3 true WO2004017070A3 (fr) 2004-05-27

Family

ID=30128243

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2003/002452 Ceased WO2004017070A2 (fr) 2002-07-22 2003-07-21 Surface de capteur possedant un rapport signal/bruit ameliore

Country Status (5)

Country Link
US (1) US20060115906A1 (fr)
EP (1) EP1525475B1 (fr)
AU (1) AU2003250797A1 (fr)
DE (3) DE10233303A1 (fr)
WO (1) WO2004017070A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0711236D0 (en) * 2007-06-11 2007-07-18 Oxford Biosensors Ltd Lipoprotein surfactant
GB0822725D0 (en) * 2008-12-12 2009-01-21 Oxford Biosensors Ltd Channel
EP2230515B1 (fr) * 2009-03-16 2014-12-17 Agilent Technologies, Inc. Passivation de surfaces après couplage de ligands
JP7209498B2 (ja) * 2017-09-15 2023-01-20 富士レビオ株式会社 Ｂ型肝炎ウイルスコア抗体の免疫測定方法
CN112946253B (zh) * 2019-12-11 2022-11-08 广东菲鹏生物有限公司 用于免疫诊断试剂中固相载体的封闭阶段处理剂及应用和产品
KR102291723B1 (ko) * 2020-01-15 2021-08-20 재단법인대구경북과학기술원 면역 블롯팅용 블로킹 조성물 및 이의 용도
CN116930513B (zh) * 2023-09-19 2023-11-17 北京索莱宝科技有限公司 一种用于蛋白检测的无蛋白快速封闭液及其应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012539A1 (fr) * 1996-09-17 1998-03-26 Meso Scale Technologies, Llc Mesure d'electrochimioluminescence multi-groupement et multi-spe cifique
EP0874242A1 (fr) * 1997-04-21 1998-10-28 Randox Laboratories Ltd. Dispositif et appareil pour la détection simultanée de plusieurs analytes
WO1999043688A1 (fr) * 1998-02-24 1999-09-02 Surmodics, Inc. Derives d'acides nucleiques photo-activables
WO2001094946A2 (fr) * 2000-06-05 2001-12-13 Chiron Corporation Microreseaux permettant de realiser des analyses proteomiques
US20020055093A1 (en) * 2000-02-16 2002-05-09 Abbott Nicholas L. Biochemical blocking layer for liquid crystal assay
EP1215287A2 (fr) * 2000-12-13 2002-06-19 Fuji Photo Film Co., Ltd. Procédé de blocage d'un appareil, qui est utilisé pour détecter des molécules biochimiquement actives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965106A (en) * 1992-03-04 1999-10-12 Perimmune Holdings, Inc. In vivo binding pair pretargeting
US5516703A (en) * 1993-08-20 1996-05-14 The University Of Utah Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
AU720963B2 (en) * 1995-05-26 2000-06-15 Surmodics, Inc. Method and implantable article for promoting endothelialization
DE19703718A1 (de) * 1996-01-23 1997-07-24 Inst Chemo Biosensorik Affinitätssensoren und -assays
WO1998028623A1 (fr) * 1996-12-20 1998-07-02 Gamera Bioscience Corporation Systeme a base de liaisons par affinite permettant de detecter des particules dans un fluide
US20030027214A1 (en) * 1999-02-17 2003-02-06 Kamb Carl Alexander Methods for substrate-ligand interaction screening
US7771922B2 (en) * 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012539A1 (fr) * 1996-09-17 1998-03-26 Meso Scale Technologies, Llc Mesure d'electrochimioluminescence multi-groupement et multi-spe cifique
EP0874242A1 (fr) * 1997-04-21 1998-10-28 Randox Laboratories Ltd. Dispositif et appareil pour la détection simultanée de plusieurs analytes
WO1999043688A1 (fr) * 1998-02-24 1999-09-02 Surmodics, Inc. Derives d'acides nucleiques photo-activables
US20020055093A1 (en) * 2000-02-16 2002-05-09 Abbott Nicholas L. Biochemical blocking layer for liquid crystal assay
WO2001094946A2 (fr) * 2000-06-05 2001-12-13 Chiron Corporation Microreseaux permettant de realiser des analyses proteomiques
EP1215287A2 (fr) * 2000-12-13 2002-06-19 Fuji Photo Film Co., Ltd. Procédé de blocage d'un appareil, qui est utilisé pour détecter des molécules biochimiquement actives

Also Published As

Publication number Publication date
AU2003250797A1 (en) 2004-03-03
EP1525475B1 (fr) 2006-11-22
WO2004017070A2 (fr) 2004-02-26
DE10393508D2 (de) 2005-06-23
DE50305770D1 (de) 2007-01-04
US20060115906A1 (en) 2006-06-01
DE10233303A1 (de) 2004-02-12
EP1525475A2 (fr) 2005-04-27

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