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WO2004009842A3 - Methods for identifying genes related to malfunctions of the central nervous system - Google Patents

Methods for identifying genes related to malfunctions of the central nervous system Download PDF

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Publication number
WO2004009842A3
WO2004009842A3 PCT/DK2003/000509 DK0300509W WO2004009842A3 WO 2004009842 A3 WO2004009842 A3 WO 2004009842A3 DK 0300509 W DK0300509 W DK 0300509W WO 2004009842 A3 WO2004009842 A3 WO 2004009842A3
Authority
WO
WIPO (PCT)
Prior art keywords
malfunctions
methods
nervous system
central nervous
genes related
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2003/000509
Other languages
French (fr)
Other versions
WO2004009842A2 (en
Inventor
Leif Kongskov Larsen
Niels Vrang
Philip Just Larsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rheoscience AS
Original Assignee
Rheoscience AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheoscience AS filed Critical Rheoscience AS
Priority to EP03740117A priority Critical patent/EP1523576A2/en
Priority to AU2003281540A priority patent/AU2003281540A1/en
Publication of WO2004009842A2 publication Critical patent/WO2004009842A2/en
Publication of WO2004009842A3 publication Critical patent/WO2004009842A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to methods for identification of genes related to malfunctions of the central nervous system. In particular the present invention relates to identification of genes that are differentially expressed in hypothalamic subregions. Further aspects of the present invention relates to DNA sequences as well as recombinant polypeptides and uses thereof in prophylaxis, diagnosis and treatment of hypothalamic disorders.
PCT/DK2003/000509 2002-07-24 2003-07-23 Methods for identifying genes related to malfunctions of the central nervous system Ceased WO2004009842A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP03740117A EP1523576A2 (en) 2002-07-24 2003-07-23 Methods for identifying genes related to malfunctions of the central nervous system
AU2003281540A AU2003281540A1 (en) 2002-07-24 2003-07-23 Methods for identifying genes related to malfunctions of the central nervous system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200201131 2002-07-24
DKPA200201131 2002-07-24
US39894202P 2002-07-25 2002-07-25
US60/398,942 2002-07-25

Publications (2)

Publication Number Publication Date
WO2004009842A2 WO2004009842A2 (en) 2004-01-29
WO2004009842A3 true WO2004009842A3 (en) 2004-03-18

Family

ID=30771914

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2003/000509 Ceased WO2004009842A2 (en) 2002-07-24 2003-07-23 Methods for identifying genes related to malfunctions of the central nervous system

Country Status (3)

Country Link
EP (1) EP1523576A2 (en)
AU (1) AU2003281540A1 (en)
WO (1) WO2004009842A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2587979A1 (en) * 2004-11-19 2006-05-26 Oy Jurilab Ltd Method and kit for detecting a risk of essential arterial hypertension
CN105504873B (en) * 2015-11-26 2017-10-10 龚林 Dye composite, dye liquor and the colouring method dyed for nerve fiber tigroid body

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI [online] 1 October 2000 (2000-10-01), BONALDO ET AL.: "Mus musculus cDNA clone", XP002241112, Database accession no. BE863083 *
GAUTVIK ET AL.: "Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction", PROC. NATL. ACAD. SCI. USA, vol. 93, August 1996 (1996-08-01), pages 8733 - 8738, XP002241111 *
LEVIN ET AL.: "Differential stress responsivity in diet-induced obese and resistant rats", AM J PHYSIOL REGULATORY INTEGRATIVE COMP PHYSIOL, vol. 279, 2000, pages R1357 - R1364, XP002241114 *
MARATOS-FLIER E ET AL: "ANALYSIS OF GENE EXPRESSION IN HYPOTHALAMUS IN OBESE AND NORMAL MICE USING DIFFERENTIAL DISPLAY", METHODS IN MOLECULAR BIOLOGY, HUMANA PRESS INC., CLIFTON, NJ, US, vol. 85, 1997, pages 297 - 304, XP008004618 *
ZIOTOPOULOU ET AL.: "Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice", AM J PHYSIOL ENDOCRINOL METAB, vol. 279, 2000, pages E838 - E845, XP002241110 *

Also Published As

Publication number Publication date
AU2003281540A1 (en) 2004-02-09
EP1523576A2 (en) 2005-04-20
WO2004009842A2 (en) 2004-01-29

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