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WO2004096988A3 - Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance - Google Patents

Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance Download PDF

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Publication number
WO2004096988A3
WO2004096988A3 PCT/US2004/012450 US2004012450W WO2004096988A3 WO 2004096988 A3 WO2004096988 A3 WO 2004096988A3 US 2004012450 W US2004012450 W US 2004012450W WO 2004096988 A3 WO2004096988 A3 WO 2004096988A3
Authority
WO
WIPO (PCT)
Prior art keywords
biocatalysts
magnetic resonance
nuclear magnetic
discovery
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/012450
Other languages
French (fr)
Other versions
WO2004096988A2 (en
WO2004096988A8 (en
Inventor
Venkiteswaran Subramanian
Christopher P Christenson
Claire B Conboy
Kai Li
Oscar David Redwine
Lamy Jean Chopin Iii
Barbara A Miller
Paul L Morabito
Richard C Winterton
Bettina M Rosner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Publication of WO2004096988A2 publication Critical patent/WO2004096988A2/en
Publication of WO2004096988A3 publication Critical patent/WO2004096988A3/en
Publication of WO2004096988A8 publication Critical patent/WO2004096988A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to methods and apparatus for the screening of biocatalysts. In particular, the present invention relates to high throughput nuclear magnetic resonance methods for the screening of biocatalysts to identify biocatalytic activities and to discover biocatalysts. The present invention further provides improved high-throughput nuclear magnetic resonance analysis systems.
PCT/US2004/012450 2003-04-25 2004-04-22 Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance Ceased WO2004096988A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46570003P 2003-04-25 2003-04-25
US60/465,700 2003-04-25

Publications (3)

Publication Number Publication Date
WO2004096988A2 WO2004096988A2 (en) 2004-11-11
WO2004096988A3 true WO2004096988A3 (en) 2005-04-07
WO2004096988A8 WO2004096988A8 (en) 2005-07-21

Family

ID=33418274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012450 Ceased WO2004096988A2 (en) 2003-04-25 2004-04-22 Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance

Country Status (1)

Country Link
WO (1) WO2004096988A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088613B2 (en) 1999-12-29 2012-01-03 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521216B2 (en) 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
WO2003106415A2 (en) 2002-06-13 2003-12-24 Diversa Corporation Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
DK2115153T3 (en) * 2007-03-01 2013-09-08 Bp Corp North America Inc Nitrilases, nucleic acids encoding them, and methods of preparing and using them

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770438A (en) * 1994-11-01 1998-06-23 Takeda Chemical Industries, Ltd. Process for enantioselective hydrolysis of α-(2-amino)-phenyl-benzenemethanol ester type compounds using bacillus, pseudomonas or streptomyces
US6187578B1 (en) * 1996-05-20 2001-02-13 Novo Nordisk Biotech, Inc. Carboxypeptidases and nucleic acids encoding the same
US20020168711A1 (en) * 2000-01-31 2002-11-14 Rosen Craig A. Nucleic acids, proteins, and antibodies
US20030044800A1 (en) * 2000-09-05 2003-03-06 Connelly Patrick R. Drug discovery employing calorimetric target triage

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770438A (en) * 1994-11-01 1998-06-23 Takeda Chemical Industries, Ltd. Process for enantioselective hydrolysis of α-(2-amino)-phenyl-benzenemethanol ester type compounds using bacillus, pseudomonas or streptomyces
US6187578B1 (en) * 1996-05-20 2001-02-13 Novo Nordisk Biotech, Inc. Carboxypeptidases and nucleic acids encoding the same
US20020168711A1 (en) * 2000-01-31 2002-11-14 Rosen Craig A. Nucleic acids, proteins, and antibodies
US20030044800A1 (en) * 2000-09-05 2003-03-06 Connelly Patrick R. Drug discovery employing calorimetric target triage

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088613B2 (en) 1999-12-29 2012-01-03 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them

Also Published As

Publication number Publication date
WO2004096988A2 (en) 2004-11-11
WO2004096988A8 (en) 2005-07-21

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