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WO2004087105A8 - Formulations associant du platine et des fluoropyrimidines - Google Patents

Formulations associant du platine et des fluoropyrimidines

Info

Publication number
WO2004087105A8
WO2004087105A8 PCT/CA2004/000508 CA2004000508W WO2004087105A8 WO 2004087105 A8 WO2004087105 A8 WO 2004087105A8 CA 2004000508 W CA2004000508 W CA 2004000508W WO 2004087105 A8 WO2004087105 A8 WO 2004087105A8
Authority
WO
WIPO (PCT)
Prior art keywords
fluoropyrimidines
combination formulations
platinum agents
platinum
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA2004/000508
Other languages
English (en)
Other versions
WO2004087105A1 (fr
Inventor
Lawrence Mayer
Marcel Bally
Murray Webb
Paul Tardi
Clifford Shew
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CELATOR TECHNOLOGIES Inc
Original Assignee
CELATOR TECHNOLOGIES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CELATOR TECHNOLOGIES Inc filed Critical CELATOR TECHNOLOGIES Inc
Publication of WO2004087105A1 publication Critical patent/WO2004087105A1/fr
Publication of WO2004087105A8 publication Critical patent/WO2004087105A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des compositions qui comprennent des liposomes auxquels sont associés, de manière stable, du platine et un antimétabolite. Ces compositions permettent d'obtenir des effets thérapeutiques améliorés lorsque les combinaisons de ces médicaments sont administrées.
PCT/CA2004/000508 2003-04-02 2004-04-02 Formulations associant du platine et des fluoropyrimidines Ceased WO2004087105A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46025103P 2003-04-02 2003-04-02
US60/460,251 2003-04-02

Publications (2)

Publication Number Publication Date
WO2004087105A1 WO2004087105A1 (fr) 2004-10-14
WO2004087105A8 true WO2004087105A8 (fr) 2005-03-10

Family

ID=33131918

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2004/000508 Ceased WO2004087105A1 (fr) 2003-04-02 2004-04-02 Formulations associant du platine et des fluoropyrimidines

Country Status (1)

Country Link
WO (1) WO2004087105A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2574767C (fr) 2004-07-19 2015-02-17 Celator Pharmaceuticals, Inc. Produits de synthese particulaires destines a la liberation d'agents actifs
WO2006032136A1 (fr) * 2004-09-20 2006-03-30 British Columbia Cancer Agency Branch Gemcitabine libre ou encapsulee dans des liposomes seule ou en association avec de l'idarubicine libre ou encapsulee dans des liposomes
US20080107722A1 (en) * 2004-11-18 2008-05-08 Paul Tardi Method For Loading Multiple Agents Into Delivery Vehicles
FR2891843A1 (fr) * 2005-10-06 2007-04-13 Erytech Pharma Soc Par Actions Erythrocytes contenant du 5-fluorouracile
EP1959940A4 (fr) * 2005-11-30 2013-04-03 Celator Pharmaceuticals Inc Administration localisee de combinaisons de medicaments
WO2009097011A1 (fr) 2007-08-17 2009-08-06 Celator Pharmaceuticals, Inc. Préparations améliorées de médicaments au platine
EP2123258A1 (fr) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes pour l'administration de médicaments
CA3157379A1 (fr) * 2019-10-10 2021-04-15 The University Of North Carolina At Chapel Hill Complexes de systeme d'administration comprenant un precipite d'un agent actif et procedes d'utilisation
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2206478T3 (es) * 1994-11-11 2004-05-16 Debiopharm S.A. Composiciones carcinostaticas que contienen cis-oxaliplatino y otra u otras sustancias carcinostaticas compatibles.
DE19724796A1 (de) * 1997-06-06 1998-12-10 Max Delbrueck Centrum Mittel zur Antitumortherapie
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
EP1427393A2 (fr) * 2000-05-02 2004-06-16 Pharmacept GmbH Liposomes a base de principes actifs
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
CZ20032266A3 (cs) * 2001-03-06 2004-02-18 Bristol-Myers Squibb Company Dávkovací formy pro ošetřování nádorů
DE60216305T2 (de) * 2001-10-03 2007-07-05 Celator Pharmaceuticals, Inc. Zusammensetzungen und Verfahren zur Abgabe von Arzneimittelkombinationen

Also Published As

Publication number Publication date
WO2004087105A1 (fr) 2004-10-14

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WO2004087105A8 (fr) Formulations associant du platine et des fluoropyrimidines

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