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WO2004083369A3 - Composition de fixation tissulaire - Google Patents

Composition de fixation tissulaire Download PDF

Info

Publication number
WO2004083369A3
WO2004083369A3 PCT/FR2004/000608 FR2004000608W WO2004083369A3 WO 2004083369 A3 WO2004083369 A3 WO 2004083369A3 FR 2004000608 W FR2004000608 W FR 2004000608W WO 2004083369 A3 WO2004083369 A3 WO 2004083369A3
Authority
WO
WIPO (PCT)
Prior art keywords
binding composition
tissue binding
preferably approximately
composition
tissue
Prior art date
Application number
PCT/FR2004/000608
Other languages
English (en)
Other versions
WO2004083369A2 (fr
Inventor
Philippe Rochaix
Original Assignee
Inst Claudius Regaud
Philippe Rochaix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Claudius Regaud, Philippe Rochaix filed Critical Inst Claudius Regaud
Priority to AU2004221625A priority Critical patent/AU2004221625B2/en
Priority to CA002518981A priority patent/CA2518981A1/fr
Priority to EP04720046A priority patent/EP1601950A2/fr
Priority to US10/548,567 priority patent/US20070072167A1/en
Priority to NZ542908A priority patent/NZ542908A/en
Publication of WO2004083369A2 publication Critical patent/WO2004083369A2/fr
Publication of WO2004083369A3 publication Critical patent/WO2004083369A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Composition de fixation tissulaire caractérisée en ce qu'elle comprend : - du tréhalose à une concentration comprise entre 40 g/l et 80 g/l, de préférence d'environ 60 g/l, - de l'éthanol en une quantité comprise entre 40 % et 80 % (v/v), de préférence environ 70 % (v/v), - de l'acide acétique en une quantité comprise entre 0 % et 5 % (v/v), de préférence environ 1 % (v/v), et - de l'eau en une quantité comprise entre 20 % et 60 % (v/v), de préférence environ 29 % (v/v).
PCT/FR2004/000608 2003-03-12 2004-03-12 Composition de fixation tissulaire WO2004083369A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2004221625A AU2004221625B2 (en) 2003-03-12 2004-03-12 Tissue binding composition
CA002518981A CA2518981A1 (fr) 2003-03-12 2004-03-12 Composition de fixation tissulaire
EP04720046A EP1601950A2 (fr) 2003-03-12 2004-03-12 Composition de fixation tissulaire
US10/548,567 US20070072167A1 (en) 2003-03-12 2004-03-12 Tissue binding composition
NZ542908A NZ542908A (en) 2003-03-12 2004-03-12 Tissue fixing composition based on non-toxic chemical compounds that preserve cell and tissue structures, and provides easy handling as it allows tissue samples to be conserved in a paraffin block or in dehydrated form

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0303043A FR2852392B1 (fr) 2003-03-12 2003-03-12 Composition de fixation tissulaire
FR03/03043 2003-03-12

Publications (2)

Publication Number Publication Date
WO2004083369A2 WO2004083369A2 (fr) 2004-09-30
WO2004083369A3 true WO2004083369A3 (fr) 2005-01-20

Family

ID=32893233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/000608 WO2004083369A2 (fr) 2003-03-12 2004-03-12 Composition de fixation tissulaire

Country Status (7)

Country Link
US (1) US20070072167A1 (fr)
EP (1) EP1601950A2 (fr)
AU (1) AU2004221625B2 (fr)
CA (1) CA2518981A1 (fr)
FR (1) FR2852392B1 (fr)
NZ (1) NZ542908A (fr)
WO (1) WO2004083369A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006040315B4 (de) * 2006-08-29 2008-06-05 Biosepar -Gesellschaft für Medizin- und Labortechnik mbH Fixativum zum Fixieren von biologischen Materialien
WO2010012002A1 (fr) * 2008-07-25 2010-01-28 Saryna Medical Corporation Procédés et systèmes pour l'analyse génétique des érythrocytes nucléés fœtaux
EP2202320A1 (fr) 2008-12-24 2010-06-30 Agendia B.V. Procédés et moyens pour le typage d'un échantillon comprenant des cellules colorectales cancéreuses
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
JP2013531987A (ja) 2010-06-14 2013-08-15 キアゲン ゲーエムベーハー 固定生物学的試料から生体分子を抽出するためのターゲット細胞または組織を決定するための方法
AU2011308134B2 (en) 2010-09-28 2015-09-03 Agendia N.V. Methods and means for typing a sample comprising cancer cells based on oncogenic signal transduction pathways
WO2012087144A2 (fr) 2010-12-23 2012-06-28 Agendia N.V. Procédés et moyens de classification moléculaire des cancers colorectaux
US9175351B2 (en) 2011-07-13 2015-11-03 Agendia N.V. Means and methods for molecular classification of breast cancer
WO2013192606A1 (fr) 2012-06-22 2013-12-27 Leica Biosystems Nussloch Gmbh Dispositif de transport d'échantillon de tissu de biopsie et son procédé d'utilisation
EP2864754B1 (fr) 2012-06-22 2020-08-26 Leica Biosystems Nussloch GmbH Récipient pour échantillon de tissu
EP2906712A1 (fr) 2012-10-10 2015-08-19 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Procédés et moyens de prédiction de résistance à un traitement anti-cancer
EP2922972B1 (fr) 2012-11-26 2017-04-26 Ecole Polytechnique Fédérale de Lausanne (EPFL) Classification de cancer colorectal à l'aide de pronostic différentiel et de réponses thérapeutiques personnalisées
US9097629B2 (en) 2013-03-15 2015-08-04 Leica Biosystems Nussloch Gmbh Tissue cassette with retractable member
CA2845832C (fr) 2013-03-15 2020-09-22 Leica Biosystems Nussloch Gmbh Cassette de tissu a element de sollicitation
US9052256B2 (en) 2013-03-15 2015-06-09 Leica Biosystems Nussloch Gmbh Method for processing and embedding tissue
EP3074532A1 (fr) 2013-11-28 2016-10-05 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Méthodes pour la classification moléculaire du cancer du sein et/ou de l'ovaire de type brca
US20180051346A1 (en) 2015-03-17 2018-02-22 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Methods and means for subtyping invasive lobular breast cancer
WO2016153344A1 (fr) 2015-03-20 2016-09-29 Iq Products B.V. Nouveau marqueur du diabète gestationnel
WO2016153355A2 (fr) 2015-03-26 2016-09-29 Microbiome Limited Nouvelle régulation de processus d'isolation et d'amplification
WO2017017283A1 (fr) 2015-07-30 2017-02-02 Qiagen Gmbh Procédé de préparation d'un échantillon biologique congelé
US11313772B2 (en) * 2015-11-13 2022-04-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Fixatives and methods of use
WO2018128544A1 (fr) 2017-01-06 2018-07-12 Agendia N.V. Biomarqueurs pour la sélection de groupes de patients, et leurs utilisations
US20190360051A1 (en) 2017-02-17 2019-11-28 Stichting Vumc Swarm intelligence-enhanced diagnosis and therapy selection for cancer using tumor- educated platelets
WO2020022891A2 (fr) 2018-07-26 2020-01-30 Stichting Vumc Biomarqueurs pour fibrillation auriculaire
CN109115585A (zh) * 2018-08-23 2019-01-01 钱金林 一种可提高染色质量的全自动组织切片染色机及其方法
EP4143344A1 (fr) 2020-04-27 2023-03-08 Agendia N.V. Traitement du cancer du sein her2 négatif, mammaprint high risk 2
EP4145105A1 (fr) 2021-09-06 2023-03-08 Anacyte Laboratories GmbH Solution pour le prélèvement de cellules

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311035A2 (fr) * 1987-10-09 1989-04-12 Dr. Barry A. Siegfried Fixateur histologique
US4839194A (en) * 1985-07-05 1989-06-13 Bone Diagnostic Center Methods of preparing tissue samples
US5648222A (en) * 1994-07-27 1997-07-15 The Trustees Of Columbia University In The City Of New York Method for preserving cells, and uses of said method
US5849517A (en) * 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US20020094577A1 (en) * 1998-06-30 2002-07-18 Guirguis Raouf A. Cytological and histological fixative composition and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020076445A1 (en) * 2000-02-10 2002-06-20 Crowe John H. Eukaryotic cells and method for preserving cells

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839194A (en) * 1985-07-05 1989-06-13 Bone Diagnostic Center Methods of preparing tissue samples
EP0311035A2 (fr) * 1987-10-09 1989-04-12 Dr. Barry A. Siegfried Fixateur histologique
US5849517A (en) * 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5648222A (en) * 1994-07-27 1997-07-15 The Trustees Of Columbia University In The City Of New York Method for preserving cells, and uses of said method
US20020094577A1 (en) * 1998-06-30 2002-07-18 Guirguis Raouf A. Cytological and histological fixative composition and methods of use

Also Published As

Publication number Publication date
CA2518981A1 (fr) 2004-09-30
EP1601950A2 (fr) 2005-12-07
WO2004083369A2 (fr) 2004-09-30
FR2852392B1 (fr) 2005-07-08
AU2004221625A1 (en) 2004-09-30
NZ542908A (en) 2008-02-29
US20070072167A1 (en) 2007-03-29
FR2852392A1 (fr) 2004-09-17
AU2004221625B2 (en) 2009-07-09

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