[go: up one dir, main page]

WO2004083185A3 - Composes imidazole - Google Patents

Composes imidazole Download PDF

Info

Publication number
WO2004083185A3
WO2004083185A3 PCT/EP2004/002831 EP2004002831W WO2004083185A3 WO 2004083185 A3 WO2004083185 A3 WO 2004083185A3 EP 2004002831 W EP2004002831 W EP 2004002831W WO 2004083185 A3 WO2004083185 A3 WO 2004083185A3
Authority
WO
WIPO (PCT)
Prior art keywords
phenyl substituted
imidazole derivatives
substituted imidazole
compounds
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/002831
Other languages
English (en)
Other versions
WO2004083185A2 (fr
Inventor
Gerard Martin Paul Giblin
Adrian Hall
Xiao Qing Lewell
Neil Derek Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of WO2004083185A2 publication Critical patent/WO2004083185A2/fr
Publication of WO2004083185A3 publication Critical patent/WO2004083185A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés de formule (I) ou un dérivé pharmaceutiquement acceptable de ceux-ci. Dans cette formule, A, B, Z, R1, R2a, R2b, Rx, R8, R9, Q et T sont définis dans la description. L'invention concerne un procédé de préparation de tels composés, des compositions pharmaceutiques comprenant de tels composés et l'utilisation de tels composés en médecine.
PCT/EP2004/002831 2003-03-19 2004-03-17 Composes imidazole Ceased WO2004083185A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0306329.4A GB0306329D0 (en) 2003-03-19 2003-03-19 Compounds
GB0306329.4 2003-03-19

Publications (2)

Publication Number Publication Date
WO2004083185A2 WO2004083185A2 (fr) 2004-09-30
WO2004083185A3 true WO2004083185A3 (fr) 2004-11-04

Family

ID=9955103

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/002831 Ceased WO2004083185A2 (fr) 2003-03-19 2004-03-17 Composes imidazole

Country Status (2)

Country Link
GB (1) GB0306329D0 (fr)
WO (1) WO2004083185A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7446222B2 (en) 2002-11-01 2008-11-04 Glaxo Group Limited Phenyl compounds
US7759369B2 (en) 2004-12-23 2010-07-20 Glaxo Group Limited Pyridine compounds for the treatment of prostaglandin mediated diseases

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0323585D0 (en) * 2003-10-08 2003-11-12 Glaxo Group Ltd Compounds
JP2007509104A (ja) * 2003-10-24 2007-04-12 グラクソ　グループ　リミテッド 複素環式化合物
GB0606876D0 (en) * 2006-04-05 2006-05-17 Glaxo Group Ltd Compounds
WO2010007943A1 (fr) 2008-07-17 2010-01-21 旭化成ファーマ株式会社 Composé hétérocyclique azoté
CN102089302A (zh) 2008-07-17 2011-06-08 旭化成制药株式会社 含氮二环性杂环化合物
EP2570125A1 (fr) * 2011-09-16 2013-03-20 Almirall, S.A. Ligands du récepteur Ep1
MX381819B (es) 2014-08-04 2025-03-13 Nuevolution As Derivados de heterociclico opcionalmente condensados de pirimidina útiles para el tratamiento de enfermedades inflamatorias, metabólicas oncológicas y autoinmunitarias.
MX2022007265A (es) 2019-12-20 2022-09-09 Nuevolution As Compuestos activos frente a receptores nucleares.
JP7746259B2 (ja) 2019-12-20 2025-09-30 ヌエヴォリューション・アクティーゼルスカブ 核内受容体に対して活性の化合物
EP4126875A1 (fr) 2020-03-31 2023-02-08 Nuevolution A/S Composés actifs vis-à-vis des récepteurs nucléaires
WO2021198955A1 (fr) 2020-03-31 2021-10-07 Nuevolution A/S Composés actifs vis-à-vis des récepteurs nucléaires

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019814A2 (fr) * 1999-09-14 2001-03-22 Merck Frosst Canada & Co. Acides carboxyliques et acylsulfonamides, compositions contenant de tels composes et methodes de traitement
WO2002015902A1 (fr) * 2000-08-23 2002-02-28 Merck & Co., Inc. Procede pour traiter et prevenir l'incontinence urinaire par utilisation d'antagonistes de recepteur ep1 de prostanoide
EP1270559A1 (fr) * 2000-03-23 2003-01-02 J. URIACH & CIA. S.A. Nouveaux derives d'imidazole avec activite anti-inflammatoire
WO2003101959A1 (fr) * 2002-05-31 2003-12-11 Glaxo Group Limited Composes pyrroliques destines au traitement de maladies induites par prostaglandine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019814A2 (fr) * 1999-09-14 2001-03-22 Merck Frosst Canada & Co. Acides carboxyliques et acylsulfonamides, compositions contenant de tels composes et methodes de traitement
EP1270559A1 (fr) * 2000-03-23 2003-01-02 J. URIACH & CIA. S.A. Nouveaux derives d'imidazole avec activite anti-inflammatoire
WO2002015902A1 (fr) * 2000-08-23 2002-02-28 Merck & Co., Inc. Procede pour traiter et prevenir l'incontinence urinaire par utilisation d'antagonistes de recepteur ep1 de prostanoide
WO2003101959A1 (fr) * 2002-05-31 2003-12-11 Glaxo Group Limited Composes pyrroliques destines au traitement de maladies induites par prostaglandine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7446222B2 (en) 2002-11-01 2008-11-04 Glaxo Group Limited Phenyl compounds
US7759369B2 (en) 2004-12-23 2010-07-20 Glaxo Group Limited Pyridine compounds for the treatment of prostaglandin mediated diseases

Also Published As

Publication number Publication date
GB0306329D0 (en) 2003-04-23
WO2004083185A2 (fr) 2004-09-30

Similar Documents

Publication Publication Date Title
WO2004039753A3 (fr) Composes a base de phenyle
WO2006087543A8 (fr) Composés antibactériens dérivés de pipéridine
WO2007107470A3 (fr) Pyrazoles utiles comme inhibiteurs de 11-beta-hsd-1
MXPA03010877A (es) Derivados de 2-anilin-pirimida como inhibidores de cinasa dependientes de ciclina.
NO20085078L (no) Nye forbindelser
WO2007082808A3 (fr) Thiazoles en tant qu'inhibiteurs de 11 beta-hsd1
WO2008006795A3 (fr) Composés d'indole
MX2009006334A (es) Derivados de heteroaril-pirrolidinil- y -piperidinil-cetona.
NO20072515L (no) 2-amido-4-fenyltnazolderivater, fremstilling og terapeutsik anvendelse derav
DE602004011966D1 (en) Heterocyclylverbindungen
TW200640865A (en) Compounds
TW200643013A (en) Pyrazoles
GB0109122D0 (en) Novel compounds
UA86776C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
WO2004014388A8 (fr) Derives d'heteroaryles fusionnes en 6,6 utilises comme inhibiteurs de metalloproteases matricielles
WO2004096823A3 (fr) Nouveaux derives de ketolides
WO2004083185A3 (fr) Composes imidazole
WO2003053945A3 (fr) Nouveaux composes
SE0300908D0 (sv) Azaindole derivatives, preparations thereof, uses thereof and compositions containing them
WO2006092599A3 (fr) Composes chimiques
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MXPA05013050A (es) Derivados de bencimidazol, composiciones que los contienen preparacion de los mismos y usos de los mismos.
AU2003273473A1 (en) Novel substituted pyrazolo(1,5 less thanigreater thanaless than/igreater than)-1,3,5-triazine derivatives and their analogues, pharmaceutical compositions containing same, use thereof as medicine and methods for preparing same
WO2005118579A3 (fr) Composes chimiques
WO2003054001A3 (fr) Procede de preparation de derives d'echinocandines et leurs compositions

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase